University of Michigan and Michigan Medicine must reject the concept of Race and Ethnicity to describe Asian/Indian Identity
As a research participant, Whole Dude investigates the problem of Selection Bias in the Selection Process used by the Research Investigator at University of Michigan. The Selection Bias is inherent in the Selection process for it is gathering information of its human subjects outsides the boundaries of the declared purpose of the Study.
The Problem of Selection Bias – Disparities by Race and Ethnicity among adults recruited for a Preclinical Alzheimer’s Disease Trial at Michigan Medicine
Whole Foods-Whole Inspiration-Whole LanguageWhole Foods Arrives in Ann Arbor, September 1993Whole Foods opened its Store in Ann Arbor on September 16, 1993. Whole Foods, Whole People and Whole Planet inspire Whole Dude to invent Whole Phrases: Whole Linguistics – Whole Language. The concept of Whole Cookie and Whole Love. Whole Dude uses the phrase Whole Linguistics to describe three entities; 1. Language User, 2. Language Interpreter and 3. Language Creator. Image Credit: Agenda Publications, Ann Arbor District Library, Issue Dates, September 1993, December 1997 and February 1998.As a research participant, Whole Dude investigates the problem of Selection Bias in the Selection Process used by the Research Investigator at University of Michigan. The Selection Bias is inherent in the Selection process for it is gathering information of its human subjects outsides the boundaries of the declared purpose of the Study.
Excerpt: As a research participant, Whole Dude investigates the problem of Selection Bias in the Selection Process used by the Research Investigator at University of Michigan. The Selection Bias is inherent in the Selection process for it is gathering information of its human subjects outsides the boundaries of the declared purpose of the Study.
Informed Consent For the Michigan Medicine AHEAD 3-45 Study Screening Procedures
As a research participant, Whole Dude investigates the problem of Selection Bias in the Selection Process used by the Research Investigator at University of Michigan. The Selection Bias is inherent in the Selection process for it is gathering information of its human subjects outsides the boundaries of the declared purpose of the Study.
On Tuesday, December 05, 2023, Whole Dude signed the Informed Consent Form for the AHEAD 3-45 Study Screening Procedures. Reference: UM eResearch ID: HUM00178622; NIA & Eisai Inc. / Protocol Number BAN2401-G000-303
I was informed about an Institutional Review Board (IRB) and was instructed to contact the Study Subject Adviser, Advarra IRB to report my concerns or complaints regarding this research study. I contacted Advarra IRB on December 28 to share my concerns about my exclusion from the study due to the problem of Selection Bias. The following is a copy of that communication sent to the Study Subject Adviser:
Dear Study Subject Adviser,
REFERENCE NUMBER: Pro00041484
As a research participant, I am investigating the problem of Selection Bias in the Selection Process used by the Research Investigator at University of Michigan.
I am informed that I am excluded from further participation in this Study and I want to verify the results of the blood and urine samples I provided on December 05, 2023 to ascertain the fact of my exclusion from the Study is consistent with the Research Protocol for which I have given my written consent.
In any case, I shall hold University of Michigan to its primary responsibility to share the lab test results for it has issued me a Medical Registration Number and informed me about this Hospital Appointment and provided me the assurance that the lab results will be shared with the patient.
Whole Dude investigates Whole Bias at Michigan Medicine
As a research participant, Whole Dude investigates the problem of Selection Bias in the Selection Process used by the Research Investigator at University of Michigan. The Selection Bias is inherent in the Selection process for it is gathering information of its human subjects outsides the boundaries of the declared purpose of the Study.
University of Michigan and Michigan Medicine must reject the concept of Race and Ethnicity to describe Asian/Indian Identity
Selection bias refers to systematic differences between baseline characteristics of the groups that are compared. The unique strength of randomization is that, if successfully accomplished, it prevents selection bias in allocating interventions to participants. Its success in this respect depends on fulfilling several interrelated processes. A rule for allocating interventions to participants must be specified, based on some chance (random) process. We call this sequence generation. Furthermore, steps must be taken to secure strict implementation of that schedule of random assignments by preventing foreknowledge of the forthcoming allocations. This process if often termed allocation concealment, although could more accurately be described as allocation sequence concealment. Thus, one suitable method for assigning interventions would be to use a simple random (and therefore unpredictable) sequence, and to conceal the upcoming allocations from those involved in enrolment into the trial.
University of Michigan and Michigan Medicine must learn that there is no human race called Indian
As a research participant, Whole Dude investigates the problem of Selection Bias in the Selection Process used by the Research Investigator at University of Michigan. The Selection Bias is inherent in the Selection process for it is gathering information of its human subjects outsides the boundaries of the declared purpose of the Study.
Excerpt: The Michigan Medicine AHEAD study is examining the efficacy of a medication aimed at preventing Alzheimer’s Disease in individuals at increased risk of developing the disease. The study has, however, faced criticism regarding its focus on years of schooling and its lack of a research protocol to verify the identity and individuality of the human organism. Critics assert that biological processes like the flow of biological information and protein synthesis are not influenced by education level and that individuality should not be tied to factors such as race and ethnicity. The conceptualization of “life as knowledge in action” and that it is an interplay of cellular function and knowledge must be explored.
The following is a copy of the automated response sent by Advarra Adviser (IRB)
From: Advarra Adviser
Thank you for your email. Advarra offices will be closing at 3pm Friday, December 22nd and will be closed through Monday January 1, 2023 for our Holiday Break. Emails sent during this time will be addressed the following business day, Tuesday, January 2nd.
Please note – questions regarding:
*Compensation
*Scheduling
*Test Results
*Study equipment
*Consent form questions
*Enrolling or withdrawing from a studyShould be discussed directly with the research staff. The research staff contact information can be found on the first page of the consent form.
My reply to the automated response sent by Advarra Adviser (IRB):
Thanks for your email. My concern is about the research protocol for which the research scientist obtained my written consent. I am not asking you about the Consent Form Questions. I am asking you to verify the legitimacy of the Research Project to ask the Questions on the Consent Form. Firstly, the AHEAD Study did not disclose that the Study is constructed on the basis of creating a profile information of each research subject. Secondly, the Questions asked have no scientific validity; the information provided has no relevance to the study of this investigational drug. It seems that there is some other agenda is at work to use this research to gather information about research subjects without any concern for the randomization of the selection of research subjects.
The Selection Bias is inherent in the Selection process for it is gathering information of its human subjects outsides the boundaries of the declared purpose of the Study.
The AHEAD Study is researching the safety and effectiveness of an investigational medication in people who might be at increased risk for developing memory loss associated with Alzheimer’s Disease. The study is looking for participants age 55-80 years old, who have generally normal memory function in daily life, and who are not being treated for memory problems. For individuals age 55-64 years old, an additional risk factor is required, such as a parent or sibling with Alzheimer’s Disease or previous biomarker testing showing increased risk for developing Alzheimer’s Disease. This study sees participants in Ann Arbor. Contact Lauren Mackenzie at spearsl@med.umich.edu or 734-232-2415.
On Tuesday, December 05, 2023, at the Michigan Clinical Research Unit (MCRU) at the Cardiovascular Center (CVC), I was interviewed for participating in the AHEAD Study and I completed the Stage 1A of the Screening process. I am asked to provide information about the most important occupation of my life, my sexual orientation, my race and ethnicity, my place of birth and the country of origin, the total number of years I spent in the School to register my personal identity for participation in the Medical Research Project. The Research Protocol has not identified the basis for discovering the identity of a multicellular human organism. I can answer the questions I am asked. Do I have the ability to communicate my answers to the cells of my own body and reflect that identity in the living functions they perform to keep me alive?
Racial and Ethnic Differences in Plasma Biomarker Eligibility in a Preclinical Alzheimer’s Disease Trial
Authors: Doris P. Molina-Henry, Rema Raman, Andy Lou, Oliver Langford and others, University of Southern California
Abstract:
Background: In Alzheimer’s disease (AD) trials, differential screen failure due to cognitive and biomarker requirements may contribute to underrepresentation of racially and ethnically minoritized groups. The AHEAD 3‐45 Study (NCT04468659) is an ongoing program testing lecanemab at the stage of preclinical AD that utilizes plasma biomarker prescreening, acquired before cognitive, clinical, and medical history eligibility assessments, to enrich for participants likely to qualify based on amyloid PET eligibility criteria. Methods: We examined the frequency of plasma amyloid biomarker eligibility among racial and ethnic groups in the AHEAD Study. We assigned participants ages 55‐80 to mutually exclusive groups: Hispanic Black (HB), Hispanic White (HW), Non‐Hispanic Asian (NHA), Non‐Hispanic Black (NHB), and Non‐Hispanic White (NHW). We used univariate logistic regression models to explore group differences in screen failure rates as determined by an algorithm that includes the plasma Aβ 42/40 ratio, age, and APOE status. The algorithm indicates an adequately high probability of elevated brain amyloid (>20 centiloids). We further explored whether APOE ε4 status (carrier vs non‐carrier) contributed to group differences. Results Among 4274 participants undergoing plasma screening, 59 (1.4%) were HB, 622 (14.6%) were HW, 74 (1.73%) were NHA, 329 (7.7%) were NHB, and 3190 (74.6%) were NHW. Screen failure rates were 86% for HB, 76% for HW; 80% for NHA; 77% for NHB, and 62% for NHW. Using NHW participants as a reference group, we observed increased odds of screen failure among all other groups (HB OR = 4.0 95% CI 2.0, 9.1; HW OR = 2.0 95% CI 1.6, 2.4; NHA OR = 2.5 95% CI 1.4, 4.5; NHB OR = 2.1, 95% CI 1.6, 2.7). Observed differences were consistent across APOE ε4 carriers and non‐carriers. Conclusion: Differential rates of amyloid eligibility were observed despite the lack of systematic sample bias due to clinical or cognitive requirements observed in previous studies. Potential explanations for these observations include differences in clinical trial access, incidences of elevated amyloid, needed cutoffs for biomarker assays, and confounding due to comorbidities or other unmeasured covariates. This work is supported by a public‐private partnership between Alzheimer’s Clinical Trial Consortium (U24 AG057437) and Eisai.
Disparities by Race and Ethnicity Among Adults Recruited for a Preclinical Alzheimer Disease Trial
Question: Are there racial/ethnic differences associated with recruitment sources and reasons for ineligibility among preclinical Alzheimer disease clinical trial participants?
Findings: In this cross-sectional study of screening data for 5945 participants from a preclinical Alzheimer disease trial, Black, Hispanic, and Asian participants were recruited from local efforts compared with White participants who were recruited from more distributed efforts. Adjusted analysis showed that underrepresented racial/ethnic communities were more likely to be ineligible after the first screening visit.
Meaning: These findings suggest that there are racial and ethnic disparities in preclinical AD clinical trial enrollment that will require a comprehensive approach to study design and recruitment strategies to minimize disproportionate enrollment.
Abstract
Importance: Underrepresentation of many racial/ethnic groups in Alzheimer disease (AD) clinical trials limits generalizability of results and hinders opportunities to examine potential effect modification of candidate treatments.
Whole Dude experiences Whole Bias: Michigan Medicine and University of Michigan reveal their ignorance of the term called Race. There is no Race of People called Indian. However, several Indians, Iranians and Germans celebrate their Aryan Race heritage. I ask Michigan Medicine and University of Michigan to share its educational experience and publish its Theory of Man
University of Michigan and Michigan Medicine must learn that there is no human race called Indian
As a research participant, Whole Dude investigates the problem of Selection Bias in the Selection Process used by the Research Investigator at University of Michigan. The Selection Bias is inherent in the Selection process for it is gathering information of its human subjects outsides the boundaries of the declared purpose of the Study.
The AHEAD Study Research Protocol has not identified the basis for discovering the identity of a multicellular human organism. I can answer the questions I am asked. Do I have the ability to communicate my answers to the cells of my own body and reflect that identity in the living functions they perform to keep me alive?
Whole Dude at Whole Foods rejects the concept of race and ethnicity to identify the Anatomically Modern Man called Homo sapiens sapiens
SPIRITUALITY SCIENCE – THE HUMAN SPECIES: THE GERMAN PHYSIOLOGIST, COMPARATIVE ANATOMIST, AND SCHOLAR, JOHANN FRIEDRICH BLUMENBACH (1752-1840) IS RECOGNIZED AS THE FATHER OF PHYSICAL ANTHROPOLOGY. HE SHOWED THE VALUE OF COMPARATIVE ANATOMY IN THE STUDY OF MAN’S HISTORY.SPIRITUALITY SCIENCE – THE HUMAN SPECIES: BLUMENBACH HAD A COLLECTION OF 60 HUMAN SKULLS AND HE PROPOSED ONE OF THE EARLIEST CLASSIFICATIONS OF THE RACES OF MANKIND USING COMPARATIVE ANATOMY.
Johann Friedrich Blumenbach is recognized as the Father of Physical Anthropology for his work De Generis Humani Varietate Nativa (1775-76). His research in the measurement of human skulls led him to divide mankind into five great families; Caucasian, Mongolian, Malayan, Ethiopian, and American. Human Species may include varieties that can be grouped into Races by using some common morphological traits.
University of Michigan and Michigan Medicine fail to provide the scientific basis for the racial classification it uses.
Whole Dude at Whole Foods applies the knowledge of Human Anatomy to recognize Human Identity
As a research participant, Whole Dude investigates the problem of Selection Bias in the Selection Process used by the Research Investigator at University of Michigan. The Selection Bias is inherent in the Selection process for it is gathering information of its human subjects outsides the boundaries of the declared purpose of the Study.Whole Dude ant Whole Foods applies the knowledge of Human Anatomy to recognize Human Identity.
In 1965, while Whole Dude was a student of Human Anatomy at Kurnool Medical College had the opportunity to know about Dr. J. C. B. Grant (1886-1973), the author of Grant’s Atlas of Anatomy. The 5th Edition of his Atlas was published in 1962 and was available in India in our Medical College Library.
Born in Loanhead (south of Edinburgh) in 1886, Grant studied medicine at the University of Edinburgh Medical School and graduated with an M.B., Ch.B. degree in 1908. While at Edinburgh, he worked under the renowned anatomist Daniel John Cunningham.
badge, headdress, British, Royal Army Medical Corps (INS 8067) Brass cap badge of the rod of Aesculapius with a serpent entwined round it, head uppermost and looking left, all within a laurel wreath. Above, an Imperial (King’s) crown and below, a scroll bearing ROYAL ARMY MEDICAL CORPS. Slider to reverse. Copyright: � IWM. Original Source: http://www.iwm.org.uk/collections/item/object/30078877The Cap Badges and the Insignia of the British Royal Medical Corps and the Indian Army Medical Corps reveal the Whole Dude-Grant Connection. The Indian Army Medical Corps was created from the British Royal Army Medical Corps.
Grant became a decorated serviceman of the Royal Army Medical Corps during the First World War before moving to Canada. He established himself as an ‘anatomist extraordinary’ at the University of Toronto, publishing three textbooks that form the basis of Grant’s Anatomy. The textbooks are still used in anatomy classes today, and made unforgettable memories for those who found themselves in his classes nearly a century ago. One of Grant’s many accomplishments was establishing a division of histology within the department.
