Whole Dude is the Whole Person at Whole Foods

Whole Individualism = Molecular Individualism + Law of Individuality

Human Identity and Individuality is defined by the Doctrine of Molecular Individualism

Whole Dude coined the phrase Whole Individualism to discover Man by a study of the building blocks, the structural units and organization of the human body. To defend human existence, Whole Individualism lays the emphasis on knowing the person who is at risk apart from knowing the agent posing the risk.
Whole Dude coined the phrase Whole Individualism to discover Man by a study of the building blocks, the structural units and organization of the human body. To defend human existence, Whole Individualism lays the emphasis on knowing the person who is at risk apart from knowing the agent posing the risk.

In 1965, while Whole Dude was a student of Human Anatomy at Kurnool Medical College, they had the opportunity to know Dr. J. C. B. Grant (1886-1973), the author of Grant’s Atlas of Anatomy. The 5th Edition of his Atlas was published in 1962 and was available in India in their Medical College Library.

Born in Loanhead (south of Edinburgh) in 1886, Grant studied medicine at the University of Edinburgh Medical School and graduated with an M.B., Ch.B. degree in 1908. While at Edinburgh, he worked under the renowned anatomist Daniel John Cunningham. Grant became a decorated serviceman of the Royal Army Medical Corps during the First World War before moving to Canada. He established himself as an ‘anatomist extraordinary’ at the University of Toronto, publishing three textbooks that form the basis of Grant’s Anatomy. The textbooks are still used in anatomy classes today, and made unforgettable memories for those who found themselves in his classes nearly a century ago. One of Grant’s many accomplishments was establishing a division of histology within the department.

Whole Dude coined the phrase Whole Individualism to discover Man by a study of the building blocks, the structural units and organization of the human body. To defend human existence, Whole Individualism lays the emphasis on knowing the person who is at risk apart from knowing the agent posing the risk.

As a medical student, Whole Dude used Grant’s Atlas of Anatomy, the seminal work of Scottish-born Dr. John Charles Boileau Grant, who would become the chair of Anatomy at the University of Toronto in 1930 and retired in 1965.

John Charles Boileau Grant (1886–1973)

Dr. J C B Grant. Whole Dude coined the phrase Whole Individualism to discover Man by a study of the building blocks, the structural units and organization of the human body. To defend human existence, Whole Individualism lays the emphasis on knowing the person who is at risk apart from knowing the agent posing the risk.

The Grant’s Atlas of Anatomy (1943) is used to train thousands of medical students around the world. Grant came to University of Toronto’s Faculty of Medicine from University of Manitoba (and previously Edinburgh), and was Chair of the Department of Anatomy there from 1930 to 1965. Although he is best known for this famous atlas, his research and teaching also included biological anthropology, as evidenced by such work as Anthropometry of the Cree and Saulteaux Indians in Northeastern Manitoba (Archaeological Survey of Canada 1929). The human skeletal collection he formed, the “J.C.B. Grant Collection,” is still a core collection for human osteology in the Department of Anthropology at University of Toronto. He is also remembered in the Grant’s Museum at the Medical Sciences Building at the University of Toronto. This museum, with its displays of anatomical specimens, many of which were dissected by Grant himself, continues to be used in an active learning environment by more than 1000 students each year.

Students continue to use Grant’s textbooks today, and for the more artistic anatomist there’s even a Grant’s Anatomy Coloring Book, published in 2018.

Whole Dude coined the phrase Whole Individualism to discover Man by a study of the building blocks, the structural units and organization of the human body. To defend human existence, Whole Individualism lays the emphasis on knowing the person who is at risk apart from knowing the agent posing the risk.

At the University of Toronto, Dr.McMurrich, Chair of Anatomy was succeeded as chairman in 1930 by Dr. John Charles Boileau Grant. Dr. Grant wrote three text books, of which “An Atlas of Anatomy” (published in 1943) rapidly gained international prominence and is still, one of the most widely used anatomical atlases in the world. It is now known as “Grant’s Atlas of Anatomy” and is in its tenth edition. The atlas was based on a series of elegant dissections done either by Grant or by others under his supervision. Many of these dissections are currently housed in Grant’s Museum at the University of Toronto. 

Whole Dude coined the phrase Whole Individualism to discover Man by a study of the building blocks, the structural units and organization of the human body. To defend human existence, Whole Individualism lays the emphasis on knowing the person who is at risk apart from knowing the agent posing the risk.

The Identity of Multicellular Human Organism:

The Doctrine of Molecular Individualism. Dr John Daniel Cunningham (b. April 15, 1850, d. July 23, 1909), Scottish physician and professor of Anatomy. Cunningham’s Manual of Practical Anatomy has provided Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems.

Daniel John Cunningham was born on 15 April 1850 in Scotland. After his initial schooling at his home town, Crieff, he took up the study of medicine at the University of Edinburgh and passed with honours. He is best known for the excellent series of dissection manuals, namely Cunningham’s Dissection Manuals. Cunningham’s Manual of Practical Anatomy has provided Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs, and Organ Systems.

The Doctrine of Molecular Individualism. Dr John Daniel Cunningham (b. April 15, 1850, d. July 23, 1909), Scottish physician and professor of Anatomy. Cunningham’s Manual of Practical Anatomy has provided Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems.
The Doctrine of Molecular Individualism. Dr John Daniel Cunningham (b. April 15, 1850, d. July 23, 1909), Scottish physician and professor of Anatomy. Cunningham’s Manual of Practical Anatomy has provided Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems.
The Doctrine of Molecular Individualism. Dr John Daniel Cunningham (b. April 15, 1850, d. July 23, 1909), Scottish physician and professor of Anatomy. Cunningham’s Manual of Practical Anatomy has provided Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems.

Whole Dude learned about the human body while dissecting the body in a systematic manner. The Manual of Practical Anatomy which guides us through this entire process was published in England. The author Dr. Daniel John Cunningham prepared the Manual while dissecting cadavers of British or Irish citizens. He had never encountered cadavers of Indian citizens. At Kurnool Medical College, Kurnool, Andhra Pradesh, India, where Whole Dude was a student, the Department of Anatomy obtains dead bodies from  Government General Hospital Kurnool and most of the deceased are the poor, and often the illiterate people of that region. None of the deceased had the chance to know this man called Cunningham and Cunningham had no knowledge about the existence of these people who arrive on our dissection tables. But, as the dissection of the human body proceeds, inch, by inch, we recognize the anatomical parts as described by Cunningham. The manual also lists some anatomical variations and we very often exchange information between various dissection tables and recognize the variations mentioned. The dissections also involve slicing the organs and studying them, both macroscopically, and microscopically. We did not miss any part of the human body. So what is the Identity of this Human Person? How does the living Human organism maintains its Identity and Individuality? Apart from the Cultural Traditions of India, several Schools of Religious Thought claim that the Human Individual and its Identity is represented by Human Soul. Where does this soul exist in the human body? What is the location if the soul is present in the living person? Does man have a soul?

