The Celebration of Maternal Cytoplasmic Inheritance
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance.
Excerpt: This piece pays tribute to Mother’s Day 2024, focusing on the significance of maternal cytoplasmic inheritance in human creation and existence. The author extols the divine principles of fatherhood and motherhood, which shape life through a three-fold inheritance: the human genome, cytoplasmic inheritance, and the inheritance of the physical and social environment. The author emphasizes the role of the mother cell in bequeathing life, energy, and knowledge, via the mitochondria – the cellular powerhouse. The mother cell also carries unique attributes that, in combination with paternal genes, ensure every human being displays their distinct individuality. The cell’s functionality in acquiring and distributing energy, and its cytoplasmic intelligence, are ascribed to maternal cytoplasmic inheritance.
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic Inheritance.
To celebrate Mother’s Day on Sunday, May 12, 2024, I account for my human existence using the phrase Whole Inheritance which includes the contributions of the Divine Principle, the Father Principle, and the Mother Principle. The term inheritance must include the inheritance of Matter and Knowledge from Mother apart from the genome as the fact of existence needs the support from an external environment at any given time and place.
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic Inheritance.
The Divine Principle ensures the creation of the newborn who arrives in a physical and social environment to exist as an Individual with Individuality, an original, one of its own kind of object without any exceptions.
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance. THE ENTIRE HUMAN ORGANISM IS DERIVED FROM A SINGLE FERTILIZED EGG CELL. HOW IS THE IDENTITY AND INDIVIDUALITY IS ESTABLISHED AND IS KNOWN IN THIS COMPLEX MULTICELLULAR ORGANISM?Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic Inheritance.
The Celebration of Maternal Cytoplasmic Inheritance
The establishment of human existence primarily involves three kinds of inheritance. 1. The Inheritance of the Human Genome, 2. The Cytoplasmic Inheritance which includes the inheritance of cytoplasm and its organelles, the Cell Membrane or Biological Membrane, and 3. The Inheritance of Physical and Social Environment that supports the existence
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance. The Human Genome is just one dimension of the 3-dimensional inheritance.Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic Inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance. Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic Inheritance.
The Inheritance of Cell or Biological Membrane:
Living cells have a corporeal substance called Protoplasm that has the ability of Spiritual Biotic Interactions. The Biological Membrane or Cell Membrane separates the cell from its environment and other living cells present in the environment. Cells use unique proteins, biological molecules and receptor sites to recognize the other living cells and use chemical signals to facilitate the interactions. Such interactions between living cells have the characteristics of consciousness or awareness.
The Functions of Biological Membrane:
1. Protection: It protects the cell from its surroundings or extracellular environment. Plant cell possess wall over the plasma membrane for extra protection and support.
2. Holding cell contents: Plasma membranes hold the semi fluid protoplasmic contents of the cell intact; thus keeping the individuality of the cell.
3. Selective Permeability: Cell membrane allows only selected or specific substances to enter into the cell and are impermeable to others.
Gases like O2 and CO2 can diffuse rapidly in solution through membranes.
Small compounds like H2O and methane can easily pass through where as sugars, amino acids and charged ions are transported with the help of transport proteins.
The size of the molecules which can pass through the plasma membrane is 1-15 A0. This property is responsible for keeping a cell ‘as a cell’, an individual unit.
4. Shape: It maintains form and shape of the cell. It serves as site of anchorage or attachment of the cytoskeleton; thus providing shape to the cell (especially in animal cells without cell wall).
5. Organelles: Cell membrane delimits or covers all sub-cellular structures or organelles like nucleus, mitochondria, plastids, Golgi apparatus, endoplasmic reticulum, microbodies etc. thus protecting them form the surroundings and also helps in maintaining a constant internal environment.
6. Compartmentalization: Cell membrane separate the cells from their external environment and cell organelle from cytosol. It help the cells and their organelles to have their own microenvironments, structural and functional individuality.
7. Cell Recognition: With the help of glycolipids and glycoproteins on its surface, cell membranes are able to differentiate similar cells from dissimilar ones, foreign substances and cells own materials. Cell recognition is useful for tissue formation and defence against microbes.
8. Antigens: Cell membranes possess antigens which determine blood grouping, immune response, acceptance or rejection of a transplant (graft rejection by MHC’s on plasma membrane).
9. Microvilli: They are microscopic finger like projections of plasma membrane present on some cells like intestinal epithelial cells, which are involved in a wide variety of functions, including increasing surface area for absorption, secretion, cellular adhesion etc.
10. Sheaths of cilia and flagella: Cilia and flagella are projections from the cell; made up of microtubules which are covered by an extension of the plasma membrane.
11. Cytoplasmic bridges in plasmodesmata and gap junctions: Plasmodesmata in plant cells and gap junctions in animal cells; meant for intercellular transport and communication, form cytoplasmic bridges between adjacent cells through plasma membrane.
12. Endocytosis and Exocytosis: Bulk intake of materials or endocytosis occurs through development of membrane vesicles or invagination and engulfing by plasma membrane.
Exocytosis: It is reverse of endocytosis that provides for releasing waste products and secretory materials ot of the cells with the help of plasma membrane.
13. Impulse transmission in neurons: The transmission of a nerve impulse along a neuron from one end to the other occurs as a result of electrical changes across the plasma membrane of the neuron
14. Cell metabolism: Cell membranes control cell metabolism through selective permeability and retentivity of substances in a cell.
15. Electron transport chain in bacteria: In bacteria; Electron transport chain is located in cell membrane.
16. Osmosis through cell membrane: It is movement of solvent molecules (generally water) from the region of less concentrated solution to the region of high concentrated solution through a semi permeable membrane. Here the semi permeable membrane that helps in osmosis is the cell membrane. Eg: Root cells take up water from the soil by osmosis
17. Carrier proteins for active transport: They occur in the cell membranes and control active transport of substances. Example, GLUT1 is a named carrier protein found in almost all animal cell membranes that transports glucose across the bilayer or plasma membrane.
18. Plasma Membrane enzymes: Many enzymes are present on the plasma membrane with wide variety of catalytic activity. Example: Red blood cell plasma membranes contain a number of enzymes such as ATPases, anion transport protein, glyceraldehyde 3-phosphate dehydrogenase, protein kinases, adenylate cyclase, acetylcholinesterase.
19. Cell Membrane Receptors: Receptor on the plasma membrane performs signal transduction, converting an extracellular signal into an intra-cellular signal. Membrane possess receptors for hormones, neurotransmitters, antibodies and several other biochemicals.
20. Plasma membrane assisted Cell movements: Undulation and pseudopodia are cell membrane phenomenon involved in cell movement. Amoeba, macrophages and WBCs move with the helps of temporary organelles like pseudopodia. Pseudopods are temporary cytoplasmic projections of the cell membrane in certain unicellular protists such as Amoeba. Some mammalian cells such as fibroblasts can move over a solid surface by wave like undulations of the plasma membrane.
The Divine Principle has to be both male and female and in this article, I present the feminine aspect of Divine Principle as “Whole Angel”, the harmonious blending or coming together of Angel of Beauty, Angel of Mercy, and Angel of Knowledge. My understanding of Mother and Motherhood comes from the study of the building blocks of Life. The most important building block of human life is the fertilized Egg Cell.
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic Inheritance. The newborn baby upon separation from its mother begins life as an independent living entity by initiation of its vital, living functions such as Respiration and Circulation. To survive in physical world, the baby needs the ability to breathe on its own and circulate the vital supply of Oxygen to all tissues and organs of the entire body.HAPPY MOTHER’S DAY, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance. THE DIVINE ATTRIBUTE OF MOTHERHOOD IS THE MATERNAL CYTOPLASMIC INHERITANCE. I DESCRIBE THE CONCEPT OF “WHOLE ANGEL” AS THE HARMONIOUS BLENDING OR COMING TOGETHER OF ANGEL OF BEAUTY, ANGEL OF MERCY, AND ANGEL OF KNOWLEDGE .
The Father and the Mother – The Principles governing Life:
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance
Father is described as the male parent, an ancestor, an originator, and as a Controller. Very often, in the Land of India, God is considered as both the Father and the Mother of all life forms. Mother is described as the female parent and something that is regarded as a ‘Source’. In the Indian tradition, Father may be viewed as the ‘Prime Cause’ and Mother is the Source of ‘Prime Energy’. Mother is the source of energy in performance of all kinds of actions and in accomplishment of all kinds of work. The Mother Principle represents the Endeavor/Work/Effort that makes action possible. If Life is defined as function at the level of biological molecules, Mother represents the Source or the Origin of these organic molecules; Mother is the Source of Energy for the synthesis of these organic molecules; and Mother is the Source of Knowledge that provides the ability of recognition and the ability to use the molecules in a sequential manner to manage the biochemical reactions of these organic molecules to function as Life.
Angel of Beauty – Mother – Source of Life:
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance.Goddess Laxmi is the Divine Provider of Life, Food, and Well-being.
The complex, multicellular human organism begins as a single cell. That single cell is the source of life, energy, and knowledge.
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance. The Biological Dictum states “EX OVO OMNIA” – Everything comes from the Egg.Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance.The Biological Dictum – “OMNIS CELLULA E CELLULA” means all cells from (previously existing) cells.Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance of Life, Energy, and Knowledge.The Law of Biogenesis states that organisms arise only by the reproduction of other organisms. This cell known as Oocyte develops into Human Ovum or Egg Cell which begins the life of a new human organism after an event called Fertilization.
I, as a human organism exist in this world as I arrived from a previously existing ‘Mother Cell’. By repeated cell growth and cell division or replication known as ‘Mitosis’, the human organism grows and develops into a form containing thousands of billions of cells. This process of development is called ‘Morphogenesis’ which involves not only cell growth but differentiation into specialized types of cells. All the tissues and organs of which the human body is composed have originally developed from a microscopic cell known as ‘Ovum’ or the ‘Egg Cell’. This Ovum or Egg Cell may be regarded as a perfect cell and could be described as ‘Mother Cell’. All the solid tissues in the human body can be shown to consist largely of similar cells; it is true that they may differ, but they are essentially similar to an Ovum. The Ovum is a reproductive cell that is adapted to meet the nutritional requirements of the early developmental stages of the embryo. It is always a large cell because it contains sufficient cytoplasmic substance for the development of a self-sufficient embryo. Some of the substance which is packaged in yolk particles contains cell components; typically an Ovum contains sufficient quantities of components for many cells. Thus the Ovum need not grow as it divides; as the nuclei divide, the cytoplasm subdivides until the Ovum consists of a large number of normal-sized cells. By contrast, the male reproductive cells known as ‘Spermatozoa’ contain very little cytoplasm and they cannot further divide into new cells.
THE Source OF Life – Protoplasm:
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance of Life, Energy, and Knowledge.There is similarity between the cells of a man and that of his Mother Cell or Egg Cell called Ovum.Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance.Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance.Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance.
The most significant feature of the similarity between the cells of a man and that of the ‘Mother Cell’ from which he had arrived is presence of a soft gelatinous, semi-fluid, granular material inside the cell. This substance known as ‘Protoplasm’ is similar to that found in the Ovum. The Ovum consists of this viscous, translucent, colloidal substance enclosed in a membrane called Plasma Membrane. A small spherical body called nucleus is embedded in the protoplasm. The protoplasm could also be differentiated into cytoplasm and nucleoplasm based upon its location. Cytoplasm refers to protoplasm located outside the nucleus. Nucleoplasm refers to protoplasm located inside the nucleus. The two essential features of any living cell in the human body are that of presence of protoplasm and the nucleus.
The most striking characteristics of protoplasm are its vital properties of “Motion” and “Nutrition”. Protoplasm has the intrinsic power to change its shape and position. Motion of protoplasm is called ‘amoeboid movement’ as it resembles the movements observed in the Amoeba proteus animalcule. Nutrition is the power which protoplasm has of attracting itself the materials necessary for its growth and maintenance from surrounding matter and environment. The Egg Cell or the Ovum is the Source or the Mother of Life. This living matter, living substance, or corporeal material has divine attributes. It is conscious, it is aware, and it performs cognitive functions to sustain its own living condition.
Heredity is the sum of all biological processes by which particular characteristics are transmitted from parents to their offspring. A child inherits a genetic constitution from its biological parents. This hereditary endowment, the total of the genes that the child has received from both parents is called the genotype. The genotype of an individual is formed from the constituents of the genotypes of his parents. The genotype in a fertilized Egg Cell influences the developmental pattern of the child. Progeny is not exact duplicates of their parents and usually vary in many traits. Heredity and Variation are two sides of the same coin. The outward appearance of an organism is called the phenotype. The same individual shows different phenotypes in childhood, in adulthood, and in old age. The genotype, on the other hand, does not change during an individual’s life. Each cell in the human body contains the same total genetic information that was present in the fertilized Egg. However, the cells are not identical. In different types of cells, groups of genes are controlled (in effect switched on and off) by various biochemical processes, so that each cell manufactures the proteins and structures needed for it to function. Cells are regulated by the DNA in the nucleus and by the transfer of selected portions of the DNA information to the cytoplasm through the intermediate molecules of ‘Messenger RNA’. It is estimated that, on average, only about 10 percent of the genes of any cell are functional; selection of functional genes varies with the type of cell. This biological phenomenon of selective gene functioning may contribute to what I term as ‘The Law of Individuality’. Deoxyribonucleic acid or DNA accounts for the ability of all living matter to replicate itself exactly and to transmit genetic information from parent to offspring. The child maintains its individuality by selectively switching the inherited DNA on and off. The Law of Individuality applies to all living organisms. Despite the basic biological, chemical, and physical similarities found in all living things, diversity of life exists not only among and between species but also within every natural population.
The Mother Cell is the Source of Life for its child and yet the child comes into existence as a brand new and original product with its own Identity and Individuality. The Mother Cell does not manufacture the new multicellular organism called child. A child is always a created object even when it derives its life from a Mother Cell.
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance.The Divine Phenomenon – A child always comes into existence as a created object even when it derives its life from a Mother Cell.
Angel of Mercy, Grace, and Compassion – Mother – Source of Energy:
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance. The Divine Source of Energy.
To maintain life an organism not only repairs or replaces (or both) its structures by a constant supply of the materials of which it is composed but also keeps its life processes in operation by a steady supply of energy.
Living systems must be supplied energy for continual synthesis of new organic molecules and to replace or to repair broken organic molecules. This functional activity; the processes of synthesis and breakdown of organic molecules by a living cell, is known as metabolism. Metabolism involves a living system’s continual exchange of some of its materials with its surroundings, principally in the process of building up or destroying its protoplasm. growth involves a higher rate of synthesis of protoplasm than a rate of breakdown of that matter.
Organisms acquire energy for their metabolism by two general methods and could be classified as autotrophs or self feeders and heterotrophs or feeders of other organisms. Plants are known as Photoautotrophs as they acquire useful free energy from the energy of Sunlight. In a process known as Photosynthesis, plants use Sunlight to break water into Oxygen and Hydrogen. Hydrogen is then combined with Carbon dioxide to produce such energy-rich molecules as Adenosine triphosphate (ATP) and carbohydrates and the Oxygen is released back into the atmosphere. Humans and most other animals are known as heterotrophs – these organisms acquire energy by the controlled breakdown of pre-existing organic molecules (food) supplied by other organisms. Humans utilize the atmospheric Oxygen (released by plant life) to combine chemically with organic matter (food) they have eaten and release Carbon dioxide and water as waste products. Metabolic processes do not occur in one step. It is not similar to burning sugar in air.
The glucose, a simple sugar is broken down by a series of successive and coordinated steps, each mediated by a particular and specific enzyme. The human organism extracts useful energy by a metabolic process described as Oxidation-Reduction Reactions. The glucose is broken down in a series of about 71 enzymatically catalyzed steps. The first 11 of these biochemical reactions do not involve the use of Oxygen. These Oxidation-Reduction Reactions occur in intracellular organelles known as Mitochondria in the cytoplasm of cells.
Mitochondria – The Powerhouse of Cells:
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance.In Mitochondria, many substances are oxidized and ATP, the energy-storing chemical of the cell is produced. This energy is utilized in a variety of cellular functions and activities.
Mitochondria are typically sausage-shaped particles about 0.5 to one micron wide and about 5 to 10 microns long. They are surrounded by an outer unit membrane which controls the passage of material into and out of the mitochondria and govern their internal environment. The inner membrane is the site of the respiratory functions that make the mitochondria the so-called Powerhouse of the Cell. The inner membrane is folded repeatedly into shelf like folds called cristae which contain the enzymes that play an essential role in conversion of the energy of foodstuffs into the energy used for cellular activities.
Mitochondria and Chloroplasts – A Divine Source for Energy Acquisition:
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance. Both Mitochondria and the Chloroplasts are semi-independent and self-reproducing parts of the Living Cells. It is a Divine Mechanism to provide Energy for Metabolism the characteristic of Living Matter.Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance.The Mitochondria have a degree of “AUTONOMY” and they are unlike the other components of cells.
Mitochondria and Chloroplasts found in the green plant cells perform the same fundamental processes. The Chloroplasts contain the green colored pigment known as Chlorophyll. The Chloroplasts convert the energy of Sunlight into energy-rich ATP and use ATP to convert Carbon into specific organic substances. The most important equations for living things are mutually inverse. Respiration of human organisms represents the reverse of Photosynthesis of Green Plants. Both Mitochondria and the Chloroplasts are semi-independent and self-reproducing parts of the living cells. They have a degree of autonomy and they are unlike the other components of cells. Mitochondria contain DNA in the form of a Chromosome arranged in a ring. The DNA of Mitochondria has different distribution of bases from that of the DNA found in the Chromosomes present in the nucleus. Mitochondria carry the genes for their own replication and for the enzymes found in them. They can synthesize some of their own proteins and reproduce by themselves. In one respect the mitochondria function as the parts of the cells and in another respect, they behave like independent organisms that reproduce on their own.
The Mother Cell is the source of Mitochondria found in all the cells of my human body. During the Growth and Development of Human Embryo and Fetus, all the newly formed cells contain Mitochondria derived from the Egg Cell. Hence, mother as a biological parent represents the Source of Energy for all the Living Functions and activities of her children. I cannot move a muscle in my body without drawing energy supplied by the maternal Mitochondria which continue to live and replicate establishing my mother as the Source of Energy for my existence during my entire Life’s Journey.
Angel of Knowledge – Mother – Source of Knowledge:
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance. The Divine attribute of Motherhood is the Maternal Cytoplasmic Inheritance. Goddess Sarasvati is the Divine Mother of Knowledge. Indian Tradition recognizes Mind, and Intellect as aspects of Material Energies. Life functions with Knowledge implanted into Living Organisms which display the characteristics of awareness, responsiveness, alertness, and consciousness.
Life is the state of an individual characterized by the capacity to perform certain functional activities including the ability of responsiveness. Life is further characterized by presence of complex transformation of organic molecules and by organization of such molecules into the successively larger units of protoplasm, cells, organs, and tissues. Hence, I have defined Life as “Knowledge in Action.”
Responsiveness represents the ability of an organism to change in response to alteration in its environment. Responsiveness, alertness, awareness, and consciousness separates living from nonliving matter and defines life’s underlying principle. Living cells are aware or conscious of the environment in which they exist as well as the state of their own internal environment. The one very important part of environment of a cell is other cells. The ability called awareness and responsiveness is important for recognition, association, and cooperation between cells. Cells function together by exchanging chemical signals.
THE Cytoplasmic or Maternal Inheritance:
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic Inheritance. Mitochondria are inherited from maternal cytoplasm.
Deoxyribonucleic acid or DNA accounts for the ability of all living matter to replicate itself exactly and to transmit genetic information from parent to offspring. While offspring inherit a genetic constitution and hereditary traits from both parents, some characteristics are inherited through the maternal line only. For example, there are no Chlorophyll containing Chloroplasts in pollen grains of (male) flowers. The act of Pollination does not contribute this most important characteristic known as Chloroplasts. Chloroplasts are found only in the Egg Cells of (female) flowers. Similarly, humans inherit the Powerhouses called Mitochondria only from Maternal cytoplasm. A Cytoplasmic Inheritance is entirely Maternal. Human functions that involve Sensory Perception, Mental Cognition, Learning, and the functions of Memory and Consciousness should be viewed as functions of the cytoplasm. Cytoplasm represents the Seat of Knowledge. Man begins Life as a single cell with its cytoplasm. The cell grows and divides while building more of its cytoplasm. Knowledge is the Fact of Knowing, the State of Knowing, and the Act of Knowing a range of information. The Mother or the Source of Knowledge is the Maternal Cytoplasm inherited from the Egg Cell, Ovum, or the Mother Cell.
Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance.Happy Mother’s Day, Sunday, May 12, 2024. The celebration of maternal cytoplasmic inheritance
Mental Health – The Importance of Logical and Rational Thinking
Mental Health – The Importance of Logical and Rational Thinking
May is Mental Health Month, a time to shine a light on the importance of mental health to personal wellbeing and overcome reluctance to seeking help. Mental health is key to positive relationships and feelings of satisfaction and fulfillment in life. Mental health is also closely linked with physical health. Just as with physical health, mental health problems can be successfully treated.
Mental Health and the prevention of Suicide.
Mental Health America, the sponsor of Mental Health Month in the U.S., offers information and tools on its website: https://www.mhanational.org/mental-health-month. You’ll find helpful information on maintaining mental health and dealing with mental health issues on this website, too, including the following:
1 in 5 people will suffer from some form of mental illness in any given year. Break the Silence, Break the Stigma.
Mental Health and the prevention of Suicide
Man’s Physical Existence:
The subjective reality of man’s physical existence is conditioned by his physical, mental, social, moral, rational, and spiritual well-being.
If man is viewed as a multicellular human organism, we may have to ask ourselves the following question. Who or what is the subject who lives because of the functions of the trillions of cells? Man has to explore the biological basis for his existence in nature. The subjective reality of man’s physical existence is conditioned by his physical, mental, social, moral, rational, and spiritual well-being.
Mental Health – The Mind-Body Connection:
Mental Health and the prevention of Suicide
Mental health is an important component of the total positive health when health is defined as not the mere absence of disease, but as a state of man’s physical, mental, social, moral, rational, and spiritual well-being.
Mental Health and the prevention of Suicide
The man is conditioned to exist under the influence of a grand illusion such as the Sunrise and Sunset which regulates the biological rhythms. The man must find a rational basis for his physical existence as the realities of existing on the surface of a fast, spinning planet impose limitations on man’s cognitive abilities. In the final analysis, the man must face the challenges of living his mortal life finding solutions in a logical and rational manner. Physical conditions and ailments affect mental well-being. Mental health and well-being could have important consequences affecting the physical, and social well-being of the man and may even threaten his ability to maintain the biological integrity to survive as a human organism.
Mental Health and the prevention of Suicide
Mental health is defined as the capacity in an individual to form harmonious relations with others and to participate in or contribute constructively to changes in the social environment. A living organism has a tendency to maintain normal internal stability by coordinated responses that automatically compensate for environmental changes. Claude Bernard explained the concept of ‘milieu interieur’ as that of “all the vital mechanisms, varied as they are, have only one object; that of preserving constant the conditions of life.” This concept of homeostasis, the maintenance of stability and equilibrium is applicable to man’s existence within a social group. A living thing maintains its individuality while being a member of a social group. Mental equilibrium, and mental tranquility is needed to maintain internal stability and for developing harmonious relationships with others present in the social environment. The different constituent parts of one’s personality should work in harmony so that an individual faces life situations rationally, successfully, and happily. The aim of the positive mental health care is to strengthen and develop well-integrated personality by influencing the behavioral pattern of the individual so that psychological situations are controlled by the individual in a logical, and rational manner. The individual while facing challenging life situations must arrive at solutions without disrupting the physical, mental, or social well-being. Mental health comprises the well-being of the intellectual and the emotional components of the mind. The intellectual breakdown of the individual deprives him of logical and rational thinking. The decisions taken will be faulty if the individual is not capable of logical and rational thinking. Such faulty decisions tend to affect the individual’s well-being. Intellectual breakdown is always accompanied by emotional breakdown. Emotional imbalance affects individual’s reactions. The individual may show inability to cope with life situations. The inability to withstand the strain and stress of the life situations could affect the physical well-being of the individual. The aim of this presentation is to understand the nature of man’s essence and existence in the physical world and to use that information to prevent the problem of suicide.
Stress and Stress Resistance:
Mental Health and the prevention of Suicide. A person with a well-integrated personality acquires high resistance against stress and will be able to react healthily while confronting unwholesome life situations.
Resistance against mental and emotional breakdown is built up by the autonomic process of integration of personality. It is the normal process of the growth of personality within the group environs. An individual with a well-integrated personality acquires high resistance against difficult situations. The individual will be able to react healthily while confronting unwholesome life situations. A healthy mind and ability to be moulded in an integrated personality depends upon several factors including the physical, social, and psychological environment in which the individual is growing. It also depends upon the culture patterns and attitudes handed down from one generation to the next. From a very young age, integration of the personality proceeds along with intellectual development and emotional moulding. Children must be given a better chance to develop integrated personalities with resistance against stress. Stress stimuli generate a chain of psycho-physical reactions strong enough to cause manifest effects. Personalities can be divided into 5 types according to their ability to resist strain and stress to master a given difficult life situation without a physical or mental breakdown. The same psychogenic stimulus may not cause similar reaction in all individuals. Each person reacts in a different manner according to the level of preformed stress resistance.
Group I: Highly stress resistant. These persons have a high level of preformed resistance. They also have the ability to develop resistance within a short time when exposed to stress stimuli. This group comprises of people with well-integrated personalities with dominant will power and power of endurance. They carry out the task even while under great stress without experiencing any negative consequences. They successfully master the stressful and difficult situation. These individuals live in good positive health and may not have a preexisting disease condition or a predisposition to such disease conditions that may undermine the physical and mental aspects of their health and well-being.
Group II: These persons have an average amount of preformed stress resistance. They overcome the stressful situation partially. In the attempt to master the stressful situation and to achieve success the person may suffer from precipitation of internal conditions such as hypertension, coronary artery disease and so on when other predisposing factors are also existing. However, the individual completes the task while facing the stressful stimulus. These persons perform better if they maintain good positive health.
Group III: These are persons with very low preformed stress resistance. They still have the ability to develop resistance on exposure to a prolonged stressful situation. While performing the task under a stressful situation, they may display psycho-somatic symptoms of the overt stress syndrome.
Group IV: These are persons with no preformed stress resistance. They have a very low ability to create resistance upon exposure to a stressful stimulus. These individuals are more likely to abandon the task which may have exposed them to a stressful experience. They would try to escape from stress rather than attempting to create resistance to stress stimuli. If they cannot escape, the lack of stress resistance is manifested in a variety of bizarre symptoms.
Group V: These are persons who are non-resistant to stress. They have no preformed stress resistance. They are not capable of favorably reacting to stress producing situation. Their biological existence could be threatened if they are exposed to a stressful situation. They may manifest an overt psychiatric illness apart from the inability to perform a task that could generate the stress reaction. Such individuals must be recognized in their childhood and they must be provided proper environment and psychological counseling.
The part played by stress varies in different individuals according to their basic personalities. The factors that impact the role of stress include environmental influences, community with its varied backgrounds of culture patterns and life habits. Pre-existent resistance against stress reduces the requirement of immediate psycho-physical response. If the problem of suicide is viewed as a stress reaction, prevention of suicide would require promoting the idea of stress resistance.
The Problem of Suicide:
A man’s right to life is a well-recognized principle. Very often, the law would defend a man’s right to life and would condone the act of killing if it is purely intended for purposes of self-defense. Does a man have the right to kill himself or renounce his life? Suicide is condemned by various societies. Major religions like Judaism, Christianity, and Islam oppose the practice of suicide. Attempts to commit suicide are punishable by law in several countries. In the East, some cultural traditions have glorified acts of self-immolation or of renouncing life to resist enemy or to defend personal dignity, honor, or as an extreme measure of self-preservation.
Mental Health and the prevention of Suicide:To defend her true nature, to preserve her essence, to resist the violation of her personal dignity and honor, Rani Padmini of Chittorgarh, India had courageously responded to a difficult and challenging life situation by an act of self-immolation. Her physical being was destroyed by the fire which she had willingly embraced and yet her spirit has survived. She has declared Victory over Death and she lives as an immortal person in the hearts of Indians and gives them a sense of Pride and Identity. Indian Culture and Tradition glorify the act of giving life to resist the Enemy.
In the West, attitudes have been slowly changing. The law may permit euthanasia or physician-assisted suicide under very special circumstances that affect the quality of life of an individual.
The Problem of Suicide in the Armed Forces:
Mental Health and the prevention of Suicide. While serving as Medical Officer of the Indian Army Medical Corps, I provided Comprehensive Health Care to the troops and their families. The concept of Fitness to Fight includes both Physical Fitness and Mental Fitness. The goal is to keep the troops Fighting Fit at all times and under all conditions that may impose physical, psychological, social, or biological Stress. Indian Tradition has always paid attention to the well-being of all the aspects of health and it includes the Moral well-being, and the Spiritual well-being of the human being. During the years I had served, the incidence of Suicidal Death in the Indian Armed Forces was minimal.
To the members of the Armed Forces, the problem of suicide is of special significance. The Armed Forces as a military establishment has a very challenging and difficult duty to perform. It has to conserve man-power, keep up the morale of its troops, and retain its fighting abilities and capacities at all times, both during peace and during war. In ethical, and moral terms, Armed Forces believes in the act of killing and accepts the inevitability of causing deaths during the conduct of military operations. Armed Forces also actively prepares its members to overcome the fear of death and willingly exposes its members to the risks of getting killed both for the purposes of training and during actual combat situations. A soldier is not expected to kill himself to escape from the stress of his military duty and at the same time he must retain a very high level of motivation to kill the enemy and be willing to get killed in the performance of his task. Armed Forces selects its members with due care and chooses people with preformed stress resistance and further uses training as a tool to build up the stress resistance level of its members. The qualities of valor, duty, and honor define the essence and the spirit of service and Armed Forces members must exist to display their essence. I had participated in the military operations that were conducted in the Chittagong Hill Tracts during the Indo-Pak War of 1971 and I had encouraged men to overcome stress and had promoted the attitude of stress resistance. Kindly refer to my blog post titled ‘The Victory over Death – The Psychology of Warfare.
Suicide has become much more common and it ranks as the second or third most common cause of death during adolescence. Suicide is also most pronounced in the older age. The rate of suicide is greatest between the ages of 35 and 75 years with a peak at about the age of 55 years. According to the National Institute of Mental Health, in the year 2007, suicide was the third leading cause of death for young people ages 15 to 24. Among ages 65 and older, of every 100,000 people, 14.3 died by suicide in the year 2007. This figure is higher than the national average of 11.3 suicides per 100,000 people in the general population.
The Warning Signs of Suicide:
Suicide constitutes the greatest risk in manic-depressive psychosis . During depression, or mania, the psychotic individual shows no insight into the abnormal nature of his mood. Depression is a major symptom of neurosis. Attacks of depression are characterized by signs that the person has deep feelings of melancholia (sadness). The sufferer typically looks unhappy, he feels hopeless and worthless, considers his life a torment. The depressed individual may experience a desire to punish himself by self-destruction and may directly or indirectly express such feelings or thoughts.
The American Society for Suicide Prevention posted these warning signs of suicide, and signs of depression :- Unrelenting low mood, pessimism, hopelessness, desperation, anxiety, psychic pain, inner tension, withdrawal, sleep problems, increased alcohol or other drug use, recent impulsiveness & taking unnecessary risks, threatening suicide or expression of a strong desire or wish to die, making a plan, giving away prized possessions, sudden or impulsive purchase of a firearm, obtaining other means of killing oneself such as poisons or medications, unexpected rage or anger. Changes in attitude, personal behavior could be always discovered and the individual who is at the risk of taking his life could be helped by simple observation.
The Causes of Suicide:
Current research nad thinking on suicide tend to view biological, psychological, social-structural, and social-situational factors as interacting with each other. Sociological theories of suicide usually emphasize the importance of either the social structure or the social situations, and the cultural pressures that individuals face. Psychological theories emphasize personality and cognitive factors.
The Sociological Theory of Suicide:
Mental Health and the prevention of Suicide. Emile Durkheim (April 1858 to November 1917) is considered to be founder of the French School of Sociology.
Emile Durkheim in his paper ‘Le Suicide’ published in 1897, had tried to explain the apparent and purely individual decision to renounce life as a product of social forces or ‘social functionalism’. He had introduced the term ‘anomie’ or anomy. Suicide results from the breakdown of social standards that people need to regulate their behavior. A failed society produces in its members a sense of futility, lack of purpose, emotional emptiness, and despair. Anomie is a condition of relative normlessness of a society or social group. It may also mean a state of mind of a person who has no standards or sense of continuity or obligation to maintain his social bonds.
The Personality Theory of Suicide:
The desire to escape depression is the most frequently cited motivation to explain suicide. A personality factor could be involved in persons who believe that suicide constitutes a solution to the problems that they may be facing. The suicide victim’s ideas, beliefs, and ways of thinking have a causal relationship with an underlying personality. The way people view their problems can produce a greater or lesser tendency to depression and suicide.
The Quest for Authentic Existence:
Mental Health and the prevention of Suicide: Philosopher, Nobel Laureate Jean Paul Sartre recommended the quest for authentic existence. He claimed that Suicide is absurd; it is absurd to get rid of what man is (etre-en-soi) as the true subjectivity of man (etre-pour-soi) disappears at the same time.
The Existentialists suggest that a person must find a situation in which he finds his true significance. In his Existentialist book, ‘Being and Nothingness’, philosopher and Nobel laureate Jean Paul Sartre divides the being (the existing reality) into two categories. One category is called being-in-itself (etre-en-soi) and it may describe the essence of the man, the sum of the intrinsic properties without which a thing would cease to be what it is. The second category is being-for-itself (etre-pour-soi) which comprises the being that has thoughts, feelings, and consciousness. The being-for-itself exists only when it is supported by the being-in-itself. Existentialists view man in terms of his existing thoughts and actions rather than in terms of his essence. According to Sartre, man’s own existence is always attempting to overcome a radical estrangement between man as the object of scientific study or man himself (etre-en-soi) and the subjectivity man knows in his thoughts and consciousness (etre-pour-soi). A man’s life in the world and his social transactions often conceal his true subjectivity. A sense of authentic existence is given to each person when he realizes his true subjectivity as a being that is conscious. Sartre claimed that suicide is a final act of absurdity. Suicide is absurd; for in getting rid of what man is (etre-en-soi), the true subjectivity of man (etre-pour-soi) also disappears at the same time.
The Prevention of Suicide:
There is no single approach that could be expected to succeed in substantially reducing the incidence of suicide. However, it will not be incorrect to claim that suicide is 100 percent preventable. The act of killing oneself or the action called suicide is totally preventable even when suicidal thoughts may not be preventable. If an individual’s mind is engaged in suicidal thoughts, it may not be possible to prevent those thoughts as the thoughts have already originated. I may succeed in preventing the individual from acting upon his suicidal thoughts. As long as man knows his thoughts, and would not let his thoughts overwhelm him, man can lead a normal life even when the mind explores ideas or thoughts about suicide.
Stay Informed and Stay Connected:
Mental Health and the prevention of Suicide: Suicide is totally preventable if man seeks information about his essence and the connection that maintains his existence.
To help prevent suicide, I want to keep the man informed by sharing the following information, and the man must reflect upon the nature of the ‘connection’ that sustains man’s existence in the physical world.
Existence precedes Essence:
Existence is the state of being in the world of actuality. Essence is the most significant part of a thing’s nature, the sum of the intrinsic properties without which a thing would cease to be what it is. What is the fundamental nature or quality that is important or essential to define the true substance of the man? To understand human essence, a human being must be defined as a physical, mental, social, moral, and spiritual being. The subjective reality of man’s existence precedes and defines man’s essence. Existence is the first priority and must be preserved if man wants to define his nature or essence. To defend human existence, the physical, the mental, the social, the moral, and the spiritual well-being of man must be defended. As I have mentioned before, Indian tradition honors the man who may define his moral, or spiritual essence by putting an end to his physical existence. That is the only exception to the rule. The rule is; human existence does not depend upon the contents of man’s thoughts, feelings, desires, emotions, self-pride or ego. Man must always strive to rationally understand and evaluate his thoughts, feelings, desires, moods, emotions, and self-pride and should not act upon them to compromise his existence which is truly independent of such factors that impact human life. If I think that I must live for two hundred years, the thoughts about a long life span would not change the basis for my biological existence. Similarly, if I think that I must kill myself, the suicidal thought does not alter the basis for my biological existence. Suicidal thoughts do not describe human essence. A stress resistant individual would have the ability to investigate and reflect upon his suicidal thoughts and trace the reason for such thoughts. Stress is a problem that is associated with identity and individuality. The human person is a multicellular organism and man must know as to how the human organism establishes its identity and its individuality. While man seeks to define his essence in terms of his identity, the organism seeks to identify the individuality of the person whose existence the cells of his body tend to support.
Identity and Individuality – Two sides of the Same Coin:
Mental Health and the prevention of Suicide. If Essence describes one face of the coin, Existence describes the second face of the same coin.Mental Health and the prevention of suicide. If Identity is described by one side of the coin, Individuality is described by the second side of the same coin.
Mental health is related to the understanding of identity and individuality. We need to understand as to how identity and individuality is established in the multicellular human organism. My mind may define my identity in one manner and my human organism may establish my identity in a different manner. My mind may seek my identity from my thoughts, intellectual information & knowledge, emotions, and false ego. These four aspects of mental activities or functions are named in the Indian tradition as Manas, Buddhi, Chitta, and Ahamkara. These four mental activities are together named as Mano Chatushtayam or AntaHkaranam. Indian tradition asks people to recognize that the true identity of the individual does not pertain to these four aspects of human brain activities. The attempts by man to establish his identity on the basis of his morphological appearance, anthropometric data, biometrical information, race, ethnicity, gender, religion, language, or nation/ place of origin have no biological relevance in terms of supporting the existence of that human individual. Man exists as long as he has the ability to defend his individuality and maintains the integrity of the various physiological/metabolic activities that support the vital functions that impart the quality or condition called Life and keeps the organism living. In the human organism, this functional unity is maintained by an anatomical structure called Brain Stem. Man lives as an individual while the functions of the Brain Stem are intact and man dies if functional activity is not found in the Brain Stem. Man can seek any kind of identity if he could maintain the individuality that the Brain Stem supports. Man is free to change his morphological appearance, can change his sexual identity, can change occupation, speak a different language, change his place of residence, practice a different religion or no religion, and can change the nature of his personal relationships with others while he maintains his individuality as a living organism. A man must be always conscious of his individuality which exists as a distinct entity from his mind and its mental activities. A man could be aware of the presence of suicidal thoughts engaged by his mind and yet maintain his separation from those thoughts. A man who seeks to exist as an individual will have no problem in resisting his thoughts, feelings, emotions, and mood changes. Such mental activities would not overwhelm or overpower the person. The problem of stress would not go away. However, man can become stress resistant. Such stress resistance from psychogenic stimuli is the key for prevention of suicide. The man who is facing challenging life situations represents just one side of the coin, and on the second side is represented the man who is maintains his individuality as a human organism. This separation of identity from individuality gives us the scope to make people stress resistant and to avoid the psychological compulsions of suicidal thoughts. When this separation is established, a man would not act in ways that could harm him in body or mind. To promote mental health, to prevent the consequences of mental disease, we need to give the tools to people to understand and define individuality and identity as two separate aspects of the same coin.
The ‘Self’ and the ‘Knowing-Self’:
Mental Health and the prevention of Suicide.Man could be divided into two categories; the ‘SELF’ represents man as the physical, mental, and social being; the ‘Knowing-Self’ represents man as the Moral and Spiritual being. The ‘Knowing-Self’ could be described as the function of the Reticular Formation of the Brain Stem.
I divide the living human being into two categories. The first category called ‘Self’ may be compared to Sartre’s Being-in-itself or etre-en-soi. The category ‘Self’ represents man’s state of existence as the physical, mental, and social being. Both Rene Descartes and Jean Paul Sartre divide man into two categories; 1. a physical or inert substance that has no thoughts, feelings, or consciousness, and 2. the mind that has thoughts, feelings, and is a conscious entity. Sartre had further named the second as the Being-for-itself or etre-pour-soi which is capable of making decisions and giving man the freedom to act according to his freewill. I do not subscribe to the views held by Descartes or Sartre and I would not seek separation of mind and body into two distinct categories. Man is a multicellular organism; the body cannot exist without a mind/brain and the mind/brain cannot exist without a body which has vital organs like lungs, heart, liver, and kidneys. The body and the mind/brain have to function together. I have also stated my view about consciousness. Please visit the page titled, “I am Consciousness, Therefore I am”
Consciousness is not an exclusive psychological function. Consciousness is a biological function that is shared by all living cells which display the attributes such as recognition, sensitiveness, coordination, cooperation, functional awareness, and awareness of external and internal environment and condition. The category that I call ‘Self’ represents the physical self with various organs and tissues and the mental self which represents mental activities associated with thinking, intellect/knowledge, emotions, feelings, moods, and ego or self-pride. The ‘Self’ may describe the essence or nature, or identity of the man in terms of the man’s own mental awareness and other people in his environment. The second category that I describe could be called the ‘Knowing-Self’. The ‘Knowing-Self’ is aware or conscious of its state and fact of biological existence. It may not always be aware of its external environment. A man who is in a state of sound sleep, a man who is under the influence of drugs, chemicals, or pharmacological agents like anesthetics, or a person with a head injury loses some components of the function called consciousness. However, a man at all times of his living condition is conscious of his internal condition/environment, maintains the state of equilibrium or homeostasis, and supports the vital functions that define his individuality as an organism. The category called the ‘Knowing-Self’ is related to the individuality and in the multicellular human organism this function is served by the Reticular Formation of the Brain Stem which gives the person the ‘Capacity for Consciousness’. Man needs the ‘Capacity for Consciousness’ to compose the ‘Contents of Consciousness’. In the absence of the ‘Capacity for Consciousness’, man has no ‘Contents of Consciousness’ and could be declared dead if the function called ‘Capacity for Consciousness’ could not be sustained. The ‘Capacity for Consciousness’ is essential for man’s biological existence. The ‘Capacity for Consciousness’ is required for man to exist as a moral and spiritual being. Man exists with an intrinsic ability to discern right from wrong, and exists because of his spiritual nature which gives him the ability to acquire energy for his various metabolic, living functions. The category called ‘Self’ may experience all the difficult, and challenging situations posed by life, and the category called the ‘Knowing-Self’ is not subject to these sensory or mental experiences that impact the ‘Self’.