Whole Dude at Whole Foods applies the knowledge of Human Anatomy to recognize Human Identity
As a medical student, Whole Dude used Grant’s Atlas of Anatomy, the seminal work of Scottish-born Dr. John Charles Boileau Grant, who would become the chair of Anatomy at the University of Toronto in 1930 and retired in 1965.
John Charles Boileau Grant (1886–1973)
As a medical student, Whole Dude used Grant’s Atlas of Anatomy, the seminal work of Scottish-born Dr. John Charles Boileau Grant, who would become the chair of Anatomy at the University of Toronto in 1930 and retired in 1965.
The author of Grant’s Atlas of Anatomy (1943), Grant used to train thousands of medical students around the world. He came to University of Toronto’s Faculty of Medicine from University of Manitoba (and previously Edinburgh), and was Chair of the Department of Anatomy there from 1930 to 1965. Although he is best known for this famous atlas, his research and teaching also included biological anthropology, as evidenced by such work as Anthropometry of the Cree and Saulteaux Indians in Northeastern Manitoba (Archaeological Survey of Canada 1929). The human skeletal collection he formed, the “J.C.B. Grant Collection,” is still a core collection for human osteology in the Department of Anthropology at University of Toronto. He is also remembered in the Grant’s Museum at the Medical Sciences Building at the University of Toronto. This museum, with its displays of anatomical specimens, many of which were dissected by Grant himself, continues to be used in an active learning environment by more than 1000 students each year.
Students continue to use Grant’s textbooks today, and for the more artistic anatomist there’s even a Grant’s Anatomy Coloring Book, published in 2018.
Whole Dude at Whole Foods applies the knowledge of Human Anatomy to recognize Human Identity
At the University of Toronto, Dr.McMurrich, Chair of Anatomy was succeeded as chairman in 1930 by Dr. John Charles Boileau Grant. Dr. Grant wrote three text books, of which “An Atlas of Anatomy” (published in 1943) rapidly gained international prominence and is still, one of the most widely used anatomical atlases in the world. It is now known as “Grant’s Atlas of Anatomy” and is in its tenth edition. The atlas was based on a series of elegant dissections done either by Grant or by others under his supervision. Many of these dissections are currently housed in Grant’s Museum at the University of Toronto.
The Whole Dude-Grant Connection is about knowing the man, the building blocks and the structural units and organization of the human body. To defend the human existence, the Whole Dude-Grant Connection lays the emphasis on knowing the person who is at risk apart from knowing the agent posing the risk.
The Identity of Multicellular Human Organism:
Cunningham’s Manual of Practical Anatomy provides Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs, and Organ Systems.
Daniel John Cunningham was born on 15 April 1850 in Scotland. After his initial schooling at his home town, Crieff, he took up the study of medicine at the University of Edinburgh and passed with honours. He is best known for the excellent series of dissection manuals, namely Cunningham’s Dissection Manuals. Cunningham’s Manual of Practical Anatomy provides Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs, and Organ Systems.
Cunningham’s Manual of Practical Anatomy provides Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs, and Organ Systems.Cunningham’s Manual of Practical Anatomy provides Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs, and Organ Systems.Cunningham’s Manual of Practical Anatomy provides Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs, and Organ Systems.Cunningham’s Manual of Practical Anatomy provides Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs, and Organ Systems.Cunningham’s Manual of Practical Anatomy provides Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs, and Organ Systems.
Whole Dude learned the truths about the living human body and about Life while dissecting the dead human bodies in a systematic manner. The Manual of Practical Anatomy which guides us through this entire process was published in England. The author Dr. Daniel John Cunningham prepared the Manual while dissecting cadavers of British or Irish citizens. He had never encountered cadavers of Indian citizens. At Kurnool Medical College, Kurnool, Andhra Pradesh, India, where Whole Dude was a student, the Department of Anatomy obtains dead bodies from Government General Hospital Kurnool and most of the deceased are the poor, and illiterate people of that region. None of the deceased had the chance to know this man called Cunningham and Cunningham had no knowledge about the existence of these people who arrive on our dissection tables. But, as the dissection of the human body proceeds, inch, by inch, we recognize the anatomical parts as described by Cunningham. The manual also lists some anatomical variations and we very often exchange information between various dissection tables and recognize the variations mentioned. The dissections also involve slicing the organs and studying them, both macroscopically, and microscopically. We did not miss any part of the human body.
Cunningham’s Manual of Practical Anatomy provides Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs, and Organ Systems.
So what is the Identity of this Human person or Human subject? How does the living Human organism maintain its Identity and Individuality? Apart from the Cultural Traditions of India, several Schools of Religious Thought claim that the Human Individual and its Identity is represented by Human Soul. Where does this soul exist in the human body? What is the location if the soul is present in the living person? Does man have a soul?How does the human organism acquires Knowledge about its own structures and the functions they perform?
How does the multicellular human organism recognizes its own Identity and Individuality?
The Whole Dude-Grant Connection applies the knowledge of Human Anatomy to recognize Human Identity. A brief glance at the face is enough for most people to identify one another. Face recognition is a basic feature of human identity and recognition.
A brief glance at the face is enough for most people to identify one another. However, man does not exist with the same identity during the course of his life. The word identity describes the condition or fact of being a specific person. Identification is the process by which a person can be identified in an accurate and consistent manner. The morphological or the external appearance of a person is subject to constant changes and it differs in a significant manner during the various stages of life such as infancy, boyhood, adulthood, and old age. The term individuality describes the sum of the characteristics or qualities that set one person apart from others. The condition of being individual, or different from others establishes the indivisibility of man. Man is unique, original, one kind of person who has not existed before and would not also exist in future even when he shares the same identical genome. Two identical twins could be correctly identified as two different individuals. I had proposed the Law of Individuality and Creation which claims that man exists as Individual and has no choice in this conditioned nature of subjective physical existence in the world. Man can only exist as Individual with Individuality.
The Whole Dude-Grant Connection applies the knowledge of Human Anatomy to recognize Human Identity. If Identity described by the Phenotype establishes one face of the Coin, the Individuality describes the second face of the same coin and is established by the Genotype. While being the same, the Genotype presents the Individual with varying features of identification.
The Identification Technology:
The Whole Dude-Grant Connection applies the knowledge of Human Anatomy to recognize Human Identity. Using Fingerprints is the oldest method of Identification. The Fingerprint is electronically read by a sensor plate.
Biometrics is that branch of Biology which deals with its data statistically and by mathematical analysis. Using Fingerprints is the oldest method of Identification using biometric information. People have tiny ridges of skin on their fingers. These ridges form through a combination of genetic and environmental factors. The genetic makeup, the position of the fetus in the womb, and the composition and density of surrounding amniotic fluid play a role in how every individual ridge on the skin surface of finger will form. Fingerprints are a unique marker for a person, even an identical twin. Fingerprint analysis can define the differences between two fingerprint impressions.
The Whole Dude-Grant Connection applies the knowledge of Human Anatomy to recognize Human Identity. Fingerprints are a unique marker for a person and Fingerprint analysis can define the differences between Fingerprints.
The Fingerprint is electronically read. The corrugated ridges of the skin are non-continuous and form a pattern that has distinguishing features or minutiae. Two varieties of Fingerprint scanning technology are currently used; the optical Fingerprint scanners and the Capacitance Fingerprint scanner that uses a computerized analysis.
Iris Recognition Technology:
The Whole Dude-Grant Connection applies the knowledge of Human Anatomy to recognize Human Identity. The Iris is the most unique feature visible on the human body.Iris Scan Recorder uses pattern recognition techniques based on images of the Iris.
Iris Scanners use pattern recognition techniques based on images of the irides(Irises) of an individual’s eyes.
The Whole Dude-Grant Connection applies the knowledge of Human Anatomy to recognize Human Identity. Identity and Individuality. How does the multicellular human organism recognizes its own Identity?
No two irides being the same, even in identical twins, individuals could be identified with accuracy and consistency.
DNA Analysis:
The Whole Dude-Grant Connection applies the knowledge of Human Anatomy to recognize Human Identity. A small sample of DNA is amplified by using Polymerase Chain Reaction or PCR. The Short Tandem Repeat Analysis examines how often base pairs repeat in specific locations on a DNA strand.
A small sample of DNA is amplified by using Polymerase Chain Reaction or PCR. In a method described as Short Tandem Repeat Analysis, it is examined to find how often base pairs repeat in specific locations or loci on a given DNA strand. These can be dinucleotide, trinucleotide, tetranucleotide, or pentanucleotide repeats; that is repetition of 2, 3, 4, or 5 base pairs. Very often, the investigator looks for tetranucleotide or pentanucleotide repeats in the DNA sample.
The Whole Dude-Grant Connection applies the Knowledge of Human Anatomy to recognize Human Identity.
The likelihood that any two individuals (except identical twins) will have the same 13-loci DNA profile can be as high as 1 in 1 billion or greater.
Biometric Facial Recognition Technology:
The Whole Dude-Grant Connection applies the knowledge of Human Anatomy to recognize Human Identity. Every face has numerous distinguishable landmarks, the different peaks and valleys that make up facial features.
Every face has numerous distinguishable landmarks, the different peaks and valleys that make up facial features. These landmarks are known as nodal points. Each human face has approximately 80 nodal points.
The Whole Dude-Grant Connection applies the knowledge of Human Anatomy to recognize Human Identity. Identity and Individuality. How does the multicellular human organism recognizes its own identity?
Distance between the eyes, width of the nose, depth of the eye sockets, the shape of the cheekbones, the length of the jawline and other features are used as nodal points. These nodal points are measured creating a numerical code called a face print, representing the face in the database and comparison is made between images of face. 2D or 3D image of a person’s face uses distinct features of the face where rigid tissue and bone is most apparent, such as the curves of the eye socket, nose, and chin to identify the subject.
The Whole Dude-Grant Connection applies the knowledge of Human Anatomy to recognize Human Identity. Identity and Individuality. In a multicellular human organism, who recognizes the Identity of the human person?
Unique templates are created from measurements between key points on the face and these measurements provide identification of the individual.
Skin Biometrics – Skin Surface Texture Analysis:
The Whole Dude-Grant Connection applies the knowledge of Human Anatomy to recognize Human Identity. The uniqueness of Skin Texture offers an opportunity to identify differences between identical twins.The Whole Dude-Grant Connection applies the knowledge of Human Anatomy to recognize Human Identity. Surface Texture Analysis creates a Skin Print by using local information about skin texture at various points on the surface.
The Surface Texture Analysis algorithm operates on the top percentage of results as determined by the Local feature analysis. This method creates a Skin Print and performs either a 1:1 or 1:N match for verification or identification. It can identify the differences between identical twins.
Identity, Individuality, and Consciousness:
The Whole Dude-Grant Connection applies the knowledge of Human Anatomy to recognize Human Identity. Identity, Individuality, and Consciousness
Man describes his identity in terms of his personal name, age, gender, race, ethnicity, place of origin, language, religion, political, occupational, or social affiliation. In reality, the man is an association of trillions of individual cells.
The Whole Dude-Grant Connection applies the knowledge of Human Anatomy to recognize Human Identity. Identity and Individuality. How does the multicellular human organism recognizes its own Identity?
The human organism is a conscious being and the function called consciousness achieves functional unity of all these individual cells and works for the benefit of the individual who always maintains his individuality.
The Whole Dude-Grant Connection applies the knowledge of Human Anatomy to recognize Human Identity. Identity and Individuality. Cognitive Biology must address the issue of cognition of human Identity. In the multicellular human organism, who recognizes the Identity of the Human Individual?
This is possible because individual cells have the ability to recognize the presence of other living cells in their environment and display functional subordination to serve the purpose of the whole organism.
“All of our experience indicates that life can manifest itself only in a concrete form, and that it is bound to certain substantial loci. These loci are cells and cell formations. But we are far from seeking the last and highest level of understanding in the morphology of these loci of life. Anatomy does not exclude physiology, but physiology certainly presupposes anatomy. The phenomena that the physiologist investigates occur in special organs with quite characteristic anatomical arrangements; the various morphological parts disclosed by the anatomist are the bearers of properties or, if you will, of forces probed by the physiologist; when the physiologist has established a law, whether through physical or chemical investigation, the anatomist can still proudly state: This is the structure in which the law becomes manifest.” – Rudolf Virchow
The phenomena that the physiologist investigates occur in special organs with quite characteristic anatomical arrangements; the various morphological parts disclosed by the anatomist are the bearers of properties or, if you will, of forces probed by the physiologist; when the physiologist has established a law, whether through physical or chemical investigation, the anatomist can still proudly state: This is the structure in which the law becomes manifest.” – Rudolf Virchow
Michigan Medicine AHEAD Study uses unscientific demographic information to ascertain the Identity of Whole Dude for participation in Medical Research Project
Whole Foods-Whole Inspiration-Whole LanguageWhole Foods Arrives in Ann Arbor, September 1993Whole Foods opened its Store in Ann Arbor on September 16, 1993. Whole Foods, Whole People and Whole Planet inspire Whole Dude to invent Whole Phrases: Whole Linguistics – Whole Language. The concept of Whole Cookie and Whole Love. Whole Dude uses the phrase Whole Linguistics to describe three entities; 1. Language User, 2. Language Interpreter and 3. Language Creator. Image Credit: Agenda Publications, Ann Arbor District Library, Issue Dates, September 1993, December 1997 and February 1998.Michigan Medicine should have known better and must use valid, verified principles to identify every Human Being as a Specific Individual with Individuality without depending upon unverified claims about Race and Ethnicity. Michigan Medicine AHEAD Study has no Research Protocol to verify the Identity and Individuality of the Complex, Multicellular, Human Organism
Man describes his identity in terms of his personal name, age, gender, race, ethnicity, place of origin, language, religion, political, occupational, or social affiliation. In reality, the man is an association of trillions of individual cells. Michigan Medicine should have known better and must use valid, verified principles to identify every Human Being as a Specific Individual with Individuality without depending upon unverified claims about Race and Ethnicity.
Michigan Medicine AHEAD Study has no Research Protocol to verify the Identity and Individuality of the Complex, Multicellular, Human Organism
The AHEAD Study is researching the safety and effectiveness of an investigational medication in people who might be at increased risk for developing memory loss associated with Alzheimer’s Disease. The study is looking for participants age 55-80 years old, who have generally normal memory function in daily life, and who are not being treated for memory problems. For individuals age 55-64 years old, an additional risk factor is required, such as a parent or sibling with Alzheimer’s Disease or previous biomarker testing showing increased risk for developing Alzheimer’s Disease. This study sees participants in Ann Arbor. Contact Lauren Mackenzie at spearsl@med.umich.edu or 734-232-2415, Clinical Research Coordinator, Neurology Clinical Trials Organization (NeCTO), NCAC.
On Tuesday, December 05, 2023, at the Michigan Clinical Research Unit (MCRU) at the Cardiovascular Center (CVC), Whole Dude was interviewed for participating in the AHEAD Study. Whole Dude was asked to provide their demographic information to register their personal identity for participation in the Medical Research Project. Further, Whole Dude was asked to provide information about their Race which is entirely determined by the Place of their Birth, and the Country of their Birth. Whole Dude was asked to verify their Ethnicity using the one and only Criteria which relates to the Ethnicity of Hispanic people.