The Whole Dude Doctrine of Whole Individualism and Molecular Individualism

TAT ASMI PRABHU - FIFTH MAHAVAKYA - MOLECULAR INDIVIDUALISM. MAN'S EXISTENCE IS DEFENDED BY MOLECULES CALLED ANTIBODIES WHICH CAN RECOGNIZE OR SEPARATE SELF AND NON-SELF PROTEIN MOLECULES.
THE WHOLE DUDE DOCTRINE OF MOLECULAR INDIVIDUALISM. MAN’S EXISTENCE IS DEFENDED BY MOLECULES CALLED ANTIBODIES WHICH CAN RECOGNIZE OR SEPARATE SELF AND NON-SELF PROTEIN MOLECULES.

The man exists in the physical world for his existence is essentially supported by Unity or ‘Eikyata’ with ‘Prabhu’, or LORD God Creator. It is of great importance to note that man’s existence involves use of a creative mechanism that deploys unique molecules that establish man’s physical identity on a molecular basis. Man’s existence is ‘Conditioned’ for he has no choice other than that of existing as an Individual with Individuality. This Individualistic Nature of Existence is defended by Immune System that deploys unique molecules called Antibodies. Man’s existence is defended by a creative mechanism that involves deployment of Antibody molecules that distinguish or separate Self and Non-Self. Modern Science has provided tools to visually examine large molecules and experimentally verify individualistic variations in their behavior. For this reason, we have to know each man as a Specific Individual with Individuality.

TAT ASMI PRABHU - FIFTH MAHAVAKYA - MOLECULAR INDIVIDUALISM. DR STEVEN CHU, US SECRETARY DEPARTMENT OF ENERGY DEMONSTRATED INDIVIDUALISTIC BEHAVIOR OF LARGE MOLECULES SUCH AS DNA.
THE WHOLE DUDE DOCTRINE OF MOLECULAR INDIVIDUALISM. DR STEVEN CHU, U.S. SECRETARY DEPARTMENT OF ENERGY DEMONSTRATED INDIVIDUALISTIC BEHAVIOR OF LARGE MOLECULES SUCH AS DNA.
The Whole Dude Doctrine of Molecular Individualism. Man exists as an Individual with Individuality. This Individualistic Nature of Existence is defended by Immune System that deploys unique molecules called Antibodies.
The Whole Dude Doctrine of Molecular Individualism. Man exists for he is united with Prabhu or LORD God Creator. Man’s existence is defended by a creative mechanism that involves deployment of Antibody molecules that distinguish or separate Self and Non-Self.

Knowing man’s identity and individuality demands understanding of molecules that defend human existence. For example, each antibody molecule bears two identical binding sites consisting of six b-loops.

The Whole Dude Doctrine of Molecular Individualism: At room temperature atoms and molecules in the air move about at breakneck speed. In order for them to be studied, they need to be slowed down or chilled. During the 1980s Steven Chu, Claude Cohen-Tannoudji, and William Phillips developed different methods for this. When atoms come in contact with light particles with fixed energies, photons, their movement is affected as if they had been bumped. With the aid of laser light from different directions and adjustment of the photon’s energy for Doppler effects, the atoms can be cooled to extremely low temperatures and captured in a trap.

Nobel Laureate, Dr. Steven Chu (United States Secretary of Energy), former Professor of Physics and Applied Physics, Stanford University has described that molecules can exhibit a surprising degree of individuality. In experiments that examine the physical behavior of single molecules, Stanford researchers have discovered that identical polymers; long, flexible, spaghetti-like molecules that are found in everything from plastics to living cells;  UNFOLD in a variety of ways even when exposed to the same experimental conditions. Dr. Chu had stated : “We discovered it because we have developed the ability to visualize and manipulate single molecules.” He had further observed that, “Only by looking at individual animals you can get a true sense of  diversity of species.” Dr. Chu researched Biological Physics and Polymer Physics. Dr. Chu’s research in Polymer Physics made use of individual molecules of DNA to study Polymer Dynamics.

We define our identity in the natural world and defend our existence by deploying unique protein molecules. Our genetic code determines the protein molecules that we use. The genetic code is made up of  DNA strands that express Molecular Individualism. It arises from exceedingly small differences in the initial configuration of the polymer.

We define our identity in the natural world and defend our existence by deploying unique protein molecules. Our genetic code determines the protein molecules that we use. The genetic code is made up of  DNA strands that express Molecular Individualism. It arises from exceedingly small differences in the initial configuration of the polymer.

Nobel Prize for Medicine Goes to Cancer Therapy

The Whole Dude Doctrine of Molecular Individualism. The Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’. 2018 Nobel Prize for Medicine. My Thoughts on the Molecular Basis for the Defense of Human Existence.

American James Allison and Japan’s Tasuku Honjo have won the 2018 Nobel Prize in Medicine for a pioneering approach to cancer treatment.

The Nobel committee said the pair’s research — which harnesses the body’s immune system to attack cancer cells — amounted to a “landmark in our fight against cancer.” The approach, known as immune checkpoint theory, had “revolutionized cancer treatment and has fundamentally changed the way we view how cancer can be managed,” the committee said.

Clipped from: https://www.bbc.com/news/health-45704322

The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: 2018 Nobel Prize for Medicine. My Thoughts on the Molecular Basis for the Defense of Human Existence.

Image copyright SPL

Two scientists who discovered how to fight cancer using the body’s immune system have won the 2018 Nobel Prize for physiology or medicine.

The work, by Professor James P Allison from the US and Professor Tasuku Honjo from Japan, has led to treatments for advanced, deadly skin cancer.

Immune checkpoint therapy has revolutionized cancer treatment, said the prize-giving Swedish Academy.

Experts say it has proved to be “strikingly effective”.

Prof Allison, of the University of Texas, and Prof Honjo, of Kyoto University, will share the Nobel prize sum of nine million Swedish kronor – about $1.01 million or 870,000 euros.

Accepting the prize, Tasuku Honjo told reporters: “I want to continue my research … so that this immune therapy will save more cancer patients than ever.”

Prof Allison said: “It’s a great, emotional privilege to meet cancer patients who’ve been successfully treated with immune checkpoint blockade. They are living proof of the power of basic science, of following our urge to learn and to understand how things work.”