The God Connection – Stay Connected:
Mental Health – The Importance of Logical and Rational Thinking
Man must recognize that his biological existence depends upon energy acquisition. Man leads energy-dependent existence and must acquire energy from external sources right from the beginning of his life journey, from the moment of conception. Man does not acquire this energy because of his intellectual effort, or acquired knowledge. The ‘egg cell’ that is fertilized is conscious of its energy dependence and it implants itself into the tissues of the mother who may not be mentally aware of this process called implantation by which the human embryo starts deriving its energy from its mother. This embryo grows and develops into a complex, multicellular organism and continues to derive energy from external sources. This ‘Connection’ between the energy-seeker, and the energy-provider could be called ‘God Connection’. Man has no ability to establish this kind of energy acquisition for his survival. If Sun is viewed as the source of extraterrestrial or Cosmic Power, the Solar Energy is trapped by chloroplasts found in the cells of all green plants. This energy is further made available to man by the presence of intracellular organelles called mitochondria which are described as the powerhouses of the cells. Man has no direct control on the nature of this ‘Connection’ and its operation. Man simply exists as there is a Provider for his energy requirements. In good health, or ill-health, under all circumstances and conditions, and during all the stages of his mortal existence, man needs this grace, mercy, and compassion to keep himself alive. This is a supernatural mechanism, or a ‘God Connection’ that supports man while he leads his energy dependent existence. Man who experiences this compassion, mercy, and grace that is sustaining his life would derive a sense of joy and experiences the condition called true happiness. A man who has discovered true happiness cannot experience a mood called depression. It is really hard to kill oneself while the man is connected to a source of Happiness. Man must experience this sense of Joy and Happiness and realize its uplifting power to alter any depressed feeling or mood. If pain is an inevitable aspect of human life, compassion is also an inescapable aspect of human existence. If pain is true, compassion is also equally true. I invite people to find Compassion, Mercy, and the Grace of the Divine Providence in their lives. It would be irrational or absurd to break the God Connection by the act called Suicide.
Dr. R. Rudra Narasimham, B.Sc., M.B.B.S.,
Kurnool Medical College, Kurnool, Andhra Pradesh, India,
M.B.B.S., Class of April, 1970.
Mental Health and the prevention of Suicide: BODY-MIND-SOUL ARE CONNECTED TO EACH OTHER, WITH SOUL HAVING A CENTRAL CONTROLLING POWER OVER SOME ASPECTS OF FUNCTIONS OF OTHER PARTS OR UNITS TO PROMOTE UNITY AND HARMONY.
Whole Dude – Whole Coming: The Birth of Jesus is the First Singular Event; the Resurrection of Jesus and His Ascension constitutes the Second Singular Event and the Third Coming or the Future Coming, or the Final Coming constitutes the Whole Coming of Jesus for it includes a Plan for a New Heaven and Earth.
Sixth-Day Adventism describes the Whole Law that governs the Whole Existence
June is Professional Wellness Week – The benefits of Sixth-Day Adventist Positive Work Culture. This article is dedicated to the loving memory of Jessica Cole of Seventh-Day Adventist Church, Bangalore (Bengaluru), India.
This article is dedicated to the loving memory of Jessica Cole, my relative who lived in Bangalore (Bengaluru), India as a member of the Seventh-Day Adventist Church. She inspired me to formulate the Sixth-Day Adventism concepts of Whole Christ, Whole Love, Whole Gospel and Sixth-Day Adventist Positive Work Culture.
Whole Christ – Whole Love – Whole Gospel:
WHOLE CHRIST – WHOLE LOVE: The term “Whole Christ” refers to Jesus before His human birth, during His earthly existence, after His Resurrection, and to the Hope of His Advent or Coming to establish the ‘Kingdom of Heaven on Earth’.The term “Whole Love” describes God’s Unconditioned Love that is not determined by human knowledge and rationality. The Birth of Jesus cannot be fully accounted by human knowledge and rationality for man lacks the ability to account for his own existence.
The word Christ (Greek. Christos) refers to the Messiah whose appearance is prophesied in the Old Testament and is used as a title to describe Jesus of Nazareth. I am using the term “Whole Christ” to describe Jesus before His human birth, Jesus during the years spent on this Earth, Jesus after His Resurrection, and Jesus who gives the Hope of Advent or the Coming to establish The Kingdom of Heaven on Earth. The word Christ may not communicate the entirety of Jesus and in the four Gospels we do not obtain the full picture as the event called ‘The Advent or Coming’ has not yet taken place. The word “Love” (Hebrew. ‘ahavah’, Greek. ‘agape’) is presented in Scripture as the very nature or essence of God, the supreme attribute in which all other attributes are harmonized. Love is a bond that unites all virtues. I consider the Power/Force/Energy of Mercy, Grace, and Compassion as the operating mechanism of God’s Love and could be simply called Divine Providence. I am using the term “Whole Love” to describe God’s Unconditioned Love that is not determined or fully accounted by human knowledge and human rationality. In other words, I have no ability to empower myself to receive God’s Unconditioned Love. I cannot manipulate God’s Whole Love through my actions, behavior, or even prayers. I can experience Whole Love but, I cannot explain or fully account for the existence of that Love.
Whole Christ – Whole Love – Whole Creation:
Whole Christ – Whole Love – Whole Creation: The Birth of Jesus as a Spiritual Being cannot be fully accounted by using human knowledge and human rationality. Man must try to know and understand as to where he exists and as to how he exists. God uses the dimension called Whole Love to bring Unity and Harmony between the dimensions of Matter, Energy, Time, and Space to create man and the World in which man exists.
Man cannot explain the Birth of Jesus using his scientific knowledge. The Birth of Jesus can only be understood as a fact of Creation, a creative event. It should not come as a surprise as each human being who took birth on Earth has always arrived as an original, unique, distinctive, and one of its own kind of object with a genome that never existed in the past, and would also never exist again in the future. Each man is born as a created being and the birth of Jesus as a singular event reveals a creative mechanism not known to man and not subject to the limitations of man’s rational power. God uses the dimension called Whole Love to bring Unity and Harmony between the dimensions of Matter, Energy, Time, and Space to create man and the World in which man exists.
Whole Christ – Whole Love – Whole Existence:
Whole Christ – Whole Love -Whole Existence: The Birth of Jesus and His earthly existence describes the operation of a Supreme, Spiritual WholeLaw that harmonizes all Laws of Nature that operate in the physical world to establish WholeExistence which may be stated as a Law of Conservation:” Matter is neither created nor destroyed.” Similarly, it can be stated: “Life is neither created nor destroyed.”
Whole Christ – Whole Love – Whole Existence: God Exists. Very often people raise the question about God’s place of existence in this vast universe of unknown dimensions. Where does man exist? How could man be certain about the location of his own existence in this universe which is constantly moving every instant?
Whole Christ – Whole Love – Whole Existence: Where does man exist? It is easy to describe man’s place of existence in the Solar System, and Milky Way Galaxy, but in reality man exists in Space without any awareness of his position that is changing every instant. No object that is known in this universe continues to exist at the same position at two different instants. Man exists in a restless universe under the Blissful influence called WholeLove which shields man from the harsh realities of physical universe.
To experience the Joy of Christmas, to seek the uplifting power of Jesus Christ, man must know the truth and reality about human existence. Human knowledge and rationality in themselves do nothing to justify human existence or the existence of this universe. To establish the fact of this human existence on one known planet called Earth is beyond the abilities of human cognitive powers. The biological basis of human existence demands the support of Love whose operating principles are Mercy, Grace, and Compassion. This Love is not conditioned by human behavior and human actions and not even prayers. Man cannot empower himself to acquire God’s Love using his free will. The good and evil actions of man, the right and bad conduct of man will be possible if and only if man’s existence precedes his actions and behavior. It is often argued that the evil and suffering in the world seems to count against the existence of God. I have to account for my physical existence before I can share the experience of pain, misery, disappointment, frustration, and suffering of my life’s condition. The fact or the reality of human pain and suffering cannot exclude the fact of God’s existence. Man at any given age and any given stage of his existence, from conception, physical birth, infancy, youth, adult, old age and death, in ill-health or good health depends upon an Unchanging Spiritual Principle to bring Unity and Harmony to maintain that condition or state called existence. This concept of God’s Unconditioned Love or WholeLove for man is shared by the Birth of Jesus. When I think of this WholeLove, I feel better, my mood gets uplifted, the burden of my painful existence is eased, and I can sense the Joy of the Season.
Whole Christ – Whole Love – Whole Law:
Whole Christ – Whole Love – Whole Law: Love is defined by stating its attributes. Love is Patient. Love is Kind. Love does not envy. Love does not boast, it is not proud. Love is not rude. Love is not self-seeking. Love is not easily angered. Love protects, trusts, hopes, always perseveres and Love never fails. Divine Mother Mary is seen expressing such Love for her baby Jesus.
Apostle Paul in his First Epistle to Corinthians, in the New Testament Book of 1 Corinthians, Chapter 13, verses 4 to 8 describes the attributes of Love: “Love is patient, love is kind. It does not envy. It does not boast, it is not proud. It is not rude, it is not self-seeking, it is not easily angered, it keeps no record of wrongs. Love does not delight in evil but rejoices with the truth. It always protects, always trusts, always hopes, always perseveres. Love never fails. But where there are prophecies, they will cease; where there are tongues, they will be stilled; where there is knowledge, it will pass away.”
Whole Christ – Whole Love – Whole Law
Jesus Christ while teaching the operating principle called Love, names Love as a Law, a Law above all other laws of nature, and above all other Commandments. In the Gospel According to Saint Matthew, Chapter 22, verses 37 to 40 “WholeLove” is explained as “Whole Law”: Jesus replied: ” ‘Love the Lord your God with all your heart and with all your soul and with all your mind.’ This is the first and greatest commandment. And the second is like it: ‘Love your neighbor as yourself.’ All the Law and the Prophets hang on these two commandments.”
Whole Christ – Whole Love – Whole Law
Love is the supreme attribute, nature, and essence of God and at the same time it operates as a Law above all other Laws of Nature and the commandments shared by Prophets. WholeLove can be stated as the WholeLaw that governs the existence of man and gives man the chance to experience Peace, Harmony, and Tranquility in his living condition.
Whole Dude – Whole Coming: The Birth of Jesus is the First Singular Event; the Resurrection of Jesus and His Ascension constitutes the Second Singular Event and the Third Coming or the Future Coming, or the Final Coming constitutes the Whole Coming of Jesus for it includes a Plan for a New Heaven and Earth.
Whole Christ – Whole Love – Whole Reality:
The term WholeChrist describes Jesus as an eternal, immortal, unborn Spiritual Principle that existed before His birth, that existed in the Middle or during His earthly Life, and continues to exist in Future without being influenced by Time.
Whole Christ – Whole Love – Whole Reality: The Birth of Jesus Christ. Life is neither created nor destroyed. The term WholeChrist describes Jesus as an eternal, immortal, unborn Spiritual Principle that existed before His birth, that existed in the Middle or during His earthly Life, and continues to exist in Future without being influenced by Time.
Apostle Paul in his First Epistle to Corinthians, 1 Corinthians, Chapter 13, verse 13 shares the Spiritual Principles of Conservation: “And now these three remain: faith, hope, and love. But the greatest of these is love.”
Whole Christ – Whole Love – Whole Reality: The Spiritual Principles of Conservation
Man exists in a world that is restless and is constantly changing. The Individual, created human being is born, grows and develops, exists with a physical identity that constantly changes under the powerful influence of Time and the event called death records the loss of that identity that is never constant at any time of its earthly existence. In the natural world, such changes in appearance are governed by the Laws of Conservation such as the Laws of Conservation of Mass, Energy, and Momentum. During man’s physical existence, the physical form and appearance change and yet the Spiritual Principles of Faith, Hope, and Love are conserved. Man cannot depend upon his knowledge and rationality as they are always subject to change. To know the Subjective and Objective Reality or the “WholeReality” of his ‘WholeExistence’, man needs to know the Law of Conservation of Faith, Hope, and Love.
Whole Christ – Whole Love – Whole Prayer:
Whole Christ – Whole Love – Whole Prayer: The Gospel According to Saint Matthew, Chapter 6 gives the account of “Whole Prayer” that is popularly known as ‘Lord’s Prayer’. Father knows what you need before you ask Him. We pray for His “WILL” be done on earth as it is in Heaven. The ‘Whole Prayer’ gives virtues such as Patience, Perseverance, Tolerance, and Kindness the attributes of ‘Whole Love’.
The word Prayer refers to man’s communication with God. It is a spiritual or devotional communication to make a humble, sincere request. Prayer is the act of supplication and it includes words of praise, words of thanksgiving, words of confession, and words of plea seeking sanction of a favor to transform a mental desire into a physical reality in the external world. If God is omniscient, He must know of the evil; and if God is omnipotent, He must be able to remove the evil; and if God is perfectly benevolent and is loving, there should be no pain and suffering. To experience pain and misery, to experience suffering, disappointment and frustration, I have to maintain the condition called existence. At a fundamental level, I have to understand my ability to know things, my power to rule or govern things, and I must know my ability to make choices to change things in my external environment.
Whole Christ – Whole Love – Whole Prayer
Jesus in the New Testament Book of Matthew, Chapter 6, verse 8 instructs: “Do not be like them (pagans), for your Father knows what you need before you ask Him.” In Lord’s Prayer, Jesus makes it abundantly clear that the purpose of the ‘Whole Prayer’ is that of asking, “Your will be done on earth as it is in heaven.” Using my human knowledge and rationality, I can neither account for my existence nor account for my experience of pain and suffering which describes the nature of my existence.
I describe ‘Whole Prayer’ as an act of Faith, and Hope in recognition of the fact or reality called Whole Love that imparts its qualities and virtues such as Patience, Perseverance, Tolerance, and Kindness. Even if I cannot change the circumstances of my life that cause or give the experience of pain, suffering, and misery, the acceptance of Whole Love makes me pain-tolerant, and pain-resistant. It gives me the strength called ‘Endurance’ to overcome the challenge called the ‘Stress of Life’.
Whole Christ – Whole Love – Nietzsche: “That which is done out of Love always takes place beyond Good and Evil.” Man with his Good or Evil actions and behavior cannot control the flow of God’s Unconditioned or ‘Whole Love’.Whole Dude – Whole Coming: The Birth of Jesus is the First Singular Event; the Resurrection of Jesus and His Ascension constitutes the Second Singular Event and the Advent, the Coming or the Future Coming, or the Final Coming constitutes the Whole Coming of Jesus for it includes a Plan for a New Heaven and Earth.
Whole Christ – Whole Love: The Advent or the Coming of Christ is of very special interest to man as it reveals God’s costly plan for man’s redemption through Jesus Christ.
The Process of Whole Nourishment Provides Nourishment to Body, Mind, and Soul
Whole Dude – Whole Foods – Whole Nourishment – Whole Spirituality: Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods.
What is Nourishment?
Whole Dude – Whole Nourishment: The Process of Whole Nourishment involves three fundamental principles, 1. Food, 2. The Consumer of Food, and 3. The Provider of Food.
To define food as any substance consumed to provide the nutritional support to an organism is incomplete as it fails to describe the totality of the relationship between food and its consumer. The term Food cannot be defined without defining the Organism, the Consumer of Food. I describe the Seven Dimensions of the man. These are, 1. The Physical, 2. The Mental, 3. The Social, 4. The Moral, 5. The Spiritual, 6. The Creative, and 7. The Rational. I define Whole Food as substances consumed by the man to provide support to the Seven Dimensions of the man. Hence, Whole Food is defined as the Spectrum of Seven Colors. The concept of Whole Nourishment describes the process of providing Nutrients that brings Unity of Body, Mind, and Soul.
Whole Dude – Whole Nourishment: The Spiritual Medium to Provide Nourishment to Life. I am using the term Spiritual Medium to describe Protoplasm for I want my readers to understand the importance of Culture Medium to provide Support to Living Organisms.Whole Dude – Whole Nourishment: The Spiritual Medium to Provide Nourishment to Life. I am using the term Spiritual Medium to describe Protoplasm for I want my readers to understand the importance of Culture Medium to provide Support to Living Organisms.Whole Dude – Whole Foods – Whole Nourishment: Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods.
What it is to be a Substance? and What it is to Exist? We need to establish knowledge about the man and the world on a firm basis and the information it provides must be tested for its accuracy and consistency with an external reality.
Whole Dude – Whole Foods – Whole Nourishment: Goddess Annapurna is depicted as The Mother Principle of human creation and existence. The celebration of Whole Food as a Spiritual Substance of Human Nourishment. Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods
At Whole Foods, I discovered the spiritual connection between man, food, and Providence. Whole Foods, Whole People, and Whole Planet are connected by a material substance called Protoplasm, a divine plan to provide nourishment to Life.
Whole Dude – Whole Nourishment: Whole Dude Loves Whole Food he purchases at the Whole Foods Market, Ann Arbor, Michigan, USA. Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods.
I coined the phrase Whole Spirituality to describe the three dimensional spiritual relationship between the multicellular human organism, food, and the Divine Providence.
Whole Dude – Whole Nourishment: The spiritual connection between Cell and its Energy Provider. The 3-Dimensional Spiritual Relationship between Man, Food, and God.
Spiritualism – The Cell Theory of Spirituality:
Whole Dude – Whole Nourishment: The Discovery of the concept of Whole Spirituality, the three dimensional spiritual relationship between the multicellular human organism, food, and the Divine Providence.
In Biology, cell is the basic or fundamental unit of structure, function, and organization in all living things or it is the building block of life. Let me begin with my respectful tribute to some of the people who contributed to ‘The Cell Theory’, one of the foundations of Biological Sciences. Cells were first observed in the 17th century shortly after the discovery of the microscope. Robert Hooke, british curator of instruments at The Royal Society of London, during 1665 coined the word cell. Dutch microscopist Antonie Van Leeuwenhoek (1632-1723) made over 247 microscopes and examined microorganisms and tissue samples. He gave the first complete descriptions of bacteria, protozoa (which he called animalcules), spermatozoa, and striped muscle. He also studied capillary circulation and observed Red Blood Cells.
Whole Dude – Whole Nourishment: The Spiritual Medium to Provide Nourishment to Life: Robert Hooke, British curator of instruments at The Royal Society of London coined the term cell during 1665.Whole Dude – Whole Nourishment: The Spiritual Medium to Provide Nourishment to Life: Dutch microscopist Antonie Van Leeuwenhoek (1668-80) studied capillary circulation and observed Red Blood Cells.
Improvements in microscopy during early 19th century permitted closer observation and the significance of cells had received better understanding. Matthias Jakob Schleiden (1838), German botanist, Theodor Schwann (1839), German physiologist, and Rudolf Virchow (1855), German pathologist, and others made important contributions to the Cell Theory that describes cell as the building block of all Life.
Whole Dude – Whole Nourishment: The Spiritual Medium to Provide Nourishment to Life: Schleiden, Professor of Botany, The University of Jena studied plant structure under the microscope, published “Contributions to Phytogenesis”(1838). He had also published the two-volume text of ‘Principles of Scientific Botany’.Whole Dude – Whole Nourishment: The Spiritual Medium to Provide Nourishment to Life: Schwann founder of modern Histology extended the Cell Theory of Plants to animals in his ‘Microscopic Researches into Accordance in the Structure and Growth of Animals and Plants(1839).Whole Dude – Whole Nourishment:The Spiritual Medium to Provide Nourishment to Life: Schwann discovered Myelin Sheath covering peripheral axons, now termed Schwann Cells. He coined the term ‘Metabolism’ for the chemical changes that take place in living tissues.Whole Dude – Whole Nourishment: The Spiritual Medium to Provide Nourishment to Life: Rudolf Virchow, German pathologist in 1855 coined the biological dictum “OMNIS CELLULA E CELLULA” – All living cells arise only from pre-existing living cells.