Whole Dude remains totally dismayed to learn that the Research Project has not established its own Protocol to describe the Identity and Individuality of the Specific Human Individual who may be included as a Research Subject in Clinical Medical Research. Michigan Medicine should have known better and must use valid, verified principles to identify every Human Being as a Specific Individual with Individuality without depending upon unverified claims about Race and Ethnicity.
Michigan Medicine AHEAD Study has no Research Protocol to verify the Identity and Individuality of the Complex, Multicellular, Human Organism Michigan Medicine should have known better and must use valid, verified principles to identify every Human Being as a Specific Individual with Individuality without depending upon unverified claims about Race and Ethnicity.
Man is constituted as a Biotic Community of socially interacting cells and microbes
Whole Dude at Whole Foods examines the complex issues of identity and individuality in the multicellular human organismWhole Dude at Whole Foods examines the complex issues of identity and individuality in the multicellular human organismWhole Dude at Whole Foods examines the complex issues of identity and individuality in the multicellular human organism. The Law of Individuality leaves the Individual with no choice other than that of expressing variability while being a member of a Social Group which may have a fixed Identity.Whole Dude at Whole Foods examines the complex issues of identity and individuality in the multicellular human organism
The Cellular and the Molecular Basis of Identity and Individuality
Whole Dude at Whole Foods has Cellular and Molecular Basis for his Identity and Individuality. Human Identity undergoes changes due to the aging process but the Human Individuality persists unchanged. Individuality and the Genome. The Law of Individuality governs all Individual Living Things.Whole Dude at Whole Foods has Cellular and Molecular Basis for his Identity and Individuality. Human Identity undergoes changes due to the aging process but the Human Individuality persists unchanged. Individuality and the Genome. The Law of Individuality governs all Individual Living Things.Whole Dude at Whole Foods has Cellular and Molecular Basis for his Identity and Individuality. Human Identity undergoes changes due to the aging process but the Human Individuality persists unchanged. Individuality and the Genome. The Law of Individuality governs all Individual Living Things.
In 1965, while Whole Dude was a student of Human Anatomy at Kurnool Medical College, they had the opportunity to know Dr. J. C. B. Grant (1886-1973), the author of Grant’s Atlas of Anatomy. The 5th Edition of his Atlas was published in 1962 and was available in India in their Medical College Library.
John Charles Boileau Grant (1886–1973)
Dr. J C B Grant. Whole Dude coined the phrase Whole Individualism to discover Man by a study of the building blocks, the structural units and organization of the human body. To defend human existence, Whole Individualism lays the emphasis on knowing the person who is at risk apart from knowing the agent posing the risk.
Born in Loanhead (south of Edinburgh) in 1886, Grant studied medicine at the University of Edinburgh Medical School and graduated with an M.B., Ch.B. degree in 1908. While at Edinburgh, he worked under the renowned anatomist Daniel John Cunningham. Grant became a decorated serviceman of the Royal Army Medical Corps during the First World War before moving to Canada.
badge, headdress, British, Royal Army Medical Corps (INS 8067) Brass cap badge of the rod of Aesculapius with a serpent entwined round it, head uppermost and looking left, all within a laurel wreath. Above, an Imperial (King’s) crown and below, a scroll bearing ROYAL ARMY MEDICAL CORPS. Slider to reverse. Copyright: � IWM. Original Source: http://www.iwm.org.uk/collections/item/object/30078877The Cap Badges and the Insignia of the British Royal Medical Corps and the Indian Army Medical Corps reveal the Whole Dude-Grant Connection. The Indian Army Medical Corps was created from the British Royal Army Medical Corps.
He established himself as an ‘anatomist extraordinary’ at the University of Toronto, publishing three textbooks that form the basis of Grant’s Anatomy. The textbooks are still used in anatomy classes today, and made unforgettable memories for those who found themselves in his classes nearly a century ago. One of Grant’s many accomplishments was establishing a division of histology within the department.
Whole Dude at Whole Foods has Cellular and Molecular Basis for his Identity and Individuality. Human Identity undergoes changes due to the aging process but the Human Individuality persists unchanged. Individuality and the Genome. The Law of Individuality governs all Individual Living Things.
As a medical student, Whole Dude used Grant’s Atlas of Anatomy, the seminal work of Scottish-born Dr. John Charles Boileau Grant, who was the chair of Anatomy at the University of Toronto in 1930 and retired in 1965.
Students continue to use Grant’s textbooks today, and for the more artistic anatomist there’s even a Grant’s Anatomy Coloring Book, published in 2018.
Whole Dude at Whole Foods has Cellular and Molecular Basis for his Identity and Individuality. Human Identity undergoes changes due to the aging process but the Human Individuality persists unchanged. Individuality and the Genome. The Law of Individuality governs all Individual Living Things.
At the University of Toronto, Dr.McMurrich, Chair of Anatomy was succeeded as chairman in 1930 by Dr. John Charles Boileau Grant. Dr. Grant wrote three text books, of which “An Atlas of Anatomy” (published in 1943) rapidly gained international prominence and is still, one of the most widely used anatomical atlases in the world. It is now known as “Grant’s Atlas of Anatomy” and is in its tenth edition. The atlas was based on a series of elegant dissections done either by Grant or by others under his supervision. Many of these dissections are currently housed in Grant’s Museum at the University of Toronto.
The concept of Whole Dude relates to knowing the man, the building blocks and the structural units and organization of the human body. To defend human existence, Whole Dude lays the emphasis on knowing the person who is at risk apart from knowing the agent posing the risk.
The Identity of Multicellular Human Organism:
The cellular and the molecular basis of human identity and human individuality. Cunningham’s Manuals of Practical Anatomy provide Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems
Daniel John Cunningham was born on 15 April 1850 in Scotland. After his initial schooling at his home town, Crieff, he took up the study of medicine at the University of Edinburgh and passed with honours. He is best known for the excellent series of dissection manuals, namely Cunningham’s Dissection Manuals. Cunningham’s Manual of Practical Anatomy has provided me the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems.
The cellular and the molecular basis of human identity and human individuality. Cunningham’s Manuals of Practical Anatomy provide Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ SystemsThe cellular and the molecular basis of human identity and human individuality. Cunningham’s Manuals of Practical Anatomy provide Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ SystemsThe cellular and the molecular basis of human identity and human individuality. Cunningham’s Manuals of Practical Anatomy provide Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems
Whole Dude learned the truths about the living human body and about Life while dissecting dead human bodies in a systematic manner. The Manual of Practical Anatomy which guides students through this entire process was published in England. The author Dr. Daniel John Cunningham prepared the Manual while dissecting cadavers of British or Irish citizens. He never encountered cadavers of Indian citizens. At Kurnool Medical College, Kurnool, Andhra Pradesh, India, where Whole Dude was a student, the Department of Anatomy obtains dead bodies from Government General Hospital Kurnool and most of the deceased are the poor and often illiterate people of that region. None of the deceased had the chance to know this man called Cunningham and Cunningham had no knowledge about the existence of these people who arrive on our dissection tables. But, as the dissection of the human body proceeds, inch, by inch, we recognize the anatomical parts as described by Cunningham. The manual also lists some anatomical variations and we very often exchange information between various dissection tables and recognize the variations mentioned. The dissections also involve slicing the organs and studying them, both macroscopically, and microscopically. We did not miss any part of the human body.
The cellular and the molecular basis of human identity and human individuality. Cunningham’s Manuals of Practical Anatomy provide Whole Dude the learning tools to know and understand Man’s External and Internal Reality and its Identity as described by Cells, Tissues, Organs,and Organ Systems
So what is the Identity of this Human Person who experiences his life using Sensory Experiences such as Taste? How does the living Human organism maintains its Identity and Individuality? Apart from the Cultural Traditions of India, several Schools of Religious Thought claim that the Human Individuality and true or real Identity is represented by Human Soul. Does man have a soul? Where does this soul exist in the human body? What is the location if the soul is present in the living person? How does the human organism acquires Knowledge about its own structures and the functions they perform?To know the burdens of Life, Whole Dude asks his readers to know the reality of man and the nature of his existence.
The cellular and the molecular basis of human identity and human individuality. THE KNOWER AND THE KNOWING-SELF: IN THIS IMAGE OF HUMAN BRAIN, THE GREEN PORTION OF BRAIN STEM IS CALLED RETICULAR FORMATION. WHOLE DUDE DESCRIBES IT AS THE KNOWING-SELF AND IT IS THE “KNOWER” OF THE HUMAN BODY WHICH CONSTANTLY CHANGES ITS MORPHOLOGICAL APPEARANCE UNDER THE INFLUENCE OF TIME CALLED THE AGING PROCESS.
Human Identity vs Human Individuality:
Whole Dude at Whole Foods has Cellular and Molecular Basis for his Identity and Individuality. Human Identity undergoes changes due to the aging process but the Human Individuality persists unchanged. Individuality and the Genome. The Law of Individuality governs all Individual Living Things.
Human Identity may involve a variety of factors such as facial appearance, age, gender, race, ethnicity, language, religion, culture, nationality, sexual orientation, social and occupational status. Whereas human individuality has to be evaluated by using the markers that the human body uses to recognize its own Self and defends its own existence from threats posed by Non-Self.
Whole Dude at Whole Foods has Cellular and Molecular Basis for his Identity and Individuality. Human Identity undergoes changes due to the aging process but the Human Individuality persists unchanged. Individuality and the Genome. The Law of Individuality governs all Individual Living Things.Whole Dude at Whole Foods has Cellular and Molecular Basis for his Identity and Individuality. Human Identity undergoes changes due to the aging process but the Human Individuality persists unchanged. Individuality and the Genome. The Law of Individuality governs all Individual Living Things.Whole Dude at Whole Foods has Cellular and Molecular Basis for his Identity and Individuality. Human Identity undergoes changes due to the aging process but the Human Individuality persists unchanged. Individuality and the Genome. The Law of Individuality governs all Individual Living Things.The cellular and the molecular basis of human identity and human individuality. In the final analysis, the human organism is a biotic community of trillions of individual, independent cells.The cellular and the molecular basis of human identity and human individuality: THE MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) IS THE HUMAN LEUKOCYTE ANTIGEN (HLA) GENE CLUSTER ON CHROMOSOME 6. HUMAN ORGANS AND TISSUES CANNOT BE TRANSPLANTED OR GRAFTED INTO THE BODIES OF UNRELATED INDIVIDUALS. HUMAN IDENTITY MUST BE DISCOVERED AT MOLECULAR LEVEL TO ESTABLISH THE AFFINITY BETWEEN TWO HUMAN INDIVIDUALS.Whole Dude at Whole Foods has Cellular and Molecular Basis for his Identity and Individuality. Human Identity undergoes changes due to the aging process but the Human Individuality persists unchanged. Individuality and the Genome. The Law of Individuality governs all Individual Living Things.
THE MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) IS THE HUMAN LEUKOCYTE ANTIGEN (HLA) GENE CLUSTER ON CHROMOSOME 6. HUMAN ORGANS AND TISSUES CANNOT BE TRANSPLANTED OR GRAFTED INTO THE BODIES OF UNRELATED INDIVIDUALS. HUMAN IDENTITY MUST BE DISCOVERED AT MOLECULAR LEVEL TO ESTABLISH THE AFFINITY BETWEEN TWO HUMAN INDIVIDUALS.
Human Individuality and the Genome
Individuality and the Genome. A COLONY OF GENETICALLY IDENTICAL E. COLI IS ACTUALLY A MOB OF ‘INDIVIDUALS’.
Understanding Individuality:
Individuality and the Genome. Even among simple forms of life, like the common bacterium E. coli, genetics only partly determines what any one organism is like. E. coli expresses its individuality in many ways. All the bacilli above are genetically identical, but the shades show differences in the production of proteins that digest lactose.Credit…Dr. Michael Elowitz
Dr. Michael Elowitz, Physicist at California Institute of Technology has conducted experiments on colonies of genetically identical (Clones) E. coli bacteria under identical experimental conditions and has discovered that the clones behave in different ways which could be viewed as an expression of ‘individuality’.
Whole Dude at Whole Foods has Cellular and Molecular Basis for his Identity and Individuality. Human Identity undergoes changes due to the aging process but the Human Individuality persists unchanged. Individuality and the Genome. The Law of Individuality governs all Individual Living Things.
E. coli bacteria in billions populate our intestines. Typical E. coli bacillus has about 4,000 genes. Human cells have about 20,000 genes. The bacteria have fingerprints of their own and even when they share the exact same genome, they could still be identified as ‘individuals’.
Individuality and the Genome. Dr. Michael Elowitz and Dr. Long Cai are developing a platform through which cells can self-record their lineage and molecular event histories directly into their own DNA as they create new tissues, particularly in the brain. This research will help to address how individual cells in a developing embryo diversify into many distinct cell types, each playing its unique role in the organism.
The key to understanding E. coli’s fingerprints is to recognize that the bacteria are not simple machines. Unlike wires and transistors, E. coli’s molecules are floppy, twitchy and unpredictable. In an electronic device, like a computer or a radio, electrons stream in a steady flow through the machine’s circuits, but the molecules in E. coli jostle and wander. When E. coli begins using a gene to make a protein, it does not produce a smoothly increasing supply. It spurts out the proteins in fits and starts. One clone may produce half a dozen copies of a protein in an hour, while a clone right next to it produces none.
Michael Elowitz, a physicist at Caltech, put these bursts on display in an elegant experiment. He and his colleagues incited E. coli to produce its proteins for feeding on lactose. Dr. Elowitz and his colleagues added extra genes to the bacteria so that when they made lactose-digesting proteins, they also released light.
The bacteria, Dr. Elowitz found, did not produce a uniform glow. They flickered, sometimes brightly, sometimes dimly. And when Dr. Elowitz took a snapshot of the colony, it was not a uniform sea of light. Some microbes were dark at that moment while others shone at full strength.
At the very least, E. coli’s individuality should be a warning to those who would put human nature down to any sort of simple genetic determinism. Living things are more than just programs run by genetic software. Even in minuscule microbes, the same genes and the same genetic network can lead to different fates.
The bacteria have fingerprints of their own and even when they share the same genome, they could still be identified as individuals.
Individuality and the Genome. Man is constituted as a Biotic Community of socially interacting cells and microbes
Humans differ from one another in too many different ways and it is hard to count. The current human population of over six billion could be identified as the same number of individuals. Each human being has an unique genome of his own. There are millions of typographical differences between one genome and another human genome. Even identical twins are not truly identical at all as identical genes in our cells can behave differently.
Living entities are not like simple machines. When we use a gene to make a protein, the gene may not produce a smoothly increasing supply of that protein. The gene tends to work in fits and starts and spurts out the protein. Identical genes can behave differently as the gene makes protein or remains silent depending upon the ‘Methyl’ groups that cap the DNA strands and function as ‘transducers’. These ‘Methyl’ groups sometimes fall off of DNA or become attached to new spots. Hence genetically identical individuals can have different physical identities in the natural world. The protein molecules that make up living entities, turn them into individuals.