Treating the untreatable

Our immune system protects us from disease, but it has built-in safeguards to stop it from attacking our own tissue.


The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: 2018 Nobel Prize for Medicine. My Thoughts on the Molecular Basis for the Defense of Human Existence.

Image copyright. Kyoto University. Image caption. Professor Tasuku Honjo and his team at Kyoto University

Some cancers can take advantage of those “brakes” and dodge the attack too.

Allison and Honjo, now both in their 70s, discovered a way to unleash our immune cells to attack tumors by turning off proteins that put the brakes on.

And that led to the development of new drugs which now offer hope to patients with advanced and previously untreatable cancer.

Immune checkpoint therapy is being used by the NHS to treat people with the most serious form of skin cancer, melanoma.

It doesn’t work for everyone, but for some patients it appears to have worked incredibly well, getting rid of the tumor entirely, even after it had started to spread around the body.

Such remarkable results had never been seen before for patients like these.


The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: 2018 Nobel Prize for Medicine. My Thoughts on the Molecular Basis for the Defense of Human Existence.

Image copyright. Getty Images. Image caption. Professor James P Allison

Doctors have also been using the treatment to help some people with advanced lung cancer.

Prof Charles Swanton, from Cancer Research UK, congratulated the prize winners, saying: “Thanks to this groundbreaking work, our own immune system’s innate power against cancer has been realized and harnessed into treatments that continue to save the lives of patients. For cancers such as advanced melanoma, lung, and kidney, these immune-boosting drugs have transformed the outlook for many patients who had run out of options.

“The booming field of immunotherapy that these discoveries have precipitated is still relatively in its infancy, so it’s exciting to consider how this research will progress in the future and what new opportunities will arise.”

My thoughts on the Molecular Basis for the Defense of Human Existence


The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: 2018 Nobel Prize for Medicine. My Thoughts on the Molecular Basis for the Defense of Human Existence.

The Molecular Basis for the Defense of Human Existence. Man’s Unity with Lord God Creator can be learned from the study of Immunology. Each Antibody molecule bears two identical binding sites consisting of six b-Loops.

My ‘Theory of Man’ describes the Man as a Created Being. Man’s physical existence in the natural world in good health or ill-health always demands Man’s Unity (Sanskrit. Asmi) with Lord God Creator (Sanskrit. Brahman) for Man is constituted as a Spiritual Being. Man, the Rational Being is inclined to investigate the basis for the reality of his own existence. The reasoning for my statements is derived from the study of Immunology.

The Defense of Human Existence

The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: The Study of Immune System helps in understanding the Molecular Basis for the Defense of Human Existence.

THE MOLECULAR BASIS FOR THE DEFENSE OF HUMAN EXISTENCE. NATURE OF HUMAN IDENTITY AND INDIVIDUALITY IS REVEALED BY HUMAN DEFENSE MECHANISMS.

An individual exists in the natural world by his biological abilities to defend his continued existence as an independent entity. This essay explores the physiological aspects of human existence and the defensive mechanisms that sustain this existence and the molecules which define and shape our Individualism. The term immunity describes the natural defensive mechanisms that give an individual the ability to recognize foreign proteins and foreign substances and neutralize or degrade them with or without injury to the individual’s own tissues. Immunology is the branch of science concerned with the body’s response to foreign agents and substances.

The Functions of the Immune System

The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: The Functions of the Immune System relate to the role played by unique protein molecules in the Defense of Human Existence.

THE MOLECULAR BASIS FOR THE DEFENSE OF HUMAN EXISTENCE. ORGANS, CELLS, AND PROTEIN MOLECULES OF IMMUNE SYSTEM REPRESENT A CREATIVE MECHANISM TO OPPOSE, NEUTRALIZE, AND DESTROY FOREIGN INVADERS.

The immune system responds to invasion by the foreign organisms and their toxic products. This immune response is also described as active immunity. In the natural world, an infant is defended by molecules transferred passively across the placenta from the mother’s circulation during the fetal stage of development. The infant after birth may also receive passively protein molecules from mother when breastfed. This passive immunity defends the baby for several months and the baby further survives by developing its own immune system. Another major function of the immune system is the removal of damaged or dying cells. The immune system is also able to recognize and eliminate abnormal or mutant cells that frequently arise within the body. Using a system that is described as immune surveillance, the body recognizes and disposes of such abnormal cells which could result in the incidence of certain types of cancer. The immune system plays a vital role in protecting the body from bacteria, viruses, fungi, and parasites and helps to prevent certain types of cancer.

The immune system is very important and it is also very sensitive. The system’s very ability to recognize foreign substances may often result in undesirable reactions. Millions of people suffer on account of hypersensitivity or allergic reactions to fairly harmless substances present in the environment. Many individuals suffer on account of their sensitivity to proteins found in the foods such as milk, eggs, fish, wheat (gluten), and nuts that we consume. Sometimes, the immune system is misdirected and initiates an immune response against the body’s own cells or tissues producing a condition known as an autoimmune disease. While an immune system could cause some problems, we take full advantage of the system to defend ourselves from serious infectious diseases such as smallpox,polio,rabies, diphtheria, whooping-cough, measles, rubella, mumps, tetanus, typhoid, cholera, tuberculosis, hepatitis B, influenza and others by using vaccines and inoculations. Millions of lives are protected by routine use of vaccines and inoculations which help the body to become resistant to these infectious agents. We also use foreign proteins to protect the lives of people in times of a severe life-threatening crisis. We use blood, plasma, and sera (containing immunoglobulins secreted by animals) with utmost care to tide over an emergency. I used foreign immunoglobulins to treat snakebite victims and tetanus cases. The foreign proteins elicit a minor immune response and the situation is carefully monitored.

By being careless and reckless, and by polluting our food, water, air, and soil with dangerous chemicals, we damage our very sensitive immune system and this is contributing to a higher incidence of immune-related health problems in the population.

Types of Immune Response

The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: Man’s Intelligence, mental work, and mental memory are not the “First Line of Defense.”

The Molecular Basis for the Defense of Human Existence: The Fundamental Basis of Human Existence is not that of Man’s Intelligence, Mental Memory and Mental Functions.