The Cell is the smallest unit in the living organism that is capable of carrying on the essential life processes of sustaining metabolism for producing energy and reproducing. Many simple, small, single-celled organisms like Protozoa perform all life functions. In higher, complex, bigger, multicellular organisms, groups of cells are structurally and functionally differentiated into specialized tissues, organs, and organ systems. Thus, the Cell Theory includes the following foundational principles of the Biological Sciences:
1. All living things are made up of cells. Cell is the most elementary or basic unit of Life.
2. Cell is a fundamental unit of structure, function, and organization in all living things including plants and animals.
3. Cells only rise from division of previously existing cells.
4. All cells are similar in composition, form, and function. All cells are basically the same in chemical composition (in spite of variations) in organisms of similar species. For example, all the solid tissues in the human body can be shown to consist largely of similar cells; differing it is true, but that are essentially similar to an Ovum.
5. The cells exhibit functional autonomy. The activity of an organism depends on the total activity of ‘INDEPENDENT’ cells.
6. Energy flow (metabolism and biochemistry) occurs within cells.
7. Cells contain hereditary, biological information (DNA) which is passed from cell to cell during cell division.
The Cell Theory of Spirituality:
Whole Dude – Whole Nourishment: The Discovery of the concept of Whole Spirituality, the three dimensional spiritual relationship between the multicellular human organism, food, and the Divine Providence.
The basic or fundamental unit of life in the human organism is derived from the fertilized egg cell that eventually develops into a complete organism. The most significant feature of similarity between the cells of the human body is the presence of a soft, gelatinous, semi-fluid, granular material inside the cell. This substance known as Protoplasm or Cytoplasm, or Cytosol is similar to the ground substance found in the Ovum or the Egg Cell.
The Spiritual Medium to Provide Nourishment to Life: Life begins at Conception. Human Ovum Structure – The Cell Theory of Spirituality is based upon the Substance, Structure, Form, Organization, Function, Action and Interactions of this Single Fertilized Egg Cell that eventually develops into a complete human organism.
Protoplasm, the viscous, translucent, colloidal substance is enclosed in a membrane called Cell Membrane, Plasma Membrane or Biological Membrane. A small spherical body called nucleus is embedded in the Protoplasm of the cell. The three essential features of any living cell in the human body are that of the presence of protoplasm, the nucleus, and the cell membrane.
Protoplasm – The Ground Substance of Spiritualism and Spirituality:
Whole Dude – Whole Nourishment:The Spiritual Medium to Provide Nourishment to Life: The Discovery of the concept of Whole Spirituality, the three dimensional spiritual relationship between the multicellular human organism, food, and the Divine Providence.
I seek the existence of Soul or Spirit in a substance that is basic to life activities, and in a material that is responsible for all living processes. I, therefore, propose that the understanding of the true or real nature of this ground substance of all living matter will help man to discover peace, harmony, and tranquility in all of his internal and external relationships while man exists in a physical environment as a member of a social group, social community, and Society. In this blog post, I would like to pay my respectful tribute to Jan Evangelista Purkinje and Hugo Von Mohl for their great contribution to the scientific understanding of the living substance, living material, and living matter.
Whole Dude – Whole Nourishment: The Spiritual Medium for Providing Nourishment to Life: Jan Evangelista Purkyne (Czech name), Jan Evangelista Purkinje (German name)also known as Johannes Evangelist Purkinje, b. December 17, 1787, d. July 28, 1869. The pioneer Czech experimental Physiologist whose investigations in the fields of Histology, Embryology,and Pharmacology helped create a modern understanding of the eye and vision, brain and heart function, mammalian reproduction, and the composition of cells.
Purkinje conducted his research on human vision at the University of Prague and later on, he served there as a Professor of Physiology (1850-69). He went to Germany and was appointed the Chair of Physiology and Pathology (1823-50) at the University of Breslau, Prussia. There Purkinje created the world’s first independent Department of Physiology (1839) and the first Physiological Laboratory (Physiological Institute, 1842). He is best known for his discovery of large nerve cells with many branching extensions found in the cortex of Cerebellum of the brain (Purkinje Cells, 1837). He discovered the fibrous tissue that conducts electrical impulses from the ‘pacemaker’ called Atrioventricular node or A-V node along the inside walls of the ventricles to all parts of the heart to help in Cardiac contractile function (Purkinje Fibers, 1839). In 1835, he invented and introduced the scientific term ‘Protoplasm’ to describe the ground substance found inside young animal embryo cells. He discovered the sweat glands of the skin (1833); he discovered the nine configuration groups of Fingerprints used in biometric identification of man (1823); he described the germinal vesicle or nucleus of the unripe ovum that now bears his name (1825), and he noted the protein digesting power of pancreatic extracts (1836).
Whole Dude – Whole Nourishment: The Spiritual Medium to Provide Nourishment to Life: Hugo Von Mohl, b. April 08, 1805, d. April 01, 1872, German Botanist noted for his research on the anatomy and physiology of plant cells.
Hugo Von Mohl named the granular, colloidal material that made up the main substance of the plant cell as “Protoplasm” in 1846. Purkinje invented the word, but Hugo gave more clarity, understanding, and knowing the nature of this ground substance.
Whole Dude – Whole Nourishment: The Spiritual Medium for Providing Nourishment to Life: Protoplasm or Cytoplasm is the clear, soft, gelatinous living substance found inside all living cells. A most striking characteristic of Protoplasm is its vital property of Nutrition. Nutrition is the power which Protoplasm has of attracting to itself the materials that provide energy and are necessary for its growth and maintenance.
Hugo Von Mohl viewed cell as an “elementary organ” and in Physiology he explained Protoplasm as an organ of Motion or Movement, Nutrition, and Reproduction. It is the preliminary material in cellular generation. He was the first to propose that new cells are formed by division of preexisting cells and he had observed this process of Cell Division in the algal cells of Conferva glomerata. His observations are very important to understand the Cell Theory that explains cells as the basic building blocks of Life. He was the first to investigate the phenomenon of the stomatal openings in leaves.
Whole Dude – Whole Nourishment: The Spiritual Medium to Provide Nourishment to Life:Protoplasm or Cytoplasm is the clear, soft, gelatinous living substance found inside all living cells. A most striking characteristic of Protoplasm is its vital property of Nutrition. Nutrition is the power which Protoplasm has of attracting to itself the materials that provide energy and are necessary for its growth and maintenance.
Protoplasm is a complex, viscous, translucent solution of such materials as salts and simple sugars with other molecules, mostly proteins and fats, in a colloidal state, that is dispersed but not dissolved in one another. Carbon, Hydrogen, Oxygen, and Nitrogen constitute more than 90 percent of Protoplasm. It exhibits properties such as Protoplasmic Streaming or Cytoplasmic Streaming or Motion that is called “Amoeboid Movement.” It has the intrinsic power to change its shape and position. It has the power of Nutrition by which it can attract and obtain the materials necessary for its growth and maintenance from surrounding matter/environment. These functions involve acquiring, processing, retaining, and using information to perform tasks in a sequential manner for a predetermined purpose and hence describe Consciousness, Memory, and Intelligence. The terms Soul and Spirit belong to the materialistic realm where the Physical Reality of man’s biological existence is established. I have not yet discovered any good reason to use the terms Soul and Spirit as a metaphysical or transcendental Reality.
The Ground Substance of Spiritualism and Spirituality:
Whole Dude – Whole Nourishment: The Ground Substance of Spiritualism and Spirituality. The vital characteristics, the animating principles of Protoplasm could be known by observing Amoeba proteus. The Living Substance works as an organ of Motion or Movement, as an organ of Nutrition, and as an organ of Reproduction to generate new cells which have a life span of their own. In these physiological functions, I describe the characteristics such as Cognition, Consciousness, Memory, and Intelligence which have a Spiritual role as they bring functional unity and harmony in the interactions between different parts of the same individual organism while it exists in an environment as a member of a biological community.
The vital characteristics, the animating principles of Protoplasm could be known by observing Amoeba proteus. The Living Substance works as an organ of Motion or Movement, as an organ of Nutrition, and as an organ of Reproduction to generate new cells which have a life span of their own. In these physiological functions, I describe the characteristics such as Cognition, Consciousness, Memory, and Intelligence as spiritual attributes of Life as they bring functional unity and harmony in the interactions between different parts of the same individual organism while it exists in an environment as a member of a biological community.
The Spirituality of Substance, Function, Organization, Action, and Interactions:
Whole Dude – Whole Nourishment: The Discovery of the concept of Whole Spirituality, the three dimensional spiritual relationship between the multicellular human organism, food, and the Divine Providence.
To establish the biological existence of the human organism, I add the concept of Spiritualism and Spirituality to the Cell Theory. The Single Fertilized Egg Cell has ground substance that is of Spiritual nature and the Spiritualism and Spirituality consists of the following functional, and organizational characteristics:
1. The Cell is Conscious of its own existence and knows its internal condition and knows it external environment.
2. The Cell is intelligent and it has the cognitive abilities like perception and memory to acquire information, to retain information, to recall information, and to use information in the performance of its complex tasks in a sequential manner.
3. The Cell has the ability to show characteristics such as mutual cooperation, mutual tolerance, and display functional subordination and subservience while being independent.
4. The Cell grows, divides, and develops into a complete organism while it acquires substances and energy from an external environment. The power of Protoplasm/Cytoplasm to attract matter found in its external environment is called Nutrition. The Cell continuously transforms matter to build matter of its own kind for its own benefit to sustain its existence with its own identity and individuality. The Organism represents a social group or a biological community of Cells. The Spiritual nature of Protoplasm/Cytoplasm brings this functional harmony and unity in the Social Group or Biotic Community of Cells by bringing together its Essence and Existence.
5. The Cell Theory is incomplete for it does not describe the conditioned nature of the Cell’s existence. The Cell represents a Living System that is thermodynamically unstable. It requires a constant supply of matter and energy from its external environment to sustain its living functions. The concept of Whole Spirituality formulates the connection between the Cell and its external source of matter and energy.
Whole Dude – Whole Nourishment: There are three Fundamental Principles involved in providing Nourishment, These are 1. Food, 2. The Consumer of Food, and 3. The Provider of Food.
Life comes into existence when energy-yielding molecules and energy-demanding molecules come together in a spiritual relationship.
Whole Dude – Whole Nourishment: A 3-Dimensional View of the Adenosine triphosphate Molecule, the Chemical Energy used in the performance of the cellular functions. There is a creative process involved in the transformation of the radiant Solar Energy into Chemical Energy that living organisms use.
The theoretical claims about Spirit and Soul, the religious and philosophical doctrines of Spiritualism and Spirituality must be verified using the Cell Theory that defines the multicellular human organism. To describe Soul or Spirit as nonmaterial or immaterial Self will not help man to know the real or true man.
Whole Dude – Whole Nourishment – Whole Spirituality: Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods.
In my analysis, the Science of Nutrition reveals the purpose of food as that of a spiritual medium to provide Whole Nourishment that fosters unity between man’s body, mind, and soul.
Whole Dude – Whole Nourishment: The Spiritual Medium to Provide Nourishment to Life: The Discovery of Whole Spirituality at Whole Foods, Ann Arbor.
Whole Foods, Whole People, and Whole Planet come together in a Wholesome Relationship as God is the Energy Provider, the Original Source of Matter and Energy for Life.
Whole Dude – Whole Nourishment: The Spiritual Medium to Provide Nourishment to Life: Rudolf is Reborn as Rudi to describe the spiritual connection between the Cell and its Energy Provider.
Whole Food comprises of the nutritional substances that support a man’s Physical, Mental, Social, Moral, and Spiritual well-being. These five components of well-being constitute the concept of Whole Nourishment which generates the experience of peace, harmony, and tranquility in human Life and the human existence.
Whole Dude – Whole Nourishment: Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods.
The Spiritual Medium to Provide Nourishment to Life
Whole Dude – Whole Foods – Whole Planet – Whole Family – Whole Spirituality: Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods.
To define food as any substance consumed to provide the nutritional support to an organism is incomplete as it fails to describe the totality of the relationship between food and its consumer. The term Food cannot be defined without defining the Organism, the Consumer of Food. I describe the Seven Dimensions of the man. These are, 1. The Physical, 2. The Mental, 3. The Social, 4. The Moral, 5. The Spiritual, 6. The Creative, and 7. The Rational. I define Whole Food as substances consumed by the man to provide support to the Seven Dimensions of the man. Hence, Whole Food is defined as the Spectrum of Seven Colors.
Bharat Darshan – The Spiritual Medium to Provide Nourishment to Life. I am using the term Spiritual Medium to describe Protoplasm for I want my readers to understand the importance of Culture Medium to provide Support to Living Organisms.Bharat Darshan – The Spiritual Medium to Provide Nourishment to Life. I am using the term Spiritual Medium to describe Protoplasm for I want my readers to understand the importance of Culture Medium to provide Support to Living Organisms.Whole Dude – Whole Foods – Whole Planet – Whole Family – Whole Spirituality – Whole Definition: Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods.
What it is to be a Substance? and What it is to Exist? We need to establish knowledge about the man and the world on a firm basis and the information it provides must be tested for its accuracy and consistency with an external reality.
Whole Dude – Whole Foods – Whole Spirituality: Goddess Annapurna is depicted as The Mother Principle of human creation and existence. The celebration of Whole Food as a Spiritual Substance of Human Nourishment. Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods
At Whole Foods, I discovered the spiritual connection between man, food, and Providence. Whole Foods, Whole People, and Whole Planet are connected by a material substance called Protoplasm, a divine plan to provide nourishment to Life.
Whole Dude Defines Whole Food as the Spectrum of Seven Colors. Whole Dude Loves Whole Food he purchases at the Whole Foods Market, Ann Arbor, Michigan, USA. Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods.
I coined the phrase Whole Spirituality to describe the three dimensional spiritual relationship between the multicellular human organism, food, and the Divine Providence.
Rudolf is reborn as Rudi to describe the spiritual connection between Cell and its Energy Provider. The 3-Dimensional Spiritual Relationship between Man, Food, and God.
Spiritualism – The Cell Theory of Spirituality:
The Rudolf and Rudi Connection. The Discovery of the concept of Whole Spirituality, the three dimensional spiritual relationship between the multicellular human organism, food, and the Divine Providence.
In Biology, cell is the basic or fundamental unit of structure, function, and organization in all living things or it is the building block of life. Let me begin with my respectful tribute to some of the people who contributed to ‘The Cell Theory’, one of the foundations of Biological Sciences. Cells were first observed in the 17th century shortly after the discovery of the microscope. Robert Hooke, british curator of instruments at The Royal Society of London, during 1665 coined the word cell. Dutch microscopist Antonie Van Leeuwenhoek (1632-1723) made over 247 microscopes and examined microorganisms and tissue samples. He gave the first complete descriptions of bacteria, protozoa (which he called animalcules), spermatozoa, and striped muscle. He also studied capillary circulation and observed Red Blood Cells.
The Spiritual Medium to Provide Nourishment to Life: Robert Hooke, British curator of instruments at The Royal Society of London coined the term cell during 1665.The Spiritual Medium to Provide Nourishment to Life: Dutch microscopist Antonie Van Leeuwenhoek (1668-80) studied capillary circulation and observed Red Blood Cells.
Improvements in microscopy during early 19th century permitted closer observation and the significance of cells had received better understanding. Matthias Jakob Schleiden (1838), German botanist, Theodor Schwann (1839), German physiologist, and Rudolf Virchow (1855), German pathologist, and others made important contributions to the Cell Theory that describes cell as the building block of all Life.
The Spiritual Medium to Provide Nourishment to Life: Schleiden, Professor of Botany, The University of Jena studied plant structure under the microscope, published “Contributions to Phytogenesis”(1838). He had also published the two-volume text of ‘Principles of Scientific Botany’.The Spiritual Medium to Provide Nourishment to Life: Schwann founder of modern Histology extended the Cell Theory of Plants to animals in his ‘Microscopic Researches into Accordance in the Structure and Growth of Animals and Plants(1839).The Spiritual Medium to Provide Nourishment to Life: Schwann discovered Myelin Sheath covering peripheral axons, now termed Schwann Cells. He coined the term ‘Metabolism’ for the chemical changes that take place in living tissues.The Spiritual Medium to Provide Nourishment to Life: Rudolf Virchow, German pathologist in 1855 coined the biological dictum “OMNIS CELLULA E CELLULA” – All living cells arise only from pre-existing living cells.
The Cell is the smallest unit in the living organism that is capable of carrying on the essential life processes of sustaining metabolism for producing energy and reproducing. Many simple, small, single-celled organisms like Protozoa perform all life functions. In higher, complex, bigger, multicellular organisms, groups of cells are structurally and functionally differentiated into specialized tissues, organs, and organ systems. Thus, the Cell Theory includes the following foundational principles of the Biological Sciences:
1. All living things are made up of cells. Cell is the most elementary or basic unit of Life.
2. Cell is a fundamental unit of structure, function, and organization in all living things including plants and animals.
3. Cells only rise from division of previously existing cells.
4. All cells are similar in composition, form, and function. All cells are basically the same in chemical composition (in spite of variations) in organisms of similar species. For example, all the solid tissues in the human body can be shown to consist largely of similar cells; differing it is true, but that are essentially similar to an Ovum.
5. The cells exhibit functional autonomy. The activity of an organism depends on the total activity of ‘INDEPENDENT’ cells.
6. Energy flow (metabolism and biochemistry) occurs within cells.
7. Cells contain hereditary, biological information (DNA) which is passed from cell to cell during cell division.
The Cell Theory of Spirituality:
The Rudolf and Rudi Connection. The Discovery of the concept of Whole Spirituality, the three dimensional spiritual relationship between the multicellular human organism, food, and the Divine Providence.
The basic or fundamental unit of life in the human organism is derived from the fertilized egg cell that eventually develops into a complete organism. The most significant feature of similarity between the cells of the human body is the presence of a soft, gelatinous, semi-fluid, granular material inside the cell. This substance known as Protoplasm or Cytoplasm, or Cytosol is similar to the ground substance found in the Ovum or the Egg Cell.
The Spiritual Medium to Provide Nourishment to Life: Life begins at Conception. Human Ovum Structure – The Cell Theory of Spirituality is based upon the Substance, Structure, Form, Organization, Function, Action and Interactions of this Single Fertilized Egg Cell that eventually develops into a complete human organism.
Protoplasm, the viscous, translucent, colloidal substance is enclosed in a membrane called Cell Membrane, Plasma Membrane or Biological Membrane. A small spherical body called nucleus is embedded in the Protoplasm of the cell. The three essential features of any living cell in the human body are that of the presence of protoplasm, the nucleus, and the cell membrane.
Protoplasm – The Ground Substance of Spiritualism and Spirituality:
The Spiritual Medium to Provide Nourishment to Life: The Discovery of the concept of Whole Spirituality, the three dimensional spiritual relationship between the multicellular human organism, food, and the Divine Providence.
I seek the existence of Soul or Spirit in a substance that is basic to life activities, and in a material that is responsible for all living processes. I, therefore, propose that the understanding of the true or real nature of this ground substance of all living matter will help man to discover peace, harmony, and tranquility in all of his internal and external relationships while man exists in a physical environment as a member of a social group, social community, and Society. In this blog post, I would like to pay my respectful tribute to Jan Evangelista Purkinje and Hugo Von Mohl for their great contribution to the scientific understanding of the living substance, living material, and living matter.
The Spiritual Medium for Providing Nourishment to Life: Jan Evangelista Purkyne (Czech name), Jan Evangelista Purkinje (German name)also known as Johannes Evangelist Purkinje, b. December 17, 1787, d. July 28, 1869. The pioneer Czech experimental Physiologist whose investigations in the fields of Histology, Embryology,and Pharmacology helped create a modern understanding of the eye and vision, brain and heart function, mammalian reproduction, and the composition of cells.
Purkinje conducted his research on human vision at the University of Prague and later on, he served there as a Professor of Physiology (1850-69). He went to Germany and was appointed the Chair of Physiology and Pathology (1823-50) at the University of Breslau, Prussia. There Purkinje created the world’s first independent Department of Physiology (1839) and the first Physiological Laboratory (Physiological Institute, 1842). He is best known for his discovery of large nerve cells with many branching extensions found in the cortex of Cerebellum of the brain (Purkinje Cells, 1837). He discovered the fibrous tissue that conducts electrical impulses from the ‘pacemaker’ called Atrioventricular node or A-V node along the inside walls of the ventricles to all parts of the heart to help in Cardiac contractile function (Purkinje Fibers, 1839). In 1835, he invented and introduced the scientific term ‘Protoplasm’ to describe the ground substance found inside young animal embryo cells. He discovered the sweat glands of the skin (1833); he discovered the nine configuration groups of Fingerprints used in biometric identification of man (1823); he described the germinal vesicle or nucleus of the unripe ovum that now bears his name (1825), and he noted the protein digesting power of pancreatic extracts (1836).