The Irrelevance of Evolution:
CHARLES DARWIN’S ORIGIN OF SPECIES (1859) PROPOSES A MECHANISTIC, NON-PURPOSIVE ACCOUNT OF EVOLUTION AS THE PRODUCT OF NATURAL SELECTION OF RANDOMLY PRODUCED GENETIC MUTATIONS.
In the natural world, all living entities exist as individuals and express their individuality. The Theory of Evolution proposes that a species can descend or arrive to become a new species by changing its genome in a gradual and incremental manner using a mechanism that is described as Natural Selection. As per Darwinism, the mechanism of natural selection operates via a process of random and unguided mutations in the genetic code that changes the genome and eventually produces the ‘biodiversity’ that we witness in the natural world.
Individuality and the Genome. The phenomenon of Diversity must be studied beyond the realm of genes, genetic codes, and genomes. Cytoplasm and its organs must be studied to understand the physiological basis of Diversity
This Theory of Evolution has no relevance to the ultimate identity of each individual member of a given species. This identity is dictated by interplay between the various components of each individual cell and its interactions with other cells. With the same genomes or different genomes, the living entities can only exist as individuals and they have no other choice. The evolutionary connections are not relevant to this identity. To understand the phenomenon of biodiversity, we will be forced to look at each individual member of each given species.
The Law of Individuality:
Individuality and the Genome. The Law of Individuality formulates the phenomenon of Human Individuality.
Whole Dude states that the Law of Individuality governs all the living entities and is manifested in various biological phenomena. The genes and the genetic code function in accordance with the Law of Individuality. Hence, Whole Dude describes Individuality as a Trade Mark. It is the characteristic of a biological entity. Genes and the genetic codes are the tools that an organism uses to express its Individuality. Each organism assembles its own kind of protein molecules to define its identity and to defend its existence in the natural world.
Individuality and the Genome. The Law of Individuality formulates the phenomenon of Changing Human Identity and the Unchanging Human Individuality.
Whole Dude is the Given Name of a known, verified, specific Whole Person
Whole Foods-Whole Inspiration-Whole LanguageWhole Foods Arrives in Ann Arbor, September 1993Whole Foods opened its Store in Ann Arbor on September 16, 1993. Whole Foods, Whole People and Whole Planet inspire Whole Dude to invent Whole Phrases: Whole Linguistics – Whole Language. The concept of Whole Cookie and Whole Love. Whole Dude uses the phrase Whole Linguistics to describe three entities; 1. Language User, 2. Language Interpreter and 3. Language Creator. Image Credit: Agenda Publications, Ann Arbor District Library, Issue Dates, September 1993, December 1997 and February 1998.
What is Identity and What is Individuality?
Human Identity and Individuality: A brief glance at the face is enough for most people to identify one another. Face recognition is a basic feature of human identity and recognition.
A brief glance at the face is enough for most people to identify one another. However, man does not exist with the same identity during the course of his life. The word identity describes the condition or fact of being a specific person. Identification is the process by which a person can be identified in an accurate and consistent manner.
The morphological or the external appearance of a person is subject to constant changes and it differs in a significant manner during the various stages of life such as infancy, boyhood, adulthood, and old age.
The morphological or the external appearance of a person is subject to constant changes and it differs in a significant manner during the various stages of life such as infancy, boyhood, adulthood, and old age. The term individuality describes the sum of the characteristics or qualities that set one person apart from others. The condition of being individual, or different from others establishes the indivisibility of man. Man is unique, original, one kind of person who has not existed before and would not also exist in future even when he shares the same identical genome. Two identical twins could be correctly identified as two different individuals. I propose the Law of Individuality and Creation which claims that man exists as Individual and has no choice in this conditioned nature of subjective physical existence in the world. Man can only exist as Individual with Individuality.
Human Identity and Individuality: If Identity described by the Phenotype establishes one face of the Coin, the Individuality describes the second face of the same coin and is established by the Genotype. While being the same, the Genotype presents the Individual with varying features of identification.
The Identification Technology:
Human Identity and Individuality: Using Fingerprints is the oldest method of Identification. The Fingerprint is electronically read by a sensor plate.
Biometrics is that branch of Biology which deals with its data statistically and by mathematical analysis. Using Fingerprints is the oldest method of Identification using biometric information. People have tiny ridges of skin on their fingers. These ridges form through a combination of genetic and environmental factors. The genetic makeup, the position of the fetus in the womb, and the composition and density of surrounding amniotic fluid play a role in how every individual ridge on the skin surface of finger will form. Fingerprints are a unique marker for a person, even an identical twin. Fingerprint analysis can define the differences between two fingerprint impressions.
Human Identity and Individuality: Fingerprints are a unique marker for a person and Fingerprint analysis can define the differences between Fingerprints.
The Fingerprint is electronically read. The corrugated ridges of the skin are non-continuous and form a pattern that has distinguishing features or minutiae. Two varieties of Fingerprint scanning technology are currently used; the optical Fingerprint scanners and the Capacitance Fingerprint scanner that uses a computerized analysis.
Iris Recognition Technology:
Human Identity and Individuality: The Iris is the most unique feature visible on the human body.Iris Scan Recorder uses pattern recognition techniques based on images of the Iris.
Iris Scanners use pattern recognition techniques based on images of the irides (Irises) of an individual’s eyes.
Human Identity and Individuality: How does the multicellular human organism recognizes its own Identity?
No two irides being the same, even in identical twins, individuals could be identified with accuracy and consistency.
DNA Analysis:
Human Identity and Individuality: A small sample of DNA is amplified by using Polymerase Chain Reaction or PCR. The Short Tandem Repeat Analysis examines how often base pairs repeat in specific locations on a DNA strand.
A small sample of DNA is amplified by using Polymerase Chain Reaction or PCR. In a method described as Short Tandem Repeat Analysis, it is examined to find how often base pairs repeat in specific locations or loci on a given DNA strand. These can be dinucleotide, trinucleotide, tetranucleotide, or pentanucleotide repeats; that is repetition of 2, 3, 4, or 5 base pairs. Very often, the investigator looks for tetranucleotide or pentanucleotide repeats in the DNA sample. The likelihood that any two individuals (except identical twins) will have the same 13-loci DNA profile can be as high as 1 in 1 billion or greater.
Biometric Facial Recognition Technology:
Human Identity and Individuality: Every face has numerous distinguishable landmarks, the different peaks and valleys that make up facial features.
Every face has numerous distinguishable landmarks, the different peaks and valleys that make up facial features. These landmarks are known as nodal points. Each human face has approximately 80 nodal points.
Human Identity and Individuality: How does the multicellular human organism recognizes its own identity?
Distance between the eyes, width of the nose, depth of the eye sockets, the shape of the cheekbones, the length of the jawline and other features are used as nodal points. These nodal points are measured creating a numerical code called a face print, representing the face in the database and comparison is made between images of face. 2D or 3D image of a person’s face uses distinct features of the face where rigid tissue and bone is most apparent, such as the curves of the eye socket, nose, and chin to identify the subject.
Human Identity and Individuality. In a multicellular human organism, who recognizes the Identity of the human person?
Unique templates are created from measurements between key points on the face and these measurements provide identification of the individual.
Skin Biometrics – Skin Surface Texture Analysis:
Human Identity and Individuality: The uniqueness of Skin Texture offers an opportunity to identify differences between identical twins.Human Identity and Individuality: Surface Texture Analysis creates a Skin Print by using local information about skin texture at various points on the surface.
The Surface Texture Analysis algorithm operates on the top percentage of results as determined by the Local feature analysis. This method creates a Skin Print and performs either a 1:1 or 1:N match for verification or identification. It can identify the differences between identical twins.
Identity, Individuality, and Consciousness:
Human Identity, Individuality, and Consciousness
Man describes his identity in terms of his personal name, age, gender, race, ethnicity, place of origin, language, religion, political, occupational, or social affiliation. In reality, the man is an association of trillions of individual cells.
Human Identity and Individuality. How does the multicellular human organism recognizes its own Identity?
The human organism is a conscious being and the function called consciousness achieves functional unity of all these individual cells and works for the benefit of the individual who always maintains his individuality.
Human Identity and Individuality. Cognitive Biology must address the issue of cognition of human Identity. In the multicellular human organism, who recognizes the Identity of the Human Individual?
This is possible because individual cells have the ability to recognize the presence of other living cells in their environment and display functional subordination to serve the purpose of the whole organism.
Human Identity, Individuality, and Consciousness – Existence precedes Essence.Whole Foods-Whole Inspiration-Whole LanguageWhole Foods Arrives in Ann Arbor, September 1993Whole Foods opened its Store in Ann Arbor on September 16, 1993. Whole Foods, Whole People and Whole Planet inspire Whole Dude to invent Whole Phrases: Whole Linguistics – Whole Language. The concept of Whole Cookie and Whole Love. Whole Dude uses the phrase Whole Linguistics to describe three entities; 1. Language User, 2. Language Interpreter and 3. Language Creator. Image Credit: Agenda Publications, Ann Arbor District Library, Issue Dates, September 1993, December 1997 and February 1998.
Human Identity and Individuality is defined by the Doctrine of Molecular Individualism
Whole Dude coined the phrase Whole Individualism to discover Man by a study of the building blocks, the structural units and organization of the human body. To defend human existence, Whole Individualism lays the emphasis on knowing the person who is at risk apart from knowing the agent posing the risk.
Whole Dude coined the phrase Whole Individualism to discover Man by a study of the building blocks, the structural units and organization of the human body. To defend human existence, Whole Individualism lays the emphasis on knowing the person who is at risk apart from knowing the agent posing the risk.
The Whole Dude Doctrine of Whole Individualism and Molecular Individualism
THE WHOLE DUDE DOCTRINE OF MOLECULAR INDIVIDUALISM. MAN’S EXISTENCE IS DEFENDED BY MOLECULES CALLED ANTIBODIES WHICH CAN RECOGNIZE OR SEPARATE SELF AND NON-SELF PROTEIN MOLECULES.
Theman exists in the physical world for his existence is essentially supported by Unity or ‘Eikyata’ with ‘Prabhu’, or LORD God Creator. It is of great importance to note that man’s existence involves use of a creative mechanism that deploys unique molecules that establish man’s physical identity on a molecular basis. Man’s existence is ‘Conditioned’ for he has no choice other than that of existing as an Individual with Individuality. This Individualistic Nature of Existence is defended by Immune System that deploys unique molecules called Antibodies.Man’s existence is defended by a creative mechanism that involves deployment of Antibody molecules that distinguish or separate Self and Non-Self.
MENDEL’S LAWS OF INHERITANCE VS HUMAN EVOLUTION: MAN IS ABLE TO EXIST IN NATURE FOR HE IS ABLE TO DEFEND HIS EXISTENCE BY DEPLOYING MOLECULES THAT CAN MAKE THE RECOGNITION AND DISTINCTION BETWEEN SELF AND NON-SELF.SPIRITUALITY SCIENCE-THE ART OF KNOWING: AT A FUNDAMENTAL LEVEL, LIFE AND LIVING IS ABOUT KNOWING MATTER AS SELF OR NON-SELF. THIS IDENTIFICATION OF MATTER INVOLVES THE ABILITY TO RECOGNIZE MOLECULES OF MATTER . TO LEARN THE ART OF KNOWING, MAN HAS TO KNOW ABOUT THE MOLECULAR BASIS FOR EXISTENCE.
Modern Science has provided tools to visually examine large molecules and experimentally verify individualistic variations in their behavior. For this reason, we have to know each man as a Specific Individual with Individuality.
THE WHOLE DUDE DOCTRINE OF MOLECULAR INDIVIDUALISM. DR STEVEN CHU, U.S. SECRETARY DEPARTMENT OF ENERGY DEMONSTRATED INDIVIDUALISTIC BEHAVIOR OF LARGE MOLECULES SUCH AS DNA.The Whole Dude Doctrine of Molecular Individualism. Man exists as an Individual with Individuality. This Individualistic Nature of Existence is defended by Immune System that deploys unique molecules called Antibodies.The Whole Dude Doctrine of Molecular Individualism. Man exists for he is united with Prabhu or LORD God Creator. Man’s existence is defended by a creative mechanism that involves deployment of Antibody molecules that distinguish or separate Self and Non-Self.
Knowing man’s identity and individuality demands understanding of molecules that defend human existence. For example, each antibody molecule bears two identical binding sites consisting of six b-loops.
The Whole Dude Doctrine of Molecular Individualism: At room temperature atoms and molecules in the air move about at breakneck speed. In order for them to be studied, they need to be slowed down or chilled. During the 1980s Steven Chu, Claude Cohen-Tannoudji, and William Phillips developed different methods for this. When atoms come in contact with light particles with fixed energies, photons, their movement is affected as if they had been bumped. With the aid of laser light from different directions and adjustment of the photon’s energy for Doppler effects, the atoms can be cooled to extremely low temperatures and captured in a trap.
Nobel Laureate, Dr. Steven Chu (United States Secretary of Energy), former Professor of Physics and Applied Physics, Stanford University has described that molecules can exhibit a surprising degree of individuality. In experiments that examine the physical behavior of single molecules, Stanford researchers have discovered that identical polymers; long, flexible, spaghetti-like molecules that are found in everything from plastics to living cells; UNFOLD in a variety of ways even when exposed to the same experimental conditions. Dr. Chu had stated : “We discovered it because we have developed the ability to visualize and manipulate single molecules.” He had further observed that, “Only by looking at individual animals you can get a true sense of diversity of species.” Dr. Chu researched Biological Physics and Polymer Physics. Dr. Chu’s research in Polymer Physics made use of individual molecules of DNA to study Polymer Dynamics.
We define our identity in the natural world and defend our existence by deploying unique protein molecules. Our genetic code determines the protein molecules that we use. The genetic code is made up of DNA strands that express Molecular Individualism. It arises from exceedingly small differences in the initial configuration of the polymer.
We define our identity in the natural world and defend our existence by deploying unique protein molecules. Our genetic code determines the protein molecules that we use. The genetic code is made up of DNA strands that express Molecular Individualism. It arises from exceedingly small differences in the initial configuration of the polymer.
Nobel Prize for Medicine Goes to Cancer Therapy
The Whole Dude Doctrine of Molecular Individualism. The Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’. 2018 Nobel Prize for Medicine. My Thoughts on the Molecular Basis for the Defense of Human Existence.
American James Allison and Japan’s Tasuku Honjo have won the 2018 Nobel Prize in Medicine for a pioneering approach to cancer treatment.
The Nobel committee said the pair’s research — which harnesses the body’s immune system to attack cancer cells — amounted to a “landmark in our fight against cancer.” The approach, known as immune checkpoint theory, had “revolutionized cancer treatment and has fundamentally changed the way we view how cancer can be managed,” the committee said.
The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: 2018 Nobel Prize for Medicine. My Thoughts on the Molecular Basis for the Defense of Human Existence.
Image copyright SPL
Two scientists who discovered how to fight cancer using the body’s immune system have won the 2018 Nobel Prize for physiology or medicine.
The work, by Professor James P Allison from the US and Professor Tasuku Honjo from Japan, has led to treatments for advanced, deadly skin cancer.