The immune system defends human existence with a variety of cells and by the protein molecules known as immunoglobulins or antibodies produced by the immune function capable cells. The ability to recognize foreignness, specificity of the response, and the memory of the prior immune response are the key characteristics of immune defense. The immune system must be able to recognize the foreign agents and foreign materials in order to locate and destroy them. Specificity means that immunity to one foreign substance or organism does not provide resistance to another type of organism. Memory is the ability of the individual to develop an accelerated, enhanced, and long-lasting immunity after the initial attack by an infectious disease. The memory function described in Immunology should not be confused with the mental faculty called Memory. The body defends itself through two types of mechanisms which work together to protect our existence. 1. Humoral Immunity:- this involves the production of protein molecules described as immunoglobulins or antibodies.2. Cell-mediated Immunity:- It does not involve secretion of antibodies but requires direct physical contact with the foreign substance or agent. It also involves the use of other protein molecules which assist in the defense mechanisms.

Humoral Immunity

The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: The recognition of Self and Non-Self at the molecular level is the fundamental basis for human existence.

THE MOLECULAR BASIS FOR DEFENSE OF HUMAN EXISTENCE: HUMORAL IMMUNITY INVOLVES DEPLOYMENT OF UNIQUE PROTEIN MOLECULES TO COUNTERACT WITH FOREIGN PROTEIN MOLECULES.

The cells known as Lymphocytes or B cells are produced in the bone marrow and circulate in our blood and are distributed to the various lymphoid tissues in the body, such as the lymph nodes, spleen, tonsils, and Peyer’s Patches (Lymphoid Follicles) that line the small intestine. When stimulated by an infectious organism, production of lymphocytes increases and the lymphocytes are carried to the site of infection. Depending upon the site of infection, the lymph nodes of that region often swell up and are found packed with lymphocytes. The B cells produce chemical substances known as antibodies. These are protein molecules which are specifically generated against specific organisms. The foreign substance is described as antigen. The antibodies that are generated recognize their antigens with high affinity and extreme selectivity. The interaction of an antigen with its specific antibody involves only small areas on the antigen’s surface; these areas are known as antigenic determinants. Protein molecules are very potent antigens as they have several antigenic determinants. Many carbohydrates are also antigenic because they have antigenic determinants. The antibodies circulate in the blood. The simplest, most prevalent means by which the immune system defends the body against bacteria and viruses is by a combination of a specific antibody with the antigenic determinants on the surface of the invading organism. This interaction between antibodies and antigens produces an aggregate of cells called as an agglutination. The body has wandering scavenger cells known as Macrophages. The clumps of agglutinated cells are engulfed and digested by the macrophages. Antibodies also bind to toxic molecules given off by invading microorganisms and this reaction produces large, insoluble aggregates known as precipitates. These precipitates are also removed by macrophages. The virus after entering the body survives by its ability to invade or enter cells. Antibodies prevent the ability of the virus to infect cells by covering up and blocking the attachment sites of the virus.

Cell-Mediated Immunity

The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: Immunity and Immune Response involves the deployment of unique protein molecules.

THE MOLECULAR BASIS FOR THE DEFENSE OF HUMAN EXISTENCE: INTERACTION OF CELLS AND UNIQUE PROTEIN MOLECULES OF IMMUNE SYSTEM DEFINES MAN’S IDENTITY ON MOLECULAR BASIS.

There is another distinct type of Lymphocytes known as T lymphocytes or T cells. T cells originate in the THYMUS and become localized in lymphoid organs. The immunity associated with T cells does not involve secretion of antibodies but through their direct contact with their targets or by the effects of secreted molecules known as lymphokines which help other cells to make the direct contact. There are four kinds of T cells. 1. The cytotoxic T cells
or Natural Killer cells or NK cells defend the body by destroying infected, foreign or cancerous cells. The other three kinds of T cells regulate immune responses by secreting messenger proteins known as lymphokines. 2. Helper T cells enable the other T cells and most B cells to perform their functions. The Helper T cells are destroyed by Human Immunodeficiency Virus (HIV) in Acquired Immune Deficiency Syndrome (AIDS) patients resulting in a depressed immune response that allows infection by a variety of microorganisms and the growth of some types of cancerous tumors. AIDS patients are very vulnerable to fatal infections. 3. Suppressor T cells dampen the immune response of the B and T cells. 4. The fourth kind of T cell is involved in certain kinds of hypersensitivity reactions. In a normal healthy individual, there is a balanced ratio of these four kinds of T cells to provide an efficient immune system for defense against all foreign substances. Macrophages and White blood cells known as neutrophils have the ability to engulf and digest particulate matter by the process of phagocytosis. They eliminate many foreign organisms and particulate materials that enter the body. The ability of NK cells to kill or destroy some cancerous or tumor cells is enhanced by two lymphokines known as gamma interferon and interleukin-1. Another lymphokine known as interleukin-2 activates the Lymphokine Activated Killer Cells or LAK cells which also have the ability to kill a variety of human tumor cells. Activated T cells also secrete a lymphokine known as Transfer Factor which is able to cause normal lymphocytes to release lymphokines or otherwise become activated and thus to destroy other cells. Transfer Factor stimulates the lymphocytes to develop normal immunity.

The Cytotoxic T cells destroy other cells by interacting with antigens present on the surfaces of the cell. They are involved in the attacks on tissues and organs grafted or introduced into the body, viral antigens found on infected cells and on chemicals that have entered the body and found attached to cells. T cells are involved in skin reactions resulting from contact with molecules found in poisonous plants like Poison Ivy, Poison Sumac, and Poison Oak.

Organ Transplantation and Cell-Mediated Immunity

The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: Identity and Individuality are determined by unique protein molecules of the human body.

THE MOLECULAR BASIS FOR THE DEFENSE OF HUMAN EXISTENCE: ORGAN TRANSPLANTATION AND IMMUNOLOGY. MOLECULES OF HISTOCOMPATIBILITY LEUKOCYTE ANTIGEN (HLA) SYSTEM

T cells are involved in the rejection of transplanted tissues and organs. The chances of successful organ transplantation are improved by carefully matching the tissue or Histocompatibility Leukocyte Antigens known as the HLA system of the donor with those of the recipient. The protein molecules of the HLA Complex establish the identity of our body, its tissues, and various organs. They work to preserve the identity of the individual and to exclude the introduction or grafting of foreign material into the body. Even after careful matching, and selection of suitable donors, transplanted tissues or organs are usually maintained by using drugs that cause immunosuppression by which the normal immune response of the recipient against the donated organ is prevented.

Biological Existence

A normal, healthy immune system is vital to defend our biological existence. Immunodeficiency diseases, depressed or compromised immune system conditions such as associated with corticosteroid therapy, chemotherapy, radiation therapy, or exposure to certain types of toxic chemicals, and autoimmune diseases impose a heavy burden and threaten our existence. Medical interventions and treatment may help us but the quality of life is invariably compromised. A functioning immune system is important to defend our existence.

Molecular Individualism

The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: Immunology helps in understanding the Molecular Basis for Man’s Identity and Individuality.