The Spiritual Medium to Provide Nourishment to Life: Hugo Von Mohl, b. April 08, 1805, d. April 01, 1872, German Botanist noted for his research on the anatomy and physiology of plant cells.
Hugo Von Mohl named the granular, colloidal material that made up the main substance of the plant cell as “Protoplasm” in 1846. Purkinje invented the word, but Hugo gave more clarity, understanding, and knowing the nature of this ground substance.
The Spiritual Medium for Providing Nourishment to Life: Protoplasm or Cytoplasm is the clear, soft, gelatinous living substance found inside all living cells. A most striking characteristic of Protoplasm is its vital property of Nutrition. Nutrition is the power which Protoplasm has of attracting to itself the materials that provide energy and are necessary for its growth and maintenance.
Hugo Von Mohl viewed cell as an “elementary organ” and in Physiology he explained Protoplasm as an organ of Motion or Movement, Nutrition, and Reproduction. It is the preliminary material in cellular generation. He was the first to propose that new cells are formed by division of preexisting cells and he had observed this process of Cell Division in the algal cells of Conferva glomerata. His observations are very important to understand the Cell Theory that explains cells as the basic building blocks of Life. He was the first to investigate the phenomenon of the stomatal openings in leaves.
The Spiritual Medium to Provide Nourishment to Life:Protoplasm or Cytoplasm is the clear, soft, gelatinous living substance found inside all living cells. A most striking characteristic of Protoplasm is its vital property of Nutrition. Nutrition is the power which Protoplasm has of attracting to itself the materials that provide energy and are necessary for its growth and maintenance.
Protoplasm is a complex, viscous, translucent solution of such materials as salts and simple sugars with other molecules, mostly proteins and fats, in a colloidal state, that is dispersed but not dissolved in one another. Carbon, Hydrogen, Oxygen, and Nitrogen constitute more than 90 percent of Protoplasm. It exhibits properties such as Protoplasmic Streaming or Cytoplasmic Streaming or Motion that is called “Amoeboid Movement.” It has the intrinsic power to change its shape and position. It has the power of Nutrition by which it can attract and obtain the materials necessary for its growth and maintenance from surrounding matter/environment. These functions involve acquiring, processing, retaining, and using information to perform tasks in a sequential manner for a predetermined purpose and hence describe Consciousness, Memory, and Intelligence. The terms Soul and Spirit belong to the materialistic realm where the Physical Reality of man’s biological existence is established. I have not yet discovered any good reason to use the terms Soul and Spirit as a metaphysical or transcendental Reality.
The Ground Substance of Spiritualism and Spirituality:
The Ground Substance of Spiritualism and Spirituality. The vital characteristics, the animating principles of Protoplasm could be known by observing Amoeba proteus. The Living Substance works as an organ of Motion or Movement, as an organ of Nutrition, and as an organ of Reproduction to generate new cells which have a life span of their own. In these physiological functions, I describe the characteristics such as Cognition, Consciousness, Memory, and Intelligence which have a Spiritual role as they bring functional unity and harmony in the interactions between different parts of the same individual organism while it exists in an environment as a member of a biological community.
The vital characteristics, the animating principles of Protoplasm could be known by observing Amoeba proteus. The Living Substance works as an organ of Motion or Movement, as an organ of Nutrition, and as an organ of Reproduction to generate new cells which have a life span of their own. In these physiological functions, I describe the characteristics such as Cognition, Consciousness, Memory, and Intelligence as spiritual attributes of Life as they bring functional unity and harmony in the interactions between different parts of the same individual organism while it exists in an environment as a member of a biological community.
The Spirituality of Substance, Function, Organization, Action, and Interactions:
The Rudolf and Rudi Connection. The Discovery of the concept of Whole Spirituality, the three dimensional spiritual relationship between the multicellular human organism, food, and the Divine Providence.
To establish the biological existence of the human organism, I add the concept of Spiritualism and Spirituality to the Cell Theory. The Single Fertilized Egg Cell has ground substance that is of Spiritual nature and the Spiritualism and Spirituality consists of the following functional, and organizational characteristics:
1. The Cell is Conscious of its own existence and knows its internal condition and knows it external environment.
2. The Cell is intelligent and it has the cognitive abilities like perception and memory to acquire information, to retain information, to recall information, and to use information in the performance of its complex tasks in a sequential manner.
3. The Cell has the ability to show characteristics such as mutual cooperation, mutual tolerance, and display functional subordination and subservience while being independent.
4. The Cell grows, divides, and develops into a complete organism while it acquires substances and energy from an external environment. The power of Protoplasm/Cytoplasm to attract matter found in its external environment is called Nutrition. The Cell continuously transforms matter to build matter of its own kind for its own benefit to sustain its existence with its own identity and individuality. The Organism represents a social group or a biological community of Cells. The Spiritual nature of Protoplasm/Cytoplasm brings this functional harmony and unity in the Social Group or Biotic Community of Cells by bringing together its Essence and Existence.
5. The Cell Theory is incomplete for it does not describe the conditioned nature of the Cell’s existence. The Cell represents a Living System that is thermodynamically unstable. It requires a constant supply of matter and energy from its external environment to sustain its living functions. The concept of Whole Spirituality formulates the connection between the Cell and its external source of matter and energy.
Life comes into existence when energy-yielding molecules and energy-demanding molecules come together in a spiritual relationship.
Whole Dude Defines Whole Food as the Spectrum of Seven Colors. A 3-Dimensional View of the Adenosine triphosphate Molecule, the Chemical Energy used in the performance of the cellular functions. There is a creative process involved in the transformation of the radiant Solar Energy into Chemical Energy that living organisms use.
The theoretical claims about Spirit and Soul, the religious and philosophical doctrines of Spiritualism and Spirituality must be verified using the Cell Theory that defines the multicellular human organism. To describe Soul or Spirit as nonmaterial or immaterial Self will not help man to know the real or true man.
Whole Dude – Whole Foods – Whole Planet – Whole Family – Whole Spirituality: Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods.
In my analysis, the Science of Nutrition reveals the purpose of food as that of a spiritual medium that fosters unity between man’s body, mind, and soul.
The Spiritual Medium to Provide Nourishment to Life: The Discovery of Whole Spirituality at Whole Foods, Ann Arbor.
Whole Foods, Whole People, and Whole Planet come together in a Wholesome Relationship as God is the Energy Provider, the Original Source of Matter and Energy for Life.
The Spiritual Medium to Provide Nourishment to Life: Rudolf is Reborn as Rudi to describe the spiritual connection between the Cell and its Energy Provider.
Whole Food comprises of the nutritional substances that support a man’s Physical, Mental, Social, Moral, and Spiritual well-being. These five components of well-being are important to generate the experience of peace, harmony, and tranquility in human Life and the human existence.
Whole Dude – Whole Foods – Whole Planet – Whole Family – Whole Spirituality: Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods.
How to regulate the Feeding Behavior? The Principles of Obesity Prevention
Whole Dude – Whole Foods – Whole Planet – Whole Family – Whole Spirituality – Whole Definition: Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods.
This article examines the relationship between food, man, and the world in which he exists to formulate a Food Theory that may provide the principles for preventing the medical problem described as obesity.
Whole Dude – Whole Foods – Whole Spirituality: Goddess Annapurna is depicted as The Mother Principle of human creation and existence. The celebration of Whole Food as a Spiritual Substance of Human Nourishment. Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods.
What it is to be a Substance? and What it is to Exist? We need to establish knowledge about the man and the world on a firm basis and the information it provides must be tested for its accuracy and consistency with an external reality.
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention.Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. What are the non-optical functions of the light? Photosynthesis is the Divine non-optical function of Light that supports the existence of Life.
We need a methodology to study philosophy and to understand philosophical statements. Logical Positivism, also known as Scientific Empiricism aims to clarify concepts in both everyday and scientific language. It describes analysis of language as the function of philosophy. This analysis of language and of concepts is important to understand questions of belief and ideology which affect what we think we ought to do individually and socially. I use this method of ‘Applied Philosophy’ to analyze the concept of Spiritual Optics, the spiritual dimension of the relationship between the man and the substances he consumes as food.
SPIRITUALITY SCIENCE – THE ART OF KNOWING: HOW DO PLANTS KNOW WHAT THEY KNOW? PLANTS KNOW ABOUT LIGHT, THE LENGTH OF DAY, AND THE DURATION OF DARKNESS CALLED NIGHT. THERE IS NO “INTELLECT” INVOLVED IN THIS PROCESS OF KNOWING. THE ABILITY OF KNOWING LIGHT OR PHOTORECEPTION IS EXPLAINED BY PHOTOCHEMISTRY.
For example, photosynthesis represents the most important non-optical function of Light instituted by Providence in support of the existence of Life on Earth. The prevention of Obesity demands the formulation of a correct and valid theory of Food.
WHOLE FOOD AND WHOLE SCIENCE:
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. The Chemical Energy Molecule called Adenosine triphosphate or ATP. The creative mechanism called Photosynthesis transforms one form of energy into another form of energy used by the living organisms.
Life comes into existence when energy-yielding molecules and energy-demanding molecules come together in a spiritual relationship.In my analysis, the Science of Nutrition reveals the purpose of food as that of a spiritual medium that fosters unity between man and Divine Providence using a corporeal substance called Protoplasm or Cytoplasm.
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. What are the non-optical functions of the light? Photosynthesis is the Divine non-optical function of Light that supports the existence of Life
The definition of food as any substance consumed to provide the nutritional support to an organism is incomplete as it fails to describe the totality of the relationship between food and its consumer. I describe the Seven Dimensions of the man. These are, 1. The Physical, 2. The Mental, 3. The Social, 4. The Moral, 5. The Spiritual, 6. The Creative, and 7. The Rational. I define Whole Food as substances consumed by the man to provide support to the Seven Dimensions of the man. Hence, Whole Food is defined as the Spectrum of Seven Colors for the generation of food involves a creative mechanism operating the fundamental Light and Matter photochemical interactions.
WHOLE FOOD AND THE WHOLE THEORY:
Whole Dude – Whole Foods – Whole Planet – Whole Family – Whole Spirituality: Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods.
I define the term ‘Whole Food’ as follows taking into consideration the seven dimensions of Food in supporting the biological existence of the man in his community, and environment. Indeed, no man is truly capable of an existence that excludes the social community and the physical environment in which he exists:
1. Whole Food provides the nutritional substances for the Physical well-being of man and supports his living functions.
2. Whole Food provides the psychological satisfaction, the mental contentment that a man needs to support his Mental well-being.
3. Whole Food provides the stimulus for social relationships and social bonding that a man needs to support his Social well-being.
4. Whole Food provides the ability to a man to express his moral and ethical principles to support his Moral well-being.
5. Whole Food provides the spiritual basis for the man’s relationship with Divine Providence to support the Spiritual well-being of man.
6. The creative dimension of the man is reflected by the imagination and the skills deployed by the man in the preparation of his food and the artistic presentation of the food.
7. In the final analysis, the man as a Rational Being will choose to eat to live with a purpose rather than to live to eat without any purpose in life.
Whole Food comprises of the nutritional substances that support a man’s Physical, Mental, Social, Moral, and Spiritual well-being. These five components of well-being are important to generate the experience of peace, harmony, and tranquility in human Life and the human existence.
OBESITY-THE PROBLEM OF EXCESSIVE EATING:
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. It requires the formulation of Eating Behavior that is consistent with inner cues of Hunger and Satiety. A Balanced Diet may or may not provide the experience called Satiation.
The word ‘obese’ is derived from Latin word “obedere” which means to devour (ob + edere means about + eat). Obesity is the result of excessive eating. Obesity is the commonest effect of continued over consumption of calories. This blog post intends to explore the preventive principles that could be applied to curb the behavior that leads to excessive eating. Preventive principles could be different from principles used in the treatment of obesity. Prevention of excessive eating would be of value in the clinical management of obese patients but should not be viewed as a curative regime. Obese patients may need other interventions apart from restriction of dietary intake. In my opinion, the prevention of obesity involves the ability to formulate eating behavior that is consistent with inner cues of hunger and satiety.
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. The measurement of body weight is the simplest and the least direct method of measuring the fat content in the body.
Obesity is the most common nutritional disorder of modern times. Obesity can occur at any stage of life. Obesity in childhood and adolescence has become common and is viewed with a sense of alarm. Obesity is defined as a condition in which there is an excess deposit of fat in (and on) the body with an increase in body weight more than 10 percent above the normal for the age, sex, height, and stock or clan. Body weight is a valuable screening measure for obesity. The measurement of body weight is the simplest and the least direct method of measuring the fat content in the body. It must be very carefully noted that we have tools to measure body weight and that we have no tools to measure or estimate the sensations called Hunger and Satiety. Hence, the preventive principles are not evidence-based, and are only reason-based. It will not be practical to provide consistent results while we depend upon criteria such as Hunger and Satiety which are not measurable quantities that could be stated using a precise, scientifically accurate method. To deal with the problem of obesity, we have to deal with the issues of Hunger and Satiety to regulate feeding behavior and to control caloric intake. Patterns of eating behavior and physical activity are influenced by social, cultural, and economic factors. Hence, obesity is a complex issue but the complexity should not stop us from preventing the problem of excessive eating. Genetic factors may influence total body fat and its distribution. However, the epidemic of obesity is not caused by the prevalence of a defective gene or genes.
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. The brain mechanisms involved in Feeding Motivation include a complex network that involves the Limbic System that controls the Emotional States and the Hypothalamus at the base of the brain.Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. Hypothalamus has nerve centers that are sensitive to changes in blood chemistry, water, products of digestion, and temperature. Hunger, Thirst, and Satiety are regulated by Hypothalamus.
Readers may like to view the Map of Hypothalamus
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. Hypothalamus has nerve centers that are sensitive to changes in blood chemistry, water, products of digestion, and temperature. Hunger, Thirst, and Satiety are regulated by Hypothalamus.
The brain mechanisms involved in feeding motivation include a complex network that involves the Limbic System that controls the emotional states and the Hypothalamus at the base of the brain. Hypothalamus has nerve centers sensitive to changes in blood chemistry, water, products of digestion and temperature. A nerve center called Ventromedial Nucleus is described as the ‘Satiety Center’. It is the clearing house for satiety signals. Lesions in this area cause gross overeating or hyperphagia. The nerve center in the lateral hypothalamic area is described as the ‘Eating Center’ or ‘Hunger Center’. It facilitates feeding responses. Electrical stimulation of this area elicits voracious feeding and lesions in this area cause prolonged noneating or aphagia. Glucose receptors are present in the cells of the above nuclei which monitor the level of the circulating blood glucose in order to produce the appropriate response. Excessive eating can be controlled by direct electrical stimulation of Satiety Center.
Internal changes that initiate behavioral changes are commonly termed ‘Drive’ or ‘Motivation’. Hunger is a sensation associated with various physiological changes that stimulate the drive to search for food. Most people are familiar with the sensation described as hunger pangs. The responsiveness of the brain mechanisms for feeding is governed by messages reporting the nutritional state of the body. Responsiveness is higher with increasing lack of food in the body. The contents of these messages are primary determinants of the level of feeding motivation. Hunger and Satiety represent high and low levels of feeding motivation.
FOOD AND ENERGY CONSUMPTION-THE WHOLE REGULATION:
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. Hypothalamus has nerve centers that are sensitive to changes in blood chemistry, water, products of digestion, and temperature. Hunger, Thirst, and Satiety are regulated by Hypothalamus.
Life depends upon a virtually uninterrupted supply of materials for its metabolism. For purposes of survival, metabolic expenditure cannot exceed food intake for very long period. In principle, feeding must proceed throughout life at a pace equal to that of metabolism. In many cases, food intake does not closely follow caloric expenditure. It is permissible for food intake to lag when there are reserves in the body. Discrepancies between intake and expenditure leads to distortion of the basic pattern of caloric regulation. The capacity of the digestive system may set a limit on nutrient supply to the body. Such limitations play a role in human feeding behavior. In man, the capacity of food-gathering and of the digestive system exceed the demands of metabolism. The man has the inherent physiological capabilities and anatomical capacity to consume food and calories in excess of his normal metabolic requirements. It should not be a surprise to observe a similar predisposition to obesity among human pet animals like dogs and cats.
The lack of fuel in the body can be corrected by intake of food that provides energy. Ingested food (calories) passes from 1. the mouth to 2. the digestive tract to 3. the blood stream, and then to 4. storage sites such as liver and fat tissues. These four regions are continuously monitored using a variety of receptors:
1. Organs for taste, smell, and touch in the mouth region. 2. Distension receptors or mechanoreceptors in the stomach and gastrointestinal tract that monitor the volume. 3. Chemoreceptors that monitor the nature of contents of the blood stream. 4. Receptors in Hypothalamus and Liver for monitoring of fat tissues.
The signals converge on the brain mechanism for the feeding motivation using nervous and humoral or chemical pathways. The signals have two kinds of effects; 1. if signals from the four regions report increased fuel contents, the feeding motivation is lowered and satiety is raised, and 2. if taste, visual, and smell receptors are stimulated by palatable food the feeding motivation is increased. The signals for satiation override the signals for hunger and feeding stimulation. Food intake stops when feeding motivation drops below a critical level. When food is catabolized, it causes fuel depletion. Gastric emptying and emptying of Colon and Rectum also stimulate hunger sensation causing resumption of feeding. Once feeding is resumed, intake is enhanced by the positive effects of food stimulus. The interplay of positive and negative feedbacks from food intake tends to maintain a balance between caloric intake and energy output so that body fuel content or body weight in fully grown individuals remains constant. Few people adjust their food intake to meet their needs on a daily basis. The excess Glucose that is not utilized by the body is stored in the Liver as Glycogen which is further converted into fat. The excess amount of fat remains stored in the body fat tissues. The control of the amount of energy reserve in the fat tissue and the nature of control system is not fully understood. The physiological stimuli and changes associated with hunger could be stimuli for coordinating the long-term regulation of the reserve energy. However, it must be noted that a man can accumulate energy reserves and yet experience hunger sensation that is normally generated by a lack of fuel in the body.
FOOD AND ENERGY-THE WHOLE BALANCE:
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. Hypothalamus has nerve centers that are sensitive to changes in blood chemistry, water, products of digestion, and temperature. Hunger, Thirst, and Satiety are regulated by Hypothalamus. The regulation of energy balance. Energy homeostasis relies on controls exerted on both energy intake and energy expenditure. The control of energy expenditure can be exerted on the muscle activity as well as on BAT thermogenesis. Those controls are insured by different brain structures that compose the cortical executive circuits, reward circuits, and autonomic circuits. The activity of the brain networks is influenced by peripheral homeostatic signals that inform the central nervous system about energy stores. Palatable food also influences cognitive aspects including motivation and pleasure. 2AG, 2-arachidonoylglycerol; ACC, anterior cingulate cortex; CB1R, cannabinoid receptor 1; D2R, dopamine receptor 2; DVC, dorsal-vagal complex; MBH, mediobasal hypothalamus; NAc, nucleus accumbens; PFC, prefrontal cortex; SN, substancia nigra; VTA, ventral tegmental area.
Exercise consumes carbohydrates and most of the fat. Obesity or excess fat accumulation is the consequence of imbalance between energy intake and energy expenditure. Obesity develops if physical activity or energy expenditure becomes very low and the person is not able to reduce food intake or energy intake. In modern times, people are able to obtain their food with little or no physical effort. New sources of power do the work formerly carried out by human muscles. Large number of people spend time without physical activity. People have appetites and are seldom really hungry. A very small excess of calories if habitual, can lead eventually to a large accumulation of fat. It has been reported that if a person eats a slice (20 g) of bread that is not needed each day or goes by car instead of walking for 20 minutes, the daily extra 48 KCal or 200 KJ will build up over 10 years to 20 Kg of fat deposited. In simplest terms, obesity is the outcome of consistent consumption of more calories than are required to meet the energy expenditure of that particular person.
FOOD AND OBESITY-THE WHOLE PROBLEM:
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. Hypothalamus has nerve centers that are sensitive to changes in blood chemistry, water, products of digestion, and temperature. Hunger, Thirst, and Satiety are regulated by Hypothalamus.