Immune checkpoint therapy has revolutionized cancer treatment, said the prize-giving Swedish Academy.
Experts say it has proved to be “strikingly effective”.
Prof Allison, of the University of Texas, and Prof Honjo, of Kyoto University, will share the Nobel prize sum of nine million Swedish kronor – about $1.01 million or 870,000 euros.
Accepting the prize, Tasuku Honjo told reporters: “I want to continue my research … so that this immune therapy will save more cancer patients than ever.”
Prof Allison said: “It’s a great, emotional privilege to meet cancer patients who’ve been successfully treated with immune checkpoint blockade. They are living proof of the power of basic science, of following our urge to learn and to understand how things work.”
Treating the untreatable
Our immune system protects us from disease, but it has built-in safeguards to stop it from attacking our own tissue.
The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: 2018 Nobel Prize for Medicine. My Thoughts on the Molecular Basis for the Defense of Human Existence.
Image copyright. Kyoto University. Image caption. Professor Tasuku Honjo and his team at Kyoto University
Some cancers can take advantage of those “brakes” and dodge the attack too.
Allison and Honjo, now both in their 70s, discovered a way to unleash our immune cells to attack tumors by turning off proteins that put the brakes on.
And that led to the development of new drugs which now offer hope to patients with advanced and previously untreatable cancer.
Immune checkpoint therapy is being used by the NHS to treat people with the most serious form of skin cancer, melanoma.
It doesn’t work for everyone, but for some patients it appears to have worked incredibly well, getting rid of the tumor entirely, even after it had started to spread around the body.
Such remarkable results had never been seen before for patients like these.
The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: 2018 Nobel Prize for Medicine. My Thoughts on the Molecular Basis for the Defense of Human Existence.
Image copyright. Getty Images. Image caption. Professor James P Allison
Doctors have also been using the treatment to help some people with advanced lung cancer.
Prof Charles Swanton, from Cancer Research UK, congratulated the prize winners, saying: “Thanks to this groundbreaking work, our own immune system’s innate power against cancer has been realized and harnessed into treatments that continue to save the lives of patients. For cancers such as advanced melanoma, lung, and kidney, these immune-boosting drugs have transformed the outlook for many patients who had run out of options.
“The booming field of immunotherapy that these discoveries have precipitated is still relatively in its infancy, so it’s exciting to consider how this research will progress in the future and what new opportunities will arise.”
My thoughts on the Molecular Basis for the Defense of Human Existence
The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: 2018 Nobel Prize for Medicine. My Thoughts on the Molecular Basis for the Defense of Human Existence.
The Molecular Basis for the Defense of Human Existence. Man’s Unity with Lord God Creator can be learned from the study of Immunology. Each Antibody molecule bears two identical binding sites consisting of six b-Loops.
My ‘Theory of Man’ describes the Man as a Created Being. Man’s physical existence in the natural world in good health or ill-health always demands Man’s Unity (Sanskrit. Asmi) with Lord God Creator (Sanskrit. Brahman) for Man is constituted as a Spiritual Being. Man, the Rational Being is inclined to investigate the basis for the reality of his own existence. The reasoning for my statements is derived from the study of Immunology.
The Defense of Human Existence
The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: The Study of Immune System helps in understanding the Molecular Basis for the Defense of Human Existence.
THE MOLECULAR BASIS FOR THE DEFENSE OF HUMAN EXISTENCE. NATURE OF HUMAN IDENTITY AND INDIVIDUALITY IS REVEALED BY HUMAN DEFENSE MECHANISMS.
An individual exists in the natural world by his biological abilities to defend his continued existence as an independent entity. This essay explores the physiological aspects of human existence and the defensive mechanisms that sustain this existence and the molecules which define and shape our Individualism. The term immunity describes the natural defensive mechanisms that give an individual the ability to recognize foreign proteins and foreign substances and neutralize or degrade them with or without injury to the individual’s own tissues. Immunology is the branch of science concerned with the body’s response to foreign agents and substances.
The Functions of the Immune System
The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: The Functions of the Immune System relate to the role played by unique protein molecules in the Defense of Human Existence.
THE MOLECULAR BASIS FOR THE DEFENSE OF HUMAN EXISTENCE. ORGANS, CELLS, AND PROTEIN MOLECULES OF IMMUNE SYSTEM REPRESENT A CREATIVE MECHANISM TO OPPOSE, NEUTRALIZE, AND DESTROY FOREIGN INVADERS.
The immune system responds to invasion by the foreign organisms and their toxic products. This immune response is also described as active immunity. In the natural world, an infant is defended by molecules transferred passively across the placenta from the mother’s circulation during the fetal stage of development. The infant after birth may also receive passively protein molecules from mother when breastfed. This passive immunity defends the baby for several months and the baby further survives by developing its own immune system. Another major function of the immune system is the removal of damaged or dying cells. The immune system is also able to recognize and eliminate abnormal or mutant cells that frequently arise within the body. Using a system that is described as immune surveillance, the body recognizes and disposes of such abnormal cells which could result in the incidence of certain types of cancer. The immune system plays a vital role in protecting the body from bacteria, viruses, fungi, and parasites and helps to prevent certain types of cancer.
The immune system is very important and it is also very sensitive. The system’s very ability to recognize foreign substances may often result in undesirable reactions. Millions of people suffer on account of hypersensitivity or allergic reactions to fairly harmless substances present in the environment. Many individuals suffer on account of their sensitivity to proteins found in the foods such as milk, eggs, fish, wheat (gluten), and nuts that we consume. Sometimes, the immune system is misdirected and initiates an immune response against the body’s own cells or tissues producing a condition known as an autoimmune disease. While an immune system could cause some problems, we take full advantage of the system to defend ourselves from serious infectious diseases such as smallpox,polio,rabies, diphtheria, whooping-cough, measles, rubella, mumps, tetanus, typhoid, cholera, tuberculosis, hepatitis B, influenza and others by using vaccines and inoculations. Millions of lives are protected by routine use of vaccines and inoculations which help the body to become resistant to these infectious agents. We also use foreign proteins to protect the lives of people in times of a severe life-threatening crisis. We use blood, plasma, and sera (containing immunoglobulins secreted by animals) with utmost care to tide over an emergency. I used foreign immunoglobulins to treat snakebite victims and tetanus cases. The foreign proteins elicit a minor immune response and the situation is carefully monitored.
By being careless and reckless, and by polluting our food, water, air, and soil with dangerous chemicals, we damage our very sensitive immune system and this is contributing to a higher incidence of immune-related health problems in the population.
Types of Immune Response
The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: Man’s Intelligence, mental work, and mental memory are not the “First Line of Defense.”
The Molecular Basis for the Defense of Human Existence: The Fundamental Basis of Human Existence is not that of Man’s Intelligence, Mental Memory and Mental Functions.
The immune system defends human existence with a variety of cells and by the protein molecules known as immunoglobulins or antibodies produced by the immune function capable cells. The ability to recognize foreignness, specificity of the response, and the memory of the prior immune response are the key characteristics of immune defense. The immune system must be able to recognize the foreign agents and foreign materials in order to locate and destroy them. Specificity means that immunity to one foreign substance or organism does not provide resistance to another type of organism. Memory is the ability of the individual to develop an accelerated, enhanced, and long-lasting immunity after the initial attack by an infectious disease. The memory function described in Immunology should not be confused with the mental faculty called Memory. The body defends itself through two types of mechanisms which work together to protect our existence. 1. Humoral Immunity:- this involves the production of protein molecules described as immunoglobulins or antibodies.2. Cell-mediated Immunity:- It does not involve secretion of antibodies but requires direct physical contact with the foreign substance or agent. It also involves the use of other protein molecules which assist in the defense mechanisms.
Humoral Immunity
The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: The recognition of Self and Non-Self at the molecular level is the fundamental basis for human existence.
THE MOLECULAR BASIS FOR DEFENSE OF HUMAN EXISTENCE: HUMORAL IMMUNITY INVOLVES DEPLOYMENT OF UNIQUE PROTEIN MOLECULES TO COUNTERACT WITH FOREIGN PROTEIN MOLECULES.
The cells known as Lymphocytes or B cells are produced in the bone marrow and circulate in our blood and are distributed to the various lymphoid tissues in the body, such as the lymph nodes, spleen, tonsils, and Peyer’s Patches (Lymphoid Follicles) that line the small intestine. When stimulated by an infectious organism, production of lymphocytes increases and the lymphocytes are carried to the site of infection. Depending upon the site of infection, the lymph nodes of that region often swell up and are found packed with lymphocytes. The B cells produce chemical substances known as antibodies. These are protein molecules which are specifically generated against specific organisms. The foreign substance is described as antigen. The antibodies that are generated recognize their antigens with high affinity and extreme selectivity. The interaction of an antigen with its specific antibody involves only small areas on the antigen’s surface; these areas are known as antigenic determinants. Protein molecules are very potent antigens as they have several antigenic determinants. Many carbohydrates are also antigenic because they have antigenic determinants. The antibodies circulate in the blood. The simplest, most prevalent means by which the immune system defends the body against bacteria and viruses is by a combination of a specific antibody with the antigenic determinants on the surface of the invading organism. This interaction between antibodies and antigens produces an aggregate of cells called as an agglutination. The body has wandering scavenger cells known as Macrophages. The clumps of agglutinated cells are engulfed and digested by the macrophages. Antibodies also bind to toxic molecules given off by invading microorganisms and this reaction produces large, insoluble aggregates known as precipitates. These precipitates are also removed by macrophages. The virus after entering the body survives by its ability to invade or enter cells. Antibodies prevent the ability of the virus to infect cells by covering up and blocking the attachment sites of the virus.
Cell-Mediated Immunity
The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: Immunity and Immune Response involves the deployment of unique protein molecules.
THE MOLECULAR BASIS FOR THE DEFENSE OF HUMAN EXISTENCE: INTERACTION OF CELLS AND UNIQUE PROTEIN MOLECULES OF IMMUNE SYSTEM DEFINES MAN’S IDENTITY ON MOLECULAR BASIS.
There is another distinct type of Lymphocytes known as T lymphocytes or T cells. T cells originate in the THYMUS and become localized in lymphoid organs. The immunity associated with T cells does not involve secretion of antibodies but through their direct contact with their targets or by the effects of secreted molecules known as lymphokines which help other cells to make the direct contact. There are four kinds of T cells. 1. The cytotoxic T cells or Natural Killer cells or NK cells defend the body by destroying infected, foreign or cancerous cells. The other three kinds of T cells regulate immune responses by secreting messenger proteins known as lymphokines. 2. Helper T cells enable the other T cells and most B cells to perform their functions. The Helper T cells are destroyed by Human Immunodeficiency Virus (HIV) in Acquired Immune Deficiency Syndrome (AIDS) patients resulting in a depressed immune response that allows infection by a variety of microorganisms and the growth of some types of cancerous tumors. AIDS patients are very vulnerable to fatal infections. 3. Suppressor T cells dampen the immune response of the B and T cells. 4. The fourth kind of T cell is involved in certain kinds of hypersensitivity reactions. In a normal healthy individual, there is a balanced ratio of these four kinds of T cells to provide an efficient immune system for defense against all foreign substances. Macrophages and White blood cells known as neutrophils have the ability to engulf and digest particulate matter by the process of phagocytosis. They eliminate many foreign organisms and particulate materials that enter the body. The ability of NK cells to kill or destroy some cancerous or tumor cells is enhanced by two lymphokines known as gamma interferon and interleukin-1. Another lymphokine known as interleukin-2 activates the Lymphokine Activated Killer Cells or LAK cells which also have the ability to kill a variety of human tumor cells. Activated T cells also secrete a lymphokine known as Transfer Factor which is able to cause normal lymphocytes to release lymphokines or otherwise become activated and thus to destroy other cells. Transfer Factor stimulates the lymphocytes to develop normal immunity.
The Cytotoxic T cells destroy other cells by interacting with antigens present on the surfaces of the cell. They are involved in the attacks on tissues and organs grafted or introduced into the body, viral antigens found on infected cells and on chemicals that have entered the body and found attached to cells. T cells are involved in skin reactions resulting from contact with molecules found in poisonous plants like Poison Ivy, Poison Sumac, and Poison Oak.
Organ Transplantation and Cell-Mediated Immunity
The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: Identity and Individuality are determined by unique protein molecules of the human body.
THE MOLECULAR BASIS FOR THE DEFENSE OF HUMAN EXISTENCE: ORGAN TRANSPLANTATION AND IMMUNOLOGY. MOLECULES OF HISTOCOMPATIBILITY LEUKOCYTE ANTIGEN (HLA) SYSTEM
T cells are involved in the rejection of transplanted tissues and organs. The chances of successful organ transplantation are improved by carefully matching the tissue or Histocompatibility Leukocyte Antigens known as the HLA system of the donor with those of the recipient. The protein molecules of the HLA Complex establish the identity of our body, its tissues, and various organs. They work to preserve the identity of the individual and to exclude the introduction or grafting of foreign material into the body. Even after careful matching, and selection of suitable donors, transplanted tissues or organs are usually maintained by using drugs that cause immunosuppression by which the normal immune response of the recipient against the donated organ is prevented.
Biological Existence
A normal, healthy immune system is vital to defend our biological existence. Immunodeficiency diseases, depressed or compromised immune system conditions such as associated with corticosteroid therapy, chemotherapy, radiation therapy, or exposure to certain types of toxic chemicals, and autoimmune diseases impose a heavy burden and threaten our existence. Medical interventions and treatment may help us but the quality of life is invariably compromised. A functioning immune system is important to defend our existence.
Molecular Individualism
The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’: Immunology helps in understanding the Molecular Basis for Man’s Identity and Individuality.
The Molecular Basis for the Defense of Human Existence: Man exists as Individual with Individuality as his existence involves defensive mechanisms operated by independent, individual cells, and protein molecules which exhibit Cellular Autonomy. The cell is the lowest common denominator of all life. While the cell is functionally independent or autonomous or self-governing, it displays the abilities characterized by Mutal Assistance, Cooperation, Tolerance, and Functional Subservience to provide some benefit to the Individual who lives in the physical world.
2018 Nobel Prize for Medicine will help us to develop a ‘Theory of Man’ by the study of unique protein molecules that play an important role in the defense of human survival. The Physical Being called Man needs the support of Spirit, Soul, or a Divine Agency to bring Unity between the cells, tissues, organs, and organ systems providing the structural and functional basis for Man’s existence.
The Whole Dude Doctrine of Molecular Individualism. Study of Antibody Molecules will help in understanding the concept of ‘Molecular Individualism’. The Doctrine of Individualism. The Man has no choice other than that of existing as an Individual with Individuality. His genome is unique and one of its own kind.Michigan Medicine should have known better and must use valid, verified principles to identify every Human Being as a Specific Individual with Individuality without depending upon unverified claims about Race and Ethnicity.