The Molecular Basis for the Defense of Human Existence: Man exists as Individual with Individuality as his existence involves defensive mechanisms operated by independent, individual cells, and protein molecules which exhibit Cellular Autonomy. The cell is the lowest common denominator of all life. While the cell is functionally independent or autonomous or self-governing, it displays the abilities characterized by Mutal Assistance, Cooperation, Tolerance, and Functional Subservience to provide some benefit to the Individual who lives in the physical world.

2018 Nobel Prize for Medicine will help us to develop a ‘Theory of Man’ by the study of unique protein molecules that play an important role in the defense of human survival. The Physical Being called Man needs the support of Spirit, Soul, or a Divine Agency to bring Unity between the cells, tissues, organs, and organ systems providing the structural and functional basis for Man’s existence.

The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’. The Doctrine of Individualism. The Man has no choice other than that of existing as an Individual with Individuality. His genome is unique and one of its own kind.

What is human identity? What is human individuality?

The cellular and the molecular basis of human identity and human individuality
The cellular and the molecular basis of human identity and human individuality. Human Identity undergoes changes due to the aging process but the Human Individuality persists unchanged.
The cellular and the molecular basis of human identity and human individuality

In 1965, while I was a student of Human Anatomy at Kurnool Medical College, I had the opportunity to know about Dr. J. C. B. Grant (1886-1973), the author of Grant’s Atlas of Anatomy. The 5th Edition of his Atlas was published in 1962 and was available in India in our Medical College Library.

Born in Loanhead (south of Edinburgh) in 1886, Grant studied medicine at the University of Edinburgh Medical School and graduated with an M.B., Ch.B. degree in 1908. While at Edinburgh, he worked under the renowned anatomist Daniel John Cunningham. Grant became a decorated serviceman of the Royal Army Medical Corps during the First World War before moving to Canada. He established himself as an ‘anatomist extraordinary’ at the University of Toronto, publishing three textbooks that form the basis of Grant’s Anatomy. The textbooks are still used in anatomy classes today, and made unforgettable memories for those who found themselves in his classes nearly a century ago. One of Grant’s many accomplishments was establishing a division of histology within the department.

The cellular and the molecular basis of human identity and human individuality

As a medical student, I used Grant’s Atlas of Anatomy, the seminal work of Scottish-born Dr. John Charles Boileau Grant, who would become the chair of Anatomy at the University of Toronto in 1930 and retired in 1965.

Students continue to use Grant’s textbooks today, and for the more artistic anatomist there’s even a Grant’s Anatomy Coloring Book, published in 2018.

The cellular and the molecular basis of human identity and human individuality

At the University of Toronto, Dr.McMurrich, Chair of Anatomy was succeeded as chairman in 1930 by Dr. John Charles Boileau Grant. Dr. Grant wrote three text books, of which “An Atlas of Anatomy” (published in 1943) rapidly gained international prominence and is still, one of the most widely used anatomical atlases in the world. It is now known as “Grant’s Atlas of Anatomy” and is in its tenth edition. The atlas was based on a series of elegant dissections done either by Grant or by others under his supervision. Many of these dissections are currently housed in Grant’s Museum at the University of Toronto. 

The Rudi-Grant Connection is about knowing the man, the building blocks and the structural units and organization of the human body. To defend the human existence, the Rudi-Grant Connection lays the emphasis on knowing the person who is at risk apart from knowing the agent posing the risk.

THE IDENTITY OF MULTICELLULAR HUMAN ORGANISM:

The cellular and the molecular basis of human identity and human individuality. Cunningham’s Manuals of Practical Anatomy provide me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems

Daniel John Cunningham was born on 15 April 1850 in Scotland. After his initial schooling at his home town, Crieff, he took up the study of medicine at the University of Edinburgh and passed with honours. He is best known for the excellent series of dissection manuals, namely Cunningham’s Dissection Manuals. Cunningham’s Manual of Practical Anatomy has provided me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems.

The cellular and the molecular basis of human identity and human individuality. Cunningham’s Manuals of Practical Anatomy provide me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems
The cellular and the molecular basis of human identity and human individuality. Cunningham’s Manuals of Practical Anatomy provide me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems
The cellular and the molecular basis of human identity and human individuality. Cunningham’s Manuals of Practical Anatomy provide me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems

I learned the truths about the living human body and about Life while dissecting the dead human bodies in a systematic manner. The Manual of Practical Anatomy which guides us through this entire process was published in England. The author Dr. Daniel John Cunningham prepared the Manual while dissecting cadavers of British or Irish citizens. He had never encountered cadavers of Indian citizens. At Kurnool Medical College, Kurnool, Andhra Pradesh, India, where I was a student, the Department of Anatomy obtains dead bodies from  Government General Hospital Kurnool and most of the deceased are the poor, illiterate, and uneducated people of that region. None of the deceased had the chance to know this man called Cunningham and Cunningham had no knowledge about the existence of these people who arrive on our dissection tables. But, as the dissection of the human body proceeds, inch, by inch, we recognize the anatomical parts as described by Cunningham. The manual also lists some anatomical variations and we very often exchange information between various dissection tables and recognize the variations mentioned. The dissections also involve slicing the organs and studying them, both macroscopically, and microscopically. We did not miss any part of the human body.

The cellular and the molecular basis of human identity and human individuality. Cunningham’s Manuals of Practical Anatomy provide me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems
The cellular and the molecular basis of human identity and human individuality. SPIRITUALITY SCIENCE – THE KNOWER – THE KNOWING-SELF: IN THIS IMAGE OF HUMAN BRAIN, THE GREEN PORTION OF BRAIN STEM IS CALLED RETICULAR FORMATION. I AM PROPOSING TO CALL IT AS THE KNOWING-SELF AND IT IS THE “KNOWER” OF THE HUMAN BODY WHICH CONSTANTLY CHANGES ITS MORPHOLOGICAL APPEARANCE UNDER THE INFLUENCE OF TIME CALLED THE AGING PROCESS.

So what is the Identity of this Human person or Human subject who experiences his life using the Sensory Experience such as taste? How does the living Human organism maintain its Identity and Individuality? Apart from the Cultural Traditions of India, several Schools of Religious Thought claim that the Human Individuality and true or real Identity is represented by Human Soul. Where does this soul exist in the human body? What is the location if the soul is present in the living person? Does man have a soul? How does the human organism acquires Knowledge about its own structures and the functions they perform? To know the burdens of Life, I ask my readers to know the reality of man and the nature of his existence.