The causation of obesity is still difficult to explain. There are differences between obese and non-obese individuals in respect of hormone secretion and metabolism. Endocrine changes at puberty, during pregnancy, and at menopause may contribute to obesity at these stages of life. The effects of obesity are better understood than the causes of obesity. In Medicine, obesity is described as a clinical condition with several probable causes. Some of the organic pathological causes of obesity include endocrine disorders such as hypopituitarism, hypothyroidism and hypogonadism. Hormonal changes associated with menopause, Anterior Pituitary tumor causing Cushing’s Syndrome, Dercum’s disease (Adiposis dolorosa), and Frohlich’s Syndrome (Posterior Pituitary Deficiency) are causes of obesity. In a few obese individuals, psychiatric mood disorders such as depression and anxiety could be present. Depressed or anxious patients or the emotionally deprived may seek solace in food and such emotional factors play a role in the predisposition towards excessive eating. Overeating could be a symptom of boredom or emotional frustration. In mental diseases, bizarre disturbances of appetite, taste , and food preference may be seen. Some well-known examples are Anorexia nervosa and Bulimia. Self-imposed starvation may develop after bereavement or after disappointment in love. It must be understood that the functions of food include that of obtaining a sense of emotional satisfaction apart from satiation of hunger. The most important and the most universal cause of obesity among otherwise normal people is overeating and lack of exercise.
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. The measurement of body weight is the simplest and the least direct method of measuring the fat content in the body.
The prevalence of obesity has increased worldwide in the past ~50 years, reaching pandemic levels. Obesity represents a major health challenge because it substantially increases the risk of diseases such as type 2 diabetes mellitus, fatty liver disease, hypertension, myocardial infarction, stroke, dementia, osteoarthritis, obstructive sleep apnea and several cancers, thereby contributing to a decline in both quality of life and life expectancy. Obesity is also associated with unemployment, social disadvantages and reduced socio-economic productivity, thus increasingly creating an economic burden. Thus far, obesity prevention and treatment strategies — both at the individual and population level — have not been successful in the long term. Lifestyle and behavioral interventions aimed at reducing calorie intake and increasing energy expenditure have limited effectiveness because complex and persistent hormonal, metabolic and neurochemical adaptations defend against weight loss and promote weight regain. Reducing the obesity burden requires approaches that combine individual interventions with changes in the environment and society. Therefore, a better understanding of the remarkable regional differences in obesity prevalence and trends might help to identify societal causes of obesity and provide guidance on which are the most promising intervention strategies. (Blüher, M. Obesity: global epidemiology and pathogenesis. Nat Rev Endocrinol 15, 288–298 (2019). https://doi.org/10.1038/s41574-019-0176-8
WHOLE FOOD AND WHOLE SATISFACTION:
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. What is the original source of the experience called Satiety?
The word desire or craving involves the feelings to wish, covet, or long for something. Similarly, the word appetite describes a desire to satisfy some craving of the body. The term greed describes excessive desire especially for wealth or food. The term lust describes a passionate sexual desire without idealized or spiritualized feelings. The word glutton describes someone who indulges excessively in eating and drinking. All of these kinds of passionate desires or appetites have a common feature. The behavior that is attributable to greed, lust, and gluttony could be influenced by man’s sense of contentment. The role of contentment could be explained by understanding the following quote from the Books of The Old Testament, The Ecclesiastes, Chapter 5, verse 18:
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. Eat and Drink to find Satisfaction in Life.
“Then I realized that is good and proper for a man to eat and drink, and to find satisfaction in his toilsome labor under the sun during the few days of his life God has given him – for this is his lot.”
While it is good and proper for a man to eat and drink, the acts of gratification; eating, and drinking may not provide a sense of satisfaction that is complete and that overcomes the craving for food and drink. Contentment is the factor which determines as to the degree of gratification that is needed for producing the effect called satisfaction. The man can choose to set the bar called contentment at a high or a low-level and experience the effect called satisfaction while seeking gratification of his desires. To conquer the insatiable enemy called desire, to achieve the result called satisfaction, one must overcome the senses, the mind, and intelligence which are the sitting places of desire. To accomplish the purpose of restraining the senses, the mind, and intelligence, we must know the man as the Whole Organism. I divide man into two categories; 1. The Self (the Lower-Self)that represents the man as a physical, mental, and social being, and 2. The Knowing-Self ( the Higher-Self)that represents the man as the moral, and spiritual being. The Knowing-Self is the Higher-Self and hence it can exercise control and restraint over the Lower-Self which includes the physical body, the sense organs, the mind and intellect, which are the seats of all passionate desires.
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. The problem of food cravings and food addiction.
In obese people, eating is less often determined by internal cues like hunger and satiety. For many obese people, the craving to eat is very strong and is similar to the craving for alcohol in the alcoholic and for a cigarette in a person addicted to tobacco smoke. The problem of food cravings is a significant factor in the management of obesity. The failure to respond to a dietary plan that restricts food and caloric intake is often caused by the inability to overcome food cravings which leads to non-compliance. The eating or feeding behavior is influenced by the man’s sense of contentment. A person who lives in a state of self-contentment experiences a little less hunger and experiences a sense of satiation or satisfaction more easily after a routine meal. Such a person who is self-contented is not prone to food cravings. He may not need a dietary plan and may not need to count the calories he consumes. He is more likely to maintain a steady body weight without the requirement of changing the level of physical activities. The man has the ability to set his expectations at a level and experience contentment with what he has. If there is contentment, the desire for food and drink is easily satisfied. A contented man is more likely to meet the daily requirements of calories for optimal physiological functioning without gaining body weight. The prevention of obesity could be helped by a proper understanding of food, its nature, and its functions.
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. Food is a substance eaten for nourishment, for psychological satisfaction, and to support Social Bonding. There is Spiritual Relationship between Food and its Consumer. The Concept of Balanced Diet is silent about the relationship between Food and its Consumer.
Food is a substance eaten for nourishment. Food serves functions other than nutrition. Food plays a vital role in the development, and the maintenance of social interactions, social relationships, and is the fundamental basis for the man’s spiritual relationship with a source of energy and its provider which sustains life and existence.
WHOLE FOOD AND WHOLE LIFE:
Most important biological processes involve Oxidation-Reduction or Redox Reactions to acquire Oxidative energy from other substances termed nutrients. The burning of a substance in air is rapid Oxidation or Combustion which is not of much use for living systems. Plants and Animals use a form of Oxidation called Respiration to liberate energy stored in food materials.
Food describes any substance which a living organism can convert into energy and new tissue using the process of metabolism. The body fluids surrounding each cell are the immediate source of nutrients. The nutrients supplied by food are either used as building blocks in synthesizing large molecules or they are oxidized producing a form of energy that is further used for powering the activities of the cell. To maintain life, an organism not only repairs or replaces (or both) its structures by a constant supply of the materials of which it is composed but also keeps its life processes in operation by a steady supply of energy. The Living Systems must be supplied energy for continual synthesis of new organic molecules and to replace or to repair broken organic molecules. Dr. Oliver Wendell Holmes, Professor of Anatomy and Physiology, Dean of the Harvard Medical School (1847 to 1882) defines life, “To live is to function; and that is all there is in living.” At the cellular level, the living functions include uptake and conversion of nutrients, synthesis of new molecules, production of energy, and regulation and coordination of metabolic sequences.
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. The Living Cell is a thermodynamically unstable system. This means that without a continuous input of Energy, a Living Cell will degrade spontaneously into a collection of nonliving molecules.
The processes of synthesis and breakdown of the organic molecules of the cell are termed metabolism. Metabolism is divided into two categories; 1. Anabolism- it describes the processes of maintenance and growth, and 2. Catabolism- it describes the processes that breaks down molecules to release energy. The Living Cell depends on a virtually uninterrupted supply of materials for its metabolism. The Living Cell is a thermodynamically unstable system. This means that without a continuous input of energy, a Cell will degrade spontaneously into a nonliving collection of molecules. Food supplies organic molecules and other substances as nourishment to sustain life. Life is characterized by the presence of complex transformation of organic molecules and by the organization of such molecules into successively larger units of protoplasm, cells, organs, and tissues.
WHOLE FOOD AND WHOLE POWER:
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. Protoplasm or Cytoplasm is the clear, soft, gelatinous living substance found inside all living cells. A most striking characteristic of Protoplasm is its vital property of Nutrition. Nutrition is the power which Protoplasm has of attracting to itself the materials that provide energy and are necessary for its growth and maintenance.
All the tissues and organs of which the human body is composed, consists of building blocks called Cells. Each Living Cell contains soft, gelatinous, semi-fluid, viscous, clear or translucent, colloidal living substance or matter called Protoplasm or Cytoplasm or Cytosol. A most striking characteristic of protoplasm is its vital property of ‘Nutrition’. Nutrition is described as the ‘power’ which protoplasm has of attracting to itself the materials that provide the energy, and the substances for its growth and maintenance from surrounding matter/environment. Nutrition, as a biological function and activity, is the evidence for the operation of Consciousness at cellular level. The Living Cell is conscious or aware of its own existence in its given environment, it is conscious or aware of its energy dependent state of internal condition, and consciously uses its power of nutrition to attract substances from its immediate environment. The Living Cell displays its living functions while it exists as a conscious entity. The Cell Death is characterized by the absence of the power of nutrition, and in the absence of energy input or food intake, the Cell dies. Consciousness and Food are related to each other. Consciousness gives the power of attracting Food and Food provides the ability to live with Consciousness which is the most important characteristic of life. The human organism exists because of the functions of the trillions of cells. The purpose of consciousness is to foster functional unity of the multicellular organism and establish it as an individual. This conscious individual experiences hunger, and thirst which provide the drive or motivation to initiate his feeding behavior. Each individual cell uses its own power of Nutrition to attract the nutrients from the body fluids that are present in its immediate environment. Certain metabolic disorders and conditions like Diabetes are associated with problems of food intake at cellular level. The man may feed himself, and nutrients like glucose accumulate in the blood stream and fail to provide the nourishment needed by the cells. Similarly, there are several mental diseases that are associated with a variety of eating disorders, and bizarre disturbances of appetite, taste, and food preference.
WHOLE FOOD AND WHOLE NUTRITION:
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. The Protoplasm has the power of Nutrition. The Cell Membrane or the Biological Membrane is not a simple physical barrier separating the Cell from its surrounding environment. The Cell Membrane plays an active role in food intake.
The Biological Membrane, the Cell Membrane or the Plasma Membrane separates the living cell from its environment and from other cells. It helps to maintain a constant ‘milieu’ in which intracellular reactions occur. The Plasma Membrane allows a highly controlled exchange of matter across the barrier it poses; some compounds are able to pass through the Membrane easily, others are completely blocked. Food must provide adequate amounts of all chemical elements needed by the Cells. Of the approximately 35 elements known to occur in cells, four (Oxygen, Carbon, Hydrogen, and Nitrogen) make up about 95 percent of the cell weight. Nine elements (Calcium, Phosphorus, Chlorine, Sulfur, Potassium, Sodium, Magnesium, Iodine, and Iron) contribute about 4 percent of the cell weight. The remaining 20+ elements together constitute less than 1 percent of cell weight and are called trace elements because they occur in minute quantities. However, many such as Copper, and Zinc fulfil vital functions. Animal cells do not have the ability to synthesize certain complex organic molecules from simple inorganic compounds. Certain large organic molecules that serve as building blocks that must be supplied by food are known as essential dietary components. They include Vitamins, Essential Amino Acids, and Essential Fatty Acids. The man has restricted synthetic powers as compared to the bacteria and hence needs greater number of essential foodstuffs. The man derives energy solely from the breakdown of complex organic molecules, mainly Carbohydrates and Fats. Fuel for the maintenance of life comes from other living organisms or their products. Human life ultimately depends on the existence of green plants that can use inorganic source of energy such as Solar radiation. Terrestrial life depends upon an extraterrestrial source of Energy. All terrestrial organisms live as energy dependent entities and live by establishing a relationship with a source of energy.
WHOLE FOOD AND THE WHOLE CONNECTION:
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. The human life begins as a single cell, the fertilized Ovum. How does it obtain food and energy? The man exists because of a “Connection” with an Energy Provider.Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. The man’s life journey begins as an Embryo which gets implanted into the maternal tissues by about 6 days after its conception. Thus, mother is the source of Food and Energy to establish human life.
The man exists because of a “Connection.” In nature, a man exists as an energy seeker or heterotroph. The human existence becomes possible only when a man is connected to an energy provider. This biological connection to a source of energy is made possible when biological information is implanted in the single, fertilized Egg Cell which begins its journey to grow and develop into a new organism. If Sun is viewed as a source of energy for all life on this planet, the man is not directly connected to that source of energy. The man exists as a multicellular organism and each cell derives its energy from powerhouses called mitochondria; the intracellular membrane bound organelles found in all living cells.
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. The man exists as energy seeker. Mitochondria are the powerhouses found inside all living cells. They establish the ‘Connection’ between the energy seeker and the energy provider.
The mitochondria have the necessary biological information to transform oxidative energy into a form of chemical energy that the cell could further use for its living functions. In nature, the man obtains food from other organisms. Only the green-celled plants known as autotrophs can directly convert light energy into chemical energy that they can further use.
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. Green-celled plants are known as autotrophs. They can directly convert light energy into chemical energy that they further use to manufacture plant substances and products. The Chloroplasts act like Solar Panels to capture inorganic light energy. The Chloroplasts act like a relay station in the flow of energy from the Sun to Man who uses the Mitochondria to establish this Connection.
The man is connected to these Chloroplasts of green plant cells that have the ability to trap Sun’s light energy. Sun’s energy is an extraterrestrial source of energy and it is provided to man by the intervention of Chloroplasts and the Mitochondria which man directly acquires from his mother’s Egg Cell. These biological mechanisms are put in place and they operate outside the intellectual or physical abilities of the man. In my blog post titled, ‘The Divine Mother of Life, Energy, and Knowledge, I describe the mother as the source of life, energy, and knowledge, which is often described as the Cytoplasmic Inheritance.
WHOLE FOOD AND WHOLE BONDING:
The Rudolf-Rudi Connection at Whole Foods. The Prevention of Obesity.The act of consuming or eating Food establishes Social Bonding between the Food Provider and the Food Consumer. Feeding has a social purpose and it initiates social interactions. There is always a spiritual relationship between Mother and the Baby, a relationship based upon sympathy, understanding, affection, feelings, and Love.
Apart from nutrition, a man consumes food for psychological satisfaction or to derive a sense of emotional contentment, and for the benefit of other individuals. A pregnant woman consumes food to provide a direct benefit to the baby growing in her womb. This placental connection between mother and her fetus establishes an anatomical relationship and a social relationship and social bonding between the two both during the duration of pregnancy and after the delivery of the baby. The man’s feeding behavior and feeding activities are influenced by social, and external environmental factors. Both, the timing of feeding, and the choice of food are affected by social facilitation. Food-directed activities in social situations demonstrate the ability of food to establish connection between food provider and the food consumer. Hunger and Satiety operate the physiological mechanisms related to food intake. The psychological, and emotional contentment derived from food is related to Social Bonding and Social Relationships that are fostered by Food. I describe spirituality as a relationship based upon sympathy, understanding, affection, feelings of care and love. Food has the intrinsic ability to nurture a spiritual relationship between the provider of the food and its consumer. There is also a direct emotional relationship between man and the food he consumes. The causes for excessive or overeating are not yet fully understood. The physiological mechanisms of hunger and thirst cannot fully account for the feeding behavior of man. Just like lust, and greed, the man has psychological desire or craving for food and develops an intimate relationship with the food and drink he consumes. However, a man can always express his craving for food in a spiritual context and seek the satisfaction provided by knowing the nature of God-Connection.
WHOLE FOOD AND WHOLE COVENANT
The Rudolf-Rudi Connection at Whole Foods. The Prevention of Obesity. Discover the purpose of food. Salt enjoys a special status among all food substances that man consumes. The intimate connection of salt with the idea of a “COVENANT” or binding contract or binding relationship, as a mark of Loyalty and Faithfulness, between man and God and between man and man is recognized in all human cultures.
Salt is universally used as a seasoning and as a preservative of food. Salt enjoys a special status among all food substances that man consumes. The status of salt as a life-giving and life-sustaining substance is well-founded. The intimate connection of salt with the idea of a “COVENANT” or binding relationship between man and God, and between man and man is recognized in all human cultures. The idea of “a covenant of salt forever” is found in The Fourth Book of Moses, The Old Testament Book of Numbers, Chapter 18, verse 19: “It is an everlasting covenant of salt before the Lord for both you and your offspring.” Similarly, The Third Book of Moses, The Old Testament Book of Leviticus, Chapter 2, verse 13 reads: “Season all your grain offerings with salt. Do not leave the salt of the covenant of your God out of your grain offerings, add salt to all your offerings.” The special status enjoyed by salt is reflected in the phrases popularly used in the languages of different people; “Untrue to Salt”(Persian), “Trespass not against the Salt”(Greek), “There is Salt between Us”(Arabic), “Injury or Harm to Salt”(“Namaq or Namak Haram” – Indian). Jesus very effectively communicates the relationship between the status of salt and the nature of man. The nature of man is understood in terms of his behavior, character, and conduct. It is expected of man to display respect, faithfulness, and loyalty in his relationship with other persons where the relationship is established by the covenant of salt. Jesus directly instructs people to reject any person who has lost the fundamental characteristics of character and integrity and states His view by comparing the man to salt. “You are the salt of the earth, but if salt has lost its taste, how shall its saltiness be restored? It is no longer good for anything except to be thrown out and trampled under people’s feet.” (Matthew 5:13)
Theory of Whole Food and the Prevention of Obesity. Food that is seasoned with salt and is given as offering to God, and food that is seasoned with salt and is given to another person establishes a binding contract, a covenant, a binding relationship which has validity of its own. The nature of this social bonding and binding social relationship is reflected in the words used by Jesus while He delivered His Sermon on the Mount: “You are the Salt of the earth. But, if the Salt loses its saltiness, how can it be made salty again? It is no longer good for anything except to be thrown out and trampled by men.”
By accepting food, by consuming food, and by deriving nourishment and sustenance from food, the man establishes a binding relationship forever with his food provider.
WHOLE FOOD AND WHOLE RELATIONSHIP:
Theory of Whole Food and the Prevention of Obesity. The purpose in Life and the purpose in eating. The Last Supper- The Gospel according to Saint Mark, Chapter 14, verse 22, and the Gospel according to Saint Matthew, Chapter 26, verse 26 and the Gospel according to Saint Luke, Chapter 22, verse 19, depict the scene called the Last Supper. The ritual instituted by Jesus establishes the Sacrament of the Lord’s Supper or Holy Communion. Judas Iscariot, one of the twelve apostles was the betrayer and is depicted by the person who is leaving the dinner table with bread in his hand.
Jesus Christ describes Himself as the Spiritual Food of man. In the Gospel according to Saint John, Chapter 6, verse 35, Jesus declares, “I am the bread of life. He who comes to me will never go hungry, and he who believes in me will never be thirsty.” Further, the Book of John, Chapter 6, verse 48 also reveals the purpose of Jesus, “I am the bread of life. I am the living bread that came down from heaven.” Virtually all Christian Churches celebrate the practice of Communion such as Mass, Eucharist, or Lord’s Supper in some form or the other.
Theory of Whole Food and the Prevention of Obesity. A purpose for living and a purpose for eating.
The First Epistle of Apostle Paul to the Corinthians, Chapter 10, verse 31 instructs, “so whether you eat or drink or whatever you do, do it all for the glory of God.” Apart from the satisfaction of hunger and thirst, man uses food and drink to derive a psychological satisfaction by establishing a spiritual connection with God who is the ultimate Food Provider.
In all religious traditions and cultures of this world, food is associated with God. Food is used in the ritualistic worship of God, food is offered to God, and food is consumed in the name of God. Most religious festivals involve the use of food in celebration of God’s Mercy, Grace and Compassion. Food is traditionally used as the medium for fomenting a spiritual relationship with God.
WHOLE FOOD AND WHOLE UNITY:
Theory of Whole Food and the Prevention of Obesity. “Annam Brahma, RasO Vishnu, Bhokta DevO MaheswaraH” – The Divine Trinity-Brahma, Vishnu, and Shiva define the Indian tradition about Food and Spirituality. Lord Brahma, the Creator symbolizes solid food called Annam, Lord Vishnu the Protector symbolizes liquid food called Rasa, and Lord Shiva the Destroyer symbolizes the Food Consumer called Bhokta. Food and Drink are described as Bhojan, the person who consumes Food and Drink is described as Bhokta. Both Food and the Food Consumer symbolize the Divine Entity. Both man and food are created by God using the powers of Creativity. The nature of man, and the synthesis of food by plants using the process called Photosynthesis involve the use of creative mechanisms and the implantation of supernatural knowledge.
The Indian tradition describes Food and Drink as God and man the consumer of Food and Drink is also described as God. The man must view food as a spiritual substance; spiritual nourishment provided by the LORD God Creator and that devotional attitude towards food would provide nutrition, psychological satisfaction, and social bonding which is complete and wholesome. The creation of Earth, and the Status of Man in nature are the fundamental attributes of the Divine Being and His Divine Powers. The physical, mental, and social well-being of a man is nourished by food that formulates the man’s spiritual relationship with food and the food provider.