The Whole Dude Concept of Whole Spirituality begins with the Building Blocks of Life
Whole Foods-Whole Inspiration-Whole LanguageWhole Foods Arrives in Ann Arbor, September 1993Whole Foods opened its Store in Ann Arbor on September 16, 1993. Whole Foods, Whole People and Whole Planet inspire Whole Dude to invent Whole Phrases: Whole Linguistics – Whole Language. The concept of Whole Cookie and Whole Love. Whole Dude uses the phrase Whole Linguistics to describe three entities; 1. Language User, 2. Language Interpreter and 3. Language Creator. Image Credit: Agenda Publications, Ann Arbor District Library, Issue Dates, September 1993, December 1997 and February 1998.The understanding of cancer leads to the understanding of the spiritual substance of the cell.Whole Dude at Whole Foods applies the principles of Cytology to study the spiritual substance of Cancer Cells and Normal Cells. This is the most detailed model of a human cell ever created, built using real scientific data from X-ray crystallography, NMR, and cryo-electron microscopy. Titled “Cellular landscape cross-section through a eukaryotic cell,” this stunning visualization by Evan Ingersoll and Gael McGill reveals the densely packed, molecular complexity of life at the nanoscale.Whole Dude at Whole Foods applies the principles of Cytology to study the spiritual substance of Cancer Cells and Normal Cells. Whole Dude at Whole Foods. The Discovery of Whole Spirituality at Whole Foods, Ann Arbor. The Bone Marrow smear from a patient of Leukemia or Blood Cancer helps to illustrate the nature of Biotic Interactions in the Social Group or Biotic Community that represents the singularity called man. The true or real man can only be discovered by the microscopic study of the Cells that constitute the Organism.
National Cancer Act of 1971:
Whole Dude at Whole Foods applies the principles of Cytology to study the spiritual substance of Cancer Cells and Normal Cells The understanding of cancer leads to the understanding of the spiritual substance of the cell.
On December 23, 1971 President Richard Nixon signed the National Cancer Act to direct efforts to conquer the problem of cancer through investment in cancer research and biomedical science. After about 50 years of the signing of the National Cancer Act, we need to reflect upon the problem of cancer. The study of cancerous cell will help us to give our attention to the spiritual substance of the cell whose composition resists the changes caused by cancer which disrupts all other living functions of the cell.
Whole Dude at Whole Foods applies the principles of Cytology to study the spiritual substance of Cancer Cells and Normal Cells. The understanding of cancer leads to the understanding of the spiritual substance of the cell.
Cancer begins with a single mishap or mutation within the nucleus where 23 pairs of chromosomes on which 20,000 to 25,000 genes are scattered. Genes hold the instructions for regulating a variety of cell functions, and proteins carry out the instructions to perform these cell functions.
Whole Dude at Whole Foods applies the principles of Cytology to study the spiritual substance of Cancer Cells and Normal Cells. The understanding of cancer leads to the understanding of the spiritual substance of the cell.
Cancer is a problem associated with abnormal cell proliferation or cell divisions. Cancer study helps us to understand normal functions of cells and to learn about the instructions that tell the cells to grow or to stop growing to make new cells. Normally, cell division begins in response to a signal or instruction received. Cells have circuits or pathways to send instructions. Genes send signals to each other along pathways. When a cancerous cell divides, the new cells receive signals to continue proliferation or cell divisions with the characteristics of immortality. The immune surveillance system may detect the presence of cancerous cells by detecting unique surface marker proteins present on the surface of the cancerous cells and the cells of the immune system neutralize or kill the cancerous cells. The study of cancer provides insight into individual signaling pathways and mutations that are characteristic of cancer.
Whole Dude at Whole Foods applies the principles of Cytology to study the spiritual substance of Cancer Cells and Normal Cells. The understanding of cancer leads to the understanding of the spiritual substance of the cell.
The diagnosis of cancer involves the identification of the cells involved, and their location in the body. For each type of cancer disease, there are many genetic variants. Each cancer has to be defined by knowing the genetic mutation that has affected the individual cell. For example, currently, cancer researchers have identified about 56 sub-types of non-Hodgkin lymphoma. Each sub-type has its own genetic signature. Cancer treatment involves the killing of cancer cells and the therapy may often cause damage or death of healthy cells and tissues. Cancer research is developing targeted therapies that specifically address cellular flaws and spare the normal, and healthy cells, and tissues.
Whole Dude at Whole Foods applies the principles of Cytology to study the spiritual substance of Cancer Cells and Normal Cells. The understanding of cancer leads to the understanding of the spiritual substance of the cell.
Cancer and the theory of human nature:
The understanding of the problem of cancer would help us to answer the question: “What is Man?” We need to know and understand man if we have to fight the problem of cancer. Man is an organism represented by a biotic community of about 100 trillion individual living cells and ten times more of other living organisms that inhabit his gastrointestinal tract. The problem of cancer involves the study of the nature of biotic interactions among members of this biological community. If the members, the individual living cells interact in a manner that show characteristics such as mutual assistance, cooperation, sympathy, understanding, devotion, and functional subservience, man will keep his biological existence and the quality of this existence becomes an attribute of his health and well-being.
Whole Dude at Whole Foods applies the principles of Cytology to study the spiritual substance of Cancer Cells and Normal Cells. The integration of Structure and Function describes the Spiritual Basis for Health and Human Existence. By knowing the structure and function of the Red Blood Cell or Erythrocyte, we can establish the facts of Blood Circulation, the reason for the structure of the Heart and Lungs, their motions and their relation to each other and their relation to the Human Being who exists as an Individual with Individuality.
In this context of studying the nature of the Cancerous Cell, Whole Dude defines the word ‘Spiritualism’ as mutually beneficial interactions between individual living cells of the human organism and the Whole Organism represented by the singularity called man. For example, the Red Blood Cells deliver Oxygen and remove waste products from other cells in the human body displaying the characteristics of a spiritual relationship or partnership. In the problem of cancer, we encounter cancerous cells that fail to display the chracteristics that I have mentioned. The cancer cells behave like an internal enemy; they invade the territory or space of normal and healthy cells and tissues. Cancer grows and causes both structural and functional changes in the tissues and organs where it is located. The cancer cells show the propensity to spread or invade the local and distant parts and sites of the body apart from occupying the place of their origin. Most of our medical interventions aim at destroying these enemy cells that threaten the biological existence of the cancer victim. The cancer variants describe the genetic variations found in the nuclei of cancerous cells and not that of any variation in the cytoplasm of these cells. This corporeal substance found inside the living cells is ‘spiritual’ in its nature where the word ‘spirit’ means the potential for immortality, imperishability, and immutability. This spiritual substance remains unchanged while the cancer disease affects the genes altering the structure and function of genes to deliver normal instructions. Man always comes into existence from a previously existing egg cell and inherits the maternal cytoplasm. Man survives because of the spiritual nature of this inherited maternal cytoplasm. Hence cancer research must explore the spiritual nature of man that has the potential to survive from generation to generation.
Joy in Life, Love and Compassion in Heart:
Whole Dude at Whole Foods applies the principles of Cytology to study the spiritual substance of Cancer Cells and Normal Cells. The understanding of cancer leads to the understanding of the spiritual substance of the cell.
The spiritual well-being of man is reflected as joy in life, love, and compassion in heart. In health care, the term ‘comprehensive care’ describes the preventive, the diagnostic, the curative, the rehabilitative, and the restorative care of the entire person and not merely treating the symptoms of the disease. Cancer like several other disease entities imposes stress upon the human organism. The fear of premature death, the fear of disability or disfigurement, the risks imposed by chemotherapy, radiation, or surgery, the medical costs, and the loss of employment or of employability contribute to psychogenic stress. The human body is further exposed to physical and chemical stress because of the nature of medical interventions. Cancer as a disease causes ‘biotic stress’. The cells of the immune defense mechanism may detect the presence of cancerous cells and initiate a battle to destroy them. This immune response causes internal stress and very often there is no cortical awareness of this inner battle to defend life. The hostile biotic interactions between cancer cells and healthy cells produces a stress reaction which is mediated by the same stress pathways; the hypothalamic-pituitary-adrenal pathway. A cancer victim would have a better chance to become a cancer survivor if he is stress resistant and has greater stress tolerance. The restorative care in cancer patients must commence as soon as the diagnosis of cancer is made as the body has already experienced the stress reaction before the clinical diagnosis of cancer is made. The understanding of the spiritual nature of man will offer tools to promote stress tolerance and stress resistance.
Man is a Spiritual Being:
The understanding of cancer leads to the understanding of the spiritual substance of the cell. The Banyan Tree inspires the study of imperishable substance.Adhyatma Vidya. The Knowledge of the Spiritual Self. The Great Banyan Tree of Kolkata has lived for over 250 years. This tropical fig tree known as Ficus benghalensis is native to India; ‘adventitious’ roots that grow from its branches go downwards and take root to form new trunks over a relatively wide area. In the Sanskrit language, the Sacred Fig or Ficus religiosa is known as ‘ASVATTHA’. In my opinion, Hindu Scriptures refer to Banyan tree as ‘ASVATTHA’. It is cherished for its everlasting or imperishable nature. If the tree is living, we need to know the nature of its substance that keeps it living.The Banyan Tree presents a peculiar appearance for it has the ability to spread over an extensive area with the help of adventitious roots that grow towards earth from its branches spreading upwards and outwards. The growth and spread of the Banyan Tree is unlike the growth and spread of cancer which serves no purpose.
The Knowledge of The Banyan Tree:
The understanding of cancer leads to the understanding of the spiritual substance of the cell.
The Hindu Scripture of The Bhagavad Gita, Chapter XV known as Purusottama Yoga speaks about the nature of the Supreme Person. It metaphorically compares the Supreme Being to the popularly known Fig Tree called Ficus benghalensis. The first verse reads as follows:
The Supreme Lord Krishna said: There is a Banyan Tree which has its roots upwards and its branches down and metaphorically it is imperishable; and the Vedic hymns are its leaves. One who knows this Tree is the Knower of the Vedas (the person attains the Knowledge of the Ultimate Reality or the Supreme being).
The understanding of cancer leads to the understanding of the spiritual substance of the cell.
When we know the Banyan Tree and its apparent imperishable quality, we may understand the true nature of Man. Man is a spiritual being. The truth or falsity of this proposition depends on the fact of man’s having a substance that is of spiritual nature. Such a substance of spiritual kind is perceptible to the senses, is amenable to direct observation, and could be subjected to verification by experimental science. To establish the fact of man’s spiritual nature, it needs reasoning based upon scientific validity.
The structure and the behavior of things contribute to their individual being and function. If man has a set of defining features based upon his structure (Human Anatomy), function (Human Physiology), and behavior (Human Behavioral Science), the spiritual nature of man could be proved on theoretical and practical grounds and could be verified by scientific experiments. I am not seeking to discover a soul or spirit that could have existence independent of man’s physical being. However, it will be important to note that it is not possible to conceive of a soul or spirit if it is never associated with its human body. My purpose is that of describing the spiritual nature of human organism and of other living beings. To understand the true nature of human being, we need to ascertain the validity of Knowledge that pertains to the Spiritual Self.
Man is a Mortal Being:
Man is a mortal being who must eventually die. When Lazarus died and was laid in a tomb for four days, Jesus performed a miracle and Lazarus came back to life from death. The Book of John, Chapter 11, narrates this event. In verses 41 and 42, Jesus said,”Father, I thank You that You have heard Me. And I know that You always hear Me, but I said this for the benefit of the people who are standing here, that they may believe that You sent Me.” The risen Lazarus had eventually died.
Man’s greatest need is not only to know the world around him but also to know himself better. Man must understand what it is to be a substance and what it is to exist. Man is a physical being or thing with matter and form. The corporeal body of man is composite of two principles; matter, and form. What is called matter is potentiality, and what is called form is actuality. The corporeal substance called protoplasm becomes actuality and is recognized as a living person because of the uniqueness of its genome that operates its living functions and defines its size, shape, color, and external form or morphological appearance. However, life comes into existence only when matter or substance has the ability to acquire energy from its external environment. The human being comes to life when his corporeal substance uses its potential ability and power called ‘Nutrition’ to acquire energy and material from its environment.
The Journey of the Egg Cell. The event called conception or fertilization must be followed by an event called implantation to sustain the life of the embryo and the growth and development of the fetus.
Life begins with fertilization, the union of sperm with egg cell, and this event called conception proceeds to develop a human being after an important event called implantation. The life journey after conception continues if there is a connection between the energy seeking embryo and its maternal energy provider. To exist means that the substance is maintaining a relationship, a partnership, a connection, or association with its source of energy.
Man leads energy dependent existence deriving energy and material from nature which supports other living forms with a similar corporeal substance called protoplasm. The mortality of man must be understood as the dissolution of man’s physical form. The dissolution of living man into non-living molecules and physical elements would not alter that potentiality of protoplasm to acquire energy and material to create its own substance.
Things in Nature change with Time; but what is called Nature remains unchanged even under the influence of Time. As per The Laws of Conservation of Mass and Energy as described in classical Physics, mass or energy remain constant. The potentiality of living substance to acquire energy and material to form its own kind of substance has remained unchanged or unaffected by major natural calamities and other cataclysmic events. Life forms perish and yet life continues as new life forms. During the billions of years of existence, planet Earth has experienced several minor, and major Extinction Events described in its geological history.
The Science of Paleontology offers scientific evidence to support an argument based upon theoretical and practical grounds to propose that the substance called protoplasm could be eternal, immovable, immutable, and indestructible. At a fundamental level, it could be stated that man is a mortal or materialistic being who derives his physical form because of its association with an imperishable substance. During any stage of his existence, the form called man cannot be separated from the eternal nature of its substance.
The relationship between Matter and Form:
The understanding of cancer leads to the understanding of the spiritual substance of the cell. The relationship between Matter and Form. Adhyatma Vidya. The Knowledge of the Spiritual Self. California State Tree known as Redwood includes Sequoia sempervirens and the Giant Sequoia is known as Sequoia gigantea. The Redwoods are the most massive trees in the world and could attain a trunk diameter as large as 30 feet. They also include the tallest trees in the world averaging about 300 feet high. They include the oldest known living trees and may reach ages of over 3,000 years. What is that corporeal substance that is living apparently in an imperishable manner?Sequoia sempevirens. Man has officially designated this tree as the State Tree of California State. What is the connection between Man and Plants or Trees? What is the corporeal substance shared or common to all living entities?Adhyatma Vidya. The Knowledge of the Spiritual Self. Sequoia gigantea is a massive tree. A living thing has a form and has matter. We often recognize the form and give it a name. What about the “MATTER” that constitutes the substance of this living thing? We need to understand the ‘potentiality’ of the Matter to know the nature of the Form. The Form has no independent existence of its own. The Form lives if and only if it has Matter that is living.
What is Soul or Spirit ?
The Book of Genesis, Chapter 1, verse 27:”So God created man in His own image; in the image of God He created him; male and female He created them.”
Traditionally, man has been divided into two parts; body, and soul. In common usage, the term soul represents the immaterial aspect of a human being. Soul is further defined as that part of the individual which is considered to survive the death of the body. The term spirit is often used to describe a disembodied soul. On separation from the human body, the soul or spirit has a life of its own, a capacity for independent existence or self-subsistence which describes its immortality.