Human Identity vs Human Individuality:

Human Identity may involve a variety of factors such as facial appearance, age, gender, race, ethnicity, language, religion, culture, nationality, sexual orientation, social and occupational status. Whereas human individuality has to be evaluated by using the markers that the human body uses to recognize its own Self and defends its own existence from threats posed by Non-Self.

The cellular and the molecular basis of human identity and human individuality
The cellular and the molecular basis of human identity and human individuality. Illustration of the anatomy of a female human face
The cellular and the molecular basis of human identity and human individuality
The cellular and the molecular basis of human identity and human individuality
The cellular and the molecular basis of human identity and human individuality. In the final analysis, the human organism is a biotic community of trillions of individual, independent cells.
The cellular and the molecular basis of human identity and human individuality. SPIRITUALITY SCIENCE – HUMAN EVOLUTION: THE MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) IS THE HUMAN LEUKOCYTE ANTIGEN (HLA) GENE CLUSTER ON CHROMOSOME 6. HUMAN ORGANS AND TISSUES CANNOT BE TRANSPLANTED OR GRAFTED INTO THE BODIES OF UNRELATED INDIVIDUALS. HUMAN IDENTITY MUST BE DISCOVERED AT MOLECULAR LEVEL TO ESTABLISH THE AFFINITY BETWEEN TWO HUMAN INDIVIDUALS.
The cellular and the molecular basis of human identity and human individuality

Human Individuality and the Genome

Individuality and the Genome. A COLONY OF GENETICALLY IDENTICAL E. COLI IS ACTUALLY A MOB OF ‘INDIVIDUALS’.

UNDERSTANDING INDIVIDUALITY: 

Individuality and the Genome. Even among simple forms of life, like the common bacterium E. coli, genetics only partly determines what any one organism is like. E. coli expresses its individuality in many ways. All the bacilli above are genetically identical, but the shades show differences in the production of proteins that digest lactose.Credit…Dr. Michael Elowitz

Dr. Michael Elowitz, Physicist at California Institute of Technology has conducted experiments on colonies of genetically identical (Clones) E. coli bacteria under identical experimental conditions and has discovered that the clones behave in different ways which could be viewed as an expression of ‘individuality’.

Individuality and the Genome. The Law of Individuality governs all Individual Living Things.

E. coli bacteria in billions populate our intestines. Typical E. coli bacillus has about 4,000 genes. Human cells have about 20,000 genes. The bacteria have fingerprints of their own and even when they share the exact same genome, they could still be identified as ‘individuals’.

Individuality and the Genome. Dr. Michael Elowitz and Dr. Long Cai are developing a platform through which cells can self-record their lineage and molecular event histories directly into their own DNA as they create new tissues, particularly in the brain. This research will help to address how individual cells in a developing embryo diversify into many distinct cell types, each playing its unique role in the organism.

The key to understanding E. coli’s fingerprints is to recognize that the bacteria are not simple machines. Unlike wires and transistors, E. coli’s molecules are floppy, twitchy and unpredictable. In an electronic device, like a computer or a radio, electrons stream in a steady flow through the machine’s circuits, but the molecules in E. coli jostle and wander. When E. coli begins using a gene to make a protein, it does not produce a smoothly increasing supply. It spurts out the proteins in fits and starts. One clone may produce half a dozen copies of a protein in an hour, while a clone right next to it produces none.

Michael Elowitz, a physicist at Caltech, put these bursts on display in an elegant experiment. He and his colleagues incited E. coli to produce its proteins for feeding on lactose. Dr. Elowitz and his colleagues added extra genes to the bacteria so that when they made lactose-digesting proteins, they also released light.

The bacteria, Dr. Elowitz found, did not produce a uniform glow. They flickered, sometimes brightly, sometimes dimly. And when Dr. Elowitz took a snapshot of the colony, it was not a uniform sea of light. Some microbes were dark at that moment while others shone at full strength.

At the very least, E. coli’s individuality should be a warning to those who would put human nature down to any sort of simple genetic determinism. Living things are more than just programs run by genetic software. Even in minuscule microbes, the same genes and the same genetic network can lead to different fates.

The bacteria have fingerprints of their own and even when they share the same genome, they could still be identified as individuals.

Individuality and the Genome. Man is constituted as a Biotic Community of socially interacting cells and microbes

Humans differ from one another in too many different ways and it is hard to count. The current human population of over six billion could be identified as the same number of individuals. Each human being has an unique genome of his own. There are millions of typographical differences between one genome and another human genome. Even identical twins are not truly identical at all as identical genes in our cells can behave differently. 

Living entities are not like simple machines. When we use a gene to make a protein, the gene may not produce a smoothly increasing supply of that protein. The gene tends to work in fits and starts and spurts out the protein. Identical genes can behave differently as the gene makes protein or remains silent depending upon the ‘Methyl’ groups that cap the DNA strands and function as ‘transducers’. These ‘Methyl’ groups sometimes fall off of DNA or become attached to new spots. Hence genetically identical individuals can have different physical identities in the natural world. The protein molecules that make up living entities, turn them into individuals. 

THE IRRELEVANCE OF EVOLUTION: 

Individuality and the Genome: CHARLES DARWIN’S ORIGIN OF SPECIES (1859) PROPOSES A MECHANISTIC, NONPURPOSIVE ACCOUNT OF EVOLUTION AS THE PRODUCT OF THE NATURAL SELECTION OF RANDOMLY PRODUCED GENETIC MUTATIONS.

In the natural world, all living entities exist as individuals and express their individuality. The Theory of Evolution proposes that a species can descend or arrive to become a new species by changing its genome in a gradual and incremental manner using a mechanism that is described as ‘ natural selection ‘. The mechanism of natural selection operates via a process of random and unguided mutations in the genetic code that changes the genome and eventually produces the ‘biodiversity’ that we witness in the natural world.

Individuality and the Genome. The phenomenon of Diversity must be studied beyond the realm of genes, genetic codes, and genomes. Cytoplasm and its organs must be studied to understand the physiological basis of Diversity

This Theory of Evolution has no relevance to the ultimate identity of each individual member of a given species. This identity is dictated by the interplay between the various components of each individual cell and its interactions with other cells. With the same genomes or different genomes, the living entities can only exist as individuals and they have no other choice. The evolutionary connections are not relevant to this identity. To understand the phenomenon of biodiversity, we will be forced to look at each individual member of each given species. 

THE LAW OF INDIVIDUALITY: 

Individuality and the Genome. The Law of Individuality formulates the phenomenon of Human Individuality.