WHOLE FOOD AND THE WHOLE PRINCIPLES OF OBESITY PREVENTION:
Theory of Whole Food and the Whole Principles of Obesity Prevention. The Higher-Self can regulate the feeding behavior of the Lower-Self.
1. The man has to eat and drink all his life. 2. The man has a predisposition to obesity as his anatomical structure and physiological functions may not prevent excessive consumption of calories even when the body has satisfactory energy reserve. 3. The man derives nutrients, psychological satisfaction, and develops social bonding by using food. 4. Food when used as a spiritual medium, provides a complete sense of satisfaction and leads to contentment in life. 5. The man has the ability to control his senses, his feelings, and his intellect by acquiring knowledge about food. The Higher-Self can regulate the feeding behavior of the Lower-Self. 6. The man can choose and set limits to his experience of contentment in life. He can set the level of expectation in a manner that the gratification of his desires produces the effect called satiation or satisfaction to defend his physical, mental, social, moral, and spiritual well-being.
Whole Dude – Whole Regulation: How to Regulate the Feeding Behavior? The Principles of Obesity Prevention. The Whole Attitude of Shopping for Whole Food.
Whole Foods, Whole People, and Whole Planet come together in a Wholesome Relationship as God is the Energy Provider, the Original Source of Matter and Energy for Life.
Whole Dude – Whole Foods – Whole Planet – Whole Family – Whole Spirituality: Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods.
Whole Dude – Whole Food – Whole Spirituality: Goddess Annapurna is depicted as The Mother Principle of human creation and existence. The celebration of maternal cytoplasmic inheritance.Whole Dude – Whole Food – Whole Planet – Whole Family – Whole Spirituality: Salutations to Mother Annapurna the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Food.Whole Dude – Whole Food – Whole Planet – Whole Family – Whole Spirituality: Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Food.Whole Dude – Whole Food – Whole Spirituality: What is Food? Human Foods are divided into Classes and the basic nutritional goal is to have a Balanced Diet with items from all of the major Food Groups. The Balanced Diet may or may not provide the experience called ‘SATIATION’Whole Dude – Whole Food – Whole Spirituality: What is Food? Human Foods are divided into Classes and the basic nutritional goal is to have a Balanced Diet with items from all of the major Food Groups. The Balanced Diet may or may not provide the experience called ‘SATIATION’
WHAT IS FOOD?
Whole Dude – Whole Food – Whole Spirituality: What is Food? Human Foods are divided into Classes and the basic nutritional goal is to have a Balanced Diet with items from all of the major Food Groups. The Balanced Diet may or may not provide the experience called ‘SATIATION’
Man is constituted as a Physical being that is made up of about 100 trillion individual living cells that are structurally and functionally differentiated as the tissues, organs and organ systems of the human body. Each living, individual cell is thermodynamically unstable. It means that the living system that is represented by the cell will dissolve into its non-living molecules and elements if not supplied energy from an external source. Food provides those energy-yielding molecules to energy-demanding molecules that constitute the Physical being.
Food is used as a general term to describe substances consumed by man for nourishment. Food is defined as any substance which a living organism can convert into its own living substance from which it grows and develops new tissue, manipulates energy, etc., using a process called ‘metabolism’. The term ‘nutrient’ is explained as a substance that serves as food, or provides nourishment. The term ‘nutrition’ refers to the process of feeding or being nourished. As mentioned earlier, all the tissues and organs of which the human body is composed, consists of building blocks called cells. Every cell contains a spherical body called nucleus and a ground material, living substance, or living matter called ‘protoplasm’. The most striking characteristic of protoplasm is its vital property called ‘Nutrition’. In Human Physiology, the term ‘Nutrition’ is used to describe the ‘power’ which protoplasm has of attracting to itself the materials that provide energy, and the substances for its growth and maintenance from surrounding matter or extracellular environment. Man must feed himself and yet he depends upon the ability of cells to recognize the specific nutrient substances and take action to absorb them and process them for further use.
Whole Dude – Whole Food – Whole Spirituality: What is Food? Human Foods are divided into Classes and the basic nutritional goal is to have a Balanced Diet with items from all of the major Food Groups. The Balanced Diet may or may not provide the experience called ‘SATIATION’
Nutritional Science describes three major functions of food; 1. food generates energy for growth, maintenance and activity, 2. food supplies agents like vitamins and others that are needed to make or to help enzymes which carry out a variety of cellular processes, and 3. food provides the building materials like proteins and amino acids that are used for building cells and tissues of the body. The essential human nutrients are proteins, carbohydrates, fats, minerals, and vitamins. Human body cannot synthesize some of these nutrients and they must be supplied. To make this easy for understanding, human foods are divided into classes and the basic nutritional goal is to have a ‘Balanced Diet’ with items from all of the major Food Groups to perform all the living functions such as the uptake and conversion of nutrients, making, breaking, and repairing of organic molecules, production of energy, and regulation and coordination of various metabolic sequences.
WHAT IS WHOLE FOOD?
Whole Dude – Whole Food – Whole Spirituality: What is Food? Human Foods are divided into Classes and the basic nutritional goal is to have a Balanced Diet with items from all of the major Food Groups. The Balanced Diet may or may not provide the experience called ‘SATIATION’ – This image called ‘MyPlate’ depicts important Food Groups such as Vegetables,Fruits, Grains, Proteins and Dairy. Could we be able to say that these substances together be called as WHOLE FOOD?
The term ‘WHOLE’ is often used to describe something that is entire or complete to signify that it has all the elements or parts constituting the entire amount and it is not broken, damaged, or defective. The term ‘WHOLE’ also means auspicious, healthy, or uninjured and not diseased. We need to define human being as a ‘Whole Person’ to understand the complete entity that exists as man. There are five aspects of ‘Whole Person’:1. Man-the Physical being, 2. Man-the Mental being, 3. Man- the Social being, 4. Man- the Moral being, and 5. Man-the Spiritual being. These five components have to come together to establish the reality of man’s biological existence in the physical world.
Whole Dude – Whole Food – Whole Spirituality: What is Food? Human Foods are divided into Classes and the basic nutritional goal is to have a Balanced Diet with items from all of the major Food Groups. The Balanced Diet may or may not provide the experience called ‘SATIATION’
In the context of ‘Whole Food’, we need to find qualities that fit this description of being ‘Whole’ and its ability to perform all the functions that are attributed to Food. There is a huge growing concern about the substances that are added to food by food industry. The concern involves the use of synthetic or artificial colors, flavors, and preservatives. Food that may contain artificial colors, artificial flavors and chemical preservatives may not promote good health and are even suspected to cause injury or disease. Hence, the concept of ‘Whole Food’ demands the exclusion of such artificial colors and flavors and all synthetic preservatives from the food products used by man for his nutrition. Even when chemicals are not added to food, there is a concern about chemicals like synthetic pesticides, fertilizers and hormones that are used by the food and agriculture industry. It calls for understanding the term called ‘Natural Food’. To be called ‘natural’, food must not be exposed or tainted by chemicals that are not ‘naturally’ present in the substances that are consumed as Food. This concern is often reflected in the demand for ‘Organic Food’ that calls for the exclusion of synthetic pesticides, chemical fertilizers, and growth hormones in the production of food. Apart from these considerations, the use of additives to change the taste, texture, and appearance of food have caused several health-related concerns. Some of them relate to the use of artificial sweeteners, and the use of partially hydrogenated oils. To qualify as ‘Whole Food’, it may require the exclusion of artificial sweeteners and the so-called ‘transfats’ from food. This concern is also extended to genetically modified organisms or GMOs that have become common. The genetically modified trait may impart some benefit to the substance and yet it may not qualify to be described as ‘Whole Food’.
Whole Food – Whole Satisfaction:
WholeDude – WholeDesigner – Phytochemistry: Quinoa seeds are Gluten-Free. It is also Cholesterol-free, low-fat, and high in protein. Throughout the ages many foods have been considered sexual stimulants. Quinoa has a special reason to be recognized as an Aphrodisiac, a chemical agent that can enhance sexual performance. Such a claim can be based upon the study of Polyamines found in its leaves and seeds.
Man is constituted to exist as a Mental being. Man relates to himself, his physical body with the help of his thoughts and moods. It seems that man often tries to discover his ‘essence’ or true identity not in his physical, living substance, but by knowing his ideas, thoughts, and imagination which describes his physical identity. These mental concepts that relate to identity are always associated with emotional feelings and moods that give meaning to the living condition or living state. Food provides substances to constitute the body and it also affects man’s thoughts and moods. The problems related to man’s feeding behavior will not be eliminated by supplying him what could be defined as ‘Balanced Diet’.
The health problems associated with food consumption and caloric intake seem to persist even when man consumes ‘Balanced Diet’. It calls for further understanding of the functions of Food and we have to define the term ‘Whole Food’ by sharing the ‘Whole Story’ about Food and its role in human life. There are two important aspects of Food that are not taken into consideration by Nutritional Science. The Law may require that food products that are sold by retail food stores or grocery stores must provide adequate ‘Nutritional Information’. The products are labeled to provide information about the ingredients, allergens, and nutritional facts to help the consumer of food to make an informed choice about the food that is consumed. Such nutritional choices are helpful and yet there is a problem about the Food. There are two roles performed by Food and the concept of ‘Whole Food’ may have to give recognition to the role of Food apart from its function as the supply of nutrients. Food has to provide Satiation or the experience of mental contentment or psychological satisfaction from its consumption.
Whole Food – Whole Community:
Whole Dude – Whole Food – Whole Spirituality: Man is the natural host of trillions of microbes. It adds a new dimension to the social aspects of man’s existence in the natural world
Man is constituted to exist as a Social being. Man’s growth and development demands social support. Man as a biological living entity could only be described as an association of trillions of individual cells. At the same time, there are about 10 times 100 trillion microbes that inhabit the human gastrointestinal tract. Man is a natural host and there is a mutually beneficial relationship between man the host, and the microbes that reside in his body. During the entire course of his life, man shares his food and drink with the guests who have taken residence in his body. These guests perform the function of an internal organ system and are important for man’s health and well-being. Man will always exist as a member of a Biotic or Biological community without any chance of true independence. This understanding is promoting the consumption of foods that are popularly termed as ‘PROBIOTIC’. Man to support his health and well-being has to consume some living organisms on a regular basis to replenish the microbes that are lost due to excretion.
Whole Dude – Whole Food – Whole Spirituality: What is Food? Human Foods are divided into Classes and the basic nutritional goal is to have a Balanced Diet with items from all of the major Food Groups. The Balanced Diet may or may not provide the experience called ‘SATIATION’
Food plays a vital role in the development, and the maintenance of social interactions, and social relationships.Food-directed activities of man often need social situations and social bonding. Food has the intrinsic ability to nurture a relationship between the provider of the food and the food consumer. At the same time, there is a direct emotional relationship between man and the Food he consumes. Man derives emotional satisfaction called ‘Satiation’ when he consumes Food. It contributes to satisfaction or a sense of mental contentment to shape his living experience. Man lives to experience satisfaction or mental contentment by gratifying his desires or cravings. Food craving is very important part of man’s life and biological existence. Balanced Diet may or may not provide the psychological contentment that man wants to derive by consuming Food. Such satisfaction demands social bonding between man and the food and between man and his provider of food. Hence, we have to develop our understanding of Food as a medium or as a substance that has the potency to develop and form relationships, association, connection, and bonding between man and his social community and environment in which man exists, and by the consumption of ‘Whole Food’ man may find ‘Whole Satisfaction’ in his living experience.
Food = Energy = Life = Whole Ecology:
Whole Dude – Whole Food – Whole Planet – Whole Family – Whole Spirituality : Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Food.Whole Dude – Whole Food – Whole Life -Whole Spirituality: Food is the medium through which interrelatedness, interdependence, and the interconnectedness of living organisms is expressed.
Man is constituted to exist as a Spiritual being. The term Spiritual refers to relationships that are based upon feelings of sympathy and understanding. Man has to define the spiritual basis of his relationship with the rest of the biological community and the physical environment that is common to all of them. Ecology is the Science that is concerned with the relation between organisms and their environment. ‘Food Chain’ in Ecology describes the sequence of transfers of matter and energy from organism to organism in the form of food. Food is the medium through which interrelatedness, interdependence, and the interconnectedness of organisms that are members of an Ecological System is expressed. A balanced growth of organisms that are connected in an Ecosystem demands the concept of ‘Sustainable Development’. Natural resources have to be used wisely to sustain the qualities of environment that support living systems.
Man needs food for his nourishment and to find this nourishment, man may have to stop environmental pollution and degradation that may upset the delicate Ecological Balance that operates in Nature. The manner in which man acquires energy-yielding molecules from his environment will define man’s definition of Food.
Whole Food – Whole Morality:
Whole Dude – Whole Food – Whole Planet – Whole Family – Whole Spirituality: Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Food.
Man is constituted to exist as a Moral Being. Man is intrinsically endowed with a nature that displays the ability called discernment. Man has the ability to choose right conduct and right behavior as he has the ability to discern right from wrong, and distinguish good from bad. This human nature called discernment is related to the nature of the living substance or living matter called protoplasm. I have described its vital property called the Power of Nutrition. It uses this power with a sense of discernment. Protoplasm while attracting substances found in its external environment, it uses a very selective uptake process. Some substances are accepted and tolerated and some are rejected. It expresses intolerance to the presence of certain substances and its response may cause a severe and sometimes life-threatening allergic reaction.
Man has no ability to consume all substances as Food. Man has to know about good and bad food choices, and man has to know as to which food is right and as to which food is wrong. Human beings acting individually and collectively have developed ‘Food Culture’ and Food Traditions to express their moral and ethical principles in all of their food-directed activities and behavior. In recent times, these concerns have developed into ideas such as ‘FAIR-TRADE’, ‘WHOLE-TRADE’ and ‘ECO-TRADE’. There is a growing genuine moral and ethical concern to support the living conditions of people and communities involved in growing Food. There is a growing interest to consume Food that is called ‘LOCAL’; food that is grown or manufactured in the local communities. Man must consume Food for his living and he may have to do it in a morally and ethically responsible manner. These concerns have generated the demand for ethical and compassionate treatment of all animals used as Food for human consumption. Food and Agriculture Industry are developing standards for Compassionate Treatment of Animals. The concept of ‘Whole Food’ would include the moral and ethical principles that man would apply to define his food-related behavior.
Whole Food – Whole Spirituality:
Whole Dude – Whole Food – Whole Planet – Whole Family – Whole Spirituality: Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Food.
Food is defined as any substance which a living organism can convert into its own living substance or living matter called protoplasm, the physical basis of Life. This substance could be viewed as a spiritual substance as it has the potency to formulate functional harmony and mutually beneficial relationship among the cells, tissues, and organ systems that grow and develop using the energy and organic molecules synthesized by protoplasm. The concept of ‘Whole Food’ will naturally include the concept of Food as a Whole Spiritual Substance that must be treated with respect and devotion. Such an attitude of respect and devotion would help man to use Food as a Spiritual Medium to establish a Connection, a Relationship, an Association, a Partnership, and Bonding between the Food Consumer and the Divine Providence.
Whole Food – Whole Life:
Whole Dude – Whole Food – Whole Planet – Whole Family – Whole Spirituality: Salutations to Mother Annapurna. The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Food.Whole Dude – Whole Food – Whole Spirituality: What is Food? Human Foods are divided into Classes and the basic nutritional goal is to have a Balanced Diet with items from all of the major Food Groups. The Balanced Diet may or may not provide the experience called ‘SATIATION’
I define the term ‘Whole Food’ as follows taking into consideration the five aspects of the role of Food in supporting the biological existence of man in his community, and environment as no man is truly capable of independent existence that excludes the social community and the physical environment in which he exists:
1. Whole Food provides the nutritional substances for the Physical well-being of man and supports his living functions.
2. Whole Food provides the satisfaction, the mental contentment that man needs to support his Mental well-being.
3. Whole Food provides the stimulus for social relationships and social bonding that man needs to support his Social well-being.
4. Whole Food provides the ability to man to express his moral and ethical principles to support his Moral well-being.
5. Whole Food provides the Spiritual basis for man’s relationship with Divine Providence to support the Spiritual well-being of man.
Whole Dude – Whole Food – Whole Spirituality
Whole Food is the nutritional substance that supports man’s Physical, Mental, Social, Moral, and Spiritual well-being. These five components of well-being are important to have the experience of Peace, Harmony, and Tranquility in human Life. There is no Joy in Life and there is no Happiness in Mind, and there will be no Love in Heart until man finds Peace, Harmony, and Tranquility in the Living Experience. I say that, Whole Food gives man the experience of Whole Life; a Life of Satisfaction, Contentment, Happiness, and Joy.
Whole Dude – Whole Food – Whole Planet – Whole Family – Whole Spirituality: The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Foods.
I say, I Love Whole Food and what do you want to say? Kindly share your thoughts and views about the concept of ‘Whole Food’.
Whole Dude – Whole Food – Whole Planet – Whole Family – Whole Spirituality: The name Annapurna is the Original Source of Whole or Purna Concept (Always Full, Complete and Perfect). My mother’s name is the equivalent of Whole Food.
The Living SpiritThe Rudi-Grant Connection is derived from the Service in Army Medical Corps.Whole Dude – Whole Dispassion: Can You Drink the Cup I Drink?
The Cap Badges and the Insignia of the British Royal Medical Corps and the Indian Army Medical Corps reveal the Rudi-Grant Connection. The Indian Army Medical Corps was created from the British Royal Army Medical Corps.
Whole Dude – Whole Dispassion: The Rudi-Grant Connection studies the reality of existence without optimism or pessimism
In 1965, while I was a student of Human Anatomy at Kurnool Medical College, I had the opportunity to know about Dr. J. C. B. Grant (1886-1973), the author of Grant’s Atlas of Anatomy. The 5th Edition of his Atlas was published in 1962 and was available in India in our Medical College Library.
Born in Loanhead (south of Edinburgh) in 1886, Grant studied medicine at the University of Edinburgh Medical School and graduated with an M.B., Ch.B. degree in 1908. While at Edinburgh, he worked under the renowned anatomist Daniel John Cunningham. Grant became a decorated serviceman of the Royal Army Medical Corps during the First World War before moving to Canada. He established himself as an ‘anatomist extraordinary’ at the University of Toronto, publishing three textbooks that form the basis of Grant’s Anatomy. The textbooks are still used in anatomy classes today, and made unforgettable memories for those who found themselves in his classes nearly a century ago. One of Grant’s many accomplishments was establishing a division of histology within the department.
Whole Dude – Whole Dispassion: The Rudi-Grant Connection studies the reality of existence without optimism or pessimism
As a medical student, I used Grant’s Atlas of Anatomy, the seminal work of Scottish-born Dr. John Charles Boileau Grant, who would become the chair of Anatomy at the University of Toronto in 1930 and retired in 1965.
Students continue to use Grant’s textbooks today, and for the more artistic anatomist there’s even a Grant’s Anatomy Coloring Book, published in 2018.
Whole Dude – Whole Dispassion: The Rudi-Grant Connection studies the reality of existence without optimism or pessimism
At the University of Toronto, Dr.McMurrich, Chair of Anatomy was succeeded as chairman in 1930 by Dr. John Charles Boileau Grant. Dr. Grant wrote three text books, of which “An Atlas of Anatomy” (published in 1943) rapidly gained international prominence and is still, one of the most widely used anatomical atlases in the world. It is now known as “Grant’s Atlas of Anatomy” and is in its tenth edition. The atlas was based on a series of elegant dissections done either by Grant or by others under his supervision. Many of these dissections are currently housed in Grant’s Museum at the University of Toronto.
The Rudi-Grant Connection is about knowing the man, the building blocks and the structural units and organization of the human body. To defend the human existence, the Rudi-Grant Connection lays the emphasis on knowing the person who is at risk apart from knowing the agent posing the risk.
THE IDENTITY OF MULTICELLULAR HUMAN ORGANISM:
Whole Dude – Whole Dispassion: The Rudi-Grant Connection studies the reality of existence without optimism or pessimism. Dr John Daniel Cunningham (b. April 15, 1850, d. July 23, 1909), Scottish physician and professor of Anatomy. Cunningham’s Manual of Practical Anatomy has provided me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems.
Daniel John Cunningham was born on 15 April 1850 in Scotland. After his initial schooling at his home town, Crieff, he took up the study of medicine at the University of Edinburgh and passed with honours. He is best known for the excellent series of dissection manuals, namely Cunningham’s Dissection Manuals. Cunningham’s Manual of Practical Anatomy has provided me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems.