The Conceptions of Soul:
There are a variety of conceptions about soul or spirit. Some of the traditional conceptions of soul are the following:
1. Soul is the immaterial substance, form, or principle of self-motion, vitality, life force, or life in living things. The insentient body is completely distinct from the sentient soul.
2. Soul describes the Doctrine of the Self, and is considered to be synonymous with the True-Self. In a human being, soul confers the Individuality and its nature of humanity.
3. Soul is often described as a thinking substance and is equated with mind. The soul has knowledge of itself by reflection of its acts. The soul is the knower and it knows the physical, and mental acts of the human body where it resides.
4. Soul is important to maintain, and to preserve life. Soul may not directly participate in the activities of the human body. However, the activities of the human body may have a polluting effect on soul. If the soul is tainted or contaminated by the sinful acts of the body, the soul may obtain purification by its release from the body. Some form of human effort, activity, attitude, and behavior is essential to keep the soul in its natural, pure, and perfect condition.
5. The soul that has experienced the polluting effects by its association with a human body would be forced to experience perpetual reincarnation by a process called transmigration. The soul continues to reside as a prisoner in different bodies until such time it attains its original state or condition of purity and perfection.
6. Soul is a transcendental or noumenal object that is real but not visible and could not be detected by human sensory perception. The human body that is visible is in fact unreal or is a product of sensory illusion.
I ask my readers to attach a simple meaning to terms such as the soul or the spirit. It would be sufficient to describe the soul or the spirit as the vital, animating principle found in all living things.
The relationship between Soul and human body:
Most religions and cultures speak about soul and describe it as some incorporeal or immaterial substance/principle of human life that is distinct from the body. Despite the frequent acceptance of the existence of a soul, different religions and philosophers have developed a variety of theories as to the nature of the soul and its relationship to the human body. There are divergent views about the origin of the soul, when and how it gets implanted into the human body, and the mortality or when and if the soul dies. I would like to share the view that is attributed to Lord Krishna, the avatar or reincarnation of Hindu God Lord Vishnu.
Adhyatma Vidya – The Knowledge of Spiritual Self – The teachings of the Bhagavad Gita
SPIRITUALITY SCIENCE – THE KNOWER – THE KNOWING SELF : INDIAN TRADITION AND OTHER TRADITIONS OF WORLD DO NOT DESCRIBE THE PRECISE ANATOMICAL LOCATION OF SPIRIT, SOUL, OR ATMAN. THIS IMAGE DESCRIBES THE HIERARCHAL RELATIONSHIPS THAT MANAGE MAN’S MENTAL FUNCTIONS.
The word ‘vidya’ relates to acquired knowledge or learned experience derived from studies and teachings imparted by an instructor. The term ‘adhyatma’ pertains to the individual soul, atma, or atman which describes the Spiritual Self. The phrase ‘Adhyatma Vidya’ could be described as the Knowledge of the Spiritual Self.
The legendary IndianSage Veda Vyasa also known as Krishna Dvaipayana was the author of the epic poem The Mahabharata (Great Epic of the Bharata Dynasty). Veda Vyasa is recognized as the compiler of ancient Hindu texts known as Vedas. In the Book VI of Mahabharata, Lord Krishna converses with Prince Arjuna while the warring parties of Pandavas, and Kauravas face off each other at the battlefield of Kurukshetra. Lord Krishna reveals His views about soul, human body and their relationship in “The Song of the Lord” known as ‘The Bhagavad Gita’. These poems of The Bhagavad Gita give a synopsis of the religious thought and experience of India through the ages.
The understanding of cancer leads to the understanding of the spiritual substance of the cell.
The Chapter X of The Bhagavad Gita is titled ‘Vibhuti-Vistara Yoga’ and it describes the divine or transcendental attributes of the Supreme Lord. In verse 39, the Lord claims, “I am the generating seed of all existences. There is no being, moving or unmoving (Chara-acharam) that can exist without Me.”
O Arjun, know Me to be the beginning, middle, and end of all creation. Amongst sciences I am the science of spirituality, and in debates I am the logical conclusion.
The understanding of cancer leads to the understanding of the spiritual substance of the cell.
In verse 32, the Lord proclaims, “….of all the branches of Learning and Knowledge, I am the Knowledge of the Spiritual Self (Adhyatma Vidya).
I am the Samaveda amongst the Vedas, and Indra amongst the celestial gods. Amongst the senses I am the mind; amongst the living beings I am consciousness.
The understanding of cancer leads to the understanding of the spiritual substance of the cell.
In verse 22, the Lord describes the nature of His connection with the living beings that He creates, “…. and in living beings, I am Consciousness (Bhutanam asmi Chetana).” He also clarifies that Consciousness or Chetana is a different characteristic and separates consciousness from mental functions and mental activities such as thinking skills, intellectual abilities, and sense perception. Mind is traditionally viewed as the major organ of sense perception, seat of thoughts, intellect, emotions, feelings, and self-ego. Chetana is associated with the fundamental living characteristics of a living thing.
The Lord also cites The Vedanata Sutra to make the distinction between the body, the soul, and the Supersoul. The Vedanta, the insights from Vedic Scriptures describe three manifestations of the Supreme Lord’s Energy. These are 1. Annamoya or dependence upon Food for existence, 2. Pranamoya or the manifestation of the living symptoms and life forms, and 3. Jnanamoya or the Knowledge of the distinction between the body the field of activity and the Knower who resides in the body. If a living being needs food for its existence, and performs its living functions in a state or condition called awareness or consciousness, it could be described as the manifestation of the Supreme Lord’s Energy.
I am the pure fragrance of the Earth, and the brilliance in fire. I am the life-force in all beings, and the penance of the ascetics.
The understanding of cancer leads to the understanding of the spiritual substance of the cell.
In Chapter VII titled ‘Paramahamsa Vijnana Yoga’ or Knowledge of the Ultimate Truth, in verse 9 Lord Krishna claims: “I am the life force (Jivanam) of all that lives.” He demonstrates a connection between life and consciousness to describe the spiritual nature of Self.
kṣhetra-jñaṁ chāpi māṁ viddhi sarva-kṣhetreṣhu bhārata kṣhetra-kṣhetrajñayor jñānaṁ yat taj jñānaṁ mataṁ mama
The understanding of cancer leads to the understanding of the spiritual substance of the cell.
The Chapter XIII of The Bhagavad Gita titled ‘Kshetra – Kshetrajna Vibhaga Yoga’ deals with the dichotomy or distinction between the material body, immortal soul, and the Supersoul. It states the view that the material body is called the field of activity or Kshetra. One who knows this body, the field of activity is called the Knower of the Field or Kshetrajna. The Knower of the Field is the Owner of the body. The Supreme Lord is also the Knower of the field of activity in all bodies (verse 3).
Adhyatma Vidya. The Knowledge of the Spiritual Self. Body, Soul, and the Supersoul.The understanding of cancer leads to the understanding of the spiritual substance of the cell.
In this human body, there is another indwelling obeserver, a sanctioner, a preserver, an enjoyer, and indeed ultimate Controller called ‘Paramatama’ or Supersoul. The Supreme Lord or Paramesvaram is residing equally in all living entities (verses 23, 27, and 28 ).
The understanding of cancer leads to the understanding of the spiritual substance of the cell.
Just like the Sun who illuminates the entire living world, the soul within the body illuminates the entire field of activity of the physical body by Chetana or Consciousness (verse 34). This view as stated suggests that consciousness is the proof or the symptom of the presence of the soul.
The understanding of cancer leads to the understanding of the spiritual substance of the cell.
A similar view is shared in Chapter II titled ‘Sankhya Yoga’. The imperishable or indestructible soul pervades or permeates (tatam) the entire physical body (verse 17). What is spread all over the body?
Adhyatma Vidya. The Knowledge of the Spiritual Self: Existence Precedes Essence.
Consciousness could be described as spread over the entire body and it leads to the interpretation that the symptom of the soul’s presence is perceived as individual consciousness.
The understanding of cancer leads to the understanding of the spiritual substance of the cell.
The final Chapter XVIII of The Bhagavad Gita titled ‘Moksha-Opadesa Yoga’ comes to an interesting conclusion about the Single Reality that pervades all existence that is divided into innumerable forms. Verse 20 reads as follows:
“Understand that Knowledge by which one undivided, imperishable (Avyayam) reality is seen within all diverse living entities is in the nature of goodness (Sattvikam).”
What is that undivided reality that is imperishable that connects all the diverse, living entities?
The Body-Soul dichotomy:
In the Indian tradition, the individual soul is known as Atma or Atman. The Supreme Soul or the Supersoul is known as Paramatma, Paramesvaram, or Brahaman, the Ultimate Truth and the Reality. However, the concepts about Atma or individual soul vary and Hindus belong to different schools of thought. While the concepts about individual soul are different, there is general agreement among various Indian thinkers and philosophers about the distinction between the material, insentient, and perishable human body and the immaterial, sentient, and imperishable or immortal soul. Soul is independent, and is not attached and it still requires the substance of the corporeal body. However, I am not able to draw that distinction and make that separation from the substance and its function. To describe function, I need the substance. Man lives and functions with consciousness because of the fundamental nature of the corporeal substance called protoplasm, and this substance is apparently imperishable, indestructible, and immortal. We could destroy the physical form of man and of several other living forms, but man or nature and the influence of Time have not demonstrated an ability to destroy this living substance which has survived on planet Earth continuously over billions of years. Man cannot create life and man cannot destroy life. Man can only live or exist because of the spiritual nature of his corporeal substance with which he can not seek separation until the time of his death. The substance has a life of its own and continues to create new substance of its own kind and becomes visible as a living life form with a different identity or morphological appearance.
Matter, Energy, and Knowledge:
The Greek philosopher Aristotle observes that corporeal substances are composite of two principles, form and matter. What is called matter is a potentiality, what is called form is an actuality. The totality of things has been divided in various ways. The three fundamental distinctions are 1. the distinction between the natural and the supernatural, 2. the distinction between the material and the spiritual, and 3. the distinction between the lifeless and the living. When we make the distinction animate/inanimate, living/non-living, and inorganic/organic, a question arises about the nature of that distinction. The difference, is that one of kind or degree? The Mechanistic View claims the continuity of nature in terms of the universality of purely mechanical principles.
I define Life as the organization of matter with implanted supernatural Knowledge. The establishment of supernatural Knowledge in matter describes the operation of ‘God Principle’, Spirit, or Soul. Life comes into existence when matter and energy come together with the establishment of ‘God Connection’.
At a cellular level, the social function is called ‘Association’. Man is an association of trillions of cells. Each human organ and organ system represents an association of cells that display functional subordination to perform selective tasks. Life is just impossible without social structure and organization.
Life and Consciousness:
The Ground Substance of Spiritualism and Spirituality. The vital characteristics, the animating principles of Protoplasm could be known by observing Amoeba proteus. The Living Substance works as an organ of Motion or Movement, as an organ of Nutrition, and as an organ of Reproduction to generate new cells which have a life span of their own. In these physiological functions, I describe the characteristics such as Cognition, Consciousness, Memory, and Intelligence which have a Spiritual role as they bring functional unity and harmony in the interactions between different parts of the same individual organism while it exists in an environment as a member of a biological community.
The basic characteristic of a Living Cell or organism is the presence of consciousness. I recognize a cell as a Living Cell if it displays functions that characterize the presence of awareness or consciousness. The Living Cell or Living Object need not be aware or conscious of the Subject who may be investigating or observing the properties of that Object. The Living Object need to be aware of its own existence and its condition called Living. Atoms and molecules display their properties and interact according to the Laws of Physics and Chemistry. Living organic molecules show individualistic behaviors under experimental conditions that could be repeated and be verified. The Living Cell is very selective and it responds in a variable manner to physical and chemical stimuli. It can communicate or send signals to other Living Cells present in its environment. It responds according to its internal condition in relation to the environment in which it exists. The interactions of non-living physical matter are not goal-oriented. The interactions of Living matter are goal-oriented and they specifically achieve the purpose of sustaining, preserving, defending, and continuing the Living functions.
Life and Death is a Continuous Process:
When does Life begin? When does Life end? Life always comes into a state of existence from a previously existing Living Cell. Life and Death is a continuous process and is recognized by the presence of Consciousness and Individuality.
When does Life begins? When does Life ends? Every Living Cell is derived from a previously existing Living Cell. Life has not experienced the final event called DEATH. Life continues its act of Living through a function called Reproduction. A given species is considered to be totally extinct only if there is no surviving member to represent that particular species. Death is a programmed event and it gives meaning to the Identity of a Living Object. The dissolution of a single Living Object should not obscure the fact that Life is a continuous process.
Life continues as Living Objects get new Identities. It is very reasonable to expect that Life would continue after the death of a given Living Object. People all over the world are a witness to that simple and direct observation. During the Life-Death continuum, the connection between the Creator and the created Living Object is manifested by the biological function called awareness or consciousness. The presence of Soul is evidenced by the presence of consciousness. As long as the Soul is functioning and is united with the physical being, the presence of consciousness could be detected and could be verified.
The Soul and God Connection:
The understanding of cancer leads to the understanding of the spiritual substance of the cell.
There has been no clearly defined and universally accepted metaphysical conception of the term Soul. It is a term rarely used with precise definition in philosophy, religion, or common life. In this discussion we face the problem of using words to which no definitive meaning is attached. If I make an attempt to define the word ‘God’, you may even speculate that I may belong to a new religious order. We need to come to a consensus even if an entity called ‘God’ does not exist. We need to formulate a view, a hypothetical view about Soul and test that hypothesis by countering it with a skeptical hypothesis. The Science called Physics deals with the properties, changes, interactions, etc. of matter and energy in which energy is considered to be continuous. In the ultimate analysis, matter is a representation of its energy content. The Science called Biology deals with Life and Life processes. While Life is made up of physical matter, Life processes are not explained by simple mechanistic interactions. However, I am willing to use the principles, the methods, and the tools used by Physics. Molecular Biology explains biological events by studying the molecules within cells; the molecular basis of genetics – Nucleic Acids and its relationship to energy cycling and replication. If this universe is seen as matter and energy, I would define God as the Controller of Force/Power/Energy. All living things are essentially made up of the same kind of living matter and yet they appear to be different. Life could be attributed to ONE common principle which has the ability to be simultaneously different. Each living object comes into a state of existence as a new object, as an original object, one of its own kind, unique, and distinctive. This morphological variation is an attribute of the organic molecules that establish the phenotype or the physical identity of that living organism. Physics provides those powerful tools to see the molecules and to recognize their individualistic behavior. Life comes into existence using a creative principle, and creative mechanisms that need inspiration, and imagination apart from the use of simple mechanistic laws. If Life is governed by the Law of Individuality, I would define God as a Creative Force/Power/Energy.
The understanding of cancer leads to the understanding of the spiritual substance of the cell.
A majority of these life forms that we know and have studied, have synchronized their state of existence with an event that produces alternating periods of light and darkness while that source of light is not being turned ‘on’ and ‘off’. Rather we are forced to experience the effects of an illusion. Sunrise and Sunset is the reality that governs a majority of Biological Rhythms that control the life processes. Illusion is the necessary condition for the biological existence of Life. If Earth’s rotational spin generates this illusion, God uses Force/Power/Energy to cause illusion. In the universe that exists today, to the extent we have verified; there are no two identical celestial objects that exhibit the same rotational spin. In this context, it may be said that the Force/Power/Energy called God has created Earth to provide a home to the life forms that He has created as Individuals. These life forms have the ability called reproduction and yet lack the ability of producing two identical new objects. Sexual or Asexual reproduction always results in the production of new Individuals which could be easily verified by using the Biometric Identification Technology. Even the clones, sharing identical genomes, in reality exist as individuals. This Individuality when investigated by the tools supplied by Physics, it is discovered that the organic molecules behave as Individuals and man is not able to modify that behavior. Under the same experimental conditions, the molecules behave as individuals. When we examine the nature of this biological existence, it indicates that life processes are supported by the provision of energy from an external source. The Living Cell is a thermodynamically unstable system. This means that without a continuous input of energy a Living Cell will degrade spontaneously into a nonliving collection of molecules. This lack of energy independence would direct us to define God as the Power/Force/Energy which delivers Compassion/Mercy/Grace which helps energy acquisition by energy dependent living organisms. Life forms on planet Earth exist depending upon an extraterrestrial source of energy or Cosmic Power/Force/Energy. Life exists because of its ability called ‘Association’. The act of associating, the state of being associated; the companionship, the fellowship, and the partnership is the defining feature of the State or Condition, or Act of Living. Association or patnership between energy seeker and energy provider could be described as God-Connection. Organisms that are single do not live as single cells but develop association with other single cells to form distinct Colonies. Organisms that are multicellular represent an organization of individual cells that are associated having common interests, purposes, sensations, etc., Since association has a purpose, in the context of biological existence, the association or connection, or partnership between the energy seeker, and the energy provider is a meaningful event and not a simple, mechanical, physical event governed by the Laws of Interactions between Matter and Energy. There are Four Fundamental Interactions and they do not regulate or define this Interaction between Living matter and the Cosmic Force/Power/Energy. Living matter uses and exploits energy in a creative manner to build organic molecules and to break down organic molecules. The life processes are very similar and yet the results are totally different. While using energy mostly following a similar metabolic pathway, each organism supports its identity and individuality.
The understanding of cancer leads to the understanding of the spiritual substance of the cell.
Soul and Death:
The idea of ‘Soul’ always comes in the context of Death. If man is immortal, we will not be spending our time and energy discussing to verify the existence of an immortal principle.
The human subject has a limited life span and it arouses a sense of curiosity about the existence of something that could defy Death. I am trying to define the word ‘Soul’ in a manner to promote an understanding that ‘Soul’ is immortal if we look at man as an Association of individual living cells. We need to establish the Identity of that Individual for whose purpose or interest this Association of Individual living cells exists. If we think of Death as a final event, it is not supported by factual evidence. In this Association, death is a daily event. We simply fail to acknowledge this daily event as there is an immortal principle that is escaping this death experience. The Individual thinks that he is alive and sustains his Individuality without getting overwhelmed by the dying process that is continuous. While the human organism is changing its external appearance and identity all the time, the Individuality survives if ‘Soul’ the vital, or operating immortal principle is functioning. The issue or question about ‘transmigration’ of Soul would not arise if every living organism exists strictly as an Individual with an Individuality. As stated before,man has no choice and he must always exist as an Individual even when we use Reproductive Genetic Engineering Technology to produce identical clones with the same genome. The dissolution of matter may not change the Law of Conservation of Energy. If Soul is defined as the God Connection that gives the ability of energy acquisition, the Soul when removed from a physical object to which it has given Individuality, would operate as per the commands of the Controller of Force/Power/Energy. It provides the possibility of carrying the impressions of a previous state of existence into a new state of existence with a new identity and Individuality. During the life span of a given Individual, an association of cells in which death is a daily event, Soul is a continuous principle as its purpose and interest is to maintain Individuality of that Individual.
In a Living Cell, consciousness reflects its external environment and its internal condition or internal environment. The Living Cell knows, it is aware of its state, fact, and act of its Living. The Living Cell makes contact with its environment by using a cell membrane, a biological membrane, or a bio-membrane. If you carefully look at some of the functions of this membrane, you would discern that the Living Cell has consciousness or awareness of these functions. The Biological Membrane behaves in a conscious manner and it is not a simple, physical barrier between the Protoplasm, the Living Substance and its environment. If the term ‘soul’ describes a vital principle, or a source of Knowledge, it provides the information with which these functions could be performed. Some molecules and ions can freely move across this Bio-membrane and some are actively pumped in or out of the Cell that involves expenditure of energy. The Living Cell has the ability to recognize the condition of its nucleus, if the DNA is damaged, the Cell can initiate a process and cause its own dissolution.
Red Blood Cells display functional subordination to serve the purpose of the Whole Organism. Functional differentiation, and Functional Unity are important to support the existence of the Subject or Individual who is in reality an association of trillions of cells.
Identity and Individuality:
The understanding of cancer leads to the understanding of the spiritual substance of the cell.The understanding of cancer leads to the understanding of the spiritual substance of the cell.
The issue of spirituality, the nature of Soul and consciousness must be explored in the context of arriving at an understanding of man’s Identity and Individuality. If man is viewed as an association of trillions of cells, we need to know the Identity of that Subject who lives because of the functions of the trillions of cells. The purpose of consciousness at cellular level is to foster functional unity of the multicellular organism and to establish it as an Individual. In a multicellular organism, cells have short lives as individuals. The Subject or the whole organism has a life span of its own and it has effects on individual cells. Multicellularity is accompanied by adaptive subordination of all cells to the requirements of the organism as a whole. To achieve proper numerical balance between functionally related cell groups, the death of many cells is necessary for other cells to reach maturity. This programmed cell death plays an important role in embryological development. Such programmed cell death events are essential if the organism as a whole is to develop its normal final form. Waves of genetically driven cell deaths are critical to the proper modeling of organs and organ systems. We need to know and understand that death of cells is a must to establish the Identity and to sustain the Individuality of the human being.
The understanding of cancer leads to the understanding of the spiritual substance of the cell.
The dying process helps man to understand his Individuality. The Individuality is preserved while death is a daily event at the cellular level. The phenotype or the morphological appearance of the human Subject undergoes constant change during the Life journey and yet the Individuality remains unchanged.
The understanding of cancer leads to the understanding of the spiritual substance of the cell.
We recognize the death of this human Subject when his Soul departs from his body. Soul may be stated as an entity which is regarded as being immortal or spiritual part of the person. The Spirit of a dead person generally refers to a principle separate from the body and leading an existence of its own. If Soul is viewed as a Non-thing or Nothingness, it comes into the world of existence by entering the physical being at its conception which becomes conscious or aware of its existence. This consciousness has also existed in a previously existing Living Egg Cell which is the Mother of Life, Energy, and Knowledge. Consciousness by its very nature is immortal, it is eternal, and it has no birth or death. We recognize the arrival and departure of the new product during the Life-Death continuum where the Individuality is unaffected by the changes that are caused by the powerful influence of Time.
The understanding of cancer leads to the understanding of the spiritual substance of the cell.The understanding of cancer leads to the understanding of the spiritual substance of the cell.
The Status of Man in Nature:
The understanding of cancer leads to the understanding of the spiritual substance of the cell.
The First Book of Moses, The Old Testament Book of Genesis describes the story of Creation; in Chapter 2, verse 7, it narrates man’s creation: “And the LORD God formed man of the dust of the ground, and breathed into his nostrils the breath of life; and man became a living soul.”
“And the LORD God formed man of the dust of the ground, and breathed into his nostrils the breath of life; and man became a living soul.”Whole Dude at Whole Foods describes the Spiritual Connection between the Cell and its Energy Provider. The Discovery of Whole Spirituality at Whole Foods, Ann Arbor.Whole Dude at Whole Foods describes the Spiritual Connection between the Cell and its Energy Provider. The Discovery of Whole Spirituality at Whole Foods, Ann Arbor.Whole Dude at Whole Foods describes the Spiritual Connection between the Cell and its Energy Provider. The Discovery of Whole Spirituality at Whole Foods, Ann Arbor.
Whole Foods, Whole People, and Whole Planet are connected by a material substance called Protoplasm or Cytoplasm, a divine plan to provide nourishment to Life.
Whole Dude at Whole Foods describes the Spiritual Connection between the Cell and its Energy Provider. Rudolf Virchow, German pathologist in 1855 coined the biological dictum “OMNIS CELLULA E CELLULA” – All living cells arise only from pre-existing living cells.Whole Dude at Whole Foods describes the Spiritual Connection between the Cell and its Energy Provider. Photograph, 1893. Rudolf Virchow (1821-1902).
Whole Dude – Whole Samsara: The Rudi-Grant Connection faces the Fear of Samsara.
Excerpt: The article looks into the concept of ‘Samsara,’ which is seen in Indian traditions as a representation of life’s journey – a challenging swim across an unknown and treacherous ocean. This journey incites a fear called ‘Fear of Samsara,’ contributing to feelings of apprehension and the intense fear of the human condition. This fear is considered unique to Indian cultural traditions, differentiating them from other global traditions like Christianity, Islam, and Judaism whose followers primarily fear the Lord. However, despite this anxiety, individuals rely on chants and signs such as ‘Abhaya Mudra’ (a sign of fearlessness) from deities for support and guidance during this strenuous journey.
Whole Dude – Whole Samsara: Defining Indian Identity – The Fear of Samsara. Samsara portrays the picture of life’s journey as a tedious,difficult and challenging swim across an unknown,uncharted and treacherous ocean.
The cultural traditions that originated in India motivate people to seek refuge or shelter at the Feet of the Lord by evoking a sense of fear and this fear is described as the fear of ” SAMSARA.” Samsara or Bhava describes the viewpoint about the human condition and deals with the problems of human existence. It contributes to a sense of apprehension and anxiety and the attitude it generates is one of intense fear and helplessness.
Whole Dude – Whole Samsara: Defining Indian Identity-The Fear of Samsara. Samsara portrays the picture of life’s journey as a tedious,difficult and challenging swim across an unknown,uncharted and treacherous ocean.
In one great leap of faith, Lord Hanuman jumps over the sea with utmost ease, whereas crossing the sea evokes only a sense of fear in my heart. I derive some hope from the legend about the land bridge (SETU) built by the army of monkeys.The Sea God promised them that the rocks and boulders used for the construction of the bridge will be held in place and stay afloat. He did that to please Lord Rama. During my perilous journey across the ocean of SAMSARA, I use the name “RAMA” and stay afloat.
Whole Dude – Whole Samsara: Samsara portrays the picture of life’s journey as a tedious,difficult and challenging swim across an unknown,uncharted and treacherous ocean. In the fearful journey described as ‘SAMSARA’, I use Lord Rama’s name as a ‘Life Jacket’ and also the name serves like a Beacon of Hope and provides a sense of direction while journeying across an uncharted, treacherous sea.
“The fear of the Lord is the beginning of Wisdom” says the Holy Bible, The Book of Proverbs, Chapter1, verse 7.
Whole Dude – Whole Samsara: Defining Indian Identity – The Fear of Samsara. Samsara portrays the picture of life’s journey as a tedious,difficult and challenging swim across an unknown,uncharted and treacherous ocean.
For the religious traditions that originated outside of India such as Judaism, Christianity and Islam, the fear of the Lord could be a primary motivating factor to seek the worship of the Lord. On the contrary, the religious traditions that originated in the Land of India, do not encourage their adherents to entertain any such fear of the Lord. In the Indian traditions, the Lord or the Deity that Indians choose to worship would receive them with a sign that proclaims ” Be Fearless.” The Lord reassures them with a sign that is popularly described as ABHAYA HASTA or ABHAYA MUDRA. In Indian literature, countless number of images, idols, paintings and drawings, there are invariable references to a consistent message of ABHAYA and naturally Indians are less concerned with ” The Fear of the Lord.”
Whole Dude – Whole Samsara – Whole Journey. Abhaya Mudra and Abhaya Hasta describe the positioning of hand to indicate as a sign that overcomes the sense of fear.Whole Dude – Whole Samsara: Defining Indian Identity – The Fear of Samsara. Samsara portrays the picture of life’s journey as a tedious,difficult and challenging swim across an unknown,uncharted and treacherous ocean.Whole Dude – Whole Samsara: Defining Indian Identity – The Fear of Samsara. Samsara portrays the picture of life’s journey as a tedious,difficult and challenging swim across an unknown,uncharted and treacherous ocean.
Samsara portrays the picture of life’s journey as a tedious,difficult and challenging swim across an unknown,uncharted and treacherous ocean.
Whole Dude – Whole Samsara: Defining Indian Identity – The Fear of Samsara. Samsara portrays the picture of life’s journey as a tedious,difficult and challenging swim across an unknown,uncharted and treacherous ocean.Whole Dude – Whole Samsara: Defining Indian Identity – The Fear of Samsara. Samsara portrays the picture of life’s journey as a tedious,difficult and challenging swim across an unknown,uncharted and treacherous ocean.Whole Dude – Whole Samsara: Defining Indian Identity – The Fear of Samsara. Samsara portrays the picture of life’s journey as a tedious,difficult and challenging swim across an unknown,uncharted and treacherous ocean.Whole Dude – Whole Samsara: Defining Indian Identity – The Fear of Samsara. Samsara portrays the picture of life’s journey as a tedious,difficult and challenging swim across an unknown,uncharted and treacherous ocean.
Samsara is also depicted as a serious disease entity afflicting a person’s health and is referred to as “Bhava Roga.” Others view Samsara as existence in a bottomless deep pit (“Aghada”)or that of being trapped in a deep well from where an escape would not be easy. The fear of Samsara/Bhava, the fear of the human condition, has nothing to do with physical courage. The powerful idea of Samsara inspires a sense of fear in the hearts of even the most courageous of all people. Cultural traditions that have their roots in the other parts of this planet may not be aware of this kind of fear and hence the fear of Samsara could be viewed as a feature that defines and molds the Indian Identity. Indians chant the Lord’s name as a medicine to cure this terrible disease and they seek Lord’s protection to reach the shore and complete the journey across the ocean.There are numerous references in the Indian literature.
Whole Dude – Whole Samsara – Whole Journey. My Life Journey started in Mylapore, Madras (Chennai City) on Kutchery Street near the Marina Beach.
Human existence is beset with countless uncertainties and difficulties which may arrive without any prior warning from different directions in an unpredictable manner. It is rational to approach life with a sense of apprehension and seek the help of the Lord who graciously held His right hand in a show of compassion and receives with a greeting of “Abhaya” and is willing to banish the fear of Samsara.
Whole Dude – Whole Samsara: Defining Indian Identity-The Fear of Samsara. The LORD is Male and Female at one and the same time. The right hand is held in the pose of Abhaya Mudra. Samsara portrays the picture of life’s journey as a tedious,difficult and challenging swim across an unknown,uncharted and treacherous ocean.Whole Dude – Whole Samsara – Whole JourneyWhole Dude – Whole Samsara: The Rudi-Grant Connection presents the post, The Fear of the Lord vs The Fear of Samsara
Whole Dude - Whole Concept 