I propose that the Law of Individuality governs all the living entities and is manifested in various biological phenomena. The genes and the genetic code function in accordance with the Law of Individuality. I would describe Individuality as a Trade Mark. It is the characteristic of a biological entity. Genes and the genetic codes are the tools that an organism uses to express its Individuality. Each organism assembles its own kind of protein molecules to define its identity and to defend its existence in the natural world. 

Individuality and the Genome. The Law of Individuality formulates the phenomenon of Human Individuality.

WHOLE SPIRITUALITY – WHOLE SYNTHESIS

Spiritualism – The New Synthesis:

Dr. Edward Osborne Wilson,American biologist, an expert in the Study of Ants(Myrmecology), former Professor of Zoology, Harvard University, founder of Sociobiology, has studied the genetic basis of the social behavior of all animals including humans. He had presented his theories about the biological basis of Social Behavior in his book, Sociobiology : The New Synthesis(1975). The biological basis of Social Behavior must include the study of the Behavioral Ability of the Living Substance.

Dr. Edward Osborne Wilson is recognized as the world’s leading authority on ants. He is the foremost proponent of Sociobiology, the study of the genetic basis of the social behavior of all animals including humans. In his book, Sociobiology: The New Synthesis (1975) he presents his theories about the biological basis of social behavior. It involves the application of the Theory of Evolution to the study of animal and human social behavior. It holds that the Theory of Evolution by ‘natural selection’ applies to behavior in the same way that it applies to structure and physiological functions. He holds that behavior patterns are genetically determined and are governed by the process of ‘natural selection’. Accordingly, he explains that social behavior relies upon the principle that genes are able to influence behavior and will be selected if the behaviors they encourage contribute ultimately to the reproductive success of the individual carrying those genes. The ‘Darwinian Fitness’ of an organism or a gene is a measure of the ability of that organism or gene to project copies of itself into future generations. Because, ‘natural selection’ would influence genetically controlled behavior, he believes that individuals will tend to behave in ways that maximize their ‘Darwinian Fitness’. However, he attributes 10 percent of human behavior as genetically induced, the rest being attributable to environment.

In my analysis, it could be indeed true that some behavioral abilities depend upon underlying genetic mechanisms which support the neural and hormonal mechanisms that are required in the performance of actions by organisms. Dr. Wilson recognizes the essentially biological principles on which animal societies are based and could apply those principles to human social behavior. One of Dr. Wilson’s most notable theories is that a characteristic such as ‘altruism’ could be genetically based and may have evolved through the process of ‘natural selection’. Dr. Wilson maintains that altruistic behavior is consistent with ‘natural selection’ in that the sacrifice is made to save closely related individuals who share many of the sacrificed organism’s genes.

Altruism and Sociobiology:

Ants, approximately 8,000 species of the Insect family Formicidae ( Order Hymenoptera )are social in habit and live together in organized colonies. Worker ants are maximally ‘altruistic’ and devote their whole lives to caring for the Queen to reproduce, constructing and protecting the nest, foraging for food, and tending the larvae while they are sterile. The worker ants display unselfish concern for the welfare of others and they have no chance to reproduce.

The term ‘altruism’ (French – altruisme) was coined by Auguste Comte, the founder of Positivism and Sociology. It is considered as antithesis to Egoism. Altruism is behavior that benefits others at some cost to the individual displaying altruistic behavior. Social scientists refer to altruism as the behavior of an individual who consciously comes to the aid of another, without expecting anything in return. Such behavior is influenced by empathy, an emotional response that results from being aware of another person’s emotions. In Ethics, altruism is described as a theory of conduct that regards the good of others as the end of moral action. It describes unselfish concern for the welfare of others.

However, biologists view altruism as any behavior that reduces the ‘Darwinian Fitness’ (reproductive success) of the altruist while increasing the fitness of another. It is common for animals to share food, help provide for another’s young, defend others against predators, and give alarm calls when a predator appears. Such animal altruism is common and it does not require psychological abilities and functions like sharing of emotions, feelings, and thoughts. Altruism as a behavior  is not always a psychological function or ability. It is displayed as pure altruism in the social behavior of worker bees, ants, and wasps.

Spiritualism – The New Synthesis:

It must be understood that behavior is a fundamental characteristic of life and of all living entities. All species, whether single-celled protozoans or the largest of mammals possess the capacity to respond to stimuli in their environment. This ability called responsiveness is the fundamental attribute of all kinds and types of behavior.

Psychologists like B.F. Skinner tend to focus on the learned components of behavior and stress the importance of environment and its influence on behavior. Biologists like Konrad Lorenz tend to focus primarily on the analysis of the innate components of behavior. Sociobiologists tend to recognize the role of genes and the influence of environment and describe that  behavioral abilities depend on underlying genetic mechanisms that develop the structures and physiological mechanisms that are important to display a given behavior. It may be noted that both Psychologists and Biologists are describing behavior in the context of social relations and interactions between individual and groups of living organisms. Living things behave in ways to maximize their chances of survival. In the entire animal kingdom, most living organisms display parental or social instincts. All animals display social behavior. There is no animal that is ever completely isolated from some kind of environment that includes members of the same species or other species. Animals form parental societies to care for their offspring. Bacteria come together to live as colonies. Hence, it will be important to recognize social behavior that is displayed by individual living cells.

I define Spiritualism as the capacity or the biological ability of an individual living cell to formulate harmonious relations with others and to participate in or contribute constructively to changes in the social environment. The potency called Spiritualism is reflected in the biological functions of Consciousness and Intelligence.

Red Blood Cells – Altruism – Spiritualism – The New Synthesis: Unlike most cells of the human organism, mature Red Blood Cells do not have nuclei, have no mitochondria, and have no other organelles. The Red Blood Cells cannot divide and reproduce and lead a short life while they exist to support the life and survival of trillions of other cells in the body.

At a cellular level, the social aspect of Consciousness is reflected by the biological abilities of the cell such as  association, cooperation, communication, recognition of other living cells in its immediate environment, and performing actions which have characteristics of functional subservience to provide benefits like survival and reproductive success to other cells. A very good example of Spiritualism is that of altruism displayed by the mature Red Blood Cells of the man. The mature Red Blood Cells have no nuclei and hence cannot divide or reproduce. Each Red Blood Cell has a very limited life span of its own. They sustain their meagre energy needs by a form of anaerobic respiration as they do not have mitochondria like the trillions of other cells of the human body. The Red Blood Cells are passive in nature and they simply exist to provide Oxygen to other cells and tissues, collect Carbon Dioxide while being swept along by the blood stream. Since the mature Red Blood Cells have no nuclei, their behavior is not operated by genes or genetic mechanisms which could be important in their formation, development, and maturation. The social aspects of the Red Blood Cell behavior is related to the spiritual nature of its living substance.

