The Living SpiritWhat is My Relationship With Myself?The Rudi-Grant Connection is derived from the Service in Army Medical Corps.
The Cap Badges and the Insignia of the British Royal Medical Corps and the Indian Army Medical Corps reveal the Rudi-Grant Connection. The Indian Army Medical Corps was created from the British Royal Army Medical Corps.
The Rudi-Grant Connection investigates my relationship with myself. Who am I?
In 1965, while I was a student of Human Anatomy at Kurnool Medical College, I had the opportunity to know about Dr. J. C. B. Grant (1886-1973), the author of Grant’s Atlas of Anatomy. The 5th Edition of his Atlas was published in 1962 and was available in India in our Medical College Library.
Born in Loanhead (south of Edinburgh) in 1886, Grant studied medicine at the University of Edinburgh Medical School and graduated with an M.B., Ch.B. degree in 1908. While at Edinburgh, he worked under the renowned anatomist Daniel John Cunningham. Grant became a decorated serviceman of the Royal Army Medical Corps during the First World War before moving to Canada. He established himself as an ‘anatomist extraordinary’ at the University of Toronto, publishing three textbooks that form the basis of Grant’s Anatomy. The textbooks are still used in anatomy classes today, and made unforgettable memories for those who found themselves in his classes nearly a century ago. One of Grant’s many accomplishments was establishing a division of histology within the department.
The Rudi-Grant Connection investigates my relationship with myself. Who am I?
As a medical student, I used Grant’s Atlas of Anatomy, the seminal work of Scottish-born Dr. John Charles Boileau Grant, who would become the chair of Anatomy at the University of Toronto in 1930 and retired in 1965.
Students continue to use Grant’s textbooks today, and for the more artistic anatomist there’s even a Grant’s Anatomy Coloring Book, published in 2018.
The Rudi-Grant Connection investigates my relationship with myself. Who am I?
At the University of Toronto, Dr.McMurrich, Chair of Anatomy was succeeded as chairman in 1930 by Dr. John Charles Boileau Grant. Dr. Grant wrote three text books, of which “An Atlas of Anatomy” (published in 1943) rapidly gained international prominence and is still, one of the most widely used anatomical atlases in the world. It is now known as “Grant’s Atlas of Anatomy” and is in its tenth edition. The atlas was based on a series of elegant dissections done either by Grant or by others under his supervision. Many of these dissections are currently housed in Grant’s Museum at the University of Toronto.
The Rudi-Grant Connection is about knowing the man, the building blocks and the structural units and organization of the human body. To defend the human existence, the Rudi-Grant Connection lays the emphasis on knowing the person who is at risk apart from knowing the agent posing the risk.
THE IDENTITY OF MULTICELLULAR HUMAN ORGANISM:
The Rudi-Grant Connection investigates my relationship with myself. Who am I?Dr John Daniel Cunningham (b. April 15, 1850, d. July 23, 1909), Scottish physician and professor of Anatomy. Cunningham’s Manual of Practical Anatomy has provided me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems.
Daniel John Cunningham was born on 15 April 1850 in Scotland. After his initial schooling at his home town, Crieff, he took up the study of medicine at the University of Edinburgh and passed with honours. He is best known for the excellent series of dissection manuals, namely Cunningham’s Dissection Manuals. Cunningham’s Manual of Practical Anatomy has provided me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems.
The Rudi-Grant Connection investigates my relationship with myself. Who am I?Dr John Daniel Cunningham (b. April 15, 1850, d. July 23, 1909), Scottish physician and professor of Anatomy. Cunningham’s Manual of Practical Anatomy has provided me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems.The Rudi-Grant Connection investigates my relationship with myself. Who am I?Dr John Daniel Cunningham (b. April 15, 1850, d. July 23, 1909), Scottish physician and professor of Anatomy. Cunningham’s Manual of Practical Anatomy has provided me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems.The Rudi-Grant Connection investigates my relationship with myself. Who am I?Dr John Daniel Cunningham (b. April 15, 1850, d. July 23, 1909), Scottish physician and professor of Anatomy. Cunningham’s Manual of Practical Anatomy has provided me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems.
I learned about the human body while dissecting the body in a systematic manner. The Manual of Practical Anatomy which guides us through this entire process was published in England. The author Dr. Daniel John Cunningham prepared the Manual while dissecting cadavers of British or Irish citizens. He had never encountered cadavers of Indian citizens. At Kurnool Medical College, Kurnool, Andhra Pradesh, India, where I was a student, the Department of Anatomy obtains dead bodies from Government General Hospital Kurnool and most of the deceased are the poor, illiterate, and uneducated people of that region. None of the deceased had the chance to know this man called Cunningham and Cunningham had no knowledge about the existence of these people who arrive on our dissection tables. But, as the dissection of the human body proceeds, inch, by inch, we recognize the anatomical parts as described by Cunningham. The manual also lists some anatomical variations and we very often exchange information between various dissection tables and recognize the variations mentioned. The dissections also involve slicing the organs and studying them, both macroscopically, and microscopically. We did not miss any part of the human body. So what is the Identity of this Human person or Human subject? How does the living Human organism maintain its Identity and Individuality? Apart from the Cultural Traditions of India, several Schools of Religious Thought claim that the Human Individual and its Identity is represented by Human Soul. Where does this soul exist in the human body? What is the location if the soul is present in the living person? Does man have a soul?How does the human organism acquires Knowledge about its own structures and the functions they perform?
What is my relationship with myself?
The problem of human identity. What is my relationship with myself?
What is my relationship with myself ? I have forgotten all other relationships. How many mirrors that I have looked into, yet I have forgotten my face.
The above lines are an attempt by me to translate into English the ‘ghazal’ titled “MUJH SE MERA KYA RISHTA HAI” by Mumtaz Rashid. The ‘ghazal’ is included in the music audio cassette (11/98), “RUBAYEE“ (Volume 1). The singer is India’s famous ghazal singer PANKAJ UDHAS. The cassette was released by Music India, Polygram India Ltd. The cassette includes “Rubayees” of Hakim Omar Khayyam translated into Indian language Urdu by Janab Zameer Kazmi and Janab Irteza Nishat. I would particularly invite all Farsi speakers to listen to these songs and appreciate the connection between Persian language and Urdu. This melodious Indian language Urdu represents a bridge that connects the people of IRAN with the people of INDIA.
Mujh Se Mera Kya Rishta Hai Lyric
Imaan ko bekaar na kar du ya rab Is jeene ko dushwar na kar du ya rab Is khauf se har shaam ko pee leta hu Main khud se bhi inkaar na kar du ya rab
Peene de mujhe bhar de mera paimana Duniya to hain ek uljha hua afsaana Jab tak mujhe maalum na ye ho jaaye Main aaya kahan se hu Kahan hain jaana
Mujh se mera kya rishta hai Mujh se mera kya rishta hai Har ek rishta bhul gaya Itne aaine dekhe hain Apna chehra bhul gaya Mujh se mera kya rishta hai
Ab to ye bhi yaad nahi hai Farq tha kitna dono me Ab to ye bhi yaad nahi hai Farq tha kitna dono me Us ki baatein yaad rahi Us ki baatein yaad rahi Aur uska lehja bhul gaya Itne aaine dekhe hain Apna chehra bhul gaya Mujh se mera kya rishta hai
Pyasi dharti ke hothon per Mera naam nahi to kya Pyasi dharti ke hothon per Mera naam nahi to kya Main wo baadal ka tukda hu Main wo baadal ka tukda hu Jis ko dariya bhul gaya Itne aaine dekhe hain Apna chehra bhul gaya Mujh se mera kya rishta hai
Duniya wale kuch bhi kahein Rashid apni majburi hain Duniya wale kuch bhi kahein Rashid apni majburi hain Uski gali jab yaad aayi hain Uski gali jab yaad aayi hain Ghar ka rasta bhul gaya Itne aaine dekhe hain Apna chehra bhul gaya Mujh se mera kya rishta hai Har ek rishta bhul gaya Mujh se mera kya rishta hai Har ek rishta bhul gaya Mujh se mera kya rishta hai
Who am I? From where I have arrived? Where am I going?
What is my relationship with myself? Rubaiyat of Persian poet Hakeem Omar Khayyam.
Human existence raises some fundamental questions about individual’s identity, the purpose in life and the nature of human relationships. I love Hakeem Omar Khayyam for he had asked himself these questions. Does the image I see in the mirror describe my true identity ? Unless I define my identity, how it would be possible to describe my relationship with others. If I do not know as to who I am, why should I contemplate on issues such as my purpose in life and my destination? Self-Knowledge is the key to answer questions about existence.
Sir, Who are you?
Guru Adi Shankaracharya has described his own identity.”Mano budhyaHankara, Chittani naaHam; Na karnam, na jihvaa, na cha gharana neytrey; Na cha vyoma bhumeerna tejo, na vaayuH; Chidananda roopaH, Shivo aHam, Shivo aHam.” His identity does not pertain to the four functions of the brain, the five organs of special sense, and also the Five Elements of Mother Nature. Sir, who are you? I am Shiva and Shiva alone whose identity is described as Sat+Chit+Ananda.
JAGADGURU’ Sri Adi Shankaracharya answers the above question. In six verses described as ” NIRVANA SHATKAM “, he states what he is not and as to what he could be.
I have no death, I have no fear; I do not belong to a category, the differences that we accrue as a result of caste, creed or occupation do not belong to me; I have no father, I have no mother and in fact, I am not born (it implies that I am an eternal entity), I have no relatives, I have no friends, I have no ‘GURU’, and I am not a disciple of anyone. But, I am the reflection of the image of ‘SAT+CHIT+ANANDA, I am that SHIVA and I am SHIVA.
I read that response from SHANKARA to acquire a sense of direction in my search for my identity. If I know, who I am, I could live in a relationship with myself. First of all, I need to forget that image, that reflection that I may have seen in the mirror.
The problem of human identity. What is my relationship with myself?
The Living SpiritThe Rudi-Grant Connection is derived from the Service in Army Medical Corps.The Cap Badges and the Insignia of the British Royal Medical Corps and the Indian Army Medical Corps reveal the Rudi-Grant Connection. The Indian Army Medical Corps was created from the British Royal Army Medical Corps.
The Cap Badges and the Insignia of the British Royal Medical Corps and the Indian Army Medical Corps reveal the Rudi-Grant Connection. The Indian Army Medical Corps was created from the British Royal Army Medical Corps.
The Rudi-Grant Connection reviews the Book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS
In 1965, while I was a student of Human Anatomy at Kurnool Medical College, I had the opportunity to know about Dr. J. C. B. Grant (1886-1973), the author of Grant’s Atlas of Anatomy. The 5th Edition of his Atlas was published in 1962 and was available in India in our Medical College Library.
Born in Loanhead (south of Edinburgh) in 1886, Grant studied medicine at the University of Edinburgh Medical School and graduated with an M.B., Ch.B. degree in 1908. While at Edinburgh, he worked under the renowned anatomist Daniel John Cunningham. Grant became a decorated serviceman of the Royal Army Medical Corps during the First World War before moving to Canada. He established himself as an ‘anatomist extraordinary’ at the University of Toronto, publishing three textbooks that form the basis of Grant’s Anatomy. The textbooks are still used in anatomy classes today, and made unforgettable memories for those who found themselves in his classes nearly a century ago. One of Grant’s many accomplishments was establishing a division of histology within the department.
The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS
As a medical student, I used Grant’s Atlas of Anatomy, the seminal work of Scottish-born Dr. John Charles Boileau Grant, who would become the chair of Anatomy at the University of Toronto in 1930 and retired in 1965.
Students continue to use Grant’s textbooks today, and for the more artistic anatomist there’s even a Grant’s Anatomy Coloring Book, published in 2018.
The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS
At the University of Toronto, Dr.McMurrich, Chair of Anatomy was succeeded as chairman in 1930 by Dr. John Charles Boileau Grant. Dr. Grant wrote three text books, of which “An Atlas of Anatomy” (published in 1943) rapidly gained international prominence and is still, one of the most widely used anatomical atlases in the world. It is now known as “Grant’s Atlas of Anatomy” and is in its tenth edition. The atlas was based on a series of elegant dissections done either by Grant or by others under his supervision. Many of these dissections are currently housed in Grant’s Museum at the University of Toronto.
The Rudi-Grant Connection is about knowing the human person, male and female, the building blocks and the structural units and organization of the human body. To defend the human existence, the Rudi-Grant Connection lays the emphasis on knowing the person who is at risk apart from knowing the agent posing the risk.
THE IDENTITY OF MULTICELLULAR HUMAN ORGANISM:
The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS. Dr. Cunningham’s Manuals of Practical Anatomy provide the understanding of the multicellular human organism, both male and female.
Daniel John Cunningham was born on 15 April 1850 in Scotland. After his initial schooling at his home town, Crieff, he took up the study of medicine at the University of Edinburgh and passed with honours. He is best known for the excellent series of dissection manuals, namely Cunningham’s Dissection Manuals. Cunningham’s Manual of Practical Anatomy has provided me the learning tools to know and understand the human body’s external and internal reality and its identity as described by Cells, Tissues, Organs,and Organ Systems that constitute the multicellular human organism.
The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS. Cunningham’s Manual of Practical Anatomy describes the structural organization of human male and female.The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS. Cunningham’s Manual of Practical Anatomy guides me in the investigation of man and woman.The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS. What is man? What is woman? Practical Anatomy provides accurate information about the reality of the multicellular human organism.The Law of Biogenesis states that organisms arise only by the reproduction of other organisms. This cell known as Oocyte develops into Human Ovum or Egg Cell which begins the life of a new human organism after an event called Fertilization. The Rudi-Grant Connection reviews the Book Matrudevobhava. This cell is generated using a creative process called Meiosis.The Human Egg Cell is conscious of its state of existence. It is goal-oriented and it serves the purpose of the Whole Organism (Mother) and displays functional subordination. If the Egg Cell is not fertilized, it has no further purpose, and it gets expelled from the body. It displays no tendency towards implantation or getting embedded into the maternal tissue to continue its existence. The Rudi-Grant Connection reviews the Book Matrudevobhava.Human life begins at conception. Father is the Originating Principle and Mother, the source of life, energy, and knowledge is the Providing Principle.When Knowledge is implanted in this Egg Cell, it becomes Conscious and aware of its own Existence and begins to grow and develop performing a variety of living functions. Hence, Life could be defined as “Knowledge in Action.” The Rudi-Grant Connection reviews the Book Matrudevobhava.SPIRITUALITY SCIENCE – CELLULAR BASIS OF SPIRITUAL FUNCTIONS – HUMAN OVUM, STRUCTURE AND FUNCTIONS. The Rudi-Grant Connection reviews the book Matrudevobhava.Fertilization of an egg by a sperm, conception occurs in the oviduct. Cleavage (cell division) begins in the oviduct. as the embryo is moved. toward the uterus. by peristalsis and the. movements of cilia. 3. Cleavage continues. By the time the embryo. reaches the uterus, it is a ball of cells. It floats in the uterus for. several days, nourished by. endometrial secretions. It. becomes a blastocyst. 4. Ovary. Uterus. Endometrium. From ovulation to implantation. Inner cell mass. Cavity. Blastocyst. Trophoblast. (a) Implantation of blastocyst. (b) Fertilization occurs. A sperm. enters the oocyte; meiosis of. the oocyte finishes; and the. nuclei of the ovum and sperm. fuse, producing a zygote. 2. Ovulation releases a. secondary oocyte, which. enters the oviduct. 1. The blastocyst implants. in the endometrium. about 7 days after conception. 5.The developmental stages of ovulated egg after fertilization. 2 cells, 4 cells, Morula, and Blastocyst. Fertilization occurs within the uterine tube. Sperm and Egg on Day 0. The blastocyst implants in the uterus Day 7. Ovary. Ovulated Egg. Muscle layer of Uterine wall and its inner lining Endometrium. (a) The first week of development.SPIRITUALITY SCIENCE – ESSENCE – IDENTITY – UNITY – EXISTENCE: THIS FERTILIZED HUMAN OVUM OR EGG CELL BEGINS THE LIFE JOURNEY OF MAN. FROM THE BEGINNING, THERE IS UNITY BETWEEN, BODY, MIND, SOUL, AND GOD. The Rudi-Grant Connection reviews the Book Matrudevobhava.Man’s life journey begins as an Embryo which gets implanted into the maternal tissues by about 6 days after its conception. Thus, mother is the source of Food and Energy to establish human life. Man has no existence in the absence of this positive Intraspecific Interaction between Embryo and Mother. The Rudi-Grant Connection reviews the Book Matrudevobhava.The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS. What is creation? What is creative potency? God and Mother Nature are not the same. God and the human Mother are not the same. Lord Krishna provides the clarification.The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS. The man is created with the Superior Energy of the LORD who provides the capacity to exploit matter and energy provided by Mother Nature. And yet, man and God are always separate while they are united for the purpose of mortal existence.Animate vs Inanimate Dualism. Man, Body, and Soul are united by LORD God or ‘PRABHU’ who still remains aloof, disinterested, or separate from both Animate and Inanimate Matter. GOD is a separate order distinct from Animate and Inanimate Matter. Fundamental Dualism is the reality of Creation. The Rudi-Grant Connection reviews the book Matrudevobhava.Spiritualism: The Rebbapragadas Family Photo. Dr. R. Anjaneyulu, M.D. former Professor of Gynaecology & Obstetrics, B.J. Medical College and Sassoon General Hospitals, Dean Faculty of Medicine, Pune University (Seated far Right) with his brothers and sister. The Rudi-Grant Connection reviews the Book Matrudevobhava.
M A T R U D E V O B H A V A
Ethical, Moral and Philosophical Aspects of
OBSTETRICS & GYNAECOLOGY
An Indian Perspective
By
DR R. ANJANEYULU, MD, DGO, FCPS
Emeritus Professor of Obstetrics and Gynaecology
B.J. Medical College and Sassoon Hospitals, Pune
Maharashtra State, India
Foreword by
Dr. K. Bhasker Rao, M.D., F.R.C.O.G., F.M.S.
Emeritus Professor of Obstetrics and Gynaecology
Madras Medical College
(Formerly Director, Institute of Obstetrics and Gynaecology,
Govt. Hospital for Women and Children, Egmore, Madras)
In my analysis, the book Matrudevobhava has failed to understand the concept called Parthenogenesis described in Reproductive Biology. It will be factually wrong to suggest that Parthenogenesis could account for the generation of human males such as Jesus, and the Pandava princes known as Karna, Dharmaraja, Bhima, Arjuna, Nakula, and Sahadeva. The book also fails to recognize the generation of the human form using a very creative reproductive process called Meiosis and the generation of variation in the inherited traits as explained by the Mendel’s Laws of Inheritance. The book does not address the issue of Fundamental Dualism, the distinction between God and Man or Woman. While celebrating the divinity of Motherhood, the book fails to acknowledge the Superior Energy mentioned by Lord Krishna that formulates all existence.The book fails to acknowledge the spiritual nature of intraspecific biotic interactions while describing the role of Immunological Tolerance and Immunological Enhancement that serve the purpose of the developing human embryo.
Byramjee Jeejeebhoy Medical College Pune. Dr. R. Anjaneyulu, M.D., D.G.O., FCPS. The Dean Faculty of Medicine, Pune University, the Emeritus Professor of Obstetrics & Gynaecology, B. J. Medical College and Sassoon Hospitals Pune. The Rudi-Grant Connection reviews the Book Matrudevobhava.The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS. Sassoon General Hospital, Pune, India.
R. Anjaneyulu; M.D., D.G.O.; F.C.P.S.
M A T R U D E V O B H A V A
Mother
The Universal Mother is in the form of Bhoomata who bears all of us ! She is the Prakriti or Shakti or energy without whom the world cannot exist. She is the same Shakti in the form of Goddess of Learning; Saraswati who helpsLord Brahma to create this world; in the form of Goddess Lakshmi; Goddess of wealth who helps Bhagwan Vishnu to protect the world bestowing health, happiness, prosperity and well-being of the people; in Goddess Parvati; she gave Shakti or energy to Lord Shiva to destroy the world.
She is the same Mother to whom we also pray as Durga during Navaratri, to destroy the evil forces and cut the knot of ignorance in our heart and also the quality of Ahamkara in us and bestows upon us knowledge and wisdom!
`The Universal Mother has many other manifestations – in the form of Gayatri – she protects us; as Ganga Bhavani – she gives us water for survival; as Gomata (cow) – she gives us milk for health the nourishment and as Mother Geeta(Bhagavadgeeta)whose door is open to any one who knocks and seeks refuge in distress in her bosom. Stree or Ammai is the incarnation of Shakti Swaroopa. Mother gives herself to the development of the child and works hard and sacrifices for the safety and survival of her children. It is this spirit of Tyaga or sacrifice that makes the value of motherhood great! In this world, no other person deserves to be more respected than MOTHER.
It is to the feet of all mothers of the world and the Supreme Mother that offer my Pranam and salutations while attempting to write this book.
SARVAMANGALA MANGALYE, SHIVE SARVARTHA SADHIKE
SHARANYE TRIAMBAKE GAURI, NARAYANI NAMOSTUTE
Oh Mother Durga, wife of Lord Shiva looking after the welfare of everybody and fulfilling all the desires, cherished by one and all, I am under your shelter and offer my Namaskarams to you!
Sarvasya ca ham hrudi Samnivisto
(Geeta Chapter 15)
I am seated in the hearts of all.
“Call the Lord by any name, Allah, Jesus, Rama or Krishna – One is referring only to the Divinity. Even the meaning of the words points to the same divinity. The word Allah Al-Divinity, Lah – to become laya or merge in it; Similarly Jesus (Yesu) means Ye – One and Su – Divinity. Rama constitutes three components of sounds Ra Aa Ma. Ra signifies Twam i.e. Brahma or Divinity, Ma signifies Twam; i.e., Thou, the Jiva or the individual and Aa connotes the kinship of identity of the two i.e., the Jiva and Brahma. The Lord is also secular in that the responds to anyone meditating on his name with purity and devotion in any language or religion. Thus Divinity is only one and the paths to reach Him are different”.
I have quoted quite often from the Divine messages of Bhagvan Sri Satya Sai Baba in this book including the above paragraph. His teachings are so lucid and simple that even a lay man like myself can understand and comprehend the essence or core of what is written in Geeta, Upanishads or Vedas. “One sees in his preaching’s a combination of Hindu concept of Vedic cosmic awareness, the Islamic concept of Allah as universe, the one who sustains us all and the Buddhist and Christian compassion”. Truly a great teacher and in the real sense, Guru, (one who removes ignorance from everyone’s mind). President Shankar Dayal Sharma said that ‘Bhagwan’s mission is to bring change in Naitika, Dharmika and Adhyathmic thoughts so that all of us strive to realise our own true nature; i.e. That Thou Art.” I pray and seek Bhagwan’s Blessings in writing this book.
Late Shri SAL Narayana Row, erstwhile Chairman Board of Direct Taxes was always a friend philosopher and guide to me. My brother-in-law, Dr B Dayananda Rao, is not only an eminent neurosurgeon but an erudite scholar of English Literature. I have had the good fortune of his having gone through the entire manuscript of this book and the benefit of his advice.
Dr Banoo Coyaji has, since he time I came to Pune been a source of great inspiration. A true karmayogi, her pioneering work in all aspects of maternal health and Safe Motherhood have throughout been the cardinal example to follow.
I have gained immensely from the discussions I have had with Pandit KL Gautam, a renowned Sanskrit and Hindi scholar and Dr Padmakar Vartak, who has an indepth knowledge and understanding of our traditions, philosophy and medicine. Both of them gave me valuable advice and information which I have duly incorporated in the book.
I have also had fruitful discussions with Doctors Sudhikumar, Mrs Rajlaxmi, Mrs Asha Joshi and Mrs Rashmi Gapchup. Mrs Jyotsna Apte had very kindly undertaken to make the line drawings. Dr Nishikant Shrotri and Dr Mrs Aparna Shrotri have given me valuable help and advice in printing the book. My grateful thanks to all of them.
Immunological Tolerance
Trophoblast is of foetal origin and has antigens of paternal type. In the blood flowing through the chorio-decidual space there are both foetal cells from the trophoblast and the maternal cells. Yet the antigens on the trophoblast are either masked, shed, or modified at the cell surface and do not express their antigenicity. On the part of the mother (as described above) the maternal cells in decidua do not produce immune response in spite of the production of the specific antibodies (humoral or cellular).
In short, maternal cells and foetal cells develop tolerance to each other and this is classically known as Immunological Tolerance of Pregnancy. In this way no antigen antibody reaction occurs thereby preventing rejection of the graft foetus by the host mother, which in fact accepts the foetus.
Immunological Enhancement.
The other important phenomenon that occurs in normal pregnancy is that the humoral antibodies (LGG) unite with the helper T-cells and blocks and protects the placental antigens and renders them immune from the T-cells (killer cells) attack. These antibodies are known as blocking antibodies and the phenomenon as Immunological Enhancement. Such protection from blocking antibodies is not observed in abnormal reproductive states like abortion or toxaemias of pregnancy.
HETEROLOGOUS ARTIFICIAL INSEMINATION OR ‘AID’ – ADOPTION : ETHICAL CONSIDERATIONS
‘If in the course of investigations an irremediable barrier for fertilization is found in the husband, the gynaecologist should explain the hapless predicament to the barren couple and in a sympathetic way, guide the couple to adjust their married philosophy to that of a childless union. There are of course two alternatives – neither of which should be suggested by the gynaecologist. They may decide to adopt a child or have the wife to submit to heterologous artificial insemination (AID).’
WHAT DO OUR SHASTRAS SAY REGARDING HETEROLOGOUS ARTIFICIAL INSEMINATION OR ‘AID’?
It is interesting to know the view prevalent in our Puranas and scriptures. It was a regular accepted procedure to call some male to fertilize the woman in case the man was impotent and this is called Niyoga. This applied even to kings. In Mahabharata King Santanu’s wife Satyavati requested Vedavyasa to impregnate Amba, Ambika and Ambalika, when their husbands died without leaving any progeny. That was how Dhrutarashtra and Panduraja were born. Unfortunately Panduraja was cursed by a Rishi couple (when he mistakenly killed them) that he would die the moment he tries to enjoy with his wives Kunti and Madri. Pandu told Kunti to have children from whomsoever she desired. Kunti was given five boons (varas) by Rishi Durvasa Mahamuni when she served the Rishi before her marriage. In her ignorance Kunti wanted to test the boons or varas. She thought of Bhagwan Surya and when the Lord really came she was stunned. Karma was born then. It was written by Vedavyasa in Mahabharata that Karna was born not of consummation of marriage but by Parthenogenesis or self fertilization. It is the solar energy that was responsible. In the same way, after marriage, when Pandu told Kunti to have children from someone else, she refused. Keeping in mind the boons she prayed to Yama Dharma Raja; i.e. lord of Death. He typifies the energy which hold the universe and is protector of Dharma like Lord Brahma. That was how Dharmaraja was born. Kunti then prayed to Lord Vayu Deva the energy which is blowing and present everywhere just like electromagnetic waves and Bhima was born. Arjuna was born from the blessings of Lord Indra who represents the Atman. Lord said He is Indra among all devatas. Then Kunti requested Ashwini Devatas to bless Princess Madri. Ashwini Devatas are twins who represent energy one as a positive charge and other as a negative charge, without which current cannot pass through. By the blessings these Devatasi Madrigave birth to Nakula and Sahadeva. It must be emphasied again that Pandavs as well as Karna were Varaputras and also born by parthenogenesis. In his sankalpa to be born again and again whenever there is a deterioration of Dharma Lord Almighty takes birth on the earth, as He has promised’……Sambhavami Yuge Yuge.’ He had taken the birth of Lord Jesus again through Parthenogenesis. So Kunti, Madri and Virgin Mary are all incarnations of purity and virtue.
What is Parthenogenesis?
The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS. What is creation? Human reproduction involves the creative mechanism called Meiosis that leads to the creation of new human genomes all the time.The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS. What is creation? The creative process called Meiosis always ensures the generation of a new human genome that never existed before and will never exist again in the future.The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS. What is Parthenogenesis? Human male baby always needs both male and female parents.The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS. What is Parthenogenesis? Male baby always needs two parents.The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS. What is Parthenogenesis? Human male baby always needs both male and female parents.The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS. What is Parthenogenesis? The production of human male baby requires the Y chromosome apart from the X chromosome.The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS. What is creation? Mendel’s Laws account for the magic of creation. Every newborn arrives with a new, unique genome.The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPS. What is creation? Mendel’s Laws account for the magic of creation. Every newborn baby arrives as an original member of the human species.
The Laws of Creation: Bhagavad Gita: Chapter 7, Verse 5
BG 7.5: Such is My inferior energy. But beyond it, O mighty-armed Arjun, I have a superior energy. This is the jīva śhakti (the soul energy), which comprises the embodied souls who are the basis of life in this world.
Commentary
Shree Krishna explains that beyond the eight-fold prakṛiti, the material energy, which He says is inferior; there exists another that is far more superior. This energy is completely transcendental as compared to the lifeless matter. It is His spiritual energy, the jīva śhakti, which includes all the living souls of the world. Now, He has moved from explaining material science toward the spiritual realm.
Many great philosophers of India have given their perspectives and described the relationship between God and the jīva, the individual soul. For example, the non-dualists state: jīvo brahmaiva nāparaḥ “The soul itself is God.” But this concept gives rise to several questions, such as:
How can the soul itself be God? God is most powerful, and Maya is His subservient energy. The souls are always overpowered by; Maya. Then is Maya stronger than God?
The individual soul is always; gripped by ignorance and misery. It needs a continuous reminder from the saints and scriptures, even about its existence and purpose. How can God, who is all-knowing, be considered a soul which is subject to ignorance?
The Vedas repeatedly state that God is all-pervading in this world and beyond. Similarly, individual souls should also be able to exist anywhere at any given time. Then what about the question of going to heaven or hell after death?
There is only one God, but the souls are countless. If the soul itself is God, then there should be many Gods. Therefore, the claims by non-dualistic philosophers that the soul itself is God are inconclusive.
The dualist philosophers’ state that the souls and God are separate. Even though it may answer some of the above questions, yet it is still an incomplete philosophy in light of what Shree Krishna states in this verse. He says that the soul is a part of jīva śhakti God’s spiritual energy. And as explained earlier, Maya, the material energy, is also His subservient. Thus, God is supreme; He is the governor of both the lower material and the higher spiritual energies. Now let us see what the scriptures and various saints have said:
“Just as the sun resides in one place but its sunlight pervades; the entire solar system. Similarly, there is one God, who by His infinite powers pervades the three worlds.”
“The soul is the energy of God, while He is the Supreme Energetic.”
Once we understand and accept that the soul is a small part of God’s infinite energy, the concept of non-duality of the entire creation becomes clear. Energies can exist concurrently within the same energetic. For example, fire contains both heat and light, which are different entities and have different properties. But they are part of the same fire which emits them. Likewise, God as the Energetic and the souls His energy can be considered one. At the same time, due to their distinct properties, both entities are different from each other. Jagadguru Kripaluji Maharaj has encapsulated and perfectly expressed Shree Krishna’s statement in this and the previous verse:
jīvu’ ‘māyā’, dui śhakti haiñ, śhaktimān bhagavān śhaktihiñ bheda abheda bhī, śhaktimān te jān (Bhakti Śhatak verse 42)
“The soul and Maya are both energies of God. Hence, they are both one with God and also different from God.”
Considering the unison of both; the Energetic and His energies, it is stated that God and His creation are non-different. The entire world is a veritable form of God.
sarvaṁ khalvidaṁ brahma (Chhāndogya Upaniṣhad 3.14.1) “All is Brahman.”
īśhāvāsyam idam sarvaṁ (Īśhopaniṣhad 1) “Everything that exists in the world is God.”
puruṣha evedaṁ sarvaṁ (Śhwetāśhvatar Upaniṣhad 3.15) “The Supreme Divine Personality is everything that exists.”
According to these Vedic verses, there is only one God and nothing else. Yet, when we consider the Energetic and energy concept, there is diversity within this unity and an incredible variety. God, the souls, and matter, all three are different entities with different properties. God is Supremely sentient; He is the source of both the souls and the matter. Yet, souls are sentient, and the inanimate matter insentient.
The scriptures also state the existence of three entities in creation:
“There are three entities in existence: 1) Living Matter with Forms and the Forms are perishable. 2) Non Living Matter or Chemical Elements and the individual souls (Jeev Atman) who are imperishable. 3) God, who is the controller of both matter and the souls. By meditating upon God, uniting with Him, and becoming more like Him, the soul is free from the world’s illusion.”
The Vedas have expounded on both dualistic and non-dualistic concepts. Jagadguru Shree Kripaluji Maharaj has upheld the concepts of concurrent coherence, yet variance between the soul and God. This means God and the soul are one because of unity and not identity; yet, separate from each other as God, the Supreme Controller keeps Himself aloof, distant and even disinterested in His own Creative actions and activities.
The Rudi Connection at Whole Foods joins the Maha Navratri Celebration of the Divine Mother
The Rudi Connection at Whole Foods joins the Maha Navratri Celebration of the Divine MotherThe Rudi Connection at Whole Foods joins the Maha Navratri Celebration of the Divine Mother. Navratri Celebration From Monday, September 26 to Wednesday, October 05, 2022.The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. God both Male and Female.The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022 – NINE-NIGHT CELEBRATION OF DIVINE POWER, LOVE, MERCY, GRACE, AND COMPASSION TO SECURE HEALTH, WEALTH, WISDOM, AND PERFECT WELL-BEING OF MANKIND.
In Physics, Power/Energy/Force is not associated with gender. But, when living things exist as male and female, the description of Power/Energy/Force may have gender association. In the Indian tradition, ‘Deva’ means God and ‘Devi’ means Goddess. Devi in Indian tradition is the personification of God’s Supreme Power/Force/ Energy or ‘Shakti’. To fully account for the human existence, the man needs two distinct or separate Principles that come together to produce the harmonious singular identity of the man. The issue is not about God’s gender. Father Principle is called the Originating Principle. Mother Principle is called the Source Principle, for Mother is the Source of Matter, Energy, and Knowledge to establish Life of a Living Thing. Father provides Identity to the human form, Mother provides Substance, the structural and functional basis of the human form.
The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. GOD AS MALE AND FEMALE. GOD IS THE SUPREME BEING AND DESCRIBED AS OMNIPOTENT. THIS POTENCY OR POWER IS CALLED ‘SHAKTI’ IN THE SANSKRIT LANGUAGE. DEVI IS THE PERSONIFICATION OF ‘SHAKTI’. SHE DISPLAYED THIS GREAT POWER IN SLAYING OF A DEMON KING CALLED “MAHISHASURA.”The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. Shardiya Navratri refers to the Navratri Celebration during the Sharad Ritu or Autumn Season.
During 2022, Indians celebrate ‘DEVI NAVRATRI’ or ‘SHARAD NAVRATRI’ from Monday, September 26, to Wednesday, October 05. The term ‘Nav’ or ‘Nava’ means Nine. ‘Ratri’ means Night. This celebration happens in the lunar month called ‘ASVAYUJA’ (or ASHWAYUJA – September – October), the month in which Full Moon Day is associated with the first star (Tithi) called ‘ASVINI’ in Indian Astrology. Sharad Navratri commences on the first and ends on the tenth day of the bright half of the 7th Lunar month, Ashwin. The name “SHARADIYA” refers to the name of the Season or “RITU” called Sharad Ritu or Autumn.
The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022 – GOD AS MALE AND FEMALE. DEVI OR SHAKTI IS OFTEN CALLED ‘DURGA’ FOR SHE IS EMBODIMENT OF GREAT STRENGTH. SHE IS ALSO CALLED BHADRAKALI, JAGADAMBA, ANNAPURNA, SARVA MANGALA, BHAIRAVI, CHANDIKA, LALITA, BHAVANI, AND MOOKAMBIKA.
Devi or Shakti is often called ‘DURGA’ for She is the embodiment of great strength. She is also called BHADRAKALI, JAGADAMBA, ANNAPURNA, SARVA MANGALA, BHAIRAVI, CHANDIKA, LALITA, BHAVANI, AND MOOKAMBIKA. During the 9-Night or Navratri festival, Indians worship nine different forms of Goddess Durga with 1,000 names. She is simply adored as Divine Mother and often addressed as ‘MOTHER’ (“MATA” or “MAA”) whatever may be the name or form She assumed on different occasions.
The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. DEVI NAVRATRI – SHARAD NAVRATRI – GOD AS MALE AND FEMALE. NINE DIFFERENT FORMS OF MOTHER DURGA OR SHAKTI ARE REMEMBERED WITH DEVOTION AND ADORATION.
Goddess Shakti has three Supreme Forms called DURGA, SARASVATI, and LAKSHMI. In India, the traditions vary from region to region. First 3 – days of Navratri are dedicated to Goddess Durga, following 3-days are dedicated to Goddess Lakshmi and concluding 3-days are dedicated to Goddess Sarasvati or Goddess of Knowledge, Wisdom, and Speech. Saturday, October 01, 2022, the Sixth Day or Shashti is dedicated to Goddess called ‘KATYANI’ (legendary daughter of a devotee by name ‘KATA’). On this day, Goddess Sarasvati is also worshiped for this day is associated with a Nakshatra (Star) called ‘MOOLA’.
DEVI NAVRATRI CELEBRATION-SEPTEMBER 26 TO OCTOBER 04, 2022 CALENDAR:
The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration From October 07 TO 15, 2021
Monday, September 26, Day 1 – Pratipada, Ghatasthapana, Shailputri Puja
Tuesday, September 27, Day 2 – Dvitiya, Chandra Darshana, Brahmacharini Puja
Wednesday, September 28, Day 3 – Tritiya, Sindoor Tritiya, Chandraghanta Puja
Thursday, September 29, Day 4 – Chaturthi, Kushmanda Puja, Vinayaka Chaturthi, Upang Lalita Vrat
Friday, September 30, Day 5 – Panchami, Skandamata Puja, Sarasvati Avahan
Saturday, October 01, Day 6 – Shashthi, Katyayani Puja.
Sunday, October 02, Day 7 – Saptami, Kalaratri Puja
Monday, October 03, Day 8 – Ashtami, Durga Ashtami, Sarasvati Puja, Mahagauri Puja.
Tuesday, October 04, Day 9 – Navami, Ayudha Puja, Navami Homa, Navratri Parana.
Wednesday, October 05, Day 10 – Dashami, Durga Visarjan, Vijaya Dashami.
The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. GOD AS MALE AND FEMALE – FIRST NIGHT OF NAVRATRI IS CALLED PRATIPADA. DEDICATED TO GODDESS SHAILAPUTRI, DAUGHTER OF RULER OF MOUNTAINS. SHE IS ALSO KNOWN AS PARVATI, HEMAVATI, SATI BHAVANI AND OTHERS.The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. GOD AS MALE AND FEMALE. FIRST NIGHT OF NINE-NIGHT CELEBRATION.The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. CELEBRATION OF DIVINE POWER. NAVRATRI, Second Night, OR DVITIYA, DEDICATED TO GODDESS BRAHMACHARINI.The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. Third Night, Tritiya, DEDICATED TO GODDESS CHANDRAGHANTA. The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. GOD AS MALE AND FEMALE. THE FOURTH NIGHT IS CALLED CHATURTHI. GODDESS KUSHMANDA REPRESENTS CREATIVE POWER, AND SHE EXPRESSES A SENSE OF JOY FOR HER OWN CREATION. The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. GOD AS MALE AND FEMALE. GODDESS OF FOURTH NIGHT OR CHATURTHI IS KNOWN AS KUSHMANDA.The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. GOD AS MALE AND FEMALE. GODDESS OF FIFTH NIGHT OR PANCHAMI IS KNOWN AS SKANDAMATA, MOTHER OF SKANDA OR KARTIKEYA. The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. GOD AS MALE AND FEMALE. GODDESS OF SIXTH NIGHT IS KNOWN AS KATYAYANI.The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. GODDESS SARASVATI PUJA OR WORSHIP ON THE EIGHTH NIGHT, ASHTAMI, MONDAY, OCTOBER 03, 2022. The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. GOD AS MALE AND FEMALE. GODDESS OF SEVENTH-NIGHT OR SAPTAMI IS KNOWN AS KALRATRI (BLACK OR DARK NIGHT), AND SUBHANKARI FOR SHE GIVES PROTECTION FROM TROUBLE.The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. GOD AS MALE AND FEMALE. GODDESS OF EIGHTH NIGHT OR ASHTAMI IS KNOWN AS MAHA GAURI. The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. GOD AS MALE AND FEMALE. GODDESS OF NINTH NIGHT OR MAHARNAVAMI IS KNOWN AS SIDDHIDATRI FOR SHE BESTOWS ASHTA SIDDHIS.The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. The Ninth Night is dedicated to Goddess Siddhidatri.The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. GOD BOTH MALE AND FEMALE. DEVI OR GODDESS HAS THREE SUPREME FORMS CALLED SARASVATI, LAKSHMI, AND PARVATI. THESE NAMES DESCRIBE DIFFERENT ATTRIBUTES OF GOD’S OMNIPOTENCE.The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from September 26 to October 05, 2022. GOD BOTH MALE AND FEMALE. GODDESS DURGA IS PERSONIFICATION OF GOD’S OMNIPOTENCE.The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from Monday, September 26, following the New Moon Day on Sunday, September 25. and concludes on Wednesday, October 05, 2022.The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from Monday, September 26 to Wednesday, October 05, 2022. HINDU CALENDAR OR PANCHANGA.The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from Monday, September 26 to Wednesday, October 05, 2022. DEVI NAVRATRI – PHASES OF MOON ASSOCIATED WITH FORMS OF GODDESS SHAKTI.The Material Basis of Spirituality Science. Spiritual Optics. 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A HYMN IN PRAISE AND WORSHIP OF GODDESS DURGA DEVI.The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from Monday, September 26 to Wednesday, October 05, 2022. NINE-NIGHT CELEBRATION, DAY – 9, MAHA NAVAMI, AYUDHA PUJA, WORSHIP OF ALL WEAPONS, TOOLS, EQUIPMENT USED BY MAN TO ACCOMPLISH ACTION.The Material Basis of Spirituality Science. Spiritual Optics. The earthly manifestation of the Divine Mother. Navratri Celebration from Monday, September 26 to Wednesday, October 05, 2022. NINE-NIGHT WORSHIP OF DIVINE POWER, LOVE, GRACE, AND COMPASSION TO ACCOMPLISH VICTORY OF GOOD OVER EVIL FORCES. 10th DAY, DASAMI IS KNOWN AS VIJAYA DASAMI OR DUSSEHRA.The Rudi Connection at Whole Foods joins the Maha Navratri Celebration of the Divine Mother.
The Rudolf-Rudi Connection at Whole Foods. The concept of Whole Inheritance
The Rudi-Grant Connection reviews the book Matrudevobhava by Dr. R. Anjaneyulu, M.D., D.G.O., FCPSSPIRITUALITY SCIENCE – THE KNOWER – THE KNOWING-SELF: MALE OR FEMALE, THE ENTIRE HUMAN ORGANISM IS DERIVED FROM A SINGLE FERTILIZED EGG CELL . HOW IS THE IDENTITY AND INDIVIDUALITY IS ESTABLISHED AND IS KNOWN IN THIS COMPLEX MULTICELLULAR ORGANISM?
What is inheritance?
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance goes beyond the Mendel’s Laws of Inheritance.
Inheritance is the process by which genetic information is passed on from parent to child. This is why members of the same family tend to have similar characteristics.
We actually have two genomes each
We get one copy of our genome from each of our parents
Inheritance describes how genetic material is passed on from parent to child.
How is genetic material inherited?
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance.
Most of our cells contain two sets of 23 chromosomes (they are diploid).
An exception to this rule are the sex cells (egg and sperm), also known as gametes, which only have one set of chromosomes each (they are haploid).
However, in sexual reproduction the sperm cell combines with the egg cell to form the first cell of the new organism in a process called fertilization.
This cell (the fertilized egg) has two sets of 23 chromosomes (diploid) and the complete set of instructions needed to make more cells, and eventually a whole person.
Each of the cells in the new person contains genetic material from the two parents.
This passing down of genetic material is evident if you examine the characteristics of members of the same family, from average height to hair and eye colour to nose and ear shape, as they are usually similar.
What is Cytoplasmic Inheritance?
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance.
Cytoplasmic inheritance is a type of inheritance which involves DNA of cytoplasmic organelles. In this inheritance, the offspring receives genes from the cytoplasmic organelles (plasma genes or extranuclear genes). Mitochondria and chloroplasts contain genomes composed of DNA. This organelle DNA travels from the mother egg cell to zygote. However, compared to nuclear inheritance, a small number of genes are inherited by the cytoplasmic inheritance. Moreover, it does not follow the Mendelian inheritance pattern, unlike nuclear inheritance.
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance.
What is Nuclear Inheritance?
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The term Nuclear Inheritance refers to the inheritance of genetic traits such as Blood Type A, B, and O
Nuclear inheritance occurs due to the genes present on the chromosomes. Therefore, the mother nucleus and father nucleus equally contribute to nuclear inheritance. Moreover, the offspring inherits millions of genes from parents via nuclear inheritance.
WHOLE MENDELISM-ORIGIN OF LIFE: Human interest in Coloration lead Gregor Mendel to conduct his famous studies that established the science called Genetics. He conducted experiments studying the white or pinkish flowers of Pea (Pisum sativum) plants.
I coined the phrase ‘Whole Mendelism’ to interpret the information about Biogeneration and Propagation using the mechanism of reproduction. Mendel’s Laws of Inheritance describe the transmission of hereditary traits from parent species to offspring. However, the story of Inheritance as described in Biology is not ‘Whole’ or complete for it fails to include other important aspects of ‘Inheritance’.
Cells are the building blocks of life. Each living Cell has three basic components, 1. Nucleus or genetic material, 2. Corporeal substance, living matter called protoplasm, cytoplasm, or cytosol which has several kinds of intracellular organelles with membranes, and 3. Limiting Membrane called Cell Membrane, Plasma Membrane or Biological Membrane with which a living Cell separates itself from its surrounding environment including other living cells.
Modern Evolutionary Biologists interpret Theory of Evolution chiefly as that of transmission of genetic traits giving attention to genes and alterations of genetic information or mutation. They do not give attention to the Maternal Cytoplasmic Inheritance and Inheritance of Biological Membrane when a Mother Cell reproduces to develop Daughter Cells.
I account for my human existence coining the phrase Whole Inheritance which includes the contributions of the Divine Providence, the Father or Paternal Inheritance, and the Mother or Maternal Inheritance. The term inheritance must include the inheritance of Matter and Knowledge apart from the genes which are involved in the inheritance of genetic traits as the fact of existence needs the support from an external environment at any given time and place.
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance.
The Divine Providence ensures the creation of the newborn who arrives in a physical and social environment to exist as an Individual with Individuality, an original, one of its own kind of object even if the birth involves the use of reproductive technology such as the production of genetically identical clones.
The Concept of Whole Inheritance
The Rudolf-Rudi Connection at Whole Foods.. The Concept of Whole Inheritance. The Human Genome is just one dimension of the 3-dimensional inheritance.
The establishment of the human existence primarily involves three kinds of inheritance. 1. The Inheritance of the Human Genome, 2. The Cytoplasmic Inheritance which includes the inheritance of the Cell, Plasma, or Biological Membrane apart from cytoplasmic organelles containing DNA such as the mitochondria, and 3. The Inheritance of Physical and Social Environment that supports the existence
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance. The Rudi or Rudolf Connection at Whole Foods. The Concept of Whole Inheritance.
The Inheritance of Cell or Plasma Membrane:
Living cells have a corporeal substance called Protoplasm that has the ability of Spiritual Biotic Interactions. The Biological Membrane or Cell Membrane separates the cell from its environment and other living cells present in the environment. Cells use unique proteins, biological molecules and receptor sites to recognize the other living cells and use chemical signals to facilitate the interactions. Such interactions between living cells have the characteristics of consciousness or awareness.
The Functions of Cell Membrane or Biological Membrane:
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance.
1. Protection: It protects the cell from its surroundings or extracellular environment. Plant cell possess wall over the plasma membrane for extra protection and support.
2. Holding cell contents: Plasma membranes hold the semi fluid protoplasmic contents of the cell intact; thus keeping the individuality of the cell.
3. Selective Permeability: Cell membrane allows only selected or specific substances to enter into the cell and are impermeable to others.
Gases like O2 and CO2 can diffuse rapidly in solution through membranes.
Small compounds like H2O and methane can easily pass through where as sugars, amino acids and charged ions are transported with the help of transport proteins.
The size of the molecules which can pass through the plasma membrane is 1-15 A0. This property is responsible for keeping a cell ‘as a cell’, an individual unit.
4. Shape: It maintains form and shape of the cell. It serves as site of anchorage or attachment of the cytoskeleton; thus providing shape to the cell (especially in animal cells without cell wall).
5. Organelles: Cell membrane delimits or covers all sub-cellular structures or organelles like nucleus, mitochondria, plastids, Golgi apparatus, endoplasmic reticulum, microbodies etc. thus protecting them form the surroundings and also helps in maintaining a constant internal environment.
6. Compartmentalization: Cell membrane separate the cells from their external environment and cell organelle from cytosol. It help the cells and their organelles to have their own microenvironments, structural and functional individuality.
7. Cell Recognition: With the help of glycolipids and glycoproteins on its surface, cell membranes are able to differentiate similar cells from dissimilar ones, foreign substances and cells own materials. Cell recognition is useful for tissue formation and defence against microbes.
8. Antigens: Cell membranes possess antigens which determine blood grouping, immune response, acceptance or rejection of a transplant (graft rejection by MHC’s on plasma membrane).
9. Microvilli: They are microscopic finger like projections of plasma membrane present on some cells like intestinal epithelial cells, which are involved in a wide variety of functions, including increasing surface area for absorption, secretion, cellular adhesion etc.
10. Sheaths of cilia and flagella: Cilia and flagella are projections from the cell; made up of microtubules which are covered by an extension of the plasma membrane.
11. Cytoplasmic bridges in plasmodesmata and gap junctions: Plasmodesmata in plant cells and gap junctions in animal cells; meant for intercellular transport and communication, form cytoplasmic bridges between adjacent cells through plasma membrane.
12. Endocytosis and Exocytosis: Bulk intake of materials or endocytosis occurs through development of membrane vesicles or invagination and engulfing by plasma membrane.
Exocytosis: It is reverse of endocytosis that provides for releasing waste products and secretory materials ot of the cells with the help of plasma membrane.
13. Impulse transmission in neurons: The transmission of a nerve impulse along a neuron from one end to the other occurs as a result of electrical changes across the plasma membrane of the neuron
14. Cell metabolism: Cell membranes control cell metabolism through selective permeability and retentivity of substances in a cell.
15. Electron transport chain in bacteria: In bacteria; Electron transport chain is located in cell membrane.
16. Osmosis through cell membrane: It is movement of solvent molecules (generally water) from the region of less concentrated solution to the region of high concentrated solution through a semi permeable membrane. Here the semi permeable membrane that helps in osmosis is the cell membrane. Eg: Root cells take up water from the soil by osmosis
17. Carrier proteins for active transport: They occur in the cell membranes and control active transport of substances. Example, GLUT1 is a named carrier protein found in almost all animal cell membranes that transports glucose across the bilayer or plasma membrane.
18. Plasma Membrane enzymes: Many enzymes are present on the plasma membrane with wide variety of catalytic activity. Example: Red blood cell plasma membranes contain a number of enzymes such as ATPases, anion transport protein, glyceraldehyde 3-phosphate dehydrogenase, protein kinases, adenylate cyclase, acetylcholinesterase.
19. Cell Membrane Receptors: Receptor on the plasma membrane performs signal transduction, converting an extracellular signal into an intra-cellular signal. Membrane possess receptors for hormones, neurotransmitters, antibodies and several other biochemicals.
20. Plasma membrane assisted Cell movements: Undulation and pseudopodia are cell membrane phenomenon involved in cell movement. Amoeba, macrophages and WBCs move with the helps of temporary organelles like pseudopodia. Pseudopods are temporary cytoplasmic projections of the cell membrane in certain unicellular protists such as Amoeba. Some mammalian cells such as fibroblasts can move over a solid surface by wave like undulations of the plasma membrane.
The Divine Principle has to be both male and female and in this article, I present the feminine aspect of Divine Principle as “Whole Angel”, the harmonious blending or coming together of Angel of Beauty, Angel of Mercy, and Angel of Knowledge. My understanding of Mother and Motherhood comes from the study of the building blocks of Life. The most important building block of human life is the fertilized Egg Cell.
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The newborn baby upon separation from its mother begins life as an independent living entity by initiation of its vital, living functions such as Respiration and Circulation. To survive in physical world, the baby needs the ability to breathe on its own and circulate the vital supply of Oxygen to all tissues and organs of the entire body.
The Father and the Mother – The Principles governing Life:
Lord Shiva and Goddess Parvati – The Indian Tradition describes them as the First Couple or ‘Adi Dampatulu’ or the Original Father and Mother of humans. The Tradition recognizes the existence of a Father and a Mother Principle.
Father is described as the male parent, an ancestor, an originator, and as a Controller. Very often, God is considered as both the Father and the Mother of all life forms. Mother is described as the female parent and something that is regarded as a ‘Source’. Father may be viewed as the ‘Prime Cause’ and Mother is the Source of ‘Prime Energy’. Mother is the source of energy in performance of all kinds of actions and in accomplishment of all kinds of work. The Mother Principle represents the Endeavor/Work/Effort that makes action possible. If Life is defined as function at the level of biological molecules, Mother represents the Source or the Origin of these organic molecules; Mother is the Source of Energy for the synthesis of these organic molecules; and Mother is the Source of Knowledge that provides the ability of recognition and the ability to use the molecules in a sequential manner to manage the biochemical reactions of these organic molecules to function as Life.
MOTHER – SOURCE OF LIFE:
BHARAT DARSHAN – DEVI NAVRATRI – GOD BOTH MALE AND FEMALE. DEVI OR GODDESS HAS THREE SUPREME FORMS CALLED SARASVATI, LAKSHMI, AND PARVATI. THESE NAMES DESCRIBE DIFFERENT ATTRIBUTES OF GOD’S OMNIPOTENCE.
The complex, multicellular human organism begins as a single cell. That single cell is the source of life, energy, and knowledge.
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance. The Biological Dictum states “EX OVO OMNIA” – Everything comes from the Egg.The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance.The Biological Dictum – “OMNIS CELLULA E CELLULA” means all cells from cells.The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance of Life, Energy, and Knowledge.The Law of Biogenesis states that organisms arise only by the reproduction of other organisms. This cell known as Oocyte develops into Human Ovum or Egg Cell which begins the life of a new human organism after an event called Fertilization.
I, as a human organism exist in this world as I arrived from a previously existing ‘Mother Cell’. By repeated cell growth and cell division or replication known as ‘Mitosis’, the human organism grows and develops into a form containing thousands of billions of cells. This process of development is called ‘Morphogenesis’ which involves not only cell growth but differentiation into specialized types of cells. All the tissues and organs of which the human body is composed have originally developed from a microscopic cell known as ‘Ovum’ or the ‘Egg Cell’. This Ovum or Egg Cell may be regarded as a perfect cell and could be described as ‘Mother Cell’. All the solid tissues in the human body can be shown to consist largely of similar cells; it is true that they may differ, but they are essentially similar to an Ovum. The Ovum is a reproductive cell that is adapted to meet the nutritional requirements of the early developmental stages of the embryo. It is always a large cell because it contains sufficient cytoplasmic substance for the development of a self-sufficient embryo. Some of the substance which is packaged in yolk particles contains cell components; typically an Ovum contains sufficient quantities of components for many cells. Thus the Ovum need not grow as it divides; as the nuclei divide, the cytoplasm subdivides until the Ovum consists of a large number of normal-sized cells. By contrast, the male reproductive cells known as ‘Spermatozoa’ contain very little cytoplasm and they cannot further divide into new cells.
THE SOURCE OF LIFE – PROTOPLASM:
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance of Life, Energy, and Knowledge.There is similarity between the cells of a man and that of his Mother Cell or Egg Cell called Ovum.The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance.The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance.The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance.
The most significant feature of the similarity between the cells of a man and that of the ‘Mother Cell’ from which he had arrived is presence of a soft gelatinous, semi-fluid, granular material inside the cell. This substance known as ‘Protoplasm’ is similar to that found in the Ovum. The Ovum consists of this viscous, translucent, colloidal substance enclosed in a membrane called Plasma Membrane. A small spherical body called nucleus is embedded in the protoplasm. The protoplasm could also be differentiated into cytoplasm and nucleoplasm based upon its location. Cytoplasm refers to protoplasm located outside the nucleus. Nucleoplasm refers to protoplasm located inside the nucleus. The two essential features of any living cell in the human body are that of presence of protoplasm and the nucleus.
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. SPIRITUALISM AND CONSCIOUSNESS: Amoeba proteus is a conscious, living organism as it has the ability to perform vital, living functions.
The most striking characteristics of protoplasm are its vital properties of “Motion” and “Nutrition”. Protoplasm has the intrinsic power to change its shape and position. Motion of protoplasm is called ‘amoeboid movement’ as it resembles the movements observed in the Amoeba proteus animalcule. Nutrition is the power which protoplasm has of attracting itself the materials necessary for its growth and maintenance from surrounding matter and environment. The Egg Cell or the Ovum is the Source or the Mother of Life. This living matter, living substance, or corporeal material has divine attributes. It is conscious, it is aware, and it performs cognitive functions to sustain its own living condition.
THE LAW OF INDIVIDUALITY- HEREDITY AND VARIATION:
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance of Life, Energy, and Knowledge. Identity and Individuality. Two-Sides of the same Coin.The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance. A child is always a created object even when it derives its life from a Mother Cell. Life always comes into existence as a new, original object and displays variation from other members of the same or different species.
Heredity is the sum of all biological processes by which particular characteristics are transmitted from parents to their offspring. A child inherits a genetic constitution from its biological parents. This hereditary endowment, the total of the genes that the child has received from both parents is called the genotype. The genotype of an individual is formed from the constituents of the genotypes of his parents. The genotype in a fertilized Egg Cell influences the developmental pattern of the child. Progeny is not exact duplicates of their parents and usually vary in many traits. Heredity and Variation are two sides of the same coin. The outward appearance of an organism is called the phenotype. The same individual shows different phenotypes in childhood, in adulthood, and in old age. The genotype, on the other hand, does not change during an individual’s life. Each cell in the human body contains the same total genetic information that was present in the fertilized Egg. However, the cells are not identical. In different types of cells, groups of genes are controlled (in effect switched on and off) by various biochemical processes, so that each cell manufactures the proteins and structures needed for it to function. Cells are regulated by the DNA in the nucleus and by the transfer of selected portions of the DNA information to the cytoplasm through the intermediate molecules of ‘Messenger RNA’. It is estimated that, on average, only about 10 percent of the genes of any cell are functional; selection of functional genes varies with the type of cell. This biological phenomenon of selective gene functioning may contribute to what I term as ‘The Law of Individuality’. Deoxyribonucleic acid or DNA accounts for the ability of all living matter to replicate itself exactly and to transmit genetic information from parent to offspring. The child maintains its individuality by selectively switching the inherited DNA on and off. The Law of Individuality applies to all living organisms. Despite the basic biological, chemical, and physical similarities found in all living things, diversity of life exists not only among and between species but also within every natural population.
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance.Despite the basic biological, chemical, and physical similarities found in all Living cells, a Diversity of Life exists within every natural population to establish The Law of Individuality
The Mother Cell is the Source of Life for its child and yet the child comes into existence as a brand new and original product with its own Identity and Individuality. The Mother Cell does not manufacture the new multicellular organism called child. A child is always a created object even when it derives its life from a Mother Cell.
MOTHER – SOURCE OF ENERGY:
Goddess Shakti, a Protector, a Defender, and a Personification of all Material Energies present in Nature or Prakriti. Man exists as an Energy Seeker, a heterotroph and human existence is possible because of an Energy Provider. Mother is the Source of Energy for man’s physical and mental work.Adenosine triphosphate or ATP is a Nucleotide; the monomeric unit of Nucleic Acid,contains a Purine or Nitrogenous base called Adenosine, a Sugar called Ribose and three Phosphate groups.In most Chemical Reactions of all cells in which transfer of energy occurs, the nucleotide ATP is involved. It functions as a Coenzyme in many enzyme-catalyzed reactions and helps in the performance of chemical, electrical, and osmotic work in animals, plants, and microorganisms.
To maintain life an organism not only repairs or replaces (or both) its structures by a constant supply of the materials of which it is composed but also keeps its life processes in operation by a steady supply of energy.
Living systems must be supplied energy for continual synthesis of new organic molecules and to replace or to repair broken organic molecules. This functional activity; the processes of synthesis and breakdown of organic molecules by a living cell, is known as metabolism. Metabolism involves a living system’s continual exchange of some of its materials with its surroundings, principally in the process of building up or destroying its protoplasm. growth involves a higher rate of synthesis of protoplasm than a rate of breakdown of that matter.
ACQUISITION OF ENERGY:
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance.Plant Life acquires useful free energy from the energy of Sunlight and hence described as Photoautotrophs.The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance. Plants are known as Photoautotrophs as they have ability to use free energy from the energy of Sunlight. The Divine Mother is the Source of all Material Energies.The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance. Chloroplasts act like Solar Panels to capture Solar Energy, and all terrestrial life forms depend upon energy from an extraterrestrial or Cosmic Source of Energy.
Organisms acquire energy for their metabolism by two general methods and could be classified as autotrophs or self feeders and heterotrophs or feeders of other organisms. Plants are known as Photoautotrophs as they acquire useful free energy from the energy of Sunlight. In a process known as Photosynthesis, plants use Sunlight to break water into Oxygen and Hydrogen. Hydrogen is then combined with Carbon dioxide to produce such energy-rich molecules as Adenosine triphosphate (ATP) and carbohydrates and the Oxygen is released back into the atmosphere. Humans and most other animals are known as heterotrophs – these organisms acquire energy by the controlled breakdown of pre-existing organic molecules ( food ) supplied by other organisms. Humans utilize the atmospheric Oxygen ( released by plant life ) to combine chemically with organic matter ( food ) they have eaten and release Carbon dioxide and water as waste products. Metabolic processes do not occur in one step. It is not similar to burning sugar in air.
KREB’S TRICARBOXYLIC ACID CYCLE:
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance. Most cells derive their energy from a series of reactions involving Oxygen. In the course of Oxidation, three molecules of energy-rich ATP are generated for each Oxygen atom used to form a molecule of water. The Mitochondria is the cellular site of this respiratory Combustion.
The glucose, a simple sugar is broken down by a series of successive and coordinated steps, each mediated by a particular and specific enzyme. The human organism extracts useful energy by a metabolic process described as Oxidation-Reduction Reactions. The glucose is broken down in a series of about 71 enzymatically catalyzed steps. The first 11 of these biochemical reactions do not involve the use of Oxygen. These Oxidation-Reduction Reactions occur in intracellular organelles known as Mitochondria in the cytoplasm of cells.
MITOCHONDRIA – THE POWERHOUSE OF CELLS:
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance.In Mitochondria, many substances are oxidized and ATP, the energy-storing chemical of the cell is produced. This energy is utilized in a variety of cellular functions and activities.
Mitochondria are typically sausage-shaped particles about 0.5 to one micron wide and about 5 to 10 microns long. They are surrounded by an outer unit membrane which controls the passage of material into and out of the mitochondria and govern their internal environment. The inner membrane is the site of the respiratory functions that make the mitochondria the so-called Powerhouse of the Cell. The inner membrane is folded repeatedly into shelf like folds called cristae which contain the enzymes that play an essential role in conversion of the energy of foodstuffs into the energy used for cellular activities.
MITOCHONDRIA AND CHLOROPLASTS – A DIVINE SOURCE FOR ENERGY ACQUISITION:
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance. Both Mitochondria and the Chloroplasts are semi-independent and self-reproducing parts of the Living Cells. It is a Divine Mechanism to provide Energy for Metabolism the characteristic of Living Matter.The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance.The Mitochondria have a degree of “AUTONOMY” and they are unlike the other components of cells.
Mitochondria and Chloroplasts found in the green plant cells perform the same fundamental processes. The Chloroplasts contain the green colored pigment known as Chlorophyll. The Chloroplasts convert the energy of Sunlight into energy-rich ATP and use ATP to convert Carbon into specific organic substances. The most important equations for living things are mutually inverse. Respiration of human organisms represents the reverse of Photosynthesis of Green Plants. Both Mitochondria and the Chloroplasts are semi-independent and self-reproducing parts of the living cells. They have a degree of autonomy and they are unlike the other components of cells. Mitochondria contain DNA in the form of a Chromosome arranged in a ring. The DNA of Mitochondria has different distribution of bases from that of the DNA found in the Chromosomes present in the nucleus. Mitochondria carry the genes for their own replication and for the enzymes found in them. They can synthesize some of their own proteins and reproduce by themselves. In one respect the mitochondria function as the parts of the cells and in another respect, they behave like independent organisms that reproduce on their own.
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance. A group of Mitochondria – Computer artwork. Who has “Designed” the Mitochondria? Do they represent a Divine Mechanism to provide Energy to Energy Dependent Living Organisms?
The Mother Cell is the source of Mitochondria found in all the cells of my human body. During the Growth and Development of Human Embryo and Fetus, all the newly formed cells contain Mitochondria derived from the Egg Cell. Hence, mother as a biological parent represents the Source of Energy for all the Living Functions and activities of her children. I cannot move a muscle in my body without drawing energy supplied by the maternal Mitochondria which continue to live and replicate establishing my mother as the Source of Energy for my existence during my entire Life’s Journey.
MOTHER – SOURCE OF KNOWLEDGE:
Goddess Sarasvati is the Divine Mother of Knowledge. Indian Tradition recognizes Mind, and Intellect as aspects of Material Energies. Life functions with Knowledge implanted into Living Organisms which display the characteristics of awareness, responsiveness, alertness, and consciousness.What is Life? Life is Knowledge in Action. A living cell performs a variety of functions that are characteristic of its life. The Cell Structure known as Nucleus is the Seat of Knowledge. In structures known as Chromosomes it stores hereditary, and biological information for its growth, development, replication, reproduction, and metabolic functions such as protein synthesis for its growth and maintenance. Protein Synthesis takes place in structures known as Ribosomes that are located in Cytoplasm outside the Nucleus. Nucleus transfers information to Ribosomes by using Transfer RNA. Nucleus provides only information and to use that information for its function of Protein Synthesis, the Ribosome derives Energy from another Cell Structure known as Mitochondrion. This process of Cellular Function describes Knowledge in Action.
Life is the state of an individual characterized by the capacity to perform certain functional activities including the ability of responsiveness. Life is further characterized by presence of complex transformation of organic molecules and by organization of such molecules into the successively larger units of protoplasm, cells, organs, and tissues. Hence, I have defined Life as “Knowledge in Action.”
Responsiveness represents the ability of an organism to change in response to alteration in its environment. Responsiveness, alertness, awareness, and consciousness separates living from nonliving matter and defines life’s underlying principle. Living cells are aware or conscious of the environment in which they exist as well as the state of their own internal environment. The one very important part of environment of a cell is other cells. The ability called awareness and responsiveness is important for recognition, association, and cooperation between cells. Cells function together by exchanging chemical signals.
THE BIOLOGICAL MEMBRANE – AN ORGAN OF SENSE PERCEPTION:
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance.The Biological Membrane or Plasma Membrane functions like an Organ of Sense Perception and it maintains cell’s internal environment and establishes contact with cell’s external environment.
Cell is the most elementary unit of Life. Cell is bounded by a Plasma Membrane which is more correctly described as a Biological Membrane. It separates the cell from the environment and from other cells. It helps to maintain a constant milieu in which intracellular reactions occur. The Biological Membrane allows a highly controlled exchange of matter across the barrier it poses, some compounds are able to pass through the membrane easily, others are blocked. Cells contain various internal structures such as the nucleus, and mitochondria, each of which is enclosed by a Membrane. Both the Biological Membrane and some of the intracellular membranes are parts of a continuous Membrane System that extends through much of the body of the cell. It serves two purposes. A compartmentalization of cell is required for many cellular activities, including uptake and conversion of nutrients, synthesis of new molecules, production of energy, transportation, and release of cell products, and regulation and coordination of metabolic sequences. The cellular organelles are protected from one another’s enzymatic activities, and those of the cytoplasm. The Biological Membrane System functions like an Organ of Sense Perception and maintains the responsiveness of the cell.
THE CYTOPLASMIC OR MATERNAL INHERITANCE:
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance.Mitochondria areinherited from maternal cytoplasm.
Deoxyribonucleic acid or DNA accounts for the ability of all living matter to replicate itself exactly and to transmit genetic information from parent to offspring. While offspring inherit a genetic constitution and hereditary traits from both parents, some characteristics are inherited through the maternal line only. For example, there are no Chlorophyll containing Chloroplasts in pollen grains of (male) flowers. The act of Pollination does not contribute this most important characteristic known as Chloroplasts. Chloroplasts are found only in the Egg Cells of (female) flowers. Similarly, humans inherit the Powerhouses called Mitochondria only from Maternal cytoplasm. A Cytoplasmic Inheritance is entirely Maternal. Human functions that involve Sensory Perception, Mental Cognition, Learning, and the functions of Memory and Consciousness should be viewed as functions of the cytoplasm. Cytoplasm represents the Seat of Knowledge. Man begins Life as a single cell with its cytoplasm and cell membrane. The cell grows and divides while building more of its cytoplasm. Knowledge is the Fact of Knowing, the State of Knowing, and the Act of Knowing a range of information. The Mother or the Source of Knowledge is the Maternal Cytoplasm and the Cell Membrane inherited from the Egg Cell, Ovum, or the Mother Cell.
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance.
Rudolf is reborn as Rudi to describe the spiritual connection between the Cell and its Energy Provider
Rudolf is reborn as Rudi to describe the spiritual connection between Cell and its Energy Provider.
Rudi acknowledges his German heritage at Whole Foods when he discovered the spiritual connection between man, food, and Providence. Whole Foods, Whole People, and Whole Planet are connected by a material substance called Protoplasm, a divine plan to provide nourishment to Life.
The Rudolf and Rudi Connection. The Discovery of Whole Spirituality at Whole Foods, Ann Arbor.
The Rudolf and Rudi Connection at Whole Foods, Ann Arbor can be best described as the concept of Whole Spirituality, the three dimensional spiritual relationship between the multicellular human organism, food, and the Divine Providence.
Rudolf is reborn as Rudi to describe the spiritual connection between Cell and its Energy Provider. The 3-Dimensional Spiritual Relationship between Man, Food, and God.
SPIRITUALISM – THE CELL THEORY OF SPIRITUALITY:
The Rudolf and Rudi Connection. The Discovery of Whole Spirituality at Whole Foods, Ann Arbor.
In Biology, cell is the basic or fundamental unit of structure, function, and organization in all living things or it is the building block of life. Let me begin with my respectful tribute to some of the people who contributed to ‘The Cell Theory’, one of the foundations of Biological Sciences. Cells were first observed in the 17th century shortly after the discovery of the microscope. Robert Hooke, british curator of instruments at The Royal Society of London, during 1665 coined the word cell. Dutch microscopist Antonie Van Leeuwenhoek (1632-1723) made over 247 microscopes and examined microorganisms and tissue samples. He gave the first complete descriptions of bacteria, protozoa (which he called animalcules), spermatozoa, and striped muscle. He also studied capillary circulation and observed Red Blood Cells.
Robert Hooke, british curator of instruments at The Royal Society of London coined the term cell during 1665.Dutch microscopist Antonie Van Leeuwenhoek (1668-80) studied capillary circulation and observed Red Blood Cells
Improvements in microscopy during early 19th century permitted closer observation and the significance of cells had received better understanding. Matthias Jakob Schleiden (1838), german botanist, Theodor Schwann (1839), german physiologist, and Rudolf Virchow (1855), german pathologist, and others made important contributions to the Cell Theory that describes cell as the building block of all Life.
Schleiden, Professor of Botany, The University of Jena studied plant structure under the microscope, published “Contibutions to Phytogenesis”(1838). He had also published the two-volume text of ‘Principles of Scientific Botany’.Schwann founder of modern Histology extended the Cell Theory of Plants to animals in his ‘Microscopic Researches into Accordance in the Structure and Growth of Animals and Plants(1839).Schwann discovered Myelin Sheath covering peripheral axons, now termed Schwann Cells. He coined the term ‘Metabolism’ for the chemical changes that take place in living tissues.Rudolf Virchow,german pathologist in 1855 coined the biological dictum “OMNIS CELLULA E CELLULA” – All living cells arise only from pre-existing living cells.
The Cell is the smallest unit in the living organism that is capable of carrying on the essential life processes of sustaining metabolism for producing energy and reproducing. Many simple, small, single-celled organisms like Protozoa perform all life functions. In higher, complex, bigger, multicellular organisms, groups of cells are structurally and functionally differentiated into specialized tissues and organ systems. Thus, the Cell Theory includes the following foundational principles of the Biological Sciences:
1. All living things are made up of cells. Cell is the most elementary or basic unit of Life.
2. Cell is a fundamental unit of structure, function, and organization in all living things including plants and animals.
3. Cells only rise from division of previously existing cells.
4. All cells are similar in composition, form, and function. All cells are basically the same in chemical composition (in spite of variations) in organisms of similar species. For example, all the solid tissues in the human body can be shown to consist largely of similar cells; differing it is true, but that are essentially similar to an Ovum.
5. The cells exhibit functional autonomy. The activity of an organism depends on the total activity of ‘INDEPENDENT’ cells.
6. Energy flow (metabolism and biochemistry) occurs within cells.
7. Cells contain hereditary, biological information (DNA) which is passed from cell to cell during cell division.
THE CELL THEORY OF SPIRITUALITY:
The Rudolf and Rudi Connection. The Discovery of Whole Spirituality at Whole Foods, Ann Arbor.
The basic or fundamental unit of life in the human organism is derived from the fertilized egg cell that eventually develops into a complete organism. The most significant feature of similarity between the cells of the human body is the presence of a soft, gelatinous, semi-fluid, granular material inside the cell. This substance known as Protoplasm or Cytoplasm, or Cytosol is similar to the ground substance found in the Ovum or the Egg Cell.
Human Ovum Structure – The Cell Theory of Spirituality is based upon the Substance, Structure, Form, Organization, Function, Action and Interactions of this Single Fertilized Egg Cell that eventually develops into a complete human organism.
This viscous, translucent, colloidal substance is enclosed in a membrane called Cell Membrane, Plasma Membrane or Biological Membrane. A small spherical body called nucleus is embedded in the Protoplasm of the cell. The three essential features of any living cell in the human body are that of the presence of protoplasm, the nucleus, and the cell membrane.
PROTOPLASM – THE GROUND SUBSTANCE OF SPIRITUALISM AND SPIRITUALITY:
I seek the existence of Soul or Spirit in a substance that is basic to life activities, and in a material that is responsible for all living processes. I, therefore, propose that the understanding of the true or real nature of this ground substance of all living matter will help man to discover peace, harmony, and tranquility in all of his internal and external relationships while man exists in a physical environment as a member of a social group, social community, and Society. In this blog post, I would like to pay my respectful tribute to Jan Evangelista Purkinje and Hugo Von Mohl for their great contribution to the scientific understanding of the living substance, living material, and living matter.
Jan Evangelista Purkyne(Czech name), Jan Evangelista Purkinje(German name)also known as Johannes Evangelist Purkinje, b. December 17, 1787, d. July 28, 1869. The pioneer Czech experimental Physiologist whose investigations in the fields of Histology, Embryology,and Pharmacology helped create a modern understanding of the eye and vision, brain and heart function, mammalian reproduction, and the composition of cells.
Purkinje conducted his research on human vision at the University of Prague and later on, he served there as a Professor of Physiology (1850-69). He went to Germany and was appointed the Chair of Physiology and Pathology (1823-50) at the University of Breslau, Prussia. There Purkinje created the world’s first independent Department of Physiology (1839) and the first Physiological Laboratory (Physiological Institute, 1842). He is best known for his discovery of large nerve cells with many branching extensions found in the cortex of Cerebellum of the brain (Purkinje Cells, 1837). He discovered the fibrous tissue that conducts electrical impulses from the ‘pacemaker’ called Atrioventricular node or A-V node along the inside walls of the ventricles to all parts of the heart to help in Cardiac contractile function (Purkinje Fibers, 1839). In 1835, he invented and introduced the scientific term ‘Protoplasm’ to describe the ground substance found inside young animal embryo cells. He discovered the sweat glands of the skin (1833); he discovered the nine configuration groups of Fingerprints used in biometric identification of man (1823); he described the germinal vesicle or nucleus of the unripe ovum that now bears his name (1825), and he noted the protein digesting power of pancreatic extracts (1836).
Hugo Von Mohl, b. April 08, 1805, d. April 01, 1872, German Botanist noted for his research on the anatomy and physiology of plant cells.
Hugo Von Mohl named the granular, colloidal material that made up the main substance of the plant cell as “Protoplasm” in 1846. Purkinje invented the word, but Hugo gave more clarity, understanding, and knowing the nature of this ground substance. He viewed cell as an “elementary organ” and in Physiology he explained Protoplasm as an organ of Motion or Movement, Nutrition, and Reproduction. It is the preliminary material in cellular generation. He was the first to propose that new cells are formed by division of preexisting cells and he had observed this process of Cell Division in the algal cells of Conferva glomerata. His observations are very important to understand the Cell Theory that explains cells as the basic building blocks of Life. He was the first to investigate the phenomenon of the stomatal openings in leaves.
The Ground Substance of Spiritualism and Spirituality. The vital characteristics, the animating principles of Protoplasm could be known by observing Amoeba proteus. The Living Substance works as an organ of Motion or Movement, as an organ of Nutrition, and as an organ of Reproduction to generate new cells which have a life span of their own. In these physiological functions, I describe the characteristics such as Cognition, Consciousness, Memory, and Intelligence which have a Spiritual role as they bring functional unity and harmony in the interactions between different parts of the same individual organism while it exists in an environment as a member of a biological community.
Protoplasm is a complex, viscous, translucent solution of such materials as salts and simple sugars with other molecules, mostly proteins and fats, in a colloidal state, that is dispersed but not dissolved in one another. Carbon, Hydrogen, Oxygen, and Nitrogen constitute more than 90 percent of Protoplasm. It exhibits properties such as Protoplasmic Streaming or Cytoplasmic Streaming or Motion that is called “Amoeboid Movement.” It has the intrinsic power to change its shape and position. It has the power of Nutrition by which it can attract and obtain the materials necessary for its growth and maintenance from surrounding matter/environment. These functions involve acquiring, processing, retaining, and using information to perform tasks in a sequential manner for a predetermined purpose and hence describe Consciousness, Memory, and Intelligence. The terms Soul and Spirit belong to the materialistic realm where the Physical Reality of man’s biological existence is established. I have not yet discovered any good reason to use the terms Soul and Spirit as a metaphysical or transcendental Reality.
The Ground Substance of Spiritualism and Spirituality. The vital characteristics, the animating principles of Protoplasm could be known by observing Amoeba proteus. The Living Substance works as an organ of Motion or Movement, as an organ of Nutrition, and as an organ of Reproduction to generate new cells which have a life span of their own. In these physiological functions, I describe the characteristics such as Cognition, Consciousness, Memory, and Intelligence as spiritual attributes of Life as they bring functional unity and harmony in the interactions between different parts of the same individual organism while it exists in an environment as a member of a biological community.
THE SPIRITUALITY OF SUBSTANCE, FUNCTION, ORGANIZATION, ACTION, AND INTERACTIONS:
The Rudolf and Rudi Connection. The Discovery of Whole Spirituality at Whole Foods, Ann Arbor.
To establish the biological existence of the human organism, I add the concept of Spiritualism and Spirituality to the Cell Theory. The Single Fertilized Egg Cell has ground substance that is of Spiritual nature and the Spiritualism and Spirituality consists of the following functional, and organizational characteristics:
The Rudolf-Rudi Connection at Whole Foods. The Concept of Whole Inheritance. Spirituality Science. What do you do for Living? THE PROCESS, THE MECHANISM CALLED CELLULAR RESPIRATION IS NOT LEARNED OR ACQUIRED EXPERIENCE. NO SPIRITUAL TEACHER, NO SPIRITUAL MASTER, AND NO SPIRITUAL GUIDE CAN IMPLANT THIS KNOWLEDGE IN MAN.
1. The Cell is Conscious of its own existence and knows its internal condition and knows it external environment.
2. The Cell is intelligent and it has the cognitive abilities like perception and memory to acquire information, to retain information, to recall information, and to use information in the performance of its complex tasks in a sequential manner.
3. The Cell has the ability to show characteristics such as mutual cooperation, mutual tolerance, and display functional subordination and subservience while being independent.
4. The Cell grows, divides, and develops into a complete organism while it acquires substances and energy from an external environment. The power of Protoplasm/Cytoplasm to attract matter found in its external environment is called Nutrition. The Cell continuously transforms matter to build matter of its own kind for its own benefit to sustain its existence with its own identity and individuality. The Organism represents a social group or a biological community of Cells. The Spiritual nature of Protoplasm/Cytoplasm brings this functional harmony and unity in the Social Group or Biotic Community of Cells by bringing together its Essence and Existence.
5. The Cell Theory is incomplete for it does not describe the conditioned nature of the Cell’s existence. The Cell represents a Living System that is thermodynamically unstable. It requires a constant supply of matter and energy from its external environment to sustain its living functions. The concept of Whole Spirituality formulates the connection between the Cell and its external source of matter and energy.
The Rudolf and Rudi Connection. The Discovery of Whole Spirituality at Whole Foods, Ann Arbor. The Bone Marrow smear from a patient of Leukemia or Blood Cancer helps to illustrate the nature of Biotic Interactions in the Social Group or Biotic Community that represents the singularity called man. The true or real man can only be discovered by the microscopic study of the Cells that constitute the Organism.
The theoretical claims about Spirit and Soul, the religious and philosophical doctrines of Spiritualism and Spirituality must be verified using the Cell Theory that defines the human organism. To describe Soul or Spirit as nonmaterial or immaterial Self will not help man to know the real or true man.
The Rudolf and Rudi Connection. The Discovery of Whole Spirituality at Whole Foods, Ann Arbor.
Whole Foods, Whole People, and Whole Planet come together in a Wholesome Relationship as God is the Energy Provider, the Original Source of Matter and Energy for Life.
Rudolf is Reborn as Rudi to describe the spiritual connection between the Cell and its Energy Provider. THE LIVING CELL IS THERMODYNAMICALLY UNSTABLE. TO EXIST, THE LIVING CELL NEEDS CONTINUOUS SUPPLY OF MATTER AND ENERGY FROM ITS EXTERNAL ENVIRONMENT. PROTOPLASM OR CYTOPLASM USES THE POWER OF NUTRITION TO ACQUIRE MATTER AND ENERGY FROM ITS EXTERNAL ENVIRONMENT AND ENABLES THE LIVING CELL TO PERFORM A VARIETY OF LIVING FUNCTIONS CALLED METABOLISM.The Rudi Connection at Whole Foods joins the Maha Navratri Celebration of the Divine Mother.
In my analysis, there can be no ‘Theory of Health’ without sharing ‘Theory of Man’. The question, “What is health?” cannot be asked without raising the question, “What is man?”
In my view, ‘existence of man always precedes essence of man’. For that reason, biological basis of man’s existence must be identified to define living entity called man.
Man’s existence in any condition, good health or ill health, at any age, at any given time and place, depends upon Mercy, Grace, and Compassion( Sanskrit. KRUPA or KRIPA) of LORD God Creator. Man does not exist in Natural World because of his physical and mental work. Man needs input of matter and energy, from an external source, from the moment of conception until conclusion of his entire life journey. Man’s existence is always conditioned as he cannot regulate either internal, or external factors that determine the fact of his existence.
I invite my readers to review article titled “What is health?” published in Microbial Biotechnology by Dr. Harald Brüssow. I took freedom to add few comments to his article to help my readers to examine the topic in a critical manner.
This article has been cited by other articles in PMC.
Summary
Medical Science fails to define the term ‘health’ for it fails to define the term ‘man’. To attach meaning to health, I must attach meaning to word called ‘man’.
Classical medical research is disease focused and still defines health as absence of disease. Languages, however, associate a positive concept of wholeness with health as does the WHO health definition. Newer medical health definitions emphasize the capacity to adapt to changing external and internal circumstances. The results of the 2010 Global Burden of Disease study provides keys for a quantifiable health metrics by developing statistical tools calculating healthy life expectancy. Of central social and economic importance is the question whether healthy ageing can be achieved. This concept hinges on theories on the biological basis of lifespan determination and whether negligible senescence and the compression of morbidity can be achieved in human societies. Since the health impact of the human gut microbiome is currently a topical research area, microbiologists should be aware of the problems in defining health.
Introduction
Man represents biological community of trillions of individuals; independent, living cells with individuality. Man is also natural host to trillions of microbes. Human life must be defined in terms of biotic interactions; both intraspecific, and interspecific biotic interactions.
Science has its fashions. Suddenly the leading science journals are full of articles about a specific topical research area. Sometimes, this wave of popularity follows a technological break-through which permits asking questions that were previously impossible to tackle or at least very hard to address experimentally. At other occasions, this cumulating of top-level research reports is the consequence of large international research efforts where grant agencies provided large amounts of money, which attracted many scientists to the field. In still other situations, the scientific community realizes that a certain field of scientific inquiry has simply been overlooked or neglected and the view offered by the new insights is exiting theoretical interest and promising practical applications. The human microbiome is currently such a fashionable field. Novel DNA sequencing techniques combined with new bioinformatic tools and the general progress of ‘–omics’ technologies offer the methods; major research grants on both sides of the Atlantic provided the money and the field has been an eye-opener for microbiologists which might be compared with the time of Leeuwenhoek when microbes in our mouth were first seen in the microscope and the time of Koch when the first isolated bacterial colonies were seen by the naked eye and linked to human disease. We perceive the human microbiome metagenome as our second human genome, as a source of human genetic variability (Schloissnig etal., 2013) and as a factor influencing human health (Clemente etal., 2012). The human gut microbiome has been associated with health issues of central importance such as obesity (Turnbaugh etal., 2006), healthy ageing (Claesson etal., 2012) and most recently cancer (Arthur etal., 2012), to quote only the most prominent fields. Probiotic bacteria have also been fashionable for a while (Thomas etal., 2010) and were judged to have a scientific basis (Neish, 2009), but scientific reports aroused less attention than gut microbiota research. Probiotics carry in their definition as ‘live health-promoting bacteria’ the concept that microbes can influence our health. But what is health? If you want to boost health, you must know what it is and how to measure it.
Health: ask the experts
I ask Medical Science to apply principles of Clinical Medicine not only to diagnose ill health but also to diagnose good and perfect or ‘Whole Health’ for man is created by entity called God who is always Perfect and Whole.
At school we heard of Socrates who asked people who are supposed to be experts and to get an answer from a dialogue with them. Therefore, I first went to health authorities like medical doctors and their authoritative textbooks that guided generations of medical students like Harrison’s Principles of Internal Medicine (Longo etal., 2011). In the 18th edition you find ample material on pathogens, even a chapter on the human microbiome (Gordon and Knight, 2011), a chapter on women’s health, but no definition of health. Overall, one gets the impression that medicine deals with disease and not health. In a recent meeting, one of my colleagues said that the US National Institutes of Health (NIH) should correctly be called National Institutes of Diseases reflecting this disease focus of medical research. Health is currently fashionable as ‘Global Health’, but again scientists working at institutes called like this or in such programmes deal mostly with diseases. After this disappointment, the author turned to PubMed with ‘health’ and ‘definition’ as search terms and got less than 20 papers – a quite surprising outcome for such a central question of the human society. Clearly there is a problem with the definition of the term ‘health’.
Health: ask the languages
None of the living functions performed by man involve the use of any known human language.
When a term is so self-evident and at the same time so elusive that no definition is provided in the scientific literature, it is frequently helpful to investigate the words we use when speaking about it. Naming is the first activity of human beings when trying to make order of things surrounding us. Words reflect the experience of many generations and words constitute a collective subconsciousness that determines still today our unexpressed thoughts and actions, more than we are aware of consciously. In the Oxford Dictionary ‘health’ is defined as ‘the state of being free from illness and injury’. It is obviously a negative definition. Such a definition reflects the current use of the words in the spoken language, but not necessarily its development over time. The English ‘health’ derives from Old English ‘hælth’, which is related to ‘whole’ ‘a thing that is complete in itself’ (Oxford Dictionary) derived from Old English ‘hal’ of Germanic origin (the addition of the w in whole/hal reflects a dialect pronunciation of the 15th century). In Middle English ‘hal’ also became ‘hail’ with the meaning of health in greetings and toasts. ‘hal’ is related to the Dutch ‘heel’ and the German ‘heil’. In German the connections between health, wholeness and salvation becomes even clearer than in English. ‘Heil-kunde’ and ‘Heil-kunst’ are still common German words for medicine, ‘Heiler’ is a traditional or alternative health provider; ‘heilfroh’ means wholly happy and refers to a relationship between health and happiness. ‘Heil’ has also religious meanings as seen from the German word ‘Heiland’ for the Christ as Savior (or for false prophets as in ‘Heil Hitler’). The German word conserved clear links with the religious and cultic realm in ‘heilig’ (English: holy) where ‘Heil’ is equivalent with salvation in the religious meaning (‘Seelen-heil’). These connotations are still vibrating consciously or unconsciously in native speakers when using these words. In fact, from this quasi-religious context the constitution of the WHO adopted in 1948 becomes understandable when stating ‘the following principles are basic to the happiness, harmonious relations and security of all peoples: Health is a state of complete physical, mental and social wellbeing and not merely the absence of disease or infirmity’. The definition has not been revised but was variously challenged for its ‘complete wellbeing’ as reflecting a fundamentalist view, referring to an ideal world of messianic expectations. Some scientists have therefore asked for redefining health to make it a realistic, measurable quantity (Saracci, 1997).
Since this language approach turned out to be revealing, let’s follow the relationship between health and wellness (are they synonyms or do they express distinct concepts?) and between health and disease (are they antonyms?). Disease is defined by the Oxford Dictionary as ‘disorder of structure or function in an organism that produces specific symptoms and is not the result of physical injury’; ‘dis-ease’ derives from the Old French ‘desaise’ (lack of ease). Wellness and illness is clearly a pair of antonyms. Illr is a Norse word for evil and was taken into Middle English with the meaning of wicked, malevolent. ‘Well’ (German: wohl) derives from a word common to many Germanic languages and means ‘in a good way’, initially as a contrast to wicked. As an adjective one of the meaning of ‘well’ is specifically ‘in good health’ (Oxford Dictionary). In German ‘wohl’ goes beyond good health, it alludes to psychological and emotional aspects (‘Wollust’: English: lust, but in Old English as in current German still in the sense of ‘pleasure’ and ‘delight’) and material wealth (‘Wohlstand’). Wellness thus goes beyond physical health and has a strong connotation of happiness, but also of hedonism (where pleasure is the chief good).
One might argue that these are linguistic associations restricted to Germanic languages. However, this is not the case: the Latin word pair ‘salus’–’malus’ has very similar connotations which were transmitted into modern Romanic languages (French: salut–maladie). In Latin ‘salus’ means health, rescue, redemption and wealth. It derives from ‘salvus’, Old Indian ‘sarvas’, which meant initially nothing else than ‘whole’. We see here again the notion of completeness with health. Malus which leads then to malady shares with the Germanic word ‘small’ a common root and thus refers to incompleteness. Malus has also moral connotation (Eritis sicut deus scientes bonum et malum – the snake in Genesis: you will be like God knowing the good and the evil). Disease has long been regarded as a celestial punishment for moral failing. In many traditional societies, health surveys should not miss to ask about ‘the evil eye’, underlining the widespread magic concepts on disease.
Redefining health: medical approaches
What is Spiritual Sickness? Lust, Avarice, Anger, Arrogance, Jealousy, Infatuation, and Miserliness are symptoms of Spiritual Sickness. Spiritual well-being is integral component of Whole Health.
Recently the need for a new definition of health was expressed by the British Medical Journal (Jadad and O’Grady, 2008). A discussion via global blog conversation was initiated on ‘How should health be defined?’ The participation rate was weak: only 38 communications were counted. In an influential blog, R. Smith (2008) confessed that this issue is for most doctors an uninteresting question since they are interested in disease and not health. Medical textbooks are a massive catalogue of diseases. Health is an illusion and according to the strict standards of the WHO definition, most people are unhealthy for most of the time, so far, his comments. Research-oriented doctors complained that the WHO definition has no direct operational value – it is so widely formulated that health outcome cannot easily be measured. Health like beauty is in the eyes of the beholder. It turned out that redefining health is an extremely ambitious and complex goal. A conference held in 2009 in the Netherlands (‘Is health a state or an ability? Towards a dynamic concept of health’) (Huber, 2010), an editorial by the Lancet (‘What is health? The ability to adapt’) (Anonymous, 2009) and an analysis in the BMJ (‘Health: how should we define it?’) (Huber etal., 2011) proposed a few conclusions. The preferred view on health was the ability to adapt and to self-manage. With respect to physical health the term of ‘allostasis’ was introduced – the maintenance of physiological homeostasis through changing circumstances. In the field of mental health, a sense of coherence was identified as defining criterion. Social health included people’s capacity to fulfil their potentials and obligations, the ability to manage their life and to participate in social activities including work. R. Smith summarized this into the phrase ‘health is the capacity to love and work’ attributed to Sigmund Freud. The Dutch conference highlighted a few important aspects. When applied to ‘successful or healthy ageing’ only a very small percentage of people would fit the WHO definition. When self-rating of well-being was used a much higher percentage rated themselves as successfully ageing and this rating was roughly constant over lifetime. With an ageing population chronic disease become a life condition to many people. The Stanford Chronic Disease Self-Management Programme uses strategies to enhance self-efficacy which resulted in fewer healthcare requests. Also, the WHO has added to this discussion. In preparation of the Ottawa Charter of 1986, the WHO defined health as the ability of an individual to realize aspirations and satisfy needs and to cope with the environment. Health was thus seen as a resource for everyday life. The WHO has also developed an International Classification of Functioning, Disability and Health assessing the performance of a task in real life situation. WHO surveys assessed an individual’s health state by asking for mobility, self-care, pain, cognition, interpersonal activities, vision, sleep and energy and affect. The answers go into a single metric reaching from death (0) to perfect health (1). The abovementioned Lancet editorial quoted the French physician G. Canguilhem who perceived health in his 1943 book The Normal and the Pathological not as something that can be defined statistically or mechanistically. Health is the ability to adapt to one’s environment and its own limitations. At the Dutch conference, a participant asked for the concept of ‘salutogenesis’ (becoming healthy) and more concrete research work in a field dominated by studies of pathogenesis (becoming ill). In practical terms it means that instead of carefully observing the conditions that lead from the healthy to the diseased state, research should also be conducted for the opposite process, i.e. the transition from the diseased to the healthy state. In some diseases the transition from health to malady is a way of no return and its inverse process of ‘salutogenesis’ is obviously difficult to study. However, for microbiologists the situation is easier. Many acute infectious diseases show a transition from health to disease followed by a return to the normal. Here ‘salutogenesis’ is commonly studied and had practical outcomes. For example, understanding the immune response to an infectious agent which led to the resolution of the disease was often instrumental for designing vaccine strategies.
Scaling health levels?
Scaling of health fundamentally relates to experience of satiation, satisfaction, or contentment from living condition. Dissatisfaction or lack of contentment is absence of health.
A fundamental question not yet addressed in our discussion is whether health is a state as opposed to the alternative state of disease. There are medical conditions that allow only two alternative conditions; a frequently quoted example is a woman in childbearing age who either is pregnant or is not pregnant. There is no condition where a woman is a bit pregnant, pregnancy is an all-or-nothing event allowing only a ‘plus’ and a ‘minus’ state and no transitions between both of them. At first glance, one might also take ‘health’ and ‘disease’ as alternative ‘plus’ and ‘minus’ states. The self-perception of a subject is a relative reliable measure differentiating a healthy state from a diseased state. In a prodromal phase of an infectious disease, we feel lousy before any overt disease symptoms are evident. During convalescence we feel the reverse process of returning vigor and strength. This distinction finds expression in our outer appearance allowing not only an experienced physician, but even an attentive layperson to differentiate these two states with a single look at a person. This experience speaks for health and disease as two alternative states. However, medical doctors use scoring systems to assess the health and disease status of patients to decide on medical interventions. To quote just two examples: the Karnofsky score runs from 100 (perfect health) to 0 (death) in steps of 10 and assesses the independence or dependence of patients on assistance for everyday activity or survival; its main purpose was to quantify the capacity of cancer patients to cope with chemotherapy. Another score rates the status of newborns: the Apgar score attributes up to two points each for the appearance, pulse, grimace, activity, respiration of the baby (despite this mnemonic, Apgar is named after an anesthesiologist). Apgar expresses the need for medical intervention by the pediatrician. Apgar scores of 7 or higher characterize healthy babies. These scoring systems are interesting since first, they put health and disease into the same measurable category and second, they anticipate that both health and disease states can be graded. By their design as indicators for medical intervention, these scoring systems have more graded disease levels than graded health levels, but this point can be quickly remedied by introducing a scoring system that depicts in analogy with the number line increasing positive integers to the right as indicators of a graded health level and increasing negative integers to the left as indicators of graded disease levels.
Around 0 is an indifference zone where the subject feels neither particularly healthy nor definitively ill. While numerous scoring systems exist to describe severity grades for many diseases, less scoring systems exist for assessing health levels. This situation could quickly be corrected: Physical strength or mental fitness could be measured quantitatively by performance tests on the subject or functional reserves could be measured by physiological tests on individual organ systems of the subject. Such physical types of test are frequently used in geriatric medicine.
This grading concept – oversimplified as it is – has interesting consequences. When physicians speak about health interventions, they speak mostly about disease interventions where a treatment shifts for example a person from disease level −7 to disease level −3 to remain in the analogy of this fictive scale. Over recent decades medical treatments were also increasingly applied on apparently healthy subjects, who show, but do not suffer, from pathophysiological states (e.g. hypertension, hypercholesterolemia) in order to prevent for example a shift from health level +3 to disease level −7 when the pathophysiological risk factor transforms into actual disease (e.g. myocardial infarct or stroke) (again in this fictive scale). However, physicians and the pharmaceutical industries have much less considered the possibility to increase health levels from for example health state +4 to health state +7 which increases physical and mental performance of the person or the functional reserves of the person’s organs. These health interventions were largely left to fitness centers and sport clubs and private activities of the individual. The aim of such nutrition and health interventions would be a better performance in everyday life, more pleasure (quality of life), but not necessarily disease prevention. However, increasing the functional reserve of the body necessarily creates a buffer such that extrinsic factors decreasing the health level do not result that quickly in disease as without this intervention.
Health: ask the Global Burden of Disease (GBD) 2010 survey
Burden of Disease, and Rewards of Health must be estimated after stating Purpose of Human Existence.
One might argue that health of an individual or a population is to a certain extent a lip service of the medical profession and the true interest of medical doctors is to cure or to prevent disease. Language-wise this focus is expressed by the now frequently used term of ‘ill health’ in the columns of leading journals like ‘Nature’ and ‘The Lancet’, which is of course a clear contradiction in terms and reflects the disease focus of medicine. One might suspect that economists and sociologists have a greater interest in the health of a population when focusing on the productivity and social ‘functioning’ of people. However, such an evaluation does not do justice to the epidemiological, statistical and intellectual efforts of the medical community to come to grip with these terms. The Herculean effort of the medical research field is illustrated by a whole issue of the Lancet describing the GBD Study 2010 in a series of articles (Das, 2012). Over 5 years 486 scientists from 302 institutions in 50 countries have collected data on ‘ill health’ and evaluated the data by using the most sophisticated statistical data treatment methods (Murray etal., 2012a). The results are stunning. It is here not the place to review these studies, but I want to share with the reader some excitement. From 1970 to 2010 global life expectancy at birth rose by 3–4 years every decade. The resolution of the data set is astonishing: you can for example compare life expectancy per region and per sex. You see then that women in Bangladesh increased their life expectancy from 47.5 years in 1970 to 71.0 years in 2010 (not a printing error). Or you get global life expectancy per 5-year intervals for both sexes, e.g. 80-year-old men had in 1970 a life expectancy of 5.8 years compared with 7.2 years in 2010 (‘the older you get, the healthier you have been’) (Wang etal., 2012). Or you get information on 235 leading causes of death separated by age and sex based on files compiling vital registrations, verbal autopsies and various surveillance data from 187 countries. You learn that mortality from communicable diseases has decreased over this time following major ameliorations in mortality from diarrheal diseases, measles and tetanus, but less so for respiratory infections and increases for HIV/AIDS. When the global years of life lost (YLL) is displayed separately for the causes and individual years between 1990 and 2010, the data analysis was so well performed that you see the 1995 famine in North Korea as a sudden increase in global death due to nutritional deficiencies and the 1994 genocide in Rwanda as an intentional injuries increase (Lozano etal., 2012).
In the context of our discussion another GBD 2010 report is even more interesting. Salomon and colleagues (2012) start their paper with the statement: ‘Improvement of population health means more than simply delaying death or increasing life expectancy at birth’. They continue: ‘With the trend of population ageing, the need to prioritize healthy ageing is increasingly recognized’. The authors of this paper focus on the description of ‘healthy life expectancy’ as a summary measure of population health. While this term has no philosophical or biological foundation, it is based on a lot of sound statistical reasoning. In fact, it goes back on a method developed 40 years ago by D. Sullivan. Healthy life expectancy is the number of years a person at a given age can expect to live in good health considering age-specific mortality, morbidity and functional health status. While health is here still largely defined negatively as the absence of disease, it becomes a measurable quantity and thus a simple logically appealing summary measure of population health. The GBD 2010 study goes even further by analyzing a composite metric that captures both premature mortality and the prevalence and severity of disease leading to the term of disability-adjusted life years (DALY) (Murray etal., 2012b). Health status was measured in other studies by the absence of disability expressed as activity restriction, or absence of dementia, or on a broader basis as a multidimensional expression of functioning. However, with a sufficiently large raw data set one can calculate the ‘healthy life expectancy’ in years. Then the difference between life expectancy minus healthy life expectancy can be interpreted as the average number of years of potentially healthy life lost to poor health. To get back to the above Bangladesh women who had in 2010 a life expectancy of 71 years, they had a healthy life expectancy of 59 years, for Canadian women the two figures were 83 and 68 years respectively. Despite different absolute numbers, women from both countries spent more than a decade with poor health. Interesting trends emerge: both for men and for women global healthy life expectancy has increased by about 4 years between 1990 and 2010 keeping with the overall trend of life expectancy increases. The gains in healthy life expectancy over the past 20 years have mainly been through reductions of child and adult mortality and not through reductions in years lost to disability (YLD). When looking into a study from member states of the European Union, larger variations were found for healthy life expectancy than for life expectancy (Jagger etal., 2008). These results are not just about statistics, they represent important elements for political decisions. The UN Millennium Development Goals have focused on the reduction of mortality from major killers like HIV, tuberculosis and malaria. With that focus life expectancy will (hopefully) increase, but it will have minor impact on healthy life expectancy. The computation of healthy life expectancy has changed over the years. Some used dichotomous weighting schemes categorizing people into either healthy or not. The new calculation accounts for the severity of disability calculated for 289 named diseases (Murray etal., 2012a) allowing thus a quantitative, gliding disability scale.
Ageing concepts
Every change or natural phenomenon such as aging is operated by underlying ‘Unchanging Principle’. For example, Chemical Compounds are operated by ‘Law of Definite Proportions’ or Proust’s Law of Definite Composition. Man, experiences aging changes while Chemical Elements and Chemical Compounds of his body remain unchanged.
The structure of the world population is dramatically changing with an increasing percentage of the human population living to old and very old age (Suzman and Haage, 2011). This phenomenon is not limited to the classical industrialized countries, until 2050 China is expected to reach 440 and 101 million inhabitants older than 60 and 80 years respectively (Shetty, 2012). This change in the population pyramid has not only important socioeconomic consequences (healthcare, pension funds), but affects also the health and disease discussion in an interesting way.
Like for health, everybody knows what ageing means, but definitions are again less obvious, and biologists have not yet developed a generally shared theory of ageing (Martin, 2011). Part of the problem might be that different organisms might have their own modes of ageing. Languages are not of much help: ‘age’ is something which can be very simply counted on a timescale. Different languages reflect a different attitude towards ageing: while in English ‘ageing’ implies deterioration, in Japanese it means just the advancement of age. A Japanese researcher has therefore defined ageing as a ‘regression of physiological function accompanied by advancement of age’ (Imahori, 1992). Medical doctors consequently differentiate a chronological and a physiological age of a person.
Medical gerontologists perceive ageing as a progressive decline in structure and function of the body (Ferruci and Studenski, 2011). Most prominent and very visible are the effects of ageing on body composition: lean body mass from muscles and visceral organs decrease steadily, muscle strength decreases (sarcopenia) and is a good predictor of mortality. Progressive demineralization leads to decline of bone strength that together with neurodegeneration induces unstable gait, poor balance and slow reaction times leading to falls and fractures resulting in increasing frailty. Memory decline and dementia are other neurological observations in some, but not all ageing persons. Decline of the sensory system is frequent (vision, hearing, taste). Another physiological change is declining resting metabolic rate with ageing, which is also a marker of illness. Homeostasis pathways (hormones, inflammatory mediators, antioxidants) change progressively with age inducing a lower resistance to stress. Normal ageing is also associated with a decline in food intake particularly in men which leads to malnutrition.
While ageing leads ultimately to death, great biological differences exist for lifespan and ageing process between different organisms. While the lifetime of fly’s measures in days, some ticks survive for decades and lobsters were reported to survive for more than 100 years without any apparent loss in fertility. Similar data have been reported for turtles, where older females lay more eggs than younger females, show no loss of vigor and no increase in mortality rate with increasing age (Finch, 2009). These observations led to the concept of negligible senescence and the Centenarian Species Project (Guerin, 2004). Negligible senescence contradicts Hamilton’s influential theory that natural selection shaped senescence (Hamilton, 1966) and ideas that late survival was sacrificed in evolution for reproduction (Kirkwood and Rose, 1991). Even today, Hamilton’s Forces of Natural Selection described in his 1966 paper were compared by evolution researchers to what is the Lorentz transformation for relativistic physics (Rose etal., 2007). Of course, working with long-lived animals which might have lifetimes longer than that of the researcher is not to the taste of geneticists who prefer short-lived animals like flies and worms or mostly mice where results are obtained within a grant period. However, negligible senescence would fit other theories, for example that of the French zoologist Buffon who suggested in the 18th century that the duration of life in animals corresponded to six to seven times that of the period of growth for the given animal. An animal which has undetermined growth like some reptiles (crocodiles for example grow as long as they live) could have a very long lifespan. Those zoologists might in fact be right who claim that lobsters die from predation, accident and infection but not as a consequence of ageing.
Many ideas have been developed by biologists on ageing: for example, Hayflick developed 40 years ago an argument that the finite number of cell doublings determines the lifespan of a species (Hayflick, 1968). Molecular biologists have added arguments to this idea by highlighting the importance of telomere length shortening with increasing cell divisions. Several other mechanisms and pathways have been revealed by molecular biologists and geneticists for the ageing process. Caloric restriction and longevity is another of the fruitful fields of ageing research. Whether it applies to monkeys as our closest relatives is currently the focus of much discussion (Mattison etal., 2012).
However, all what we have discussed so far fit more the fundamental interest of biologists than that of the medical doctor. For the present review let’s therefore focus on the human condition and the medical view on healthy ageing.
Healthy ageing
Man’s experience of time and its consequence called aging is operated by sensory experiences that are fundamentally false. Man’s existence demands influence of grand illusion that protects man from experiencing speed of planet Earth.
Thirty years ago, Fries (1980) published in The New England Journal of Medicine a seminal paper on ‘Ageing, natural death, and the compression of morbidity’ which heavily influenced the medical discussion on ageing. He starts with the statement that the length of life is fixed; speculations on immortality are rooted in human hope. The medical field assumes that death is always the result of a disease process, but due to his hypothesis of a set human lifespan, death might occur without overt disease when the normal span is lived. In his paper he depicted the ‘ideal’ human mortality curve in the absence of premature death: it is a sharp peak around the ‘naturally set’ human lifespan of 85 years. He arrived at this value from the extrapolation of life expectancy data at birth and at age 20 and 65 measured over the last century which intersect in his graph at 85 years. With that idealized model the survival curve of humans has a sharp rectangular form while the actual survival curve for humans at 1900 looked more like a triangle with a continuous decline of survival with age. In 1980 the survival curve took already a substantial rectangular form: much of the 1900-typical attrition over increasing age had been eliminated and the actual survival curve started to approach the ideal curve. He admitted that the average length of life was increasing, but he argues that this was due to a decrease in childhood mortality, not to a secular trend for an increase of life expectancy at age of 75 years. He highlighted that acute, usually infectious diseases determined mortality in the USA at 1900 and that chronic diseases have now superseded acute diseases. In his view health improvement must address chronic instead of acute diseases, morbidity and not mortality, quality of life rather than duration of life. Postponement of disease is more important than cure of a disease. Weight control, regular exercise, treatment of hypertension, elimination of smoking and alcohol over-consumption (today we would add an equilibrated diet) were the practical measures. With that focus of medical interventions, one could achieve what he called the compression of morbidity. A postponement of chronic disease would also result in a rectangularization of the morbidity and not only the mortality curve. Since loss of reserve function represented his operational definition of ageing, one could theoretically also achieve a compression of senescence. He postulated a plasticity of ageing against a non-elasticity of the human ideal lifespan.
It is interesting to compare the Fries’ model with the actual data set from the GBD 2010 study. Already in an analysis of demographic data from 2002, the WHO reported that precisely the very old age groups are growing the fastest worldwide. A cornerstone of Fries’ model is the lack in increase of centenarians over one century of observation. The WHO projects in contrast a 13-fold increase in centenarians over the next decades (Kalache etal., 2002). Better hygiene, nutrition and healthcare have increased life expectancy as also seen in GBD 2010. When the life expectancy of females in the most advanced nations is plotted against historical time, a straight line is observed showing a steady increase of 2.5 years longer life expectancy per decade between 1850 and 2000 (Suzman and Haage, 2011). Humans in some industrialized countries have now nearly reached the lifespan limits of Buffon’s formula, but the asymptotic behavior requested by a genetically fixed life expectancy was not yet observed. One central tenet of the Fries’ model is thus not confirmed. What about the compression of morbidity? GBD 2010 showed that countries with high life expectancy had mostly also lower age-specific disability than countries with low life expectancy. While an analysis of disability-adjusted life expectancy (DALE) with data from the GBD 1999 study (Mathers etal., 2001) showed still ‘some evidence to suggest that compression of morbidity may be occurring in some low mortality countries’, later analyses did not concur with this interpretation. According to GBD 2010, years lived with disability (YLD) rose despite a decrease in the prevalence of age-specific disability (Salomon etal., 2012). Simply, the decrease in disability did not keep pace with the increase in survival. A compression can only occur if healthy life expectancy would rise faster than life expectancy.
Globally, YLD rose from 583 million in 1990 to 777 million in 2010 (Vos etal., 2012). The main contributors at the global level were mental and behavioral disorders, musculoskeletal disorders, diabetes and endocrine diseases. The leading specific causes were the same in 2010 as in 1990: low back pain, major depressive disorders, iron-deficiency anemia, neck pain, chronic obstructive pulmonary disease, anxiety disorders, migraine, diabetes and falls. Rates of YLD per given number of people did not change, but since YLD rise steadily with age, population growth and ageing were the major drivers for the increase in YLD (Vos etal., 2012). The health system is thus confronted with a rising number of individuals with a range of disorders that largely cause disability but not mortality.
Outlook
John Milton in his epic poem of Paradise Lost, Book XI shared the golden principles of healthy aging. Nothing too much, the Law of Temperance helps man to live to his fullest potential.
I yield it just, said Adam, and submit. But is there yet no other way, besides These painful passages, how we may come To Death, and mix with our connatural dust?
There is, said Michael, if thou well observe [ 530 ] The rule of not too much, by temperance taught In what thou eat and drink, seeking from thence Due nourishment, not gluttonous delight, Till many years over thy head return: So may thou live, till like ripe Fruit thou drop [ 535 ] Into thy Mothers lap, or be with ease Gathered, not harshly plucked, for death mature:
In summary, GBD 2010 showed clear evidence of expansion, not compression of morbidity. An increase of the number of years lived in reduced health has implications beyond the person suffering from restricted health. Healthy ageing is a socioeconomic need since otherwise national health systems will not be able to stem the cost associated with managing increasing numbers of individuals suffering from various disease sequelae. If by preventive measures a healthy ageing could be achieved, the healthcare system could save cost and the individual could enjoy a greater quality of life for a longer period of life. This goal is quite ambitious though, but the incentive is great justifying the exploration of various associations with healthy ageing. In an accompanying review, I explore the data associating gut microbiota composition with healthy ageing and to what extent the gut microbiota composition can be changed by nutritional interventions (Brüssow, 2013).
Acknowledgments
I thank my colleagues Wolfram Brück for critical reading of the manuscript and Olga Sakwinska for stimulating discussions.
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Whole Foods-Whole Inspiration-Whole LanguageWhole Foods Arrives in Ann Arbor, September 1993Whole Foods opened its Store in Ann Arbor on September 16, 1993. Whole Foods, Whole People and Whole Planet inspire Whole Dude to invent Whole Phrases: Whole Linguistics – Whole Language. The concept of Whole Cookie and Whole Love. Whole Dude uses the phrase Whole Linguistics to describe three entities; 1. Language User, 2. Language Interpreter and 3. Language Creator. Image Credit: Agenda Publications, Ann Arbor District Library, Issue Dates, September 1993, December 1997 and February 1998.
Yes indeed, Life is complicated. Whole Dude cannot support his mortal existence on the basis of his physical and mental work. Whole Dude lives in Love, the Love that brings together Whole Foods, Whole People, and the Whole Planet, the Force that sets Life in Motion.
Physics of Spirituality Science – Love is a Fundamental Force
Whole Dude lives in Love, the Love that brings together Whole Foods, Whole People, and the Whole Planet, the Force that sets Life in Motion.
Physics of Spirituality Science – Love is a Fundamental Force. PHYSICS MAY NOT ACCOUNT FOR INTERACTIONS BETWEEN LIVING AND NONLIVING MATTER. PHYSICAL FORCES CANNOT ACCOUNT FOR TWO TYPES OF MOTION. THESE ARE, 1. OBSERVED VARIATIONS IN ROTATIONAL SPINS OF PLANETS, AND 2. MOTION OF LIVING MATTER.
In Physics, the term ‘Fundamental’ is used to describe a Principle, Theory, Law etc., serving as a basis forming a foundation that could be essential to explain other interactions in the natural world. In Physics, the term ‘Force’ is used to describe the cause or agent that puts an object at rest into motion or alters motion of a moving object.
Whole Dude lives in Love, the Love that brings together Whole Foods, Whole People, and the Whole Planet, the Force that sets Life in Motion.
Physics of Spirituality Science – Love is a Fundamental Force. Physics accounts for Four Fundamental Interactions. In Natural World, there are Interactions between Living and nonliving Matter which are fundamentally different from Interactions explained by Physics. All known physical interactions of Matter occur through the agency of four basic, or ‘Fundamental’ kinds of ‘Forces’; 1. Strong Nuclear Force, 2. Weak Nuclear Force, 3. Electromagnetic Force, and 4. Gravitation Force. Most natural phenomena can be accounted for in terms of Four Fundamental Interactions. Gravitation and Electromagnetism act over long distances and it is easy to observe their effects. Strong and Weak Nuclear Forces act over subatomic distances and the range of their effects is limited.
Whole Dude lives in Love, the Love that brings together Whole Foods, Whole People, and the Whole Planet, the Force that sets Life in Motion.
Physics of Spirituality Science – Love is a Fundamental Force: LOVE IS A FORCE THAT CANNOT BE MEASURED BY INSTRUMENTS INVENTED BY PHYSICISTS. Gravitation is the pervasive Fundamental Interaction. Every particle of Matter seems to attract every other particle with a Force that is proportional to the Mass of each and inversely proportional to the square of their separation. This relationship was first proposed by Sir Isaac Newton. His Theory of Gravitation is ‘Fundamental’, in the sense that all Motion due to the gravitational forces exerted on all objects can be described as a result of the same Force. Gravitation causes apples to fall from trees and determines the orbits of planets around Sun.
Whole Dude lives in Love, the Love that brings together Whole Foods, Whole People, and the Whole Planet, the Force that sets Life in Motion.
Physics of Spirituality Science – Love is a Fundamental Force: FUNDAMENTAL PHYSICAL FORCES CANNOT ACCOUNT FOR VARYING ROTATIONAL SPINS OF ASTRONOMICAL BODIES.
Each planet of our Solar System exists as a unique, original, one of its own kind of object.
Mechanics is the branch of Physics that deals with motion of material bodies and the phenomena of action of forces on bodies. Celestial Mechanics is the study of motion of astronomical bodies as they move under the influence of their mutual gravitation. If the forces acting on a System do not cancel, Motion will result. Calculation of such motions is complicated because many separate forces are acting at once and all bodies are moving simultaneously. Isaac Newton’s Laws of Motion and Theory of Universal Gravitation provide a great understanding of the simple elliptical orbits as described by Kepler’s Laws of Planetary Motion.
Whole Dude lives in Love, the Love that brings together Whole Foods, Whole People, and the Whole Planet, the Force that sets Life in Motion.
Physics of Spirituality Science – Love is a Fundamental Force: KEPLER’S LAWS MAY ACCOUNT FOR ORBITAL MOTIONS OF PLANETS. HOW ABOUT EXPLAINING ROTATIONAL SPINS OF PLANETS? It is interesting to note Hindu Scriptures called Vedas may describe or mention Earth’s rotational spin. Neither Vedas, nor Science have accounted for a ‘Force’ that initiated rotational spin of various celestial bodies. Rotational Spin is different from orbital motion displayed by planets. Rotational Spin of planets cannot be explained as caused by physical forces of mutual attraction between celestial objects. Newton maintained that mere Motion does not require application of Force. In Space, there is no friction to restrain motions of celestial bodies.
Whole Dude lives in Love, the Love that brings together Whole Foods, Whole People, and the Whole Planet, the Force that sets Life in Motion.
Physics of Spirituality Science – Love is a Fundamental Force: PHYSICAL FORCE SUCH AS GRAVITATION ACCOUNTS FOR EARTH’S ORBIT OR REVOLUTION AROUND SUN. THERE IS NO PHYSICAL FORCE TO ACCOUNT FOR EARTH’S ROTATION ON ITS AXIS.
The man’s existence on surface of Earth cannot be fully accounted by physical force of Gravitation that explains Earth’s orbit or revolution around Sun. Man travels about 67, 000 miles per hour during Earth’s yearly orbit around Sun. Man’s lifetime or lifespan on Earth is determined by alternating periods of Day and Night caused by Earth’s rotational spin. Physical Forces act mechanically without sense of purpose or goal. Earth’s rotational spin serves a specific purpose for it directs Biological Rhythms of Living Systems.
Whole Dude lives in Love, the Love that brings together Whole Foods, Whole People, and the Whole Planet, the Force that sets Life in Motion.
Physics of Spirituality Science – Love is a Fundamental Force: Physical Force may account for the Speed of a point on the surface of Earth. Living Systems have synchronized their Biological Rhythms with Rotational Spin of Earth which serves specific purpose by causing alternate periods of Light and Darkness called Day and Night.
Whole Dude lives in Love, the Love that brings together Whole Foods, Whole People, and the Whole Planet, the Force that sets Life in Motion.
Physics of Spirituality Science – Love is a Fundamental Force: Man travels nearly 67,000 miles per hour in yearly orbit around the Sun. Earth’s Orbital Motion does not determine Man’s lifetime or lifespan. Man’s lifetime is measured by alternating periods of Day and Night caused by Earth’s rotational spin. Within our Solar System, no celestial object shares rotational spin characteristics of another object. Each planet spins at a different speed or exhibits different rotational axis. On each planet, we will experience Day and Night and Seasons in different manners as they orbit around Sun. Each planet is unique, distinctive, original, and one of its own kind of celestial object. Space Exploration discovered thousands of planets, but none of them share identical rotational spins, in fact each planet displays individualistic variation in its spin characteristics. So, we need to recognize existence of an”UNKNOWN” Force that may have imparted energy to initiate rotational spin of each celestial object.
Whole Dude lives in Love, the Love that brings together Whole Foods, Whole People, and the Whole Planet, the Force that sets Life in Motion.
Physics of Spirituality Science – Love is a Fundamental Force: TILT AND ROTATION AXIS OF PLANETS SHOW INDIVIDUALISTIC VARIATIONS. EARTH’S TILT AND ROTATION AXIS ARE PURPOSIVE AND GOAL-ORIENTED AS IT DRIVES BIOLOGICAL RHYTHMS.
Whole Dude lives in Love, the Love that brings together Whole Foods, Whole People, and the Whole Planet, the Force that sets Life in Motion.
I am using the term ‘LOVE’ to define it as a Fundamental Force that brings Unity and Harmony in Interactions between Inanimate and Animate Matter to establish Natural Order. LOVE is Fundamental to existence of Sensible or Living Matter. Living Things have the ability to perceive LOVE which instruments developed by man cannot measure.
Rudolf Virchow is reborn as Whole Dude to describe the spiritual connection between the Cell and its Energy Provider
Whole Dude lives in Love, the Love that brings together Whole Foods, Whole People, and the Whole Planet, the Force that sets Life in Motion.
Whole Dude acknowledges his German heritage at Whole Foods when he discovered the spiritual connection between man, food, and Providence. Whole Foods, Whole People, and Whole Planet are connected by a material substance called Protoplasm or Cytoplasm, a divine plan to provide nourishment to Life.
Whole Dude lives in Love, the Love that brings together Whole Foods, Whole People, and the Whole Planet, the Force that sets Life in Motion.
The Rudolf Virchow Connection at Whole Foods, Ann Arbor can be best described as the concept of Whole Spirituality, the three dimensional spiritual relationship between the multicellular human organism, food, and the Divine Providence.
The Rudolf Virchow Connection at Whole Foods, Ann Arbor can be best described as the concept of Whole Spirituality, the three dimensional spiritual relationship between the multicellular human organism, food, and the Divine Providence.
Spiritualism – The Cell Theory of Spirituality
The Rudolf Virchow Connection at Whole Foods, Ann Arbor can be best described as the concept of Whole Spirituality, the three dimensional spiritual relationship between the multicellular human organism, food, and the Divine Providence.
In Biology, cell is the basic or fundamental unit of structure, function, and organization in all living things or it is the building block of life. Let me begin with my respectful tribute to some of the people who contributed to ‘The Cell Theory’, one of the foundations of Biological Sciences. Cells were first observed in the 17th century shortly after the discovery of the microscope. Robert Hooke, british curator of instruments at The Royal Society of London, during 1665 coined the word cell. Dutch microscopist Antonie Van Leeuwenhoek (1632-1723) made over 247 microscopes and examined microorganisms and tissue samples. He gave the first complete descriptions of bacteria, protozoa (which he called animalcules), spermatozoa, and striped muscle. He also studied capillary circulation and observed Red Blood Cells.
Robert Hooke, british curator of instruments at The Royal Society of London coined the term cell during 1665.Dutch microscopist Antonie Van Leeuwenhoek (1668-80) studied capillary circulation and observed Red Blood Cells.
Improvements in microscopy during early 19th century permitted closer observation and the significance of cells had received better understanding. Matthias Jakob Schleiden (1838), german botanist, Theodor Schwann (1839), german physiologist, and Rudolf Virchow (1855), german pathologist, and others made important contributions to the Cell Theory that describes cell as the building block of all Life.
Schleiden, Professor of Botany, The University of Jena studied plant structure under the microscope, published “Contibutions to Phytogenesis”(1838). He had also published the two-volume text of ‘Principles of Scientific Botany’.Schwann founder of modern Histology extended the Cell Theory of Plants to animals in his ‘Microscopic Researches into Accordance in the Structure and Growth of Animals and Plants(1839).Schwann discovered Myelin Sheath covering peripheral axons, now termed Schwann Cells. He coined the term ‘Metabolism’ for the chemical changes that take place in living tissues.Rudolf Virchow,german pathologist in 1855 coined the biological dictum “OMNIS CELLULA E CELLULA” – All living cells arise only from pre-existing living cells.
The Cell is the smallest unit in the living organism that is capable of carrying on the essential life processes of sustaining metabolism for producing energy and reproducing. Many simple, small, single-celled organisms like Protozoa perform all life functions. In higher, complex, bigger, multicellular organisms, groups of cells are structurally and functionally differentiated into specialized tissues and organ systems. Thus, the Cell Theory includes the following foundational principles of the Biological Sciences:
1. All living things are made up of cells. Cell is the most elementary or basic unit of Life.
2. Cell is a fundamental unit of structure, function, and organization in all living things including plants and animals.
3. Cells only rise from division of previously existing cells.
4. All cells are similar in composition, form, and function. All cells are basically the same in chemical composition (in spite of variations) in organisms of similar species. For example, all the solid tissues in the human body can be shown to consist largely of similar cells; differing it is true, but that are essentially similar to an Ovum.
5. The cells exhibit functional autonomy. The activity of an organism depends on the total activity of ‘INDEPENDENT’ cells.
6. Energy flow (metabolism and biochemistry) occurs within cells.
7. Cells contain hereditary, biological information (DNA) which is passed from cell to cell during cell division.
The Cell Theory of Spirituality
The Rudolf Virchow Connection at Whole Foods, Ann Arbor can be best described as the concept of Whole Spirituality, the three dimensional spiritual relationship between the multicellular human organism, food, and the Divine Providence.
The basic or fundamental unit of life in the human organism is derived from the fertilized egg cell that eventually develops into a complete organism. The most significant feature of similarity between the cells of the human body is the presence of a soft, gelatinous, semi-fluid, granular material inside the cell. This substance known as Protoplasm or Cytoplasm, or Cytosol is similar to the ground substance found in the Ovum or the Egg Cell.
Human Ovum Structure – The Cell Theory of Spirituality is based upon the Substance, Structure, Form, Organization, Function, Action and Interactions of this Single Fertilized Egg Cell that eventually develops into a complete human organism.
This viscous, translucent, colloidal substance is enclosed in a membrane called Cell Membrane, Plasma Membrane or Biological Membrane. A small spherical body called nucleus is embedded in the Protoplasm of the cell. The three essential features of any living cell in the human body are that of the presence of protoplasm, the nucleus, and the cell membrane.
Protoplasm – The Ground Substance of Spiritualism and Spirituality
In the middle of the 19th century, various biologist started to recognize the importance of Juicy or Slimy contents of the cells. Purkinje (1839) gave the name protoplasm (Gr., Protos- primitive or first, plasma- substance) to the contents of the cells. This theory states that the cell is an accumulation of living substance or protoplasm, definitely limited in space and possessing a nucleus and a cell membrane .
I seek the existence of Soul or Spirit in a substance that is basic to life activities, and in a material that is responsible for all living processes. I, therefore, propose that the understanding of the true or real nature of this ground substance of all living matter will help man to discover peace, harmony, and tranquility in all of his internal and external relationships while man exists in a physical environment as a member of a social group, social community, and Society. In this blog post, I would like to pay my respectful tribute to Jan Evangelista Purkinje and Hugo Von Mohl for their great contribution to the scientific understanding of the living substance, living material, and living matter.
Jan Evangelista Purkyne(Czech name), Jan Evangelista Purkinje(German name)also known as Johannes Evangelist Purkinje, b. December 17, 1787, d. July 28, 1869. The pioneer Czech experimental Physiologist whose investigations in the fields of Histology, Embryology,and Pharmacology helped create a modern understanding of the eye and vision, brain and heart function, mammalian reproduction, and the composition of cells.
Purkinje conducted his research on human vision at the University of Prague and later on, he served there as a Professor of Physiology (1850-69). He went to Germany and was appointed the Chair of Physiology and Pathology (1823-50) at the University of Breslau, Prussia. There Purkinje created the world’s first independent Department of Physiology (1839) and the first Physiological Laboratory (Physiological Institute, 1842). He is best known for his discovery of large nerve cells with many branching extensions found in the cortex of Cerebellum of the brain (Purkinje Cells, 1837). He discovered the fibrous tissue that conducts electrical impulses from the ‘pacemaker’ called Atrioventricular node or A-V node along the inside walls of the ventricles to all parts of the heart to help in Cardiac contractile function (Purkinje Fibers, 1839). In 1835, he invented and introduced the scientific term ‘Protoplasm’ to describe the ground substance found inside young animal embryo cells. He discovered the sweat glands of the skin (1833); he discovered the nine configuration groups of Fingerprints used in biometric identification of man (1823); he described the germinal vesicle or nucleus of the unripe ovum that now bears his name (1825), and he noted the protein digesting power of pancreatic extracts (1836).
Hugo Von Mohl, b. April 08, 1805, d. April 01, 1872, German Botanist noted for his research on the anatomy and physiology of plant cells.
Hugo Von Mohl named the granular, colloidal material that made up the main substance of the plant cell as “Protoplasm” in 1846. Purkinje invented the word, but Hugo gave more clarity, understanding, and knowing the nature of this ground substance. He viewed cell as an “elementary organ” and in Physiology he explained Protoplasm as an organ of Motion or Movement, Nutrition, and Reproduction. It is the preliminary material in cellular generation. He was the first to propose that new cells are formed by division of preexisting cells and he had observed this process of Cell Division in the algal cells of Conferva glomerata. His observations are very important to understand the Cell Theory that explains cells as the basic building blocks of Life. He was the first to investigate the phenomenon of the stomatal openings in leaves.
The Ground Substance of Spiritualism and Spirituality. The vital characteristics, the animating principles of Protoplasm could be known by observing Amoeba proteus. The Living Substance works as an organ of Motion or Movement, as an organ of Nutrition, and as an organ of Reproduction to generate new cells which have a life span of their own. In these physiological functions, I describe the characteristics such as Cognition, Consciousness, Memory, and Intelligence which have a Spiritual role as they bring functional unity and harmony in the interactions between different parts of the same individual organism while it exists in an environment as a member of a biological community.
Protoplasm is a complex, viscous, translucent solution of such materials as salts and simple sugars with other molecules, mostly proteins and fats, in a colloidal state, that is dispersed but not dissolved in one another. Carbon, Hydrogen, Oxygen, and Nitrogen constitute more than 90 percent of Protoplasm.
Whole Foods, Whole People, and Whole Planet are connected by a material substance called Protoplasm or Cytoplasm, a divine plan to provide nourishment to Life.Whole Foods, Whole People, and Whole Planet are connected by a material substance called Protoplasm or Cytoplasm, a divine plan to provide nourishment to Life.
It exhibits properties such as Protoplasmic Streaming or Cytoplasmic Streaming or Motion that is called “Amoeboid Movement.” It has the intrinsic power to change its shape and position. It has the power of Nutrition by which it can attract and obtain the materials necessary for its growth and maintenance from surrounding matter/environment.
Whole Foods, Whole People, and Whole Planet are connected by a material substance called Protoplasm or Cytoplasm, a divine plan to provide nourishment to Life.
The living functions such as Nutrition, Cellular Respiration, and Reproduction performed by Cytoplasm involve acquiring, processing, retaining, and using information to perform tasks in a sequential manner for a predetermined purpose and hence describe Consciousness, Memory, and Intelligence.
The Rudolf Virchow Connection at Whole Foods. God created Cytoplasm or Protoplasm as the Ground Substance of Spirituality. Cellular respiration is a set of metabolic reactions and processes that take place in the cells of organisms to convert biochemical energy from nutrients into adenosine triphosphate (ATP), and then release waste products.Whole Foods, Whole People, and Whole Planet are connected by a material substance called Protoplasm or Cytoplasm, a divine plan to provide nourishment to Life.Whole Foods, Whole People, and Whole Planet are connected by a material substance called Protoplasm or Cytoplasm, a divine plan to provide nourishment to Life.Whole Foods, Whole People, and Whole Planet are connected by a material substance called Protoplasm or Cytoplasm, a divine plan to provide nourishment to Life.
The terms Soul and Spirit belong to the materialistic realm where the Physical Reality of man’s biological existence is established. I have not yet discovered any good reason to use the terms Soul and Spirit as a metaphysical or transcendental Reality.
The Inheritance of Cytoplasmic Membrane or Cell or Plasma Membrane:
The Rudolf-Rudi Connection at Whole Foods. God created Cytoplasm or Protoplasm as the Ground Substance of Spirituality. Living cells have a corporeal substance called Protoplasm that has the ability of Spiritual Biotic Interactions. The Biological Membrane or Cell Membrane separates the cell from its environment and other living cells present in the environment. Cells use unique proteins, biological molecules and receptor sites to recognize the other living cells and use chemical signals to facilitate the interactions. Such interactions between living cells have the characteristics of consciousness or awareness.The Rudolf Virchow Connection at Whole Foods. God created Cytoplasm or Protoplasm as the Ground Substance of Spirituality. Cytoplasmic Membrane or Cell Membrane is an integral feature of Cytoplasm, a limiting membrane devised by Cytoplasm to create boundaries to perform its numerous living functions.
The Functions of Cytoplasmic Membrane or Cell Membrane or Biological Membrane:
1. Protection: It protects the cell from its surroundings or extracellular environment. Plant cell possess wall over the plasma membrane for extra protection and support.
2. Holding cell contents: Plasma membranes hold the semi fluid protoplasmic contents of the cell intact; thus keeping the individuality of the cell.
3. Selective Permeability: Cell membrane allows only selected or specific substances to enter into the cell and are impermeable to others.
Gases like O2 and CO2 can diffuse rapidly in solution through membranes.
Small compounds like H2O and methane can easily pass through where as sugars, amino acids and charged ions are transported with the help of transport proteins.
The size of the molecules which can pass through the plasma membrane is 1-15 A0. This property is responsible for keeping a cell ‘as a cell’, an individual unit.
4. Shape: It maintains form and shape of the cell. It serves as site of anchorage or attachment of the cytoskeleton; thus providing shape to the cell (especially in animal cells without cell wall).
5. Organelles: Cell membrane delimits or covers all sub-cellular structures or organelles like nucleus, mitochondria, plastids, Golgi apparatus, endoplasmic reticulum, microbodies etc. thus protecting them form the surroundings and also helps in maintaining a constant internal environment.
6. Compartmentalization: Cell membrane separate the cells from their external environment and cell organelle from cytosol. It help the cells and their organelles to have their own microenvironments, structural and functional individuality.
7. Cell Recognition: With the help of glycolipids and glycoproteins on its surface, cell membranes are able to differentiate similar cells from dissimilar ones, foreign substances and cells own materials. Cell recognition is useful for tissue formation and defence against microbes.
8. Antigens: Cell membranes possess antigens which determine blood grouping, immune response, acceptance or rejection of a transplant (graft rejection by MHC’s on plasma membrane).
9. Microvilli: They are microscopic finger like projections of plasma membrane present on some cells like intestinal epithelial cells, which are involved in a wide variety of functions, including increasing surface area for absorption, secretion, cellular adhesion etc.
10. Sheaths of cilia and flagella: Cilia and flagella are projections from the cell; made up of microtubules which are covered by an extension of the plasma membrane.
11. Cytoplasmic bridges in plasmodesmata and gap junctions: Plasmodesmata in plant cells and gap junctions in animal cells; meant for intercellular transport and communication, form cytoplasmic bridges between adjacent cells through plasma membrane.
12. Endocytosis and Exocytosis: Bulk intake of materials or endocytosis occurs through development of membrane vesicles or invagination and engulfing by plasma membrane.
Exocytosis: It is reverse of endocytosis that provides for releasing waste products and secretory materials ot of the cells with the help of plasma membrane.
13. Impulse transmission in neurons: The transmission of a nerve impulse along a neuron from one end to the other occurs as a result of electrical changes across the plasma membrane of the neuron
14. Cell metabolism: Cell membranes control cell metabolism through selective permeability and retentivity of substances in a cell.
15. Electron transport chain in bacteria: In bacteria; Electron transport chain is located in cell membrane.
16. Osmosis through cell membrane: It is movement of solvent molecules (generally water) from the region of less concentrated solution to the region of high concentrated solution through a semi permeable membrane. Here the semi permeable membrane that helps in osmosis is the cell membrane. Eg: Root cells take up water from the soil by osmosis
17. Carrier proteins for active transport: They occur in the cell membranes and control active transport of substances. Example, GLUT1 is a named carrier protein found in almost all animal cell membranes that transports glucose across the bilayer or plasma membrane.
18. Plasma Membrane enzymes: Many enzymes are present on the plasma membrane with wide variety of catalytic activity. Example: Red blood cell plasma membranes contain a number of enzymes such as ATPases, anion transport protein, glyceraldehyde 3-phosphate dehydrogenase, protein kinases, adenylate cyclase, acetylcholinesterase.
19. Cell Membrane Receptors: Receptor on the plasma membrane performs signal transduction, converting an extracellular signal into an intra-cellular signal. Membrane possess receptors for hormones, neurotransmitters, antibodies and several other biochemicals.
20. Plasma membrane assisted Cell movements: Undulation and pseudopodia are cell membrane phenomenon involved in cell movement. Amoeba, macrophages and WBCs move with the helps of temporary organelles like pseudopodia. Pseudopods are temporary cytoplasmic projections of the cell membrane in certain unicellular protists such as Amoeba. Some mammalian cells such as fibroblasts can move over a solid surface by wave like undulations of the plasma membrane.
The Ground Substance of Spiritualism and Spirituality. The vital characteristics, the animating principles of Protoplasm could be known by observing Amoeba proteus. The Living Substance works as an organ of Motion or Movement, as an organ of Nutrition, and as an organ of Reproduction to generate new cells which have a life span of their own. In these physiological functions, I describe the characteristics such as Cognition, Consciousness, Memory, and Intelligence as spiritual attributes of Life as they bring functional unity and harmony in the interactions between different parts of the same individual organism while it exists in an environment as a member of a biological community.
The Spirituality of Substance, Function, Organization, Action and Interactions:
Whole Foods, Whole People, and Whole Planet are connected by a material substance called Protoplasm or Cytoplasm, a divine plan to provide nourishment to Life.
To establish the biological existence of the human organism, I add the concept of Spiritualism and Spirituality to the Cell Theory.
Whole Foods, Whole People, and Whole Planet are connected by a material substance called Protoplasm or Cytoplasm, a divine plan to provide nourishment to Life.
The Single Fertilized Egg Cell has ground substance that is of Spiritual nature and the Spiritualism and Spirituality consists of the following functional, and organizational characteristics:
1. The Cell is Conscious of its own existence and knows its internal condition and knows it external environment.
2. The Cell is intelligent and it has the cognitive abilities like perception and memory to acquire information, to retain information, to recall information, and to use information in the performance of its complex tasks in a sequential manner.
3. The Cell has the ability to show characteristics such as mutual cooperation, mutual tolerance, and display functional subordination and subservience while being independent.
4. The Cell grows, divides, and develops into a complete organism while it acquires substances and energy from an external environment. The power of Protoplasm/Cytoplasm to attract matter found in its external environment is called Nutrition. The Cell continuously transforms matter to build matter of its own kind for its own benefit to sustain its existence with its own identity and individuality. The Organism represents a social group or a biological community of Cells. The Spiritual nature of Protoplasm/Cytoplasm brings this functional harmony and unity in the Social Group or Biotic Community of Cells by bringing together its Essence and Existence.
5. The Cell Theory is incomplete for it does not describe the conditioned nature of the Cell’s existence. The Cell represents a Living System that is thermodynamically unstable. It requires a constant supply of matter and energy from its external environment to sustain its living functions. The concept of Whole Spirituality formulates the connection between the Cell and its external source of matter and energy.
The Rudolf Virchow Connection, The Discovery of Whole Spirituality at Whole Foods, Ann Arbor. The Bone Marrow smear from a patient of Leukemia or Blood Cancer helps to illustrate the nature of Biotic Interactions in the Social Group or Biotic Community that represents the singularity called man. The true or real man can only be discovered by the microscopic study of the Cells that constitute the Organism.
The theoretical claims about Spirit and Soul, the religious and philosophical doctrines of Spiritualism and Spirituality must be verified using the Cell Theory that defines the human organism. To describe Soul or Spirit as nonmaterial or immaterial Self will not help man to know the real or true man.
The theoretical claims about Spirit and Soul, the religious and philosophical doctrines of Spiritualism and Spirituality must be verified using the Cell Theory that defines the human organism. To describe Soul or Spirit as nonmaterial or immaterial Self will not help man to know the real or true man.
Whole Foods Arrives in Ann Arbor, September 1993. The Rudolf Virchow Connection at Whole Foods, Ann Arbor can be best described as the concept of Whole Spirituality, the three dimensional spiritual relationship between the multicellular human organism, food, and the Divine Providence.
Whole Foods, Whole People, and Whole Planet come together in a Wholesome Relationship as God is the Energy Provider, the Original Source of Matter and Energy for Life.
Whole Foods, Whole People, and Whole Planet come together in a Wholesome Relationship as God is the Energy Provider, the Original Source of Matter and Energy for Life.
SPIRITUALISM AND VIOLENCE – GRIEF AT SANDY HOOK ELEMENTARY SCHOOL:
Spiritualism: Grief and Compassion at Sandy Hook Elementary School, Newtown, Connecticut, Friday, December 14, 2012.
In U.S. history, the second-deadliest school shooting took place at Sandy Hook Elementary School, Newtown, Connecticut during the beautiful morning hours on Friday, December 14, 2012. The killing of 20 school children and other adults will force us to reflect upon human nature.
The tragedy at Sandy Hook: 6-year-old Emilie Parker is one of the shooting victims. She is seen in this photo with her father Robbie Parker.
This act of violence at Sandy Hook compels us to examine the Spiritual Basis for human existence.
AGGRESSION AND HUMAN RELATIONSHIPS:
Among animals, man has the ability to kill members of his own kind for reasons other than that of food, territory, and reproductive success. However, I do not consider that aggression is innate to human nature. The thought to commit an act of violence may enter the human mind because of an external, environmental stimulus. For an infectious agent to enter human body and cause a diseased condition would require a degree of susceptibility to that infection. A person who is not in proper relationship with his own self, and with others is susceptible to be taken over by harmful emotions such as anger that generates the desire to commit an act of violence. The gunman at Sandy Hook Elementary School could be described as a victim of his inability to formulate harmonious relationship both at personal level and interpersonal level. Mental Health involves the ability to develop harmonious social relations. In my view, the basis for external, harmonious, social relationships begins at a personal level; the ability to define one’s relationship with oneself.
THE SPIRITUAL BASIS FOR HUMAN EXISTENCE:
This act of violence at Sandy Hook Elementary School illustrates man’s estrangement or alienation from his true or real nature. I would like to reinforce the fact of the spiritual basis for human existence. In life, or death, man needs the mercy, grace, and compassion of his Creator. Man does not exist in this physical world because of his intellectual, or physical effort. It is a good time to explain the dependent nature of human existence and invite peace, harmony, and tranquility in the living condition by accepting the Divine Providence with a sense of respect and humility. The act of acceptance of Divine mercy, grace, and compassion generates the emotion called ‘devotion’ which provides a sense of comfort and makes the person stress-resistant, and imparts the ability to overcome the feelings of fear, and the sense of grief generated by the loss of life.
GRIEF AND COMPASSION AT SANDY HOOK ELEMENTARY SCHOOL:
SPIRITUALISM AND VIOLENCE: GRIEF AND COMPASSION AT SANDY HOOK ELEMENTARY SCHOOL.
It is human nature to respond to grief with feelings of compassion. I describe, that human nature is constituted by the principles called ‘spirit’, and ‘soul’. In ‘spirit’, man seeks freedom, and with ‘soul’, he establishes the dependence that supports the human existence. The violence, and aggression that we have witnessed is a response to an external environmental stimulus. Man betrays his own true nature or fails to recognize his real self; and this sense of estrangement or alienation from reality leads to behavior that destroys peace, harmony, and tranquility in man’s interactions with others in his environment. This gunman at Sandy Hook Elementary School had utterly failed to defend his own freedom as he got alienated from his own ‘spirit’ and had failed to recognize his own ‘soul’ that sustains his existence. This loss of freedom had caused him to end his own existence using the same gun with which he had attacked others.
SPIRITUALISM – TIME AND LIFE – SPIRITUAL INTERACTIONS :
LORD GAUTAMA BUDDHA HAD OBSERVED THAT WHATEVER IS BORN, PRODUCED, OR CONDITIONED CONTAINS WITHIN ITSELF THE NATURE OF ITS OWN DISSOLUTION. LIFE IS CONDITIONED TO EXPERIENCE CHANGE UNDER THE INFLUENCE OF TIME AND LIVING THINGS ARE BORN TO EXPERIENCE DISSOLUTION AT THE END OF THEIR LIFETIME.
Gautama Buddha had observed that whatever is born, produced, conditioned, contains within itself the nature of its own dissolution. The greatest miracle is that of explaining the truth and to make man realize it. What is the Truth? To know the truth about Life, we have to understand the influence of Time. Individual living entities exist during their own LifeTime while the vital principle that animates all Life remains imperishable, immortal, eternal, and unchanging. Time is defined as the duration in which things are considered as happening in the past, present, or future. Time is the measurement of duration, the period between two events during which something exists, happens, or acts. This concept of Time demands that we must make a fundamental distinction between static and dynamic events. Static is the term used to describe a body, mass, or force that is at rest or in equilibrium and hence it is inactive, stationary, not moving, or progressing. Life is a dynamic event in which the object called the living thing exists by a tendency towards change or productive activity. Life requires the presence of a vital, energetic, animating principle that maintains the equilibrium called existence while responding to a flow of events that measure the duration of the existence of that living thing. In my view, Death is also a dynamic event and it is not a static event as the change called Death inevitably flows to cause Rebirth. The flow of Life must be synchronized with the flow of Time for both of them to proceed until Eternity. I describe Spiritualism and Spirituality as the potency that generates Peace, Harmony, and Tranquility in the Time and Life Interactions to provide the Living Experience that is dependent upon Peace, Harmony, and Tranquility. To know this, we may have to know about the Cyclical Changes of Matter, and the Cyclical Flow of Time. Chemistry is the Science that would give us the understanding of Living Matter and the Cyclical Changes that are caused by Chemical Reactions. In the study of Life, Chemistry is the Science that describes the nature of ‘Spiritual Interactions’. The ‘Spiritual Interactions’ between Time and Matter establish, support, and preserve the existence of Life on this planet Earth.
MATTER – CHEMICAL ELEMENTS AND CHEMICAL COMPOUNDS :
HENNING BRAND(c. 1630-c. 1710), GERMAN ALCHEMIST WHO DISCOVERED PHOSPHORUS DURING c.1669 or 1674. I WOULD DESCRIBE CHEMISTRY AS THE SCIENCE OF SPIRITUAL INTERACTIONS.
ROBERT BOYLE (1627-1691)THE FATHER OF MODERN CHEMISTRY. Anglo-Irish Physicist and Chemist who separated the Science of Chemistry from Alchemy. He gave the first precise definitions of a Chemical Element, a Chemical Reaction, and Chemical Analysis. He discovered Boyle’s Law(Gas Laws).
All ‘Matter’ is composed of fundamental materials called Chemical Elements. A substance that cannot be decomposed into simpler substances by ordinary chemical processes is by definition an Element. There are about 88 ‘naturally’ occurring Elements, and about 20 Elements are used in measurable amounts by most living organisms. Phosphorus is an essential Element to all Life as it is a component of DNA and RNA that make up the genetic material of all cells and control reproduction of both the cell and the organism. Phosphorus is part of the energy storage and utilization system at the cellular level. In addition, Carbon, Hydrogen, Nitrogen, Oxygen, Iron, Calcium, Potassium, Magnesium, Cobalt, Cadmium, Copper, Manganese, Zinc, Molybdenum, Boron, Sodium, Chlorine, Fluorine, Iodine, Sulfur, and Chromium are all essential to one form of life or another. Elements can combine with one another to form a wide variety of more complex substances called Chemical Compounds. A Chemical Compound is a substance in which two or more Elements are joined by Chemical Bonds. A Chemical Compound can be created or broken down by means of a Chemical Reaction but not by mechanical or physical separation techniques. It helps to make the distinction between Mixture and Compound. Most naturally occurring Matter represents Physical Mixtures of Chemical Compounds that could be separated using simple physical techniques. While the number of known Elements is small, the number of possible Compounds is almost ‘infinite’; perhaps a million or more Chemical Compounds are known to exist. When two or more Elements combine to form a Compound, they lose their separate identities, and the product called Chemical Compound has characteristics quite different from those of the constituent Elements. For example, the Common Salt or Sodium Chloride is a combination of the highly reactive metallic element Sodium(Na) and the poisonous gas Chlorine(Cl). The unique taste and flavor imparted by Salt cannot be discovered by studying the physical and chemical properties of Sodium or Chlorine. Elements in Compounds always are combined in definite proportion. For instance, a molecule of Water is always made up of two Hydrogen(H) atoms and one Oxygen(O) atom. Again, I would like to pay attention to the fact of two gaseous elements, Hydrogen, and Oxygen with quite different physical and chemical properties can combine to form the Compound Water which has altogether different properties from either Hydrogen or Oxygen. The simple, pure, original, and sweet taste imparted by Fresh Water cannot be discovered in its constituent Elements. I have mentioned that the Element Phosphorus is basic to all Life. Phosphorus is discovered in c.1674 by Hennig Brand. It is an extremely poisonous, yellow to white, waxy, solid substance. When exposed to air, Phosphorus ignites spontaneously. Some of the commercial uses of Phosphorus include the making of detergents, toxic nerve gases and explosives. We have to learn to make the distinction between Chemical Elements and Chemical Compounds and apply this understanding to know the nature of relationship between things. Calcium Phosphate is the principal material found in bones and teeth. Adenosine Triphosphate or ATP is the fundamental energy source in living things. It is very understandable that all Matter is composed of units called Atoms and the physical structure of Atom is well-known. We have to be very careful and avoid deriving understanding about Life and Living Matter from the descriptive knowledge derived from Quantum Physics. To understand the nature of living experience, we need Chemical Molecules and Chemical Compounds whose qualities and characteristics may not be discovered from the study of Nuclear Physics. The phenomenon of creating and breaking down Chemical Compounds in living organisms is known as Metabolism. A Chemical Compound’s smallest units are, Molecules, and Ions. A Molecule can exist in the free state and still retain the characteristics of the Element or Compound; a Molecule can be formed by an Element when it consists of one Atom, or two, or more similar Atoms; a Molecule can be formed by a Compound when it consists of two or more different Atoms. The term ‘Ion’ is used to describe an Atom or Molecule bearing an electric charge as a result of having a number of negative electrons unequal to the number of positive protons in its nuclei. ‘Ionization’ is the process that describes the formation of ‘Ions’ from neutral Atoms or Molecules. ‘Ions’ that are positively charged are known as ‘Cations’, and that are negatively charged are known as ‘Anions’. Simple ‘Ions’ consist of a single charged Atom; double, triple, or even higher positive or negative charges are possible. Oxidation of Hydrogen removes its single electron and gives H+ or cationic Hydrogen which contains no electrons and it has a nucleus which is composed of one proton. This cationic Hydrogen plays a particularly important role in the Acid-Base Chemistry of the human organism with many reactions exchanging protons between soluble molecules. The internal environment of a living cell includes Hydrogen, Potassium, Sodium, Magnesium, Calcium, Chloride, Sulfate, Phosphate and several organic acid ‘Ions’. The chemical events collectively called ‘Metabolism’ require the concentration of Hydrogen Ions and electrolytes to remain within narrow limits in the tissue cells and in the fluid which bathes them. The term ‘pH’ or ‘Acidity’ is a measure of the Hydrogen Ion concentration and a reading level of 7 indicates ‘Neutral’. Human life is possible only if the Hydrogen Ion concentration of body fluid is kept within a narrow range. In health, a blood Hydrogen Ion concentration of 36 – 44 nmol/Liter or pH level of 7.37 – 7.45 is maintained by several closely integrated but widely differing mechanisms.
THE CHEMICAL ELEMENTS AND CHEMICAL COMPOUNDS OF LIFE :
HENRY CAVENDISH(1731-1810), British Chemist and Physicist noted for his discovery of Hydrogen, a gaseous Element during 1766. French Chemist Lavoisier named the gas Hydrogen in 1783. Hydrogen is the most abundant element in the universe and it is the major fuel in fusion reactions of the Sun. However, this gas in its free state is very rare in our planet Earth.
Hydrogen, the most abundant Element in the universe is present in its diatomic, molecular form. Hydrogen is important for the formation of Stars. In this photo image, NGC 604, a giant region of ionized Hydrogen in the Triangulum Galaxy is seen.
Hydrogen makes up most of the mass( over 90%)of the universe and about 75 % of natural Matter by number of Atoms.Naturally occurring atomic Hydrogen is rare on Earth because Hydrogen readily forms covalent Compounds with most Elements. Hydrogen is present in the Water Molecule and in most Organic Compounds found in living organisms. Hydrogen forms a vast variety of Compounds with Carbon that are called Hydrocarbons.
To understand Life, we have to know about Hydrogen as it is the fuel that Sun expends in its role as the Cosmic source of Energy that supports the biological existence of all terrestrial organisms. Man exists on the surface of planet Earth not on account of the merit of his physical, or mental work and effort. Man has no direct access to this source of energy produced from Hydrogen fuel. If Hydrogen is important to support the existence of Life, we have to understand the nature of ‘Spiritual Interactions’. Secondly, Hydrogen is important as it is required to form the Water Molecule. However, Oxygen, a colorless, odorless, tasteless gas, is the most abundant Element at the surface of the Earth. In the terrestrial environment, Oxygen accounts for about half of the mass of the Earth’s crust, 89% of the mass of the oceans, and 23% of the mass of the atmosphere or 21% of its volume. Oxygen makes up about two-thirds of the human body. It is a vital substance which supports vital functions. Among Chemical Elements used by human body, Oxygen has the highest electronegativity and electron affinity. Oxygen can form ‘Anion’ with a double negative charge by accepting electrons from a donor like Hydrogen. Most of the Earth’s rocks and soils are principally compounds of Oxygen with Silicon and other metals. It is well understood that most organisms depend on Oxygen to sustain their biological processes. Biological Oxidation-Reduction Reactions are ultimately the sources of energy for the higher plants and animals. While speaking about the importance of Oxygen in the biosphere, we must recognize that Oxygen is responsible for natural decomposition of all organic material. Waste products from the activity of the living organisms, dead plants and animals decompose or oxidized through the agency of microorganisms. Thus, Oxygen plays a key role both in its support of important processes of Life and Death. Organic decay and decomposition is of fundamental importance for Life to renew itself and to be reborn and to cause rebirth. The study of ‘Spiritual Interactions’ must include the study of Life and Death.
Joseph Priestley and Karl Scheel were the first to isolate the gaseous Element during 1773-74 which was named by Antoine Laurent Lavoisier as Oxygen. It is a colorless, odorless, tasteless gas, and is the most abundant Element found on planet Earth.
Oxygen makes up about 90% of Water, two-thirds of the human body, and 20% by volume of Air. Normal atmospheric Oxygen is a diatomic Molecule.
The common Chemical Reaction in which Oxygen unites with another substance is called Oxidation.Combustion or rapid oxidation, the burning of s substance may generate light and heat. The process called Oxidation need not involve the generation of light and heat. Oxygen itself does not burn. The Respiration of plants and animals is a form of Oxidation that is essential to the liberation of the energy stored in such food materials as Carbohydrates, Fats, and Proteins. Oxygen is necessary to sustain Metabolism which primarily involves the Oxidation-Reduction Chemical Reactions. If the Oxygen concentration were to drop to about half its value in the atmosphere, humans could no longer survive. The loss of Oxygen is critical as the human body has no means of storing Oxygen. Because the human body stores no Oxygen, any interference with breathing and ventilation that lasts more than a few minutes can cause Death.
Dr. Daniel Rutherford(1749-1819), Professor of Medicine & Botany, Edinburgh University, Scotland, discovered Nitrogen in 1772. Joseph Priestley and Henry Cavendish in England, and Carl W. Scheele in Sweden also get credit for the discovery of Nitrogen. The French Chemist Antoine Lavoisier proved that it is an Element.
On planet Earth, Nitrogen, the most abundant uncombined Element occurs as the diatomic molecule. Atmospheric air is 78.06% Nitrogen gas by volume. Nitrogen is an important component of Protoplasm or Living Matter. It is very remarkable to note that one type of organic molecule with a nitrogenous base plays a variety of roles in support of living functions.
Adenosine Tri Phosphate or ATP is a Nucleotide; the monomeric unit of Nucleic Acid,contains a Purine or Nitrogenous base called Adenosine, a Sugar called Ribose and three Phosphate groups.In most Chemical Reactions of all cells in which transfer of energy occurs, the nucleotide ATP is involved. It functions as a Coenzyme in many enzyme-catalyzed reactions and helps in the performance of chemical, electrical, and osmotic work in animals, plants, and microorganisms.
Cyclic Adenosine Mono Phosphate or cAMP is formed from ATP by the catalytic action of the enzyme Adenyl Cyclase. It controls many important functions in the cell including the ability of the cell to generate electrical impulses and is called “Second Messenger.”It is responsible for the intracellular mediation of hormonal effects on various cellular processes; e.g., Lipid Metabolism, Membrane Transport by opening Ion Channels, and Cell Reproduction.
All living organisms need organic nitrogen compounds such as Proteins, Vitamins like Thiamine and Riboflavin. In nature, Nitrogen from the air is ‘fixed’ by some bacteria and plants. It is then made available to all organisms through ‘Nitrogen Cycle’.
The nonmetallic Element, Carbon is known to man since ancient times. Organic Chemistry is the study of Carbon Compounds. All living organisms contain Carbon Compounds and hence Carbon is the central Element in the Compounds of which organisms are composed. The Carbon Element found in all living organisms is primarily derived from Carbon Dioxide found in atmospheric air or dissolved in water. It occurs both free and combined form in nature and makes up about 1% of the volume of dry air. Carbon Dioxide is a colorless, odorless, tasteless gas. It is the raw material for Photosynthesis in green plants and is a product of animal respiration and of the decay of organic matter. It can cause Death by suffocation if inhaled in large amounts. If this Chemical Compound Carbon Dioxide, a gas that has the potential to cause Death, can impart ‘SWEETNESS’ to a substance that we recognize as ‘SUGAR’, it speaks about the potency that I describe as ‘Spiritual Interaction’ between the Elements of Life.
Plants incorporate Carbon into Carbohydrates and other complex organic molecules by means of Photosynthesis. During Respiration or Cellular Oxidation, living organisms combine Oxygen with portions of Carbohydrate molecule, releasing Carbon in the form of Carbon dioxide and water.
Water Molecules are the simplest and most abundant of all the Molecules found in the living cell. The simplest forms of Life such as the Virus particles may exist as Molecules of Nucleic Acids and need living cells for their replication. Most Chemical Reactions inside the living cell require the aqueous medium. Cells contain 70 to 80% Water. Cell Chemistry involves the study of Reactions in aqueous solutions. But, much of the Water in Cells is not ordinary Water; it is found ‘structured’ in shells surrounding macromolecules, especially proteins. The activities inside the Cell are separated and take place inside compartments that are regulated. It is important to know that most of the Water inside the living Cell is structured and the Chemistry of the living Cell demands separation of events at Molecular level.
ANTOINE LAURENT LAVOISIER(1743-1794), French Chemist and Physicist. He discovered the Composition of Water Molecule and of various other Organic Compounds.
Water Molecule looks very simple and yet it plays a mysterious role inside all living cells. It is essential to Life and its propagation. Its Spiritual nature is revealed by its pure, original, and sweet taste it imparts apart from its role as a Chemical Compound. It is the main mode of transport of many Elements that are needed by the living organisms. Water is the Agent that leaches Nutrient Elements and Compounds from rocks and soils and makes them available for use by plants ,and animals.
THE CYCLICAL FLOW OF TIME :
SUN THE COSMIC SOURCE OF ENERGY SHINES ALL THE TIME. IT IS APPARENTLY AN UNCHANGING EVENT. HOW DOES MAN MEASURE HIS TIME?
The Flow of Time is measured as the duration or the interval between two events; Time exists for man and other living organisms as the measure of the period of duration from Sunrise to Sunset that causes an environmental change; the alternating periods of Light(DAY) and Darkness(NIGHT). Earth’s Rotational Spin transforms the instant called ‘FUTURE’ into an instant called ‘PAST’ without giving man any choice to know the instant called ‘PRESENT’. Earth’s Revolution brings Seasons that man experiences at regular and constant intervals of Time while man simply exists on the surface of planet Earth with no physical experience of Earth’s Motions through Space.
Things in Nature change with Time. Does Time exert a ‘FORCE’ entirely of its own to change things in Nature? If Time is viewed as a ‘FORCE’, or ‘POWER’, who controls this Force or Power and what are the Laws that operate this Force or Power? The Clocks and Calendars that man has invented create the illusion that we live in a world of mathematically measured segments of Time. Sir Issac Newton(1687) stated that the flow of Time is absolute. Time is looked upon as a flow like a river: It “flows equably without relation to anything external.” Herman Minkowski, a Mathematician, added Time as the Fourth Dimension of three-dimensional Space. Time is seen as a dimension like Height and Width and it gives meaning to events and the order in which they occur. In 1905, while postulating the Theory of Relativity, Albert Einstein had observed that the measurement of Time is affected by the motion of the observer and hence it is not absolute. Gravity affects both Time and Light. The measurement of Time is affected by the gravitational field of each celestial body. The experience of Time on this planet is an illusionary experience and it may not be an absolute experience. Physicists tend to describe Time and Space as the building blocks of this universe. In the context of understanding the relationship between Time and Life, we will be forced to see Time in the internal Biological Clocks that keep all living entities in ‘sync’ with Nature.
The Biological Clock: Every Living System behaves as if it contains a highly dependable ‘CLOCK’. It is a self-sustained internal timing mechanism that controls the ability of an organism to synchronize its existence with events in its internal and external environment.Such Time-Dependent variability in Function is called a Biological Rhythm.
All living things have in their nature a plan for their own dissolution and have the ability to use some unique Time-Dependent biological mechanism that is indissociable from life itself. Biological Rhythms represent the periodic biological fluctuation in an organism that corresponds to and is in response to periodic environmental change. Biological Clock in man measures Time as the Solar Day, the period of Earth’s Rotational Spin relative to the Sun. Such Biological Rhythms that occur once a Day are called Circadian( Latin Circa: About, Di: Day ), Solar Day, Diel, Daily, or Diurnal(Day-Active) Rhythm. The Rhythm is synchronized with an external Time-giving stimulus. Within the 24-Hour Cycle, a person usually sleeps approximately 8 hours and is awake 16 hours. For the health and the well-being of man, the daily alteration of Sleep and Wakefulness is important to maintain optimal physiological functions. Man is conditioned to exist under the influence of Time which is operated on planet Earth by its Rotation on its own axis.
THE CYCLICAL FLOW OF LIFE, MATTER, AND ENERGY :
All living organisms depend upon about 20 naturally occurring Chemical Elements. In order for Life to survive, these Elements must be constantly recycled in forms that plants and animals can use. Nutrient Cycle is the term used to describe the natural processes that keep all the Chemical Elements needed to support Life circulating within the Biosphere or Ecosphere. The far-reaching nature of Nutrient Cycles reveal the Interactions between Time, Life, Death, and Rebirth. Life continues using the process called Rebirth. Death is an important requirement to regenerate Life. The dissolution of individual living entities under the influence of Time is a prerequisite for Renewal of Life and the propagation of Life over the limits imposed by Time.
THE WATER OR HYDROLOGIC CYCLE :
The Water Cycle or Hydrologic Cycle is necessary to the operation of all Nutrient Cycles. The energy for the transportation of Water Molecules is provided by the Sun and it is the Fundamental Basis for all other Time-Life Spiritual Interactions.
Water is important to all life forms for its role in the control of environmental conditions and as it is the main mode of transport of many nutrients; it is the agent that leaches nutrients from rocks and soils and make them available for further use by living organisms.
THE CARBON CYCLE :
The Carbon Cycle clearly illustrates the complexity of relationships involved in the processes of Recycling Nutrient Elements in Nature. Life depends on the interwoven and interdependent relationships of green plants and animals, supplemented by the activities of bacteria, and the constant transport of nutrients within the Ecosystem and within organisms.
The Carbon Cycle describes the exchange of Carbon between living organisms and non-living environment.To maintain Life, an organism not only repairs or replaces( or both ) its structures by a constant supply of the materials of which it is composed but also keep its life processes in operation by a steady supply of energy. Living Systems must be supplied energy on a continual basis. Once spent, the energy for Life cannot be replenished except by further exposure of green plants to Sunlight. The Chemical Elements of Life are continually recycled by such processes as Photosynthesis and Respiration.
THE OXYGEN CYCLE :
Photosynthesis and Respiration are complementary functions and drive the Oxygen Cycle.Oxygen is necessary to sustain Metabolism. Oxygen is also important and is responsible for natural decomposition of organic material, waste products of Metabolism, oxidative decomposition of dead plants and animals through the agency of microorganisms.
Oxygen is equally important for Life and Death as Death must be accompanied by decay and decomposition of organic material to release the Nutrient Elements for further use by other living organisms.
THE NITROGEN CYCLE :
All living organisms participate in the Nitrogen Cycle. It includes the processes and Chemical Reactions involved in producing organic Nitrogen from inorganic Nitrogen and subsequently breaking down organic Nitrogen back to the inorganic form.
The Nitrogen Cycle begins when atmospheric Nitrogen and Hydrogen combine to form Ammonia in a process called Ammonification. The Nitrogen Compounds are made available to plants which combine them with the products of Photosynthesis to form Amino Acids, which are the basic components of plant Proteins. Animals eat plant Proteins, break them down into Amino Acids during the process of digestion, and recombine them to form their own particular forms of Proteins in order to build tissues and organs of their bodies. Through breakdown of waste products, death and decay, organic Nitrogen compounds reenter environment.
THE PHOSPHORUS CYCLE :
Phosphorus recycles more slowly than other Nutrient Elements. Phosphates are taken up by the roots of green plants and used in organic synthesis. They are passed to animals through ‘Food Chains’. Ultimately, Phosphates are released to soil through bacterial and fungal decomposition after the death of an animal.
We need to make the distinction between the Chemical Element Phosphorus and Phosphate the Chemical Compound that supports Life. The Phosphate mineral found in the rocks may have taken millions of years before it became available to plant Life.
ECOLOGY – LIFE AND DEATH SPIRITUAL INTERACTIONS :
Life depends on the interwoven and interdependent relationships between living organisms and the environment. No organism leads a truly independent existence of its own. Each organism lives by either consuming other organisms or the products from other organisms. In a Biological Community, Life and Death have a relationship which has a Spiritual Basis.
Ecology describes the movement of Chemical Elements and Chemical Molecules in nature because of the interrelationships and interconnectedness of organisms that form the ‘Food Chains’. This flow has a cyclical pattern and Life and Death could be described as two stages in this exchange of material and energy between the living and non-living environment. Greek philosopher Heraclitus( c. 535 B.C. – c. 475 B.C.) held that there is no permanent Reality except the Reality of Change. His famous maxim : “You cannot step twice in the same River.” I beg to differ from his view. The permanent Reality describes the unchanging Spiritual Nature of a Chemical Molecule that supports Life and Existence. Water Molecule came into its existence billions of years ago and it still retains its unique and distinctive properties and is entirely unaffected by the influence of Time while it undergoes both physical and chemical changes in its Interactions. I seek to describe Spirituality in the unchanging nature of Chemical Molecules that operate the dynamic events of both Life and Death. If Life involves a series of Chemical Reactions such as the Redox or Oxidation-Reduction Chemical Reactions, the same dynamic process continues into Death causing changes to promote Regeneration, Rejuvenation, Renewal, and Rebirth. Spiritualism could be the Dynamic Force that promotes Peace, Harmony, and Tranquility in the material transformations of Life and Death.
Dr. R. Rudra Narasimham, B.Sc., M.B.B.S.,
Kurnool Medical College, Kurnool, Andhra Pradesh, India,
M.B.B.S. Class of April, 1970.
Biographical Information:
1. Place of Birth: Mylapore, Madras City, Chenna Patnam, Chennai, Madras State, Tamil Nadu, India. Born Hindu(Brahmin, Niyogi, Smartha), Telugu-Speaking.
2. Date and Place of Marriage: January 29, 1973. Town Congregational Church, Cuddapah, Kadapa District, Andhra Pradesh, India.
SPIRITUALISM – THE MOLECULAR BASIS OF SPIRITUALITY :
The molecules and processes responsible for energy acquisition, energy manipulation, growth and reproduction are basically similar in all life-forms. To understand life, consideration must be given to describe the molecules that determine its structure and to the ways in which molecules are organized. The Molecular Basis of Spirituality describes the organization of molecules that is responsible for the coordination of living functions and living activities of life-forms. Spiritualism involves the capacity or capability to organize molecules to establish the reality of biological existence by any life-form. To explain the Molecular Basis of Spirituality, I would begin with the simplest life-forms that we know.
THE FOUNDERS OF VIROLOGY – THE STUDY OF VIRUSES :
Dmitri Ivanovsky( Dmitri Iosifovich Iwanowski ), Russian Botanist in 1892, discovered the filterable nature of a very tiny agent that causes Tobacco Mosaic Disease.
Martinus Beijerinck, the Dutch Microbiologist in 1898 named the mysterious infectious agent that causes Tobacco Mosaic Disease as ‘VIRUS’.
I am glad to pay my respectful tribute to Dmitri Ivanovsky, Russian Botanist, and to Martinus Beijerinck, the Dutch Microbiologist, the founders of Virology, the Study of Viruses. Ivanovsky studied the Tobacco Mosaic Disease during 1892. By conducting experiments he had demonstrated that the disease is caused by a filterable agent smaller than bacteria. In 1898, Beijerinck independently replicated Ivanovsky’s experiments and found that the infectious agent could only reproduce by infecting leaves of the Tobacco plant. He named the mysterious infectious agent as Tobacco Mosaic Virus- the first Virus recognized.
THE STUDY OF VIRUSES, VIRIONS, VIROIDS, AND VIRUSOIDS :
Virus is a complex, molecular life-form that blurs the boundaries of living and non-living material.
Viruses are small masses of material( 100 – 2,000 angstrom ), complex molecular life-forms that blur the boundaries of living and non-living material. Most Viruses are smaller than the wavelength of visible light. They are extremely small and can only be seen with an electron microscope. As compared to light microscope, electron microscope can increase magnification from 1,000 – 2,000 diameters to around 300, 000 diameters. Viruses are 1,000 times more plentiful in water than originally suspected and hence Viruses could be the most numerous life-forms on Earth. Many hundreds of different types of Viruses exist and all of them need living cells to serve them as hosts. Viruses can only complete their life cycles as parasites as they reproduce only within the cells of their hosts, upon which they depend for many of their fundamental life processes. While many Viruses are harmless to their hosts, certain Viruses are responsible for important diseases of humans, animals, and plants. Many Viruses are known to man by the specific disease entities that they cause: Smallpox, Chickenpox, Measles, Mumps, Yellow fever, Polio myelitis, Rabies, Influenza, and the Common Cold. All of us without any exception would get the chance of experiencing the bouts of one or the other Viral infections.
The DNA of Herpes Virus particle is enclosed by an icosahedral(20-sided) shell of 162 protein units, or capsomers, and by an outer spiked lipoprotein envelope. It causes infectious diseases in man like Chickenpox and Shingles.
A complete virus particle or Virion consists of one molecule of Nucleic Acid, single or double-stranded, either DNA or RNA depending on the specific Virus. It has a protein coat called Capsid which consists of a specific number of protein molecules or Capsomers in a definitive arrangement. In some Viruses, the outer coat has lipid(fat) and carbohydrate. The protein coat helps the survival of the Virus while it exists outside a living cell. The protein coat is also concerned with the mechanisms by which the Virus enters and infects the host cell.
To understand the concept of Spiritualism as a functional relationship that generates Peace, Harmony and Tranquility, we must know the nature of biotic interaction called Parasitism that causes Disease. Millions of human lives have perished due to the scourge of Viral Diseases that afflict humankind. This Retrovirus called Human Immunodeficiency Virus(HIV) is responsible for Acquired Immune Deficiency Syndrome or AIDS.
During the stage of its life cycle, when the Virus is free and infectious, the virus particle or Virion is inert, and does not carry out the usual functions of a living entity, such as reproduction or growth in numbers. The propagation of a Virus requires the internal environment of a complete cell, including its biochemical machinery. The Virus loses the protein coat upon entry into a cell, after which the genetic material of the Virus reproduces using materials made by the host cell. The Virus leaves the host cell surrounded by the protein coat, the characteristics of these protein molecules are determined by the genes in the Virus, but the protein molecules are synthesized by the host cell. Viruses are often described as “naked genes” which have discarded all other attributes of complete cells. The Virion or virus particle contains the knowledge or biological information that is needed for its replication. However, to perform that reproductive function, a Virus needs the host cell’s chemical energy, and protein-and nucleic-acid synthesizing ability.
Viroids and Virusoids are the smallest and simplest form of all recognized Viruses and Self-replicating Molecules.They lack the protective shell of protein coat that most other Viruses have.
Viroids and Virusoids are the smallest and simplest form of all recognized Viruses and Self-replicating Molecules. Viroids are composed of nothing more than a single circular strand of genetic material and cause major disease in plants. Since Viroids lack the protective shell of protein, they do not even spread easily from one cell or plant to another. The genetic material of Viroid is RNA which has a length of only a few hundred ribonucletids(200-400). Viroids are described as molecules of “naked RNA” that are significantly smaller than the genome of the smallest Virus. They are also called ‘subviral particles’. Viroids/Virusoids “infect” other Viruses, and use the replication process of the host Virus to replicate themselves instead. Viroids are responsible for a number of serious diseases of economically important plants like the Coconut Palm and Chrysanthemums. Episomes are pieces of self-replicating genetic molecules found in some bacterial cells. These are similar to Viruses except for the fact that they only reproduce themselves when their host cells do, whereas Viruses reproduce themselves hundreds of times and often generate the signs and symptoms of the infectious disease they cause in the host.
RNA MOLECULE AS GENETIC MATERIAL :
The only human disease caused by a Viroid is HEPATITIS- D. The Viroid is enclosed in Hepatitis B Virus Capsid. Viroids use different strategies for encouraging host Viruses/cells to replicate its RNA molecule.
The RNA-containing Viruses are unique among living systems. They use RNA as their primary genetic material. Retroviruses produce the enzyme called RNA-directed DNA Polymerase or Reverse Transcriptase, which can make a DNA molecule from the Viral RNA molecule. This DNA molecule formed from RNA then serves as the principal genetic molecule within the infected, host cell. Retrovirus uses a life process that is termed ‘reverse transcription’. Two Retroviruses are associated with human leukemia which are Cancer of T-cells. The Retrovirus known as Human Immunodeficiency Virus or HIV is responsible for Acquired Immunodeficiency Syndrome or AIDS.
THE NUCLEIC ACID MOLECULE – THE ESSENCE AND EXISTENCE OF LIFE :
The Influenza Virus has the ability to cause pandemic(world-wide)infection of humans. The pandemic of 1918 is estimated to have killed 21-22 million people worldwide. The Virus got its name from the word “INFLUENCE” from an observation made more than 400 years ago that epidemics of respiratory illness occurred under the “influence” of planets and other astrological events. The term ‘spiritualism’ or ‘spirituality’ does not describe the ‘essence’ or character of this Viral Nucleic Acid Molecule.
Nucleic Acids are organic substances that are characteristic of all living things. These organic molecules are not found in nature except as components or products of organisms. They are called macromolecules; molecules of molecular weight greater than 10,000 daltons or 10,000 times the weight of a Hydrogen atom. These molecules are long chains or polymers that consist of chains of smaller units called monomers. Each Nucleic Acid chain is composed of subunits called nucleotides, each of which is composed of a specific sugar molecule( Deoxyribose or Ribose ), a molecule of Phosphoric Acid, and a molecule of one of four organic bases: Adenine(A), Guanine(G), Cytosine(C), and Thymine(T). The two chief types of Nucleic Acid are DNA( Deoxyribo Nucleic Acid ), and RNA( Ribo Nucleic Acid ). DNA contains the sugar deoxyribose and RNA contains the sugar ribose, and the base Uracil(U) instead of Thymine(T). The specific sequences of nucleotides constitute the genetic information of the life-form. Each three-nucleotide sequence specifies one particular amino acid. The long sequences of nucleotides thus correspond to the sequences of amino acids in the proteins that are synthesized. In order to be expressed as protein, the genetic information is carried to the protein-synthesizing machinery called Ribosomes found in the cytoplasm of the cell. Forms of RNA mediate this process and are important in the expression of the genetic code contained in the DNA for the synthesis of proteins. Although the triplet nucleotide code seems to be universal, the actual sequences of the nucleotides vary according to the species and individual organism. The Nucleic Acid Molecules, DNA/RNA is the substance of heredity; it carries the ‘essence’ or character of an organism from one generation to next generation. But, in the study of Viruses we have found that this ‘essence’ is not displayed until its ‘existence’ is supported and is established in a complete living cell. The Nucleic Acid Molecules do not have the capacity or capability of acquiring energy from their external environment. The Virion or virus particle is inert until it finds a host cell to establish its life as a living thing. The Nucleic Acid Molecules are important to establish the ‘essence’ of an organism and I find the characteristics called ‘Spiritualism’ or ‘Spirituality’ in the functional organization of those Molecules that establish the ‘existence’ of a living entity.
THE MOLECULAR BASIS OF SPIRITUALITY :
Smallpox or Variola was one of the worst scourges ever to afflict human beings. The Smallpox Vaccine developed by Dr. Edward Jenner, British Surgeon in 1796 was the first successful Immunization against any Infectious Disease or Agent. In October 1979, the World Health Organization(WHO) declared that the world is Smallpox Free. Spiritualism and Spirituality seek to establish Peace, Harmony, and Tranquility in all functional Biotic Interactions within the Individual and within the Biotic or Biological Community.
The purpose and goal of Spiritualism or Spirituality is that of generating Peace, Harmony, and Equilibrium in all functional relationships within the Individual and between members of the Biotic or Biological Community. The disease, the disability, the morbidity, and death caused by Viral infections demonstrate the consequences of Biotic Interactions called Parasitism. The functional organization of a variety of Molecules that provide the functional ability called ‘Existence’ that establishes a living entity is the chief attribute of the ground substance found inside the Living, Complete Cell and the viral particles have no such functional organizational capacity or capability. The Spirit or Soul represents the ‘Knower’ of the Function and is the Architect of Molecular Organization that causes ‘Existence’. The role of various other Molecules, the Molecules concerned with Life, found in living cells will be given further consideration in my next blog post to demonstrate the ‘spiritual’ nature of the Protoplasm, the ground substance, the living material, or living matter that constitutes Life.
Dr. R. Rudra Narasimham, B.Sc., M.B.B.S.,
Kurnool Medical College, Kurnool, Andhra Pradesh, India,
M.B.B.S. Class of April, 1970.
Biographical Information :
1. Place of Birth : Mylapore, Madras City, Chenna Patnam, Chennai, Madras State, Tamil Nadu, India. Born: Hindu, Brahmin(Niyogi-Smartha), Telugu Speaking.
2. Date and Place of Marriage : January 29, 1973, Congregational Town Church, Cuddapah, Kadapa District, Andhra Pradesh, India.
A diagram of a typical prokaryotic cell. This diagram, made in Adobe Illustrator, is an improved version of a similar diagram, Image:Prokaryote cell diagram.svg, which was also made by LadyofHats. Besides general appearance changes, this version adds plasmids and pili, and notes that DNA is circular. (Photo credit: Wikipedia)
SPIRITUALISM – THE CELL THEORY OF SPIRITUALITY :
In Biology, cell is the basic or fundamental unit of structure, function, and organization in all living things or it is the building block of life. Let me begin with my respectful tribute to some of the people who contributed to ‘The Cell Theory’, one of the foundations of Biological Sciences. Cells were first observed in the 17th century shortly after the discovery of the microscope. Robert Hooke, british curator of instruments at The Royal Society of London, during 1665 coined the word cell. Dutch microscopist Antonie Van Leeuwenhoek(1632-1723) made over 247 microscopes and examined microorganisms and tissue samples. He gave the first complete descriptions of bacteria, protozoa( which he called animalcules ), spermatozoa, and striped muscle. He also studied capillary circulation and observed Red Blood Cells.
Robert Hooke, british curator of instruments at The Royal Society of London coined the term cell during 1665.
Dutch microscopist Antonie Van Leeuwenhoek(1668-80) studied capillary circulation and observed Red Blood Cells.
Improvements in microscopy during early 19th century permitted closer observation and the significance of cells had received better understanding. Matthias Jakob Schleiden(1838), german botanist, Theodor Schwann(1839), german physiologist, and Rudolf Virchow(1855), german pathologist, and others made important contributions to The Cell Theory that describes cell as the building block of all Life.
Schleiden, Professor of Botany, The University of Jena studied plant structure under the microscope, published “Contibutions to Phytogenesis”(1838). He had also published the two-volume text of ‘Principles of Scientific Botany’.
Schwann founder of modern Histology extended the Cell Theory of Plants to animals in his ‘Microscopic Researches into Accordance in the Structure and Growth of Animals and Plants(1839).
Schwann discovered Myelin Sheath covering peripheral axons, now termed Schwann Cells. He coined the term ‘Metabolism’ for the chemical changes that take place in living tissues.
Rudolf Virchow,german pathologist in 1855 coined the biological dictum “OMNIS CELLULA E CELLULA” – All living cells arise only from pre-existing living cells.
The Cell is the smallest unit in the living organism that is capable of carrying on the essential life processes of sustaining metabolism for producing energy and reproducing. Many simple, small, single-celled organisms like Protozoa perform all life functions. In higher, complex, bigger, multicellular organisms, groups of cells are structurally and functionally differentiated into specialized tissues and organ systems. Thus, The Cell Theory includes the following foundational principles of the Biological Sciences:
1. All living things are made up of cells. Cell is the most elementary or basic unit of Life.
2. Cell is a fundamental unit of structure, function, and organization in all living things including plants and animals.
3. Cells only rise from division of previously existing cells.
4. All cells are similar in composition, form, and function. All cells are basically the same in chemical composition( in spite of variations ) in organisms of similar species. For example, all the solid tissues in the human body can be shown to consist largely of similar cells; differing it is true, but that are essentially similar to an Ovum.
5. The cells exhibit functional autonomy. The activity of an organism depends on the total activity of ‘INDEPENDENT’ cells.
6. Energy flow( metabolism and biochemistry ) occurs within cells.
7. Cells contain hereditary, biological information(DNA) which is passed from cell to cell during cell division.
THE CELL THEORY OF SPIRITUALITY :
The basic or fundamental unit of life in the human organism is derived from the fertilized egg cell that eventually develops into a complete organism. The most significant feature of similarity between the cells of the human body is the presence of a soft, gelatinous, semi-fluid, granular material inside the cell. This substance known as Protoplasm or Cytoplasm, or Cytosol is similar to the ground substance found in the Ovum or the Egg Cell. This viscous, translucent, colloidal substance is enclosed in a membrane called Plasma Membrane or Biological Membrane. A small spherical body called nucleus is embedded in the Protoplasm of the cell. The two essential features of any living cell in the human body are that of the presence of Protoplasm and the nucleus.
Human Ovum Structure – The Cell Theory of Spirituality is based upon the Substance, Structure, Form, Organization, Function, Action and Interactions of this Single Fertilized Egg Cell that eventually develops into a complete human organism.
THE SPIRITUALITY OF SUBSTANCE, FUNCTION, ORGANIZATION, ACTION, AND INTERACTIONS :
To establish the biological existence of the human organism, I add the concept of Spiritualism and Spirituality to The Theory of Cell. The Single Fertilized Egg Cell has ground substance that is of Spiritual nature and the Spiritualism and Spirituality consists of the following functional, and organizational characteristics:
1. The Cell is Conscious of its own existence and knows its internal condition and knows it external environment.
2. The Cell is Intelligent and it has the Cognitive abilities like perception and memory to acquire information, to retain information, to recall information, and to use information in the performance of its complex tasks in a sequential manner.
3. The Cell has the ability to show characteristics such as mutual cooperation, mutual tolerance, and display functional subordination and subservience while being independent.
4. The Cell grows, divides, and develops into a complete organism while it acquires substances and energy from an external environment and it continuously transforms matter to build matter of its own kind for its own benefit to sustain its existence with its own identity, individuality while the Organism represents a social group or a biological community. The Spiritual nature of the substance brings this functional harmony and unity by bringing together its Essence and Existence.
The theoretical claims about Spirit and Soul, the religious and philosophical doctrines of Spiritualism and Spirituality must be verified using The Cell Theory that defines the human organism. To describe Soul or Spirit as nonmaterial Self will not help man to know the real or true man.
Principle of ECG formation, fast Deutsch: Prinzip der EKG-Darstellung, schnell (Photo credit: Wikipedia)
SPIRITUALISM – THE BIOLOGICAL BASIS OF SPIRITUALITY :
From the beginning of human history, the ideas and concepts about Spiritualism and Spirituality included a desire to find Peace, Harmony, and Tranquility in the living human experience and it is concerned about the experience of Happiness, Joy, and Bliss which is described as ‘ANANDA’ in Sanskrit language. Thinkers have contemplated that Spiritualism or Spirituality may involve a potency that is associated with an intelligent, immaterial substance called Spirit. The term Soul is often used to describe the immortal, immutable aspect of man who is separate from his body. The term Spirit is used to describe a thing that may have an independent existence of its own apart from the physical body and it may survive after the death of the body. The ideas or concepts about Soul or Spirit appear to be valid and upon verification, I seek the existence of Soul or Spirit in a substance that is basic to life activities, and in a material that is responsible for all living processes. I, therefore, propose that the understanding of the true or real nature of this ground substance of all living matter will help man to discover Peace, Harmony, and Tranquility in all of his internal and external relationships while man exists in a physical environment as a member of a social group, social community, and Society. In this blog post, I would like to pay my respectful tribute to Jan Evangelista Purkinje and Hugo Von Mohl for their great contribution to the scientific understanding of the living substance, living material, and living matter.
JAN EVANGELISTA PURKINJE – JAN EVANGELISTA PURKYNE :
Jan Evangelista Purkyne(Czech name), Jan Evangelista Purkinje(German name)also known as Johannes Evangelist Purkinje, b. December 17, 1787, d. July 28, 1869. The pioneer Czech experimental Physiologist whose investigations in the fields of Histology, Embryology,and Pharmacology helped create a modern understanding of the eye and vision, brain and heart function, mammalian reproduction, and the composition of cells.
Purkinje conducted his research on human vision at the University of Prague and later on, he served there as a Professor of Physiology(1850-69). He went to Germany and was appointed the Chair of Physiology and Pathology(1823-50) at the University of Breslau, Prussia. There Purkinje created the world’s first independent Department of Physiology(1839) and the first Physiological Laboratory(Physiological Institute, 1842). He is best known for his discovery of large nerve cells with many branching extensions found in the cortex of Cerebellum of the brain(Purkinje Cells, 1837). He discovered the fibrous tissue that conducts electrical impulses from the ‘pacemaker’ called Atrioventricular node or A-V node along the inside walls of the ventricles to all parts of the heart to help in Cardiac contractile function(Purkinje Fibers, 1839). In 1835, he invented and introduced the scientific term ‘Protoplasm’ to describe the ground substance found inside young animal embryo cells. He discovered the sweat glands of the skin(1833); he discovered the nine configuration groups of Fingerprints used in biometric identification of man(1823); he described the germinal vesicle or nucleus of the unripe ovum that now bears his name(1825), and he noted the protein digesting power of pancreatic extracts(1836).
Purkinje Fibers and Cardiac Contraction. The spiritual nature of protoplasm brings functional unity among the cells, tissues, and organ systems of the human body.
Purkinje Nerve Cells or neurons found in Cerebellum of brain.Protoplasm is a spiritual substance that brings functional unity between the cells, tissues, and organ systems of the human body.
Fingerprint Identification: By using the current biometric identification technologies, each human being including identical twins could be known as specific individuals. Protoplasm is a spiritual substance that establishes the Individuality while the genome presents the morphological appearance and physical identity of man.
HUGO VON MOHL :
Hugo Von Mohl, b. April 08, 1805, d. April 01, 1872, German Botanist noted for his research on the anatomy and physiology of plant cells.
Hugo Von Mohl named the granular, colloidal material that made up the main substance of the plant cell as “Protoplasm” in 1846. Purkinje had invented the word, but Hugo gave more clarity, understanding, and knowing the nature of this ground substance. He viewed cell as an “elementary organ” and in Physiology he explained Protoplasm as an organ of Motion or Movement, Nutrition, and Reproduction. It is the preliminary material in cellular generation. He was the first to propose that new cells are formed by division of preexisting cells and he had observed this process of Cell Division in the algal cells of Conferva glomerata. His observations are very important to understand the Cell Theory that explains cells as the basic building blocks of Life. He was the first to investigate the phenomenon of the stomatal openings in leaves.
PROTOPLASM – THE GROUND SUBSTANCE OF SPIRITUALISM AND SPIRITUALITY :
The Ground Substance of Spiritualism and Spirituality. The vital characteristics, the animating principles of Protoplasm could be known by observing Amoeba proteus. The Living Substance works as an organ of Motion or Movement, as an organ of Nutrition, and as an organ of Reproduction to generate new cells which have a life span of their own. In these physiological functions, I describe the characteristics such as Cognition, Consciousness, Memory, and Intelligence which have a Spiritual role as they bring functional unity and harmony in the interactions between different parts of the same individual organism while it exists in an environment as a member of a biological community.
Protoplasm is a complex, viscous, translucent solution of such materials as salts and simple sugars with other molecules, mostly proteins and fats, in a colloidal state, that is dispersed but not dissolved in one another. Carbon, Hydrogen, Oxygen, and Nitrogen constitute more than 90 percent of Protoplasm. It exhibits properties such as Protoplasmic Streaming or Cytoplasmic Streaming or Motion that is called “Amoeboid Movement.” It has the intrinsic power to change its shape and position. It has the power of Nutrition by which it can attract and obtain the materials necessary for its growth and maintenance from surrounding matter/environment. These functions involve acquiring, processing, retaining, and using information to perform tasks in a sequential manner for a predetermined purpose and hence describe Consciousness, Memory, and Intelligence. The terms Soul and Spirit belong to the materialistic realm where the Physical Reality of man’s biological existence is established. I have not yet discovered any good reason to use the terms Soul and Spirit as a metaphysical or transcendental Reality.
SPIRITUALISM – THE COGNITIVE SCIENCE OF SPIRITUALITY :
The term cognition is derived from Latin word ‘cognitio’ which means knowledge which is related to the Latin word ‘cognoscere( co-, together + gnoscere, know) which means the act or process of knowing. Cognitive Science involves the study of all human activities related to knowledge. These activities include attention, creativity, memory, perception, problem solving, thinking, and the use of language. Cognition is the process involved in knowing, or the act of knowing which includes awareness and judgment. Cognition is often viewed as a psychological function and its nature is described as the relationship between the knowing mind and external reality. The Cognitive Science of Spirituality that I would like to describe is related to the cognitive abilities of a living cell or living organism; the abilities such as recognition, responsiveness, communication using signals, memory, ability to process, store, retrieve, and use information that could be innate or acquired, the ability of adaptation to changing internal or external environmental conditions, and the fact of awareness of its own existence; the awareness of its internal condition, and the awareness of its external environment.
Amoeba proteus and The Cognitive Science of Spiritualism. To understand the human person as a Spiritual being, we need to know and understand the Spiritual nature of Living Matter or Living Substance and describe its Cognitive abilities.
The purpose of the Cognitive Science of Spirituality is not that of describing a cognitive theory of human personality. The Behavioral Science is primarily involved in the study of stimuli and responses; it observes human activities particularly social behavior and not that of higher mental processes which are not available to direct examination. While Cognitive Science is concerned with mind’s ability to acquire, process, store, and use information, the information processed need not be represented in cortical awareness. Cognitive Psychology does not rely on conscious introspection or mental reflection. The Cognitive Science of Spirituality that I describe does not involve acts of Meditation or mental introspection to discover the spiritual nature of man. I suggest that Spiritualism can be understood without regard to the machinery of brain/mind’s information processing. The organism that we all know as Amoeba( Greek word – ‘Amoibe’ which means change) is a spiritual entity as it is Conscious or Aware of its existence, it shows responsiveness by changing its shape as it likes, it is Intelligent for it uses, processes, stores, retrieves, and uses information to perform its metabolic functions, and it displays abilities such as adaptation and memory of its acquired experience. I tend to view these biological functions and characteristics as an attribute of the spiritual nature of its living substance and this spiritual nature brings functional harmony to sustain its existence as a biological entity.
THE THEORY OF KNOWLEDGE AND THE COGNITIVE SCIENCE OF SPIRITUALISM :
Bertrand Arthur William Russel, b. May. 18, 1872, d. February. 02, 1970. English logician and philosopher, best known for his work in mathematical logic, his advocacy of both Pacifism and Nuclear Disarmament. He received the Nobel Prize for Literature in 1950.
I am not concerned about Bertrand Russell’s skeptical atheist temperament. The Spiritualism that I describe is not about religious faith or belief and the Spirituality that I write about is not concerned with religious practices or rituals. I claim that man is a Spiritual being because of the spiritual nature of his living matter or living substance. It is important to know that Russell was determined not to be beguiled by human pretensions to knowledge. He had never supported unbacked assumptions either about the foundations of knowledge or about what may be said to exist. He endorsed the application of rationality to all aspects of human thought and language. He was seriously concerned with the application of logical analysis to epistemological questions and attacked this problem by trying to breakdown human knowledge into minimum statements that were verifiable by empirical observation, reason, and logic. He was convinced that all knowledge is dependent on sense experience. His primary aim was to inquire with skeptical intent, “how much we can be said to know and with what degree of certainty or doubtfulness.” In 1898, with Trinity Fellow G.E. Moore, he rebelled against Idealism and became an Empiricist, a Positivist, and a Physical Realist or a Materialist. He held that the scientific view of the world is largely the correct view. He addressed the problem of the pretensions of human knowledge in his books, An Inquiry into Meaning and Truth(1940) and Human Knowledge, Its Scope and Limits(1948). His aim was also analytic and he assumed that it is possible to infer something about the world from the language in which it is correctly described. Russell analyzed that language must be used to state its minimum requirements, its atomic facts and avoid the use of descriptive phrases which may postulate the existence of objects. He held that a proposition is a picture of the facts that it asserts and must have in a sense the same structure. He stressed the importance of similarity of structure as a criterion in inferring causal relationships. In a Lecture titled ‘Why I am not a Christian’ given on March 06, 1927, Russell explained the nature of his beliefs about God and Mortality. In his opinion and personal belief, he held the view that Life suitable to Protoplasm could be possible under certain physical conditions like temperature. Russell’s speculative assumption about the existence of Life or Protoplasm is not supported by scientific evidence. He had no scientific data to support his view. The ideal conditions for Life and Protoplasm exist right now and what we know is that Life is always born from previously existing Life. However, he had concluded his Lecture by stating that, “it needs hope for the future……., the future that our intelligence can create.” His assumption that human intelligence is the basis for man’s biological existence is incorrect and is not consistent with the scientific reality about human existence and its nature. At a very fundamental level, man’s ability to acquire energy from an external source in the physical environment does not depend upon his physical or mental work or effort. If green plants with Chloroplasts have the ability to trap Sun’s energy, it could not be attributed to man’s intelligence and the fact of Chloroplasts and their ability is not dependent on man having any kind of intelligence. Russell’s theoretical claims have no relationship with observational evidence and his opinions could be easily refuted for lack of validity. Physical Sciences and Biological Sciences provide accepted body of information about the world and human body. We need to arrange this information into a meaningful pattern and interpret it to describe the reality. The purpose of the Cognitive Science of Spiritualism is to describe and codify observations and experiences to explain the biological basis for human organism in its given environment as an individual, and as a member of a biological community.