Whole Dude – Whole Dispassion: The Rudi-Grant Connection studies the reality of existence without optimism or pessimism. Dr John Daniel Cunningham (b. April 15, 1850, d. July 23, 1909), Scottish physician and professor of Anatomy. Cunningham’s Manual of Practical Anatomy has provided me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems.Whole Dude – Whole Dispassion: The Rudi-Grant Connection studies the reality of existence without optimism or pessimism. Dr John Daniel Cunningham (b. April 15, 1850, d. July 23, 1909), Scottish physician and professor of Anatomy. Cunningham’s Manual of Practical Anatomy has provided me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems.Whole Dude – Whole Dispassion: The Rudi-Grant Connection studies the reality of existence without optimism or pessimism. Dr John Daniel Cunningham (b. April 15, 1850, d. July 23, 1909), Scottish physician and professor of Anatomy. Cunningham’s Manual of Practical Anatomy has provided me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems.
I learned about the human body while dissecting the body in a systematic manner. The Manual of Practical Anatomy which guides us through this entire process was published in England. The author Dr. Daniel John Cunningham prepared the Manual while dissecting cadavers of British or Irish citizens. He had never encountered cadavers of Indian citizens. At Kurnool Medical College, Kurnool, Andhra Pradesh, India, where I was a student, the Department of Anatomy obtains dead bodies from Government General Hospital Kurnool and most of the deceased are the poor, illiterate, and uneducated people of that region. None of the deceased had the chance to know this man called Cunningham and Cunningham had no knowledge about the existence of these people who arrive on our dissection tables. But, as the dissection of the human body proceeds, inch, by inch, we recognize the anatomical parts as described by Cunningham. The manual also lists some anatomical variations and we very often exchange information between various dissection tables and recognize the variations mentioned. The dissections also involve slicing the organs and studying them, both macroscopically, and microscopically. We did not miss any part of the human body. So what is the Identity of this Human person or Human subject? How does the living Human organism maintain its Identity and Individuality? Apart from the Cultural Traditions of India, several Schools of Religious Thought claim that the Human Individual and its Identity is represented by Human Soul. Where does this soul exist in the human body? What is the location if the soul is present in the living person? Does man have a soul?How does the human organism acquires Knowledge about its own structures and the functions they perform?
Half Full or Half Empty is not the Right Question – Can You Drink the Cup I Drink?
Whole Dude – Whole Dispassion: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
Excerpt: When I drink from the ‘Cup of my Life’; What I truly experience from my life, the reality of my condition is more important than my attitude towards existence. The man has no hope to find happiness until and unless he renounces all desires including the desire to find happiness. The man has no choice other than that of living in the moment without concern for either pessimism or optimism. The attitude of dispassion automatically excludes both pessimism and optimism.
Whole Dude – Whole Dispassion: Half Full or Half Empty? What is the real Question? Can You Drink the Cup I Drink?
HALF FULL OR HALF EMPTY? IS THAT REALLY IMPORTANT?
Whole Dude – Whole Dispassion: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
I drank from that cup. Now, the cup could be described as half full or half empty. Is that really important? The cup that I drink from gives me pain and I experience suffering. What would be the right question if I have to drink from that cup? What I truly experience from my life, the reality of my condition is more important than my attitude towards my existence. The issue is not about optimism or pessimism. I need to focus on knowing the reality and I need to face the reality about what I experience when I drink from that Cup of my Life.
IS IT POSSIBLE FOR THIS CUP TO BE TAKEN AWAY FROM ME ?
Whole Dude – Whole Dispassion: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
I would answer this question from a reading from The New Testament of The Holy Bible. I would like to quote verses 36 to 44, chapter 26, The Gospel According to Matthew.
Whole Dude – Whole Dispassion: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
36. Then Jesus came with His disciples to a place called Gethsemane and said to them, “Sit here while I go and pray over there.”
Whole Dude – Whole Dispassion: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
37. And He took with Him Peter and the two sons of Zebedee, and He began to be sorrowful and deeply distressed.
Whole Dude – Whole Dispassion: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
38. Then He said to them, “My soul is exceedingly sorrowful, even to death. Stay here and watch with Me.”
Whole Dude – Whole Dispassion: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
39. He went a little farther and fell on His face, and prayed, saying, “O My Father, if it is possible let this cup pass from Me; nevertheless not as I will, but as You will.”
Whole Dude – Whole Dispassion: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
40. Then He came to the disciples and found them sleeping, and said to Peter, “What! Could you not watch with Me one hour?
41.”Watch and pray, lest you enter into temptation. The spirit indeed is willing, but the flesh is weak.”
Whole Dude – Whole Dispassion: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
42. Again, a second time, He went away and prayed, saying, “O My Father, if this cup cannot pass away from Me unless I drink it, may Your will be done.”
43. And He came and found them asleep again, for their eyes were heavy.
Whole Dude – Whole Dispassion: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
44. So He left them, went away again, and prayed the third time, saying the same words.
Whole Dude – Whole Dispassion: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
Jesus had prayed three times, saying the same words. It was not possible for the cup to pass away and Jesus had to drink from the cup.
Whole Dude – Whole Dispassion: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
THE TEACHINGS OF GAUTAMA BUDDHA:
Whole Dude – Whole Dispassion: Lord Gautama Buddha has laid the foundation for understanding Pain and Suffering that is implicit in Human Existence. Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
At age 29, Prince Siddhartha realized that humans are subject to old age, sickness, disability and death. He became aware of the suffering implicit in human existence. Buddha described the nature of reality and Dharma (“true law”) as the Four Noble Truths (1) life is fundamentally disappointment and suffering; (2) suffering is a result of one’s desires for pleasure, power, and continued existence; (3) to stop disappointment and suffering one must stop desiring and (4) the way to stop desiring and thus suffering is the Noble Eightfold Path- right views, intention, speech, conduct, livelihood, effort, mindfulness, and concentration.
From the hymns popularly known as Bhaja Govindam, while I drink from the Cup of my Life, I will keep contemplate on the concept of dispassion:
“KASYA SUKHAM NA KAROTI VIRAGAH”
Whole Dude – Whole Dispassion: Half Full or Half Empty? What is the real Question? Can You Drink the Cup I Drink?
Living in temples or at the foot of trees, sleeping on the ground, wearing deer-skin, renouncing all possessions and their enjoyment – to whom will not dispassion bring happiness?
The verse 19 in Shankaracharya’s Bhaja Govindam questions, “Kasya sukham na karoti viragah?”, which means, “What pleasure cannot be given by dispassion?” It gives all the pleasures because you are so totally living in the moment.
The man has no hope to find happiness until and unless he renounces all desires including the desire to find happiness. The man has no choice other than that of living in the moment without concern for either pessimism or optimism. The attitude of dispassion automatically excludes both pessimism and optimism.
Whole Dude – Whole Dispassion: Half Full or Half Empty? – What is the real Question?Whole Dude – Whole Dispassion: Half Full or Half Empty doesn’t change the reality of the experience.Whole Dude – Whole Dispassion: The Cup of Life holds for me Pain, Humiliation, and Loss of Face. Can You Drink from the Cup I Drink?
Half Full or Half Empty is not the Right Question – Can You Drink the Cup I Drink?
Whole Dude – Whole Question: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
Excerpt: When I drink from the ‘Cup of my Life’; What I truly experience from my life, the reality of my condition is more important than my attitude towards existence. The man has no hope to find happiness until and unless he renounces all desires including the desire to find happiness. The man has no choice other than that of living in the moment without concern for either pessimism or optimism. The attitude of dispassion automatically excludes both pessimism and optimism.
Whole Dude – Whole Question: Half Full or Half Empty? What is the real Question? Can You Drink the Cup I Drink?
HALF FULL OR HALF EMPTY? IS THAT REALLY IMPORTANT?
Whole Dude – Whole Question: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
I drank from that cup. Now, the cup could be described as half full or half empty. Is that really important? The cup that I drink from gives me pain and I experience suffering. What would be the right question if I have to drink from that cup? What I truly experience from my life, the reality of my condition is more important than my attitude towards my existence. The issue is not about optimism or pessimism. I need to focus on knowing the reality and I need to face the reality about what I experience when I drink from that Cup of my Life.
IS IT POSSIBLE FOR THIS CUP TO BE TAKEN AWAY FROM ME ?
Whole Dude – Whole Question: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
I would answer this question from a reading from The New Testament of The Holy Bible. I would like to quote verses 36 to 44, chapter 26, The Gospel According to Matthew.
Whole Dude – Whole Question: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
36. Then Jesus came with His disciples to a place called Gethsemane and said to them, “Sit here while I go and pray over there.”
Whole Dude – Whole Question: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
37. And He took with Him Peter and the two sons of Zebedee, and He began to be sorrowful and deeply distressed.
Whole Dude – Whole Question: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
38. Then He said to them, “My soul is exceedingly sorrowful, even to death. Stay here and watch with Me.”
Whole Dude – Whole Question: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
39. He went a little farther and fell on His face, and prayed, saying, “O My Father, if it is possible let this cup pass from Me; nevertheless not as I will, but as You will.”
Whole Dude – Whole Question: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
40. Then He came to the disciples and found them sleeping, and said to Peter, “What! Could you not watch with Me one hour?
41.”Watch and pray, lest you enter into temptation. The spirit indeed is willing, but the flesh is weak.”
Whole Dude – Whole Question: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
42. Again, a second time, He went away and prayed, saying, “O My Father, if this cup cannot pass away from Me unless I drink it, may Your will be done.”
43. And He came and found them asleep again, for their eyes were heavy.
Whole Dude – Whole Question: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
44. So He left them, went away again, and prayed the third time, saying the same words.
Whole Dude – Whole Question: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
Jesus had prayed three times, saying the same words. It was not possible for the cup to pass away and Jesus had to drink from the cup.
Whole Dude – Whole Question: Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
THE TEACHINGS OF GAUTAMA BUDDHA:
Whole Dude – Whole Question: Lord Gautama Buddha has laid the foundation for understanding Pain and Suffering that is implicit in Human Existence. Half Full or Half Empty? – What is the real Question? Can You Drink the Cup I Drink?
At age 29, Prince Siddhartha realized that humans are subject to old age, sickness, disability and death. He became aware of the suffering implicit in human existence. Buddha described the nature of reality and Dharma (“true law”) as the Four Noble Truths (1) life is fundamentally disappointment and suffering; (2) suffering is a result of one’s desires for pleasure, power, and continued existence; (3) to stop disappointment and suffering one must stop desiring and (4) the way to stop desiring and thus suffering is the Noble Eightfold Path- right views, intention, speech, conduct, livelihood, effort, mindfulness, and concentration.
From the hymns popularly known as Bhaja Govindam, while I drink from the Cup of my Life, I will keep contemplate on the concept of dispassion:
“KASYA SUKHAM NA KAROTI VIRAGAH”
Whole Dude – Whole Question: Half Full or Half Empty? What is the real Question? Can You Drink the Cup I Drink?
Living in temples or at the foot of trees, sleeping on the ground, wearing deer-skin, renouncing all possessions and their enjoyment – to whom will not dispassion bring happiness?
The verse 19 in Shankaracharya’s Bhaja Govindam questions, “Kasya sukham na karoti viragah?”, which means, “What pleasure cannot be given by dispassion?” It gives all the pleasures because you are so totally living in the moment.
The man has no hope to find happiness until and unless he renounces all desires including the desire to find happiness. The man has no choice other than that of living in the moment without concern for either pessimism or optimism. The attitude of dispassion automatically excludes both pessimism and optimism.
Whole Dude – Whole Question: Half Full or Half Empty? – What is the real Question?Whole Dude – Whole Question: Half Full or Half Empty doesn’t change the reality of the experience.
University of Michigan and Michigan Medicine must avoid the social and political constructs of Race and Ethnicity. How does the multicellular human organism verifies its own Identity?
Excerpt: As a research participant, I am investigating the problem of Selection Bias in the Selection Process used by the Research Investigator at University of Michigan. The Selection Bias is inherent in the Selection process for it is gathering information from its human subjects outsides the boundaries of the declared purpose of the Study.
Informed Consent For the Michigan Medicine AHEAD 3-45 Study Screening Procedures
University of Michigan and Michigan Medicine must reject the concept of Race and Ethnicity to describe Asian/Indian Identity
On Tuesday, December 05, 2023, I signed the Informed Consent Form for the AHEAD 3-45 Study Screening Procedures. Reference: UM eResearch ID: HUM00178622; NIA & Eisai Inc. / Protocol Number BAN2401-G000-303
I was informed about an Institutional Review Board (IRB) and was instructed to contact the Study Subject Adviser, Advarra IRB to report my concerns or complaints regarding this research study. I contacted Advarra IRB on December 28 to share my concerns about my exclusion from the study due to the problem of Selection Bias. The following is a copy of that communication sent to the Study Subject Adviser:
Dear Study Subject Adviser,
REFERENCE NUMBER: Pro00041484
As a research participant, I am investigating the problem of Selection Bias in the Selection Process used by the Research Investigator at University of Michigan.
I am informed that I am excluded from further participation in this Study and I want to verify the results of the blood and urine samples I provided on December 05, 2023 to ascertain the fact of my exclusion from the Study is consistent with the Research Protocol for which I have given my written consent.
In any case, I shall hold University of Michigan to its primary responsibility to share the lab test results for it has issued me a Medical Registration Number and informed me about this Hospital Appointment and provided me the assurance that the lab results will be shared with the patient.
Whole Dude – Whole Bias
University of Michigan and Michigan Medicine must reject the concept of Race and Ethnicity to describe Asian/Indian Identity
Selection bias refers to systematic differences between baseline characteristics of the groups that are compared. The unique strength of randomization is that, if successfully accomplished, it prevents selection bias in allocating interventions to participants. Its success in this respect depends on fulfilling several interrelated processes. A rule for allocating interventions to participants must be specified, based on some chance (random) process. We call this sequence generation. Furthermore, steps must be taken to secure strict implementation of that schedule of random assignments by preventing foreknowledge of the forthcoming allocations. This process if often termed allocation concealment, although could more accurately be described as allocation sequence concealment. Thus, one suitable method for assigning interventions would be to use a simple random (and therefore unpredictable) sequence, and to conceal the upcoming allocations from those involved in enrolment into the trial.
University of Michigan and Michigan Medicine must learn that there is no human race called Indian
Excerpt: The Michigan Medicine AHEAD study is examining the efficacy of a medication aimed at preventing Alzheimer’s Disease in individuals at increased risk of developing the disease. The study has, however, faced criticism regarding its focus on years of schooling and its lack of a research protocol to verify the identity and individuality of the human organism. Critics assert that biological processes like the flow of biological information and protein synthesis are not influenced by education level and that individuality should not be tied to factors such as race and ethnicity. The conceptualization of “life as knowledge in action” and that it is an interplay of cellular function and knowledge must be explored.
The following is a copy of the automated response sent by Advarra Adviser (IRB)
From: Advarra Adviser
Thank you for your email. Advarra offices will be closing at 3pm Friday, December 22nd and will be closed through Monday January 1, 2023 for our Holiday Break. Emails sent during this time will be addressed the following business day, Tuesday, January 2nd.
Please note – questions regarding:
*Compensation
*Scheduling
*Test Results
*Study equipment
*Consent form questions
*Enrolling or withdrawing from a studyShould be discussed directly with the research staff. The research staff contact information can be found on the first page of the consent form.
My reply to the automated response sent by Advarra Adviser (IRB):
Thanks for your email. My concern is about the research protocol for which the research scientist obtained my written consent. I am not asking you about the Consent Form Questions. I am asking you to verify the legitimacy of the Research Project to ask the Questions on the Consent Form. Firstly, the AHEAD Study did not disclose that the Study is constructed on the basis of creating a profile information of each research subject. Secondly, the Questions asked have no scientific validity; the information provided has no relevance to the study of this investigational drug. It seems that there is some other agenda is at work to use this research to gather information about research subjects without any concern for the randomization of the selection of research subjects. The Selection Bias is inherent in the Selection process for it is gathering information of its human subjects outsides the boundaries of the declared purpose of the Study.
The AHEAD Study is researching the safety and effectiveness of an investigational medication in people who might be at increased risk for developing memory loss associated with Alzheimer’s Disease. The study is looking for participants age 55-80 years old, who have generally normal memory function in daily life, and who are not being treated for memory problems. For individuals age 55-64 years old, an additional risk factor is required, such as a parent or sibling with Alzheimer’s Disease or previous biomarker testing showing increased risk for developing Alzheimer’s Disease. This study sees participants in Ann Arbor. Contact Lauren Mackenzie at spearsl@med.umich.edu or 734-232-2415.
On Tuesday, December 05, 2023, at the Michigan Clinical Research Unit (MCRU) at the Cardiovascular Center (CVC), I was interviewed for participating in the AHEAD Study and I completed the Stage 1A of the Screening process. I am asked to provide information about the most important occupation of my life, my sexual orientation, my race and ethnicity, my place of birth and the country of origin, the total number of years I spent in the School to register my personal identity for participation in the Medical Research Project. The Research Protocol has not identified the basis for discovering the identity of a multicellular human organism. I can answer the questions I am asked. Do I have the ability to communicate my answers to the cells of my own body and reflect that identity in the living functions they perform to keep me alive?
Racial and Ethnic Differences in Plasma Biomarker Eligibility in a Preclinical Alzheimer’s Disease Trial
Authors: Doris P. Molina-Henry, Rema Raman, Andy Lou, Oliver Langford and others, University of Southern California
Abstract:
Background: In Alzheimer’s disease (AD) trials, differential screen failure due to cognitive and biomarker requirements may contribute to underrepresentation of racially and ethnically minoritized groups. The AHEAD 3‐45 Study (NCT04468659) is an ongoing program testing lecanemab at the stage of preclinical AD that utilizes plasma biomarker prescreening, acquired before cognitive, clinical, and medical history eligibility assessments, to enrich for participants likely to qualify based on amyloid PET eligibility criteria. Methods: We examined the frequency of plasma amyloid biomarker eligibility among racial and ethnic groups in the AHEAD Study. We assigned participants ages 55‐80 to mutually exclusive groups: Hispanic Black (HB), Hispanic White (HW), Non‐Hispanic Asian (NHA), Non‐Hispanic Black (NHB), and Non‐Hispanic White (NHW). We used univariate logistic regression models to explore group differences in screen failure rates as determined by an algorithm that includes the plasma Aβ 42/40 ratio, age, and APOE status. The algorithm indicates an adequately high probability of elevated brain amyloid (>20 centiloids). We further explored whether APOE ε4 status (carrier vs non‐carrier) contributed to group differences. Results Among 4274 participants undergoing plasma screening, 59 (1.4%) were HB, 622 (14.6%) were HW, 74 (1.73%) were NHA, 329 (7.7%) were NHB, and 3190 (74.6%) were NHW. Screen failure rates were 86% for HB, 76% for HW; 80% for NHA; 77% for NHB, and 62% for NHW. Using NHW participants as a reference group, we observed increased odds of screen failure among all other groups (HB OR = 4.0 95% CI 2.0, 9.1; HW OR = 2.0 95% CI 1.6, 2.4; NHA OR = 2.5 95% CI 1.4, 4.5; NHB OR = 2.1, 95% CI 1.6, 2.7). Observed differences were consistent across APOE ε4 carriers and non‐carriers. Conclusion: Differential rates of amyloid eligibility were observed despite the lack of systematic sample bias due to clinical or cognitive requirements observed in previous studies. Potential explanations for these observations include differences in clinical trial access, incidences of elevated amyloid, needed cutoffs for biomarker assays, and confounding due to comorbidities or other unmeasured covariates. This work is supported by a public‐private partnership between Alzheimer’s Clinical Trial Consortium (U24 AG057437) and Eisai.
Disparities by Race and Ethnicity Among Adults Recruited for a Preclinical Alzheimer Disease Trial
Question: Are there racial/ethnic differences associated with recruitment sources and reasons for ineligibility among preclinical Alzheimer disease clinical trial participants?
Findings: In this cross-sectional study of screening data for 5945 participants from a preclinical Alzheimer disease trial, Black, Hispanic, and Asian participants were recruited from local efforts compared with White participants who were recruited from more distributed efforts. Adjusted analysis showed that underrepresented racial/ethnic communities were more likely to be ineligible after the first screening visit.
Meaning: These findings suggest that there are racial and ethnic disparities in preclinical AD clinical trial enrollment that will require a comprehensive approach to study design and recruitment strategies to minimize disproportionate enrollment.
Abstract
Importance: Underrepresentation of many racial/ethnic groups in Alzheimer disease (AD) clinical trials limits generalizability of results and hinders opportunities to examine potential effect modification of candidate treatments.
Whole Dude – Whole Race : Michigan Medicine and University of Michigan reveal their ignorance of the term called Race. There is no Race of People called Indian. However, several Indians, Iranians and Germans celebrate their Aryan Race heritage. I ask Michigan Medicine and University of Michigan to share its educational experience and publish its Theory of Man