I would ask Biologists to give attention to the nature, functional abilities of the living substance apart from the consideration of genes and genetic mechanisms. It may be very clearly understood that the nucleus, the chromosomes, and the genes have no independent existence of their own and they perform their cellular functions while they derive energy and nutritional support from the living substance or Protoplasm that has the biological abilities of Consciousness, and Intelligence which is reflected in its properties like responsiveness, the power of nutrition, and reproduction.

Spiritualism is the Science of New Synthesis; the New Synthesis that formulates the relationships between Substance, Structure, Function, Heredity of a Living Organism and its Environment, Behavior, and Social Community.

Related articles
Spiritualism – The New Synthesis. The Behavior pf the Red Blood Cell can be described as Altruism. Red Blood Cells are packed with hemoglobin. Each Red Cell contains over 600 million hemoglobin molecules.

WHOLE SPIRITUALITY – WHOLE DOCTRINE

Protoplasm
Protoplasm, the living, corporeal substance, is the source of energy, knowledge, and work that supports the living form that lives and is known. (Photo credit: salimfadhley)

SPIRITUALISM – THE MEDICAL DOCTRINE OF DIALECTICAL SPIRITUALISM :

Georg Wilhelm Friedrich Hegel(b. August. 27, 1770, d. November. 14, 1831),German Idealist Philosopher, author of Phenomenology of Spirit or Phenomenology of Mind(1807), Science of Logic(1812-16), and Encyclopedia of the Philosophical Sciences(1817) and other works and lectures. He developed theories of Ethics, Aesthetics, History, Politics, and Religion. He developed a Dialectical scheme that influenced the development of Existentialism, Marxism, Positivism, and Analytic Philosophy.

Georg Wilhelm Friedrich Hegel influenced most facets of modern philosophy. At the center of the universe, Hegel posited an enveloping absolute Spirit that guides all reality including human reason. His absolute ‘Idealism’ envisages a world-Soul, that develops from, and is known through, a process of change and progress termed as the Hegelian Dialectic. The doctrine of ‘Idealism’ makes the attempt to account for all objects in nature and experience as representations of the mind, and sometimes it assigns to such representations a higher order of existence. According to Hegel, reality is Absolute Mind, Reason, or Spirit which manifests itself in both natural and human history. His famous dictum, “the real is rational and the rational real”, is an expression of the identity of reality and the rational process. Because reality is rational, it acts in accordance with the laws of reasoning. Hegel suggested that understanding the nature of thought will lead to understanding the nature of reality as a whole. Dialectics is a form of logical argumentation that could be applied to diverse fields including thought, nature, and history. Hegel identified dialectic as the tendency of a notion, or idea to pass over into its own negation as the result of conflict between its inherent contradictory aspects. He developed the concept that Mind or Spirit manifested itself in a set of contradictions and oppositions that it ultimately integrated and united without eliminating either pole or reducing one to the other. According to Hegelian principles, one concept or ‘thesis’ inevitably generates its opposite or ‘antithesis’; their conflict or interaction generates a new concept or ‘synthesis’ which in turn becomes the ‘thesis’ of a new triad. Hegel developed a dialectical scheme that emphasized the progress of history and ideas from ‘thesis’ to ‘antithesis’ and then to a higher and richer ‘synthesis’. His main contribution is that of giving a clear view of reality; Reality can only be understood as a totality, “The Truth is the Whole”, and that the attempt to understand the apparently individual and unconnected phenomena of nature, history, and human life through separate categories of thought is utterly mistaken. I would like to endorse his view and submit that Reality must be known as a Whole.

THE MEDICAL DOCTRINE OF DIALECTICAL SPIRITUALISM :

Amoeba proteus and the understanding of Reality as a Whole or the ‘Whole Truth’. To understand the reality of human life, we need to know and understand the Reality of a material substance that is common to all living organisms. This common substance called Protoplasm is found in all living cells including the cells of human brain, an anatomical organ that is associated with thinking,and Mind the seat of thoughts. However, I would ask all of my readers to know and understand Protoplasm, the substance in which thoughts are generated and reside. I give attention to the Spiritual Nature of this substance and divert attention from Mind and Brain.

 Hegel in his book, Phenomenology of Mind or Phenomenology of Spirit has traced the progression of consciousness from sense perception to Absolute Knowledge. In my view, Amoeba proteus is conscious and intelligent. I speak about Spirit or Soul in relation to a material substance called Protoplasm. I would hesitate to equate Mind with Spirit as that would mislead people to think of consciousness and intelligence as the exclusive biological functions of an anatomical organ called brain. At the same time, it must be clearly understood that brain and mind perform their specialized functions using the same living matter or substance that is found inside Amoeba proteus. The fact that brain and mind perform very complex functions should not hide the fact of the true or real nature of Protoplasm. There is inherent conflict in the nature of Protoplasm. It is inherently unstable; the living matter is thermodynamically unstable, and without continuous supply of energy from an external source, it will dissolve into its constituent inorganic molecules and non-living physical elements. This nature of energy dependence and the risk of its dissolution is the ‘thesis’ and it is opposed by its potency and potential to remain immutable, or unchanging, the ‘antithesis’. Protoplasm is unstable and is stable at the same time. It has survived and has continuously lived on the surface of planet Earth for billions of years after having come into existence. We have account of several major and minor extinction events and yet Protoplasm has remained and existed without any apparent change in its properties, characteristics, and functions. Protoplasm has demonstrated the potentiality called Imperishability, indestructibility, Immortality and the ability of Eternal or Everlasting Life. The interaction or conflict between unstable(‘thesis’) and stable(‘antithesis’) nature of Protoplasm has generated a new ‘synthesis’ called Immortality or Everlasting Life. I call this higher state of existence as ‘Dialectical Spiritualism’. Man is a physical, Mortal Being and his body substance is Perishable. Through the process of Dialectical Spiritualism, the conflict and interaction between the unstable and stable nature of Protoplasm which is a Spiritual substance, man progresses towards his goal of becoming a Complete or Whole Spiritual Being and his body substance will exist in its higher state of existence of  Imperishability. The Medical Doctrine of Dialectical Spiritualism proposes the hypothesis of Man’s Immortality or Everlasting Life as a higher state of existence of a mortal or perishable substance that has developed the potentiality and progressed towards its natural goal of Imperishability and indestructibility.

Dr. R. Rudra Narasimham, B.Sc., M.B.B.S.,

Kurnool Medical College, Kurnool, Andhra Pradesh, India,

M.B.B.S.  Class  of  April,  